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| 1 | International consensus statement on robotic hepatectomy surgery in 2018显示文摘The robotic surgical system has been applied in liver surgery. However,controversies concerns exist regarding a variety of factors including the safety,feasibility, efficacy, and cost-effectiveness of robotic surgery. To promote the development of robotic hepatectomy, this study aimed to evaluate the current status of robotic hepatectomy and provide sixty experts' consensus and recommendations to promote its development. Based on the World Health Organization Handbook for Guideline Development, a Consensus Steering Group and a Consensus Development Group were established to determine the topics, prepare evidence-based documents, and generate recommendations. The GRADE Grid method and Delphi vote were used to formulate the recommendations. A total of 22 topics were prepared analyzed and widely discussed during the 4 meetings. Based on the published articles and expert panel opinion, 7 recommendations were generated by the GRADE method using an evidence-based method, which focused on the safety, feasibility, indication,techniques and cost-effectiveness of hepatectomy. Given that the current evidences were low to very low as evaluated by the GRADE method, further randomized-controlled trials are needed in the future to validate these recommendations. | Rong Liu Go Wakabayashi Hong-Jin Kim Gi-Hong Choi Anusak Yiengpruksawan Yuman Fong Jin He Ugo Boggi Roberto I Troisi Mikhail Efanov Daniel Azoulay Fabrizio Panaro Patrick Pessaux Xiao-Ying Wang Ji-Ye Zhu Shao-Geng Zhang Chuan-Dong Sun Zheng Wu Kai-Shan Tao Ke-Hu Yang Jia Fan Xiao-Ping Chen | 2019 | World Journal of Gastroenterology2019，25，12： | 23 |
| 2 | First quarter century of laparoscopic liver resection显示文摘The beginnings of laparoscopic liver resection(LLR)were at the start of the 1990s,with the initial reports being published in 1991 and 1992.These were followed by reports of left lateral sectionectomy in 1996.In the years following,the procedures of LLR were expanded to hemi-hepatectomy,sectionectomy,segmentectomy and partial resection of posterosuperior segments,as well as the parenchymal preserving limited anatomical resection and modified anatomical(extended and/or combining limited)resection procedures.This expanded range of LLR procedures,mimicking the expansion of open liver resection in the past,was related to advances in both technology(instrumentation)and technical skill with conceptual changes.During this period of remarkable development,two international consensus conferences were held(2008 in Louisville,KY,United States,and 2014 in Morioka,Japan),providing up-to-date summarizations of the status and perspective of LLR.The advantages of LLR have become clear,and include reduced intraoperative bleeding,shorter hospital stay,and-especially for cirrhotic patients-lower incidence of complications(e.g.,postoperative ascites and liver failure).In this paper,we review and discuss the developments of LLR in operative procedures(extent and style of liver resections)during the first quarter century since its inception,from the aspect of relationships with technological/technical developments with conceptual changes. | Zenichi Morise Go Wakabayashi | 2017 | World Journal of Gastroenterology2017，23，20： | 16 |
