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23篇 您的检索式:作者名="Hartmut W"
    题名 作者 年代 出处 被引量
1Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound显示文摘AIM:To evaluate whether contrast enhanced ultrasound(CEUS) might also be used for response prediction and early response evaluation in patients receiving bevacizumab based chemotherapy for metastasized colorectal cancer.METHODS:Thirty consecutive patients with non primary resectable liver metastases from colorectal cancer underwent CEUS before treatment(CEUS date 1) and before the second(CEUS date 2) and fourth(CEUS date 3) cycle of bevacizumab based chemotherapy.Three parameters [PEAK,Time to peak(TTP) and RISE RATE]were correlated with radiological response.RESULTS:For neoadjuvant purpose a reduction of tumour mass was required to assume clinical response.Based on these response criteria there was a significant(P < 0.001) correlation in TTP between metastases of responders(9.08 s) and non-responders(14.76 s) archived on CEUS date 1.By calculating a standardized quotient(metastases divided by normal liver tissue) we were able to define a cut off,predicting response with a sensitivity of 92.3 % and a specificity of 100 %.To reflect a palliative intention only those patients with progressive disease were classified as non-responders.In this stetting TTP was also significantly(P < 0.01) different between responders and non-responders.In contrast,Peak and Rise rate did not show any significant difference between responder and non-responder.CONCLUSION:CEUS might serve as a surrogate marker to predict treatment response in patients with metastasized colorectal cancer who receive antiangiogenic therapy.Ramin Schirin-Sokhan Ron Winograd Christoph Roderburg Jhenee Bubenzer Nicole Cabral do ó Dorothee Guggenberger Hartmut Hecker Christian Trautwein Jens J W Tischendorf 2012World Journal of Gastroenterology2012,18,6:16
2Ertapenem:the new carbapenem 5 years after first FDA licensing for clinical practice显示文摘Olaf B Hartmut D Tobias W 0,,02:1
3Determination of total aryte- noids and chlorophylls a and b of leaf extracts in differ- ent solvents显示文摘Hartmut K L Alan R W 1983Bioche Soc Trans1983,11,:1
4Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy显示文摘Kevin J Martin Klaus Olgaard Jack W Coburn Giorgio M Coen Masafumi Fukagawa Craig Langman Hartmut H Malluche James T McCarthy Shaul G Massry Otto Mehls Isidro B Salusky Justin M Silver Miroslaw T Smogorzewski Eduardo M Slatopolsky Linda McCann 2004American Journal of Kidney Diseases2004,,3:1
5Parent bisphenol A accumula-tion in the human maternal-fetal-placental unit显示文摘Gilbert S Werner W Hartmut H 2002Environ HealthPerspect2002,110,:1
6Chronic inflammatory cardiomyopathy of interferon-overex- pressing transgenic ,nice is mediated by tumor necrosis factor-a显示文摘Michael T Philip W Hartmut K 2012Am J Pathol2012,180,1:1
7Tracing the molecular pathogenesis of antiphos- pholipid syndrome 显示文摘Hartmut W 2008J Clin Invest2008,118,10:1
8Finite element analysis of the membrane used in a novel bioMEMS显示文摘SANG S B HARTMUT W 2009J Biomimetics Biomater Tissue Eng2009,3,:1
9Intrauterine growth restriction: definition and etiology 显示文摘Hartmut A W 1998Horm Res1998,49,:1
10Lipoxygenase-dependent degradation of storage lipids显示文摘Ivo F Hartmut K Claus W 2001Trends in Plant Science2001,6,6:1
11Cardiac sympathetic innervation in patients with idiopathic right ventricular outflow tract tachycardia 显示文摘Michael S Hartmut L Thomas W 1998J Am Coll Cardiol1998,32,:1
12Principles of contact lens tonometry显示文摘Peter W Dekker Yves C A Robert Hartmut Kanngiesser Peter Pirani Beatrix Entenmann 1998International Ophthalmology1998,,2:1
13Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee显示文摘David W Dempster Juliet E Compston Marc K Drezner Francis H Glorieux John A Kanis Hartmut Malluche Pierre J Meunier Susan M Ott Robert R Recker A Michael Parfitt 2012J Bone Miner Res2012,,1:1
14High force measurement sensitivity with fiber Bragg gratings fabricated in uniform-waist fiber tapers显示文摘TORSTEN W SVEN B HARTMUT B 2011Measurement Science and Technology2011,22,07:1
15Adsorption of PCDD/F on MWI fly ash显示文摘HARTMUT M BAUMANN W BECKER B 2001Chemosphere2001,42,57:1
16查看详情显示文摘J udit C Hartmut F Gijsbertus D W 0,,:1
17Quality control of beer using high-resolution nuclear magnetic resonance spectroscopy and multivariate analysis显示文摘Dirk W Lachenmeier Willi Frank Eberhard Humpfer Hartmut Sch?fer Silke Keller Monika M?rtter Manfred Spraul 2005European Food Research and Technology2005,,2:1
18Brainlab vector vision neuronavigation system: technology and clinical experiences in 131 cases 显示文摘HARTMUT KGFINOS J G FITZPATRICK B C DARIUS C W 1999Neurosurgery1999,44,1:1
19Wind effects on leaf mor- phology for the mangrove Conocrpus erecta at an oceanic island from the Mexican Pacific Ocean显示文摘ERICK D L HARTMUT S W 2006Revista Chilena De Historia Natural2006,79,4:1
20Liquid crystal display as spatial light modulator for diffractive optical elements and the reconstruction of digital holograms显示文摘GUNTHER W SVEN K HARTMUT G 2001Proceedings of SPIE2001,4596,:1
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