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| 1 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 29 |
| 2 | Developmental dysplasia of the hip in the newborn: A systematic review显示文摘Developmental dysplasia of the hip(DDH) denotes a wide spectrum of conditions ranging from subtle acetabular dysplasia to irreducible hip dislocations. Clinical diagnostic tests complement ultrasound imaging in allowing diagnosis, classification and monitoring of this condition. Classification systems relate to the alpha and beta angles in addition to the dynamic coverage index(DCI). Screening programmes for DDH show considerable geographic variation; certain risk factors have been identified which necessitate ultrasound assessment of the newborn. The treatment of DDH has undergone significant evolution, but the current gold standard is still the Pavlik harness. Duration of Pavlik harness treatment has been reported to range from 3 to 9.3 mo. The beta angle, DCI and the superior/lateral femoral head displacement can be assessed via ultrasound to estimate the likelihood of success. Success rates of between 7% and 99% have been reported when using the harness to treat DDH. Avascular necrosis remains the most devastating complication of harness usage with a reported rate of between 0% and 28%. Alternative non-surgical treatment methods used for DDH include devices proposed by LeD amany, Frejka, Lorenz and Ortolani. The Rosen splint and Wagner stocking have also been used for DDH treatment. Surgical treatment for DDH comprises open reduction alongside a combination of femoral or pelvic osteotomies. Femoral osteotomies are carried out in cases of excessive anteversion or valgus deformity of the femoral neck. The two principal pelvic osteotomies most commonly performed are the Salter osteotomy and Pemberton acetabuloplasty. Serious surgical complications include epiphyseal damage, sciatic nerve damage and femoral neck fracture. | Vivek Gulati Kelechi Eseonu Junaid Sayani Nizar Ismail Chika Uzoigwe Muhammed Zaki Choudhury Pooja Gulati Adeel Aqil Saket Tibrewal | 2013 | World Journal of Orthopedics2013，4，2： | 29 |
| 3 | Gastric carcinogenesis显示文摘Gastric cancer is the second most common cancer worldwide and the second most common cause of cancer-related deaths. Despite complete resection of gastric cancer and lymph node dissection, as well as improvements in chemotherapy and radiotherapy, there are still 700 000 gastric cancer-related deaths per year worldwide and more than 80% of patients with advanced gastric cancer die of the disease or recurrent disease within 1 year after diagnosis. None of the treatment modalities we have been applying today can influence the overall survival rates:at present, the overall 5-year relative survival rate for gastric cancer is about 28%. Cellular metaplasia due to chronic inflammation, injury and repair are the most documented processes for neoplasia. It appears that chronic inflammation stimulates tumor development and plays a critical role in initiating, sustaining and advancing tumor growth. It is also evident that not all inflammation is tumorigenic. Additional mutations can be acquired, and this leads to the cancer cell gaining a further growth advantage and acquiring a more malignant phenotype. Intestinalization of gastric units, which is called 'intestinal metaplasia'; phenotypic antralization of fundic units, which is called 'spasmolytic polypeptide-expressing metaplasia'; and the development directly from the stem/progenitor cellzone are three pathways that have been described for gastric carcinogenesis. Also, an important factor for the development of gastrointestinal cancers is peritumoral stroma. However, the initiating cellular event in gastric metaplasia is still controversial. Understanding gastric carcinogenesis and its precursor lesions has been under intense investigation, and our paper attempts to highlight recent progress in this field of cancer research. | Ismail Gomceli Baris Demiriz Mesut Tez | 2012 | World Journal of Gastroenterology2012，18，37： | 25 |