| 3 | Coexistence of esophageal superficial carcinoma and multiple leiomyomas:A case report显示文摘平滑肌瘤是食管的最普通的良性瘤。他们通常作为单个损害或作为二或三个小瘤发生。仅仅包括超过 10 个小瘤的食道的多重平滑肌瘤的二个案例以前被报导了。而且,有食道的有鳞的房间癌覆闷死粘膜下层肿瘤的很少报告。我们描述作为有表面的食道的癌症与二或三个平滑肌瘤小瘤共存被诊断的一个 71 岁的人。在外科期间, 10 或一直不外科手术前地是明显的更多的小瘤在整个食管在粘膜下层和肌层是摸得出的。当食道的癌症的内部转移被怀疑,我们认为另外的淋巴是腺切除术,但是因为病人的严重血缺氧,不得不排除这种选择。显微镜检查表明所有小瘤是平滑肌瘤(20 损害,在直径的多达 3 厘米) ,并且癌房间的那侵略被限制到粘膜下层层 overlying 一个相对大的平滑肌瘤。这是与众多的独居的平滑肌瘤共存的表面的食道的癌症的第一份报告。多重极小的平滑肌瘤经常也在一个癌损害罐头的底作为内部转移,和一个平滑肌瘤被误诊作为肿瘤侵略被误诊。现在的案例证明那精确诊断与共存为病人的管理被要求表面的食道的癌症和多重平滑肌瘤。 | Takeshi Iwaya Chihaya Maesawa Noriyuki Uesugi Toshimoto Kimura Kenichiro Ikeda Yusuke Kimura Shingo Mitomo Kaoru Ishida Nobuhiro Sato Go Wakabayashi | 2006 | World Journal of Gastroenterology2006，12，28： | 7 |
| 4 | Laparoscopic Major Hepatectomy: A Systematic Literature Review and Comparison of 3 Techniques显示文摘 | Niang-Cheng Lin Hiroyuki Nitta Go Wakabayashi | 2013 | Annals of Surgery2013，，2： | 4 |
| 5 | High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis显示文摘AIM: An increase in bile ductular structures is observed in diverse human liver diseases, especially in primary biliary cirrhosis (PBC). These structures harbor the progenitor cell component of the liver. Caveolins are cholesterol-binding proteins involved in the regulation of several intracellular processes including cholesterol transport. This study aims to examine the role of caveolin in PBC.METHODS: Immunohistochemical and Western blottingstudies were performed on human liver specimens obtained from patients with PBC and normal liver samples. The expression of caveolin (CAV)-1 and -2 was determined using specific antibodies.RESULTS: In normal liver, scanty immunostaining for CAV1 and -2 was observed in bile ductules. In PBC liver samples, the expression levels of CAV-1 and -2 were increased on proliferating bile ductules especially in stage 3 cases, but was sparse on interlobular bile duct in stage 1 specimens. Especially, the regenerating bile ductules at the interface of portal tracts and necrotic areas were immunostained intensely for CAV-1 and -2. These phenomena were confirmed by Western blot.CONCLUSION: The present results demonstrate increased expression of caveolins in proliferating bile ductules in PBC, which may be related to the homeostasis of cholesterol transport in regenerating bile ductules in PBC liver. | Hiroaki Yokomori Masaya Oda Go Wakabayashi Masaki Kitajima Kazunori Yoshimura Masahiko Nomura Toshifumi Hibi | 2005 | World Journal of Gastroenterology2005，11，24： | 4 |
| 6 | Expression of adhesion molecules on mature cholangiocytes in canal of Hering and bile ductules in wedge biopsy samples of primary biliary cirrhosis显示文摘AIM: To examine the expression of intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1) expression on canals of Hering (CoH)and bile ductules associated with the autoimmune process of bile duct destruction in primary biliary cirrhosis (PBC).METHODS: Ten wedged liver biopsies of PBC (five cases each of stages 2 and 3) were studied. The liver specimens were processed for transmission electron microscopy.Immunohistochemistry was performed using anti-ICAM-1 and anti-LFA-1 mouse mAbs. In situ hybridization was done to examine the messenger RNA expression of ICAM-1 in formalin-fixed, paraffin-embedded sections using peptide nucleic acid probes and the catalyzed signal amplification (CSA) technique. Immunogold-silver staining for electron microscopy was performed using anti-ICAM and anti-LFA-1 mouse mAbs. The immunogold particles on epithelial cells of bile ductules and cholangiocytes of CoH cells were counted and analyzed semi-quantitatively.Western blotting was performed to confirm ICAM-1 protein expression.RESULTS: In