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| 1 | Human bronchial epithelial cell injuries induced by fine particulate matter from sandstorm and non-sandstorm periods:Association with particle constituents显示文摘Epidemiological studies have demonstrated the exacerbation of respiratory diseases following sandstorm-derived particulate matter(PM) exposure.The presence of anthropogenic and biological agents on the sandstorm PM and the escalation of PM < 2.5 μm(PM2.5)pollution in China have led to serious concerns regarding the health effects of PM2.5during Asian sandstorms.We investigated how changes in PM2.5composition,as the weather transitioned towards a sandstorm,affected human airway epithelial cells.Six PM2.5samples covering two sandstorm events and their respective background and transition periods were collected in Baotou,an industrial city near the Gobi Desert in China.PM samples from all three periods had mild cytotoxicity in human bronchial epithelial cell line BEAS-2B,which was positively correlated with the contents of polycyclic aromatic hydrocarbons and several metals.All PM samples potently increased the release of interleukin-6(IL-6) and interleukin-8(IL-8).Endotoxin in all samples contributed significantly to the IL-6 response,with only a minor effect on IL-8.Cr was positively correlated with both IL-6 and IL-8 release,while Si was only associated with the increase of IL-6.Our study suggests that local agricultural and industrial surroundings in addition to the sandstorm play important roles in the respiratory effects of sandstorm-derived PM. | Bin Wang Ning Li Furong Deng Nicholas Buglak George Park Shu Su Aiguo Ren Guofeng Shen Shu Tao Xinbiao Guo | 2016 | Journal of Environmental Sciences2016，28，9： | 9 |
| 2 | Association of emergency room visits for respiratory diseases with sources of ambient PM2.5显示文摘Previous studies have reported associations of short-term exposure to different sources of ambient fine particulate matter(PM2.5)and increased mortality or hospitalizations for respiratory diseases.Few studies,however,have focused on the short-term effects of source-specific PM2.5 on emergency room visits(ERVs)of respiratory diseases.Source apportionment for PM2.5 was performed with Positive Matrix Factorization(PMF)and generalized additive model was applied to estimate associations between source-specific PM2.5 and respiratory disease ERVs.The association of PM2.5 and total respiratory ERVs was found on lag4(RR=1.011,95%CI:1.002,1.020)per interquartile range(76μg/m3)increase.We found PM2.5 to be significantly associated with asthma,bronchitis and chronic obstructive pulmonary disease(COPD)ERVs,with the strongest effects on lag5(RR=1.072,95%CI:1.024,1.119),lag4(RR=1.104,95%CI:1.032,1.176)and lag3(RR=1.091,95%CI:1.047,1.135),respectively.The estimated effects of PM2.5 changed little after adjusting for different air pollutants.Six primary PM2.5 sources were identified using PMF analysis,including dust/soil(6.7%),industry emission(4.5%),secondary aerosols(30.3%),metal processing(3.2%),coal combustion(37.5%)and traffic-related source(17.8%).Some of the sources were identified to have effects on ERVs of total respiratory diseases(dust/soil,secondary aerosols,metal processing,coal combustion and traffic-related source),bronchitis ERVs(dust/soil)and COPD ERVs(traffic-related source,industry emission and secondary aerosols).Different sources of PM2.5 contribute to increased risk of respiratory ERVs to different extents,which may provide potential implications for the decision making of air quality related policies,rational emission control and public health welfare. | Rui Chi Hongyu Li Qian Wang Qiangrong Zhai Daidai Wang Meng Wu Qichen Liu Shaowei Wu Qingbian Ma Furong Deng Xinbiao Guo | 2019 | Journal of Environmental Sciences2019，31，12： | 8 |
| 3 | Association of Heart Rate Variability in Taxi Drivers with Marked Changes in Particulate Air Pollution in Beijing in 2008显示文摘 | Wu Shaowei Deng Furong Niu Jie Huang Qinsheng Liu Youcheng Guo Xinbiao | 2010 | Environmental Health Perspectives2010，，1： | 1 |