| 4 | Endoscopic retrograde cholangiopancreatography during pregnancy without radiation显示文摘AIM: To present our experience with pregnant patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) without using radiation, and to evaluate the acceptability of this alternative therapeutic pathway for ERCP during pregnancy. METHODS: Between 2000 and 2008, six pregnant women underwent seven ERCP procedures. ERCP was performed under mild sedoanalgesia induced with pethidine HCl and midazolam. The bile duct was cannulated with a guidewire through the papilla. A catheter was slid over the guidewire and bile aspiration and/or visualization of the bile oozing around the guidewire was used to confirm correct cannulation. Following sphincterotomy, the bile duct was cleared by balloon sweeping. When indicated, stents were placed. Confirmation of successful biliary cannulation and stone extraction was made by laboratory, radiological and clinical improvement. Neither fluoroscopy nor spot radiography was used during the procedure. RESULTS: The mean age of the patients was 28 years (range, 21-33 years). The mean gestational age for the fetus was 23 wk (range, 14-34 wk). Five patients underwent ERCP because of choledocholithiasis and/orcholedocholithiasis-induced acute cholangitis. In one case, a stone was extracted after precut papillotomy with a needle-knife, since the stone was impacted. One patient had ERCP because of persistent biliary fistula after hepatic hydatid disease surgery. Following sphincterotomy, scoleces were removed from the common bile duct. Two weeks later, because of the absence of fistula closure, repeat ERCP was performed and a stent was placed. The fistula was closed after stent placement. Neither post-ERCP complications nor premature birth or abortion was seen. CONCLUSION: Non-radiation ERCP in experienced hands can be performed during pregnancy. Stent placement should be considered in cases for which complete common bile duct clearance is dubious because of a lack of visualization of the biliary tree. | Adem Akcakaya Orhan Veli Ozkan Ismail Okan Orhan Kocaman Mustafa Sahin | 2009 | World Journal of Gastroenterology2009，15，29： | 17 |
| 5 | 秸秆覆盖和生物炭对玉米田间地温和产量的影响显示文摘为了探究秸秆覆盖和生物炭对土壤温度和玉米产量的影响,设置2种覆盖方式(不覆盖和秸秆覆盖)和3个生物炭施用量水平(0、4和12 t·hm-2)的田间小区试验,对玉米田间地温和产量及产量性状进行分析。结果表明:秸秆覆盖显著降低土壤温度,降温效应在不同土层上表现为随土层深度的增大而减小,在全生育期内表现为前期大、后期小的变化趋势;在不同覆盖条件下,生物炭对地温的影响有所不同,在不覆盖条件下,生物炭处理有增温保温效应,随生物炭施用量的增大而增大;在秸秆覆盖条件下,生物炭对0~10 cm土层有降温效应,而对15~25 cm土层则有增温效应;秸秆覆盖和生物炭处理均能显著提高玉米产量、产量构成和经济系数,其中秸秆覆盖和12 t·hm-2生物炭组合处理的玉米产量最高,产量、产量构成和经济系数显著高于对照,较对照分别提高24.2%、6.4%~15.7%和15.0%;各产量构成因素中穗长和行粒数对产量影响最大,其中穗长与产量表现为负相关关系,行粒数与产量表现为正相关关系。 | 戴皖宁 王丽学 Ismail Khan 王晓帆 李振华 | 2019 | 生态学杂志2019，38，3： | 16 |