liver tissues of PBC patients, immunohistochemistry showed aberrant ICAM-1 expression on the plasma membrane of epithelial cells lining bile ductules,and also on mature cholangiocytes but not on hepatocytes in CoH. LFA-1-positive lymphocytes were closely associated with epithelial cells in bile ductules. ICAM-1 expression at protein level was confirmed by Western blot. In situ hybridization demonstrated ICAM-1 mRNA expression in bile ductules and LFA-1 mRNA in lymphocytes infiltrating the bile ductules. By immunoelectron microscopy, ICAM-1 was demonstrated on the basal surface of epithelial cells in bile ductules and on the luminal surfaces of cholangiocytes in damaged CoH. Cells with intermediate morphology resembling progenitor cells in CoH were not labeled with ICAM-1 and LFA-1.CONCLUSION: De novo expression of ICAM-1 both on mature cholangiocytes in CoH and epithelial cells in bile ductules in PBC implies that lymphocyte-induced destruction through adhesion by ICAM-1 and binding of LFA-1-expressing activated lymphocytes takes place not only in bile ductules but also in the CoH. | Hiroaki Yokomori Masaya Oda Mariko Ogi Go Wakabayashi Shigeyuki Kawachi Kazunori Yoshimura Toshihiro Nagai Masaki Kitajima Masahiko Nomura Toshifumi Hibi | 2005 | World Journal of Gastroenterology2005，11，28： | 4 |
| 7 | Evaluation of stapler hepatectomy during a laparoscopic liver resection显示文摘 | Joseph F. Buell Brice Gayet Ho‐Seong Han Go Wakabayashi Ki‐Hun Kim Giulio Belli Robert Cannon Bob Saggi Hiro Keneko Alan Koffron Guy Brock Ibrahim Dagher | 2013 | HPB2013，，11： | 3 |
| 8 | Clinical significance of the expression of long non-coding RNA HOTAIRin primary hepatocellular carcinoma显示文摘 | Masahisa Ishibashi Ryunosuke Kogo Kohei Shibata Genta Sawada Yusuke Takahashi Junji Kurashige Sayuri Akiyoshi Shin Sasaki Takeshi Iwaya Tomoya Sudo Keishi Sugimachi Koshi Mimori Go Wakabayashi Masaki Mori | 2013 | Oncology Reports2013，，3： | 2 |
| 9 | Impact of three-dimensional analysis of multidetector row computed tomography cholangioportography in operative planning for hilar cholangiocarcinoma显示文摘 | Ryoko Sasaki Tadashi Kondo Tatsuya Oda Soichiro Murata Go Wakabayashi Nobuhiro Ohkohchi | 2011 | The American Journal of Surgery2011，，4： | 2 |
| 10 | The International Position on Laparoscopic Liver Surgery: The Louisville Statement, 2008显示文摘 | Joseph F. Buell Daniel Cherqui David A. Geller Nicholas O’Rourke David Iannitti Ibrahim Dagher Alan J. Koffron Mark Thomas Brice Gayet Ho Seong Han Go Wakabayashi Giulio Belli Hironori Kaneko Chen-Guo Ker Olivier Scatton Alexis Laurent Eddie K. Abdalla Pr | 2009 | Annals of Surgery2009，，3： | 2 |
| 11 | International experts consensus guidelines on robotic liver resection in 2023显示文摘The robotic liver resection(RLR)has been increasingly applied in recent years and its benefits shown in some aspects owing to the technical advancement of robotic surgical system,however,controversies still exist.Based on the foundation of the previous consensus statement,this new consensus document aimed to update clinical recommendations and provide guidance to improve the outcomes of RLR clinical practice.The guideline steering group and guideline expert group were formed by 29 international experts of liver surgery and evidence-based medicine(EBM).Relevant literature was reviewed and analyzed by the evidence evaluation group.According to the WHO Handbook for Guideline Development,the Guidance Principles of Development and Amendment of the Guidelines for Clinical Diagnosis and Treatment in