| 4 | Cardiorespiratory Effects of Indoor Ozone Exposure Associated with Changes in Metabolic Profiles among Children:A Repeated-Measure Panel Study显示文摘Ozone is one of the major gaseous pollutants associated with short-term adverse cardiopulmonary effects,even at concentrations below the current indoor air quality limits.However,the underlying biological mechanisms of cardiorespiratory changes with exposure to ozone remain unclear.To further explore molecular linkages between indoor ozone exposure and relevant cardiorespiratory effects,a repeated-measure panel study including 46 schoolchildren was conducted and real-time exposure measurements including ozone were performed inside classrooms every weekday during the study period.Repeated health measurements and urine sample collection were conducted in each participant.Ultra-high-performance liquid chromatography/tandem mass spectrometry and meet-in-metabolite approach were used in metabolomics analysis.Methods including mixed-effect models were adopted to identify metabolites associated with ozone exposure or health indices.Nine metabolites were found to be associated with ozone after mixed-effect model analysis,which are mainly involved in amino acid and bile acid metabolism.Boys may have a greater decrease in bile acid and RNA related metabolites.Four of the nine ozone-related metabolites were also associated with cardiorespiratory function indices.Furthermore,26.67%of the positive association between ozone and heart rate was mediated by cholestane-3,7,12,25-tetrol-3-glucuronide.Exposure to ozone below the current indoor standards was associated with the deteriorated cardiovascular function by disturbing bile acid and endogenous nitric oxide-related oxidation and inflammation,and associated with the exacerbated airway inflammation by reducing GPx-related anti-oxidation.The results provide metabolic evidence of the cardiorespiratory effects of indoor ozone exposure.Indoor ozone pollution should be controlled further,and more attention should be paid to preventing its adverse health effects,especially in children. | Shan Liu Qingyu Huang Xi Zhang Wei Dong Wenlou Zhang Shaowei Wu Di Yang Bingru Nan Jie Zhang Heqing Shen Xinbiao Guo Furong Deng | 2021 | The Innovation2021，2，1： | 1 |
| 5 | Association of systemic inflammation with marked changes in particulate air pollution in Beijing in 2008显示文摘 | Xiaohua Xu Furong Deng Xinbiao Guo Peng Lv Mianhua Zhong Cuiqing Liu Aixia Wang Kevin Tzan Silis Y. Jiang Morton Lippmann Sanjay Rajagopalan Qingshan Qu Lung-Chi Chen Qinghua Sun | 2012 | Toxicology Letters2012，，2： | 1 |
| 6 | Association of systemic inflammation with marked changes in particulate air pollution in Beijing in 2008显示文摘 | Xiaohua Xu Furong Deng Xinbiao Guo Peng Lv Mianhua Zhong Cuiqing Liu Aixia Wang Kevin Tzan Silis Y. Jiang Morton Lippmann Sanjay Rajagopalan Qingshan Qu Lung-Chi Chen Qinghua Sun | 2012 | Toxicology Letters2012，，2： | 1 |
| 7 | Effects of fine particulate on heart rate variability in Beijing: a panel study of healthy elderly subjects显示文摘 | Xiaofeng Jia Xiaoming Song Masayuki Shima Kenji Tamura Furong Deng Xinbiao Guo | 2012 | International Archives of Occupational and Environmental Health2012，，1： | 1 |
| 8 | Effects of dust storm PM 2.5 on cell proliferation and cell cycle in human lung fibroblasts显示文摘 | Furong Deng Xinbiao Guo Hong Liu Xin Fang Minjuan Yang Wei Chen | 2007 | Toxicology in Vitro2007，，4： | 1 |
| 9 | Irradiation detection of oilseed crops by electron spin resonance显示文摘 | FU Junjie ZHAO Xiaojun XU Furong FENG Duhua WANG Qing DENG Li | 2013 | Nuclear Science and Techniques2013，24，B12： | 1 |
| 10 | Exposures to PM 2.5 components and heart rate variability in taxi drivers around the Beijing 2008 Olympic Games显示文摘 | Shaowei Wu Furong Deng Jie Niu Qinsheng Huang Youcheng Liu Xinbiao Guo | 2011 | Science of the Total Environment2011，，13： | 1 |