| 6 | CeO_2-TiO_2 as a visible light active catalyst for the photoreduction of CO_2 to methanol显示文摘The performance of CeO2-TiO2 photocatalyst for the photocatalytic reduction of CO2 into methanol was studied under visible light irradiation. The as-prepared catalysts were characterized for their structural, textural and optical properties using X-ray diffraction(XRD), field emission scanning electron microscopy(FESEM), X-ray photoelectron spectroscopy(XPS), nitrogen physisorption analysis, UV-vis spectroscopy and photoluminescence(PL) spectroscopy. The characterization results indicated that the presence of CeO2 stabilized the anatase phase of TiO2, decreased its crystallite size, increased the surface area, reduced the band gap energy and lowered the rate of electron-hole pair recombination. The CeO2-TiO2 photocatalyst showed an increased methanol yield of 18.6 μmol/g under visible light irradiation, compared to the bare TiO2(6.0 μmol/g). | Hamidah Abdullah Maksudur R.Khan Manoj Pudukudy Zahira Yaakob Nur Aminatulmimi Ismail | 2015 | Journal of Rare Earths2015，33，11： | 15 |
| 7 | 金属-有机框架材料对废水中污染物的吸附研究进展显示文摘可用的清洁水资源缩减已成为全球面临的重要危机。引起该危机的主要原因是各种污染物因生产、生活或事故排入水体导致水体污染。因此,解决水资源危机的关键在于对污水处理和再生。多种污水处理和再生方法应运而生,其中吸附法因处理效率高、操作简便、成本低而被广泛应用到污水处理中。吸附法的关键在于吸附剂的选择和应用。应用于水处理的传统吸附剂,如活性炭、沸石、天然粘土、活性氧化铝等,在面对复杂水体环境和各种性质迥异的污染物时已不能符合水污染处理的更高标准。因此,新型吸附剂的开发与应用成为吸附领域研究热点。金属有机框架(Metal-organic frame,MOF)材料,一类金属离子或金属簇与有机配体之间自组装配位形成的化合物,具有高比表面积、高孔隙率和可控的孔结构,已成为吸附领域冉冉升起的新星。目前MOF材料作为水处理吸附剂的研究主要集中在:(1)各种MOF材料对不同污染物的吸附性能研究,以揭示相关吸附规律;(2)MOF材料自身功能化或MOF复合材料的制备,以改善自身稳定性,提高其吸附性能或实现选择性吸附;(3)MOF衍生碳吸附材料的研究,以应对恶劣水体环境或极端水处理条件。本文对单一MOF材料、功能化MOF材料、MOF衍生碳材料吸附去除水体中有机染料、其他有机污染物、重金属离子的相关研究进行了综述。概述了多种MOF材料对不同污染物的吸附性能,总结了针对吸附应用的多种MOF功能化方式及其吸附效果的改进,归纳了多种MOF衍生碳材料作为吸附剂在水处理中的应用,指出了目前MOF吸附材料在水处理中存在的主要问题,并提出了解决这些问题的思路。 | 附青山 张磊 张伟 Ismail Pir Muhammad 陈雪丹 龚敏 何平 王祖波 | 2021 | 材料导报2021，35，11： | 15 |
| 8 | Root-Specific Transcript Profiling of Contrasting Rice Genotypes in Response to Salinity Stress显示文摘提高的咸度强加渗透并且离子毒性在生活上强调房间并且要求大量的回答以便启用植物幸存。在在米饭( Oryza sativa )介绍抄本层次的更早的工作上造 FL478 射击,盐容忍的 indica recombinant 生来的线,和 IR29 ,盐敏感的栽培变种,抄本层次在这二就职的根以及在二另外的盐容忍的 indica 遗传型的根被比较, landrace Pokkali 和 recombinant 生来的线 IR63731 。这研究的目的是比较抄本在敏感并且容忍的线以便多半识别基因涉及工厂咸度忍耐,而非响应咸度本身。有到咸度忍耐的已知的连接的几个基因家庭的抄本侧面被描述(例如 HKT, NHX ) 。通过他们的盐应答,抄本层次,或 chromosomal 地点识别的一套基因的通常认为的功能(即在为咸度忍耐的 QTL 下面) 也被讨论。最后,在 FL478 的 Saltol 区域的父母起源进一步被调查。总的来说,介绍的数据集看起来柔韧,这个系统能为涉及咸度忍耐的新奇基因的发现提供可靠策略,似乎可能。 | Olivier Cotsaftis Darren Plett Alexander A.T. Johnson Harkamal Walia Clyde Wilson Abdelbagi M. Ismail Timothy J. Close Mark Tester Ute Baumann | 2011 | Molecular Plant2011，4，1： | 14 |
| 9 | Energy-efficient Virtual Machine Allocation Technique Using Flower Pollination Algorithm in Cloud Datacenter:A Panacea to Green Computing显示文摘Cloud computing has attracted significant interest due to the increasing service demands from organizations offloading computationally intensive tasks to datacenters.Meanwhile,datacenter infrastructure comprises hardware resources that consume high amount of energy and give out carbon emissions at hazardous levels.In cloud datacenter,Virtual Machines(VMs)need to be allocated on various Physical Machines(PMs)in order to minimize resource wastage and increase energy efficiency.Resource allocation problem is NP-hard.Hence finding an exact solution is complicated especially for large-scale datacenters.In this con text,this paper proposes an Energy-oriented Flower Pollination Algorithm(E-FPA)for VM allocation in cloud datacenter environments.A system framework for the scheme was developed to enable energy-oriented allocation of various VMs on a PM.The allocation uses a strategy called Dynamic Switching Probability(DSP).The framework finds a near optimal solution quickly and balances the exploration of the global search and exploitation of the local search.It considers a processor,storage,and memory constraints