China 2022,a total of 14 recommendations were generated.Among them were 8 recommendations formulated by the GRADE method,and the remaining 6 recommendations were formulated based on literature review and experts’opinion due to insufficient EBM results.This international experts consensus guideline offered guidance for the safe and effective clinical practice and the research direction of RLR in future. | Rong Liu Mohammed Abu Hilal Go Wakabayashi Ho-Seong Han Chinnusamy Palanivelu Ugo Boggi Thilo Hackert Hong-Jin Kim Xiao-Ying Wang Ming-Gen Hu Gi Hong Choi Fabrizio Panaro Jin He Mikhail Efanov Xiao-Yu Yin Roland S Croner Yu-Man Fong Ji-Ye Zhu Zheng Wu Chuan-Dong Sun Jae Hoon Lee Marco V Marino Iyer Shridhar Ganpati Peng Zhu Zi-Zheng Wang Ke-Hu Yang Jia Fan Xiao-Ping Chen Wan Yee Lau | 2023 | World Journal of Gastroenterology2023，29，32： | 2 |
| 12 | The International Position on Laparoscopic Liver Surgery: The Louisville Statement, 2008显示文摘 | Joseph F. Buell Daniel Cherqui David A. Geller Nicholas O'Rourke David Iannitti Ibrahim Dagher Alan J. Koffron Mark Thomas Brice Gayet Ho Seong Han Go Wakabayashi Giulio Belli Hironori Kaneko Chen-Guo Ker Olivier Scatton Alexis Laurent Eddie K. Abdalla Pr | 2009 | Annals of Surgery2009，，3： | 2 |
| 13 | Diagnosis and Treatment of a Gastric Hamartomatous Inverted Polyp: Report of a Case显示文摘 | Masahiko Aoki Masashi Yoshida Yoshiro Saikawa Yoshihide Otani Tetsuro Kubota Koichiro Kumai Go Wakabayashi Tai Omori Makio Mukai Masaki Kitajima | 2004 | Surgery Today2004，，6： | 2 |
| 14 | Systematic review of robotic liver resection显示文摘 | Cheng-Maw Ho Go Wakabayashi Hiroyuki Nitta Naoko Ito Yasushi Hasegawa Takeshi Takahara | 2013 | Surgical Endoscopy2013，，3： | 1 |
| 15 | Laparoscopy-Assisted Major Liver Resections Employing A Hanging Technique: The Original Procedure显示文摘 | Hiroyuki Nitta Akira Sasaki Tomohiro Fujita Hidenori Itabashi Koichi Hoshikawa Takeshi Takahara Masahiro Takahashi Satoshi Nishizuka Go Wakabayashi | 2010 | Annals of Surgery2010，，3： | 1 |
| 16 | Single-port Versus Multiport Laparoscopic Cholecystectomy: A Prospective Randomized Clinical Trial显示文摘 | Akira Sasaki Masaaki Ogawa Chihiro Tono Shin Obara Nobuyuki Hosoi Go Wakabayashi | 2012 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2012，，5： | 1 |
| 17 | Status of endoscopic liver surgery in Japan: a questionnaire survey conducted by the Japanese Endoscopic Liver Surgery Study Group显示文摘 | Masaru Tsuchiya Yuichiro Otsuka Akira Tamura Hiroyuki Nitta Akira Sasaki Go Wakabayashi Hironori Kaneko | 2009 | Journal of Hepato - Biliary - Pancreatic Surgery2009，，4： | 1 |
| 18 | Significance of Ductal Margin Status in Patients Undergoing Surgical Resection for Extrahepatic Cholangiocarcinoma显示文摘 | Ryoko Sasaki Yuichiro Takeda Osamu Funato Hiroyuki Nitta Hidenobu Kawamura Noriyuki Uesugi Tamotsu Sugai Go Wakabayashi Nobuhiro Ohkohchi | 2007 | World Journal of Surgery2007，，9： | 1 |
| 19 | Gallbladder carcinoma with osteoclast-like giant cells显示文摘 | Tomotaka Akatsu Kaori Kameyama Shigeyuki Kawachi Minoru Tanabe Koichi Aiura Go Wakabayashi Masakazu Ueda Motohide Shimazu Masaki Kitajima | 2006 | Journal of Gastroenterology2006，，1： | 1 |
| 20 | Totally laparoscopic total gastrectomy for gastric cancer: Literature review and comparison of the procedure of esophagojejunostomy显示文摘 | Akira Umemura Keisuke Koeda Akira Sasaki Hisataka Fujiwara Yusuke Kimura Takeshi Iwaya Yuji Akiyama Go Wakabayashi | 2014 | Asian Journal of Surgery2014，，： | 1 |
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