| 11 | Time effects of rice straw and engineered bacteria on reduction of exogenous Cu mobility in three typical Chinese soils显示文摘Globally,copper(Cu)accumulation in soils is a major environmental concern.Agricultural organic waste and some bacterial species can readily absorb metals in an eco-friendly manner,and thus are commonly used in metal-contaminated soil remediation.This study investigates the change in Cu fractions during the aging process and the time effects of rice straw(RS)and engineered bacteria(EB)(Pseudomonas putida X4/pIME)on reduction of Cu mobility.Three typical Chinese soils(red,cinnamon,and black soils)were incubated with RS or RS+EB in the presence of exogenous Cu for 24 months.The soil physicochemical properties,reactive soil components,Cu fractions,and Cu mobility were determined over time.The Cu mobility factor(MF)values were the lowest in the black soil(6.4-9.2)because of its high organic carbon and clay contents.The additions of both RS and RS+EB accelerated Cu stabilization during the aging process in all three soils.The Cu MF values decreased with time during the initial 20 months;however,the MF values increased thereafter in all soils,which might be due to the reduction of humic substances and amorphous iron oxides and the increase in iron oxides complexed on the organic matter.The reduction rates of Cu MF were similar after 16,24,and more than 24 months in the red,cinnamon,and black soils,respectively,indicating that RS and RS+EB could limit Cu mobility at different times in various soils.The RS treatment showed the greatest efficiency in reducing Cu mobility in the red,cinnamon,and black soils after 12,12,and 8 months of incubation,respectively.The RS+EB treatment was more efficient than the RS treatment in the red soil during the initial 8 months of the incubation period.Our study provides theoretical support for Cu risk assessments and RS supplementation for Cu remediation in different soils. | Hanzhi SHI Dian WEN Yongdong HUANG Shoujun XU Tenghaobo DENG Furong LI Zhichao WU Xu WANG Peihua ZHAO Fuhua WANG Ruiying DU | 2022 | Pedosphere2022，32，5： | 0 |
| 12 | Tumor neutrophils ferroptosis:a targetable immunosuppressive mechanism for cancer immunotherapy显示文摘In a recent study published in Nature,Kim et al.demonstrated that ferroptosis of polymorphonuclear myeloid-derived suppressor cells(PMN-MDSCs)causes immune suppression in cancer,1 highlighting ferroptosis inhibition as a targetable therapeutic strategy for cancer immunotherapy. | Songtao Du Furong Zeng Guangtong Deng | 2023 | Signal Transduction and Targeted Therapy2023，8，3： | 0 |
| 13 | Co-Exposure to Multiple Pollutants and Its Cardiovascular Effects in a Subway System-Beijing Municipality,China,2017显示文摘Summary What is already known on this topic?With rapid urbanization,traffic-related air pollution has become a global concern.However,its association with cardiovascular health has not been fully elucidated.What is added by this report?This study provided novel evidence of the joint cardiovascular effect of multiple pollutants in subway cabins,further identified two pollutants that played dominant roles,and validated the effectiveness of targeted interventions. | Wenlou Zhang Xuan Yang Xu Jia Wei Dong Hongyu Li Lu Pan Jiao Shan Shaowei Wu Xinbiao Guo Furong Deng | 2021 | China CDC weekly2021，3，45： | 0 |
| 14 | Storage-Reduction of NO_(x)over Combined Catalysts of Pt/Ba/Al_(2)O_(3)-Mn/Ba/Al_(2)O_(3):Carbon Monoxide as Reductant显示文摘由一氧化碳的 NOX 的存储减小在 Mn/Ba/Al2O3-Pt/Ba/Al2O3 的联合催化剂上被调查。以不同方法的 Mn/Ba/Al2O3 和 Pt/Ba/Al2O3 催化剂的联合证明优秀 NOX 存储减小性能和磅的内容能被 50% 减少。到 lPt/15Ba/Al2Oa 的 5Mn/15Ba/Al2Oa 的增加能不仅改进它的存储能力,而且因而提高 NOX 变换。在联合催化剂上的 NOx 变换(联合催化剂我和 II ) 在动态瘦富人的灼伤条件下面被增加,最大的 NOX 变换从 69.4% 增加了到分别地 78.8% 和 75.7% 超过二联合催化剂。给词调音:氧化氮;存储减小;瘦灼伤; | Sha Deng Xuehui Li Jianhua Xiao Furong Wang Lefu Wang | 2007 | Journal of Natural Gas Chemistry2007，16，2： | 0 |
| 15 | 血压变化和空气污染微粒的化学成分显示文摘[背景]血压升高与颗粒物(PM)空气污染相关,但是与PM化学成分的关联尚不明确。[目的]通过对一组39名大学生进行460次反复访查,探讨血压与不同化学成分的细颗粒物(PM2.5)之间的关联。 | Shaowei Wu Furong Deng Jing Huang Hongyi Wang Masayuki Shima Xin Wang Yu Qin Chanjuan Zheng Hongying Wei Yu Hao Haibo Lv Xiuling Lu Xinbiao Guo | 2013 | 环境与职业医学2013，30，4： | 0 |
| 16 | Association between exposure to air pollutants and sleep parameters in chronic obstructive pulmonary disease patients with or without obstructive sleep apnea显示文摘To the Editor:Air pollution is.a rapidly developing environmental problem worldwide.A large number of studies have indicated that ambient air pollutants have effects on mortality and morbidity of respiratory diseases.Remarkably,paramount attention should be paid to the impact on respiratory diseases associated with air pollution from a public health standpoint. | Junyi Wang Wanlu Sun Wanzhou Wang Wenlou Zhang Ying Wang Yongwei Huang Jianli Wang Liqiang Zhang Yahong Chen Xinbiao Guo Furong Deng | 2022 | Chinese Medical Journal2022，135，16： | 0 |
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