of a PM while prioritizing energy-oriented allocation for a set of VMs.Simulations performed on MultiRecCloudSim utilizing planet workload show that the E-FPA outperforms the Genetic Algorithm for Power-Aware(GAPA)by 21.8%,Order of Exchange Migration(OEM)ant colony system by 21.5%,and First Fit Decreasing(FFD)by 24.9%.Therefore,E-FPA significantly improves datacenter performance and thus,enhances environmental sustainability. | Mohammed Joda Usman Abdul Samad Ismail Hassan Chizari Gaddafi Abdul-Salaam Ali Muhammad Usman Abdulsalam Yau Gital Omprakash Kaiwartya Ahmed Aliyu | 2019 | Journal of Bionic Engineering2019，16，2： | 13 |
| 10 | Increased hepcidin expression in colorectal carcinogenesis显示文摘AIM:To investigate whether the iron stores regulator hepcidin is implicated in colon cancer-associated anae- mia and whether it might have a role in colorectal car- cinogenesis. METHODS: Mass spectrometry (MALDI-TOF MS and SELDI-TOF MS) was employed to measure hepcidin in urine collected from 56 patients with colorectal cancer. Quantitative Real Time RT-PCR was utilised to determine hepcidin mRNA expression in colorectal cancer tissue. Hepcidin cellular localisation was determined using im- munohistochemistry. RESULTS: We demonstrate that whilst urinary hepcidin expression was not correlated with anaemia it was posi- tively associated with increasing T-stage of colorectal cancer (P < 0.05). Furthermore, we report that hepcidin mRNA is expressed in 34% of colorectal cancer tissue specimens and was correlated with ferroportin repres- sion. This was supported by hepcidin immunoreactivity in colorectal cancer tissue. CONCLUSION: We demonstrate that systemic hepcidin expression is unlikely to be the cause of the systemic anaemia associated with colorectal cancer. However, we demonstrate for the first time that hepcidin is expressed by colorectal cancer tissue and that this may represent a novel oncogenic signalling mechanism. | Douglas G Ward Keith Roberts Matthew J Brookes Howard Joy Ashley Martin Tariq Ismail Robert Spychal Tariq Iqbal Chris Tselepis | 2008 | World Journal of Gastroenterology2008，14，9： | 12 |
| 11 | 精索静脉曲张导致的睾丸功能障碍发病机理中TNF相关的调亡诱导配体的角色显示文摘不育男性中频发的精索静脉曲张备受关注,面向治疗的分子水平的研究也随之增加。本研究的目的是探讨大鼠模型中肿瘤坏死因子相关凋亡诱导配体(TRAIL)及其受体在精索静脉曲张起的睾丸功能障碍中的作用。大鼠被随机分为三组:对照组,假手术组和精索静脉曲张组。部分结扎左肾静脉与左睾丸构建大鼠精索静脉曲张模型。对手术13周后的大鼠进行分析。睾丸细胞内DNA片段程度用末端脱氧核苷酸转移酶的脱氧尿苷三磷酸缺口未端标记法(TUNEL)检测。用约翰逊得分评估肾小管退化情况。用免疫组化和Westernblot技术检测TRAIL及其受体的表达。检测了细胞凋亡指数,约翰逊得分,TRAIL和TRAIL受体的表达。数据以平均值±标准偏差(s.d.)表示,并用计算机软件进行了分析。用Kruskal—Wallis和Dunn’s多重比较试验进行数捌分析。与假手术组和对照组相比,精索静脉曲张的大鼠生殖细胞凋亡指数增加(P=0.0031),约翰逊得分显著下降(P〈0.0001)。免疫组化和Western blot分析表明,精索静脉曲张后,生殖细胞中的TRAIL-R1和TRAIL—R4的表达增加,TRAIL—R2的表达下降。在TRAIL和TRAIL—R3受体的表达上,各组间没有显著差异。这一研究结果表明,TRAIL及其受体可能神精索静脉曲张引起的罩丸功能障碍的发病机制中有潜在的作用。 | Orcun Celik Omer Kutlu Merih Tekcan CUer Celik-Ozenci Ismail T Koksal | 2013 | Asian Journal of Andrology2013，15，2： | 12 |
| 12 | Management of tear trough deformity with and without tear trough-orbicularis retaining ligament complex release in transconjunctival blepharoplasty: a comparative study显示文摘AIM: To evaluate the effect of releasing the orbicularis retaining ligament(ORL) complex of the tear trough combined with the transconjunctival blepharoplasty in the surgical management of tear trough deformity compared with the effect of blepharoplasty alone. METHODS: A prospective, randomized(by closed envelope technique), controlled surgical trial which included 50 patients(100 eyes) with bilateral visible tear trough deformity and lower eyelid fat bulging, was divided into two groups where 25 patients(50 eyes) had tear trough-ORL release with blepharoplasty and 25 patients(50 eyes) didn't. Qualitative and quantitative assessments of tear trough deformity were done at 6 mo postoperatively, achieving grade 0 or 1 of Barton's classification was considered a success. Standardized photographic documentation of each patient was done pre and postoperatively, also assessment of the patients' satisfaction postoperatively was done and ranked as excellent, very good, good or fair. RESULTS: There was statistically significant difference between the two groups in the overall aesthetic results postoperatively regarding the qualitative and quantitative analysis of the tear trough deformity, where patients who had tear trough-ORL complex release had more successful outcomes than those of the second group. CONCLUSION: ORL release should be done in patients with tear trough deformity in order to release the tethering effect of this ligament which causes the prominence of the naso jugal groove. | Tamer Ismail Gawdat Engy Abd Eltawab Elsherif Yomna Amr Alahmadawy Yehia Salah Eldin Mostafa | 2019 | International Journal of Ophthalmology(English edition)2019，12，1： | 12 |
| 13 | 应激源感知的文化和性别差异:对留学中国的非洲学生和西方学生的跨文化研究显示文摘本研究对留学中国的非洲和西方留学生进行了留学应激的调查研究 (studyabroadstresssurvey ,SASS) ,旨在确定应激源感知是否存在文化差异 ,同时为留学生的应激感知研究创建一个基础。结果表明 ,最常感知到的应激源来自学术和人际交往两个方面。文化差异和性别差异仅表现在部分具体的应激源感知上 ,总体上的应激源感知并未发现任何组间差异。男女留学生都曾经体验到日常压力所引起的较高的应激 ,而在对学业成绩不佳、课程不足等应激源的感知上性别差异较小。 | Ismail Hussein Hashim 周颖 杨治良 | 2003 | 心理科学2003，26，5： | 12 |
| 14 | Limbal stem cells: Central concepts of corneal epithelial homeostasis显示文摘A strong cohort of evidence exists that supports the localisation of corneal stem cells at the limbus. The distinguishing characteristics of limbal cells as stem cells include slow cycling properties, high proliferative potential when required, clonogenicity, absence of differentiation marker expression coupled with positive expression of progenitor markers, multipotency, centripetal migration, requirement for a distinct niche environment and the ability of transplanted limbal cells to regenerate the entire corneal epithelium. The existence of limbal stem cells supports the prevailing theory of corneal homeostasis, known as the XYZ hypothesis where X represents proliferation and stratification of limbal basal cells, Y centripetal migration of basal cells and Z desquamation of superficial cells. To maintain the mass of cornea, the sum of X and Y must equal Z and very elegant cell tracking experiments provide strong evidence in support of this theory. However, several recent stud-ies have suggested the existence of oligopotent stem cells capable of corneal maintenance outside of the limbus. This review presents a summary of data which led to the current concepts of corneal epithelial homeostasis and discusses areas of controversy surrounding the existence of a secondary stem cell reservoir on the corneal | Jinny J Yoon Salim Ismail Trevor Sherwin | 2014 | World Journal of Stem Cells2014，6，4： | 11 |
| 15 | Synthesis of linear low-density polyethylene-g-poly(acrylic acid)-co-starch/organo-montmorillonite hydrogel composite as an adsorbent for removal of Pb(Ⅱ) from aqueous solutions显示文摘The purpose of this work is to remove Pb(II) from the aqueous solution using a type of hydrogel composite. A hydrogel composite consisting of waste linear low density polyethylene, acrylic acid, starch, and organo-montmorillonite was prepared through emulsion polymerization method. Fourier transform infrared spectroscopy(FTIR), Solid carbon nuclear magnetic resonance spectroscopy(CNMR)), silicon-29 nuclear magnetic resonance spectroscopy(Si NMR)), and X-ray diffraction spectroscope((XRD) were applied to characterize the hydrogel composite. The hydrogel composite was then employed as an adsorbent for the removal of Pb(II) from the aqueous solution. The Pb(II)-loaded hydrogel composite was characterized using Fourier transform infrared spectroscopy(FTIR)),scanning electron microscopy(SEM)), and X-ray photoelectron spectroscopy((XPS)). From XPS results, it was found that the carboxyl and hydroxyl groups of the hydrogel composite participated in the removal of Pb(II). Kinetic studies indicated that the adsorption of Pb(II)followed the pseudo-second-order equation. It was also found that the Langmuir model described the adsorption isotherm better than the Freundlich isotherm. The maximum removal capacity of the hydrogel composite for Pb(II) ions was 430 mg/g. Thus, the waste linear low-density polyethylene-g-poly(acrylic acid)-co-starch/organo-montmorillonite hydrogel composite could be a promising Pb(II) adsorbent. | Maryam Irani Hanafi Ismail Zulkifli Ahmad Maohong Fan | 2015 | Journal of Environmental Sciences2015，27，1： | 11 |
| 16 | C3-Modules显示文摘在如果每当 A 和 B 是 M 和 B=0 的直接被加数时,那么 B 是 M 的一个被加数,模块 M 被称为一个 C3 模块的地方, Utumi 在 self-injective 戒指上识别的连续性条件之一是 C3 条件。除了 injective 和 direct-injective 模块, C3 模块的班包括 semisimple,连续、不能分解、常规的模块。确实,每枚可交换的戒指是一枚 C3 戒指。在这份报纸,我们以 C3 条件提供模块的上述提及的班的一个一般、统一的处理,并且建立戒指的几个众所周知的班的新描述。 | Ismail Amin Yasser Ibrahim Mohamed Yousif | 2015 | Algebra Colloquium2015，22，4： | 11 |
| 17 | Hypoxia inducible factor-1αaccumulation in steatotic liver preservation:Role of nitric oxide显示文摘AIM:To examine the relevance of hypoxia inducible factor(HIF-1)and nitric oxide(NO)on the preservation of fatty liver against cold ischemia-reperfusion injury(IRI). METHODS:We used an isolated perfused rat liver model and we evaluated HIF-1αin steatotic and non-steatotic livers preserved for 24 h at 4℃in University of Wisconsin and IGL-1 solutions,and then subjected to 2 h of normothermic reperfusion.After normoxic reperfusion,liver enzymes,bile production,bromosulfophthalein clearance,as well as HIF-1αand NO[endothelial NO synthase(eNOS)activity and nitrites/nitrates]were also measured.Other factors associated with the higher susceptibility of steatotic livers to IRI,such as mitochondrial damage and vascular resistance were evaluated. RESULTS:A significant increase in HIF-1αwas found in steatotic and non-steatotic livers preserved in IGL-1 after cold storage.Livers preserved in IGL-1 showed a significant attenuation of liver injury and improvement in liver function parameters.These benefits were enhanced by the addition of trimetazidine(an antiischemic drug),which induces NO and eNOS activation, to IGL-1 solution.In normoxic reperfusion,the presence of NO favors HIF-1αaccumulation,promoting also the activation of other cytoprotective genes,such as hemeoxygenase-1. CONCLUSION:We found evidence for the role of the HIF-1α/NO system in fatty liver preservation,especially when IGL-1 solution is used. | Mohamed Amine Zaouali Ismail Ben Mosbah Eleonora Boncompagni Hassen Ben Abdennebi Maria Teresa Mitjavila Ramon Bartrons Isabel Freitas Antoni Rimola Joan Roselló-Catafau | 2010 | World Journal of Gastroenterology2010，16，28： | 11 |
| 18 | 铝合金及铝金属基复合材料搅拌摩擦焊接工艺的研究进展显示文摘焊接在汽车、航空航天、机器人、建筑等行业具有重要的作用。这些行业常用非焊接方法制造很多铝合金零部件或系统。然而,由于不可热处理合金的存在、孔隙、凝固和熔融裂纹等因素,铝合金的熔焊具有挑战性。许多制造商采用传统的空气搅拌摩擦焊(FSW)焊接合金和异质材料,也有许多研究报道关于该传统FSW技术在焊接金属和聚合物材料,尤其是铝合金和铝基复合材料方面的缺点。近年来,为了克服传统FSW技术焊接铝合金的缺点,开发出很多其他FSW技术,例如水下搅拌摩擦焊(UFSW)和振动搅拌摩擦焊(VFSW)等。本文综述了近年来铝合金及铝基复合材料(AlMMCs)搅拌摩擦焊接工艺的研究进展,讨论了传统的FSW技术和最先进的FSW工艺参数对铝合金和铝基复合材料焊接质量和强度的影响,并比较了每种方法的优缺点。VFSW在能源效率和经济成本方面具有优势,并可根据应用情况进行多种改进,是焊接铝接头的一种可行的选择。然而,目前对Al MMCs搅拌摩擦焊的研究明显较少,这应给予足够的关注。 | John VICTOR CHRISTY Abdel-Hamid ISMAIL MOURAD Muhammad M.SHERIF B.SHIVAMURTHY | 2021 | Transactions of Nonferrous Metals Society of China2021，31，11： | 11 |
| 19 | Ultrasound-guided transrectal extended prostate biopsy:a prospective study显示文摘Aim: To evaluate the diagnostic value of the 10 systematic transrectal ultrasound-guided (TRUS) prostate biopsy compared with the sextant biopsy technique for patients with suspected prostate cancer. Methods: One hundred and fifty-two patients with suspected prostate cancer were included in the study. Patients were entered in the study because they presented with high levels of prostate specific antigen (PSA) (over 4ng/mL) and/or had undergone an abnormal digital rectal examination (DRE). In addition to sextant prostate biopsy cores, four more biopsies were obtained from the lateral peripheral zone with additional cores from each suspicious area revealed by transrectal ultrasound. Sextant, lateral peripheral zone and suspicious area biopsy cores were submitted separately to the pathological department. Results: Cancer detection rates were 27.6%(42/152) and 19.7%(30/152) for the 10-core and sextant core biopsy protocols, respectively. Adding the lateral peripheral zone (PZ) to the sextant prostate biopsy showed a 28.6%(12/42) increase in the cancer detection rate in patients with positive prostate cancer (P<0.01).The cancer detection rate in patients who presented with elevated PSA was 29.3%(34/116). When serum PSA was 4-10ng/mL TRUS-guided biopsy detected cancer in 20.6%, while the detection rate was 32.4% and 47.0% when serum PSA was 10-20ng/mL and above 20ng/mL, respectively. Conclusion: The 10 systematic TRUS-guided prostate biopsy improves the detection rate of prostate cancer by 28.6% when compared with the sextant biopsy technique alone, without increase in the morbidity. We therefore recommend the 10-core biopsy protocol to be the preferred method for early detection of prostate cancer. | Mohammed Ahmed Al-Ghazo Ibrahim Fathi Ghalayini Ismail Ibrahim Matalka | 2005 | Asian Journal of Andrology2005，7，2： | 10 |
| 20 | Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer显示文摘AIM:To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer.METHODS:One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study.The serum concentrations of MMP-1 and TIMP-1 in these patients and in fifty healthy controls were determined using an enzyme-linked immunosorbent assay.RESULTS:Higher serum MMP-1 and TIMP-1 levels were observed in patients than in controls (P < 0.001).Serum MMP-1 and TIMP-1 levels were positively associated with morphological appearance,tumor size,depth of wall invasion,lymph node metastasis,liver metastasis,perineural invasion,and pathological stage.They were not significantly associated with age,gender,tumor location,or histological type.CONCLUSION:Increased MMP-1 and TIMP-1 were associated with gastric cancer.Although these markers are not good markers for diagnosis,these markers show in advanced gastric cancer. | Ozgur Kemik Ahu Sarbay Kemik Aziz Sümer Ahmet Cumhur Dulger Mine Adas Huseyin Begenik Ismail Hasirci Ozkan Yilmaz Sevim Purisa Erol Kisli Sefa Tuzun Cetin Kotan | 2011 | World Journal of Gastroenterology2011，17，16： | 10 |
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