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| 1 | Altered blood-brain barrier permeability in rats with prehepatic portal hypertension turns to normal when portal pressure is lowered显示文摘AIM: To study the blood-brain barrier integrity in prehe-patic portal hypertensive rats induced by partial portal vein ligation, at 14 and 40 d after ligation when portal pressure is spontaneously normalized. METHODS: Adult male Wistar rats were divided into four groups: GroupⅠ: Sham14d, sham operated; GroupⅡ: PH14d, portal vein stenosis; (both groups were used 14 days after surgery); GroupⅢ: Sham40d, Sham operated and GroupⅣ: PH40d Portal vein stenosis (GroupsⅡandⅣused 40 d after surgery). Plasma ammonia, plasma and cerebrospinal fluid protein and liver enzymes concentrations were determined. Trypan and Evans blue dyes, systemically injected, were investigated in hippocampus to study blood-brain barrier integrity. Portal pressure was periodically recorded. RESULTS: Forty days after stricture, portal pressure was normalized, plasma ammonia was moderately high, and both dyes were absent in central nervous system parenchyma. All other parameters were reestablished. When portal pressure was normalized and ammonia level was lowered, but not normal, the altered integrity of blood-brain barrier becomes reestablished. CONCLUSION: The impairment of blood-brain barrier and subsequent normalization could be a mechanism involved in hepatic encephalopathy reversibility, Hemo-dynamic changes and ammonia could trigger blood-brain barrier alterations and its reestablishment. | Francisco Eizayaga Camila Scorticati Juan P Prestifilippo Salvador Romay Maria A Fernandez José L Castro Abraham Lemberg Juan C Perazzo | 2006 | World Journal of Gastroenterology2006，12，9： | 3 |
| 2 | 烧结条件与组成对含Cr粉末冶金钢力学性能的影响显示文摘对先进铁基粉末冶金材料的期望,已导致开发了更接近模拟锻钢组成的合金。像Cr等传统锻钢合金化元素,已用于提高力学性能与淬透性,而且成本可行。过去在粉末冶金中避免用铬是因为与氧相关的问题,但现在较新的合金系都含有这种元素。尽管这些合金可提供良好的力学性能与生产总成本可行,但这些合金的适当烧结仍是关键性问题。将介绍烧结条件与组成对含Cr粉末冶金钢的力学性能与显微结构的影响。 | Francisco Castro Shandra Sainz Bruce Lindsley W.Brian James 亓家钟 | 2011 | 粉末冶金技术2011，29，4： | 3 |
| 3 | Transient elastography to rule out esophageal varices and portal hypertensive gastropathy in HIV-infected individuals with liver cirrhosis显示文摘 | Maria L. Montes Ramirez Jose F. Pascual-Pareja Matilde Sánchez-Conde Jose I. Bernardino De la Serna Francisco X. Zamora Vargas Pilar Miralles Juan M. Castro Margarita Ramírez Isabel Gutierrez Juan Gonzalez-García Juan Berenguer Jose R. Arribas López | 2012 | AIDS2012，，14： | 1 |
| 4 | Integrated risk management: a Petrobras application in offshore well construction safety to minimize critical emergency disconnections显示文摘In order to avoid mistakes and to save a great deal of time in analysis, an innovative methodology was developed that can analyze the well operations and rig characteristics involved to define the best emergency disconnect sequence(EDS)available. A solution was developed based on the characteristics of the rigs and blowout preventers(BOPs), and six variables were considered that directly affect the choice of EDS. All possible combinations of 64 scenarios were analyzed,and the priority of choice of the EDS was defined empirically. This paper presents an approach to EDS risk management and examples of exposure time(time without riser safety margin and shear capability) for the same well, which can be lowered from 13% to 0.1%. The impact of this reduction is related to the ability of the BOP to cut some of the heavy casings, in addition to improved availability of EDS modes. This implementation opened up many possibilities for the performance of risk exposure analysis, enabling comparison of several BOP configurations of contracted rigs and selection of the best options. This innovative approach allowed a better management of the rig schedules, prioritizing safety aspects and making it possible to allocate the fleet in a systematic way. | Claudio Benevenuto de Campos Lima Pedro Esteves Aranha Jose Francisco Tebaldi de Castro Gilson Brito Alves Lima Augusto Borella Hougaz Felipe de Souza Terra | 2018 | Petroleum Science2018，15，2： | 1 |
| 5 | Reliability improvement of the Guri hydroelectric power plant computer control system AGC and AVC显示文摘 | Francisco Castro Gabriel Llort Michele Pescina | 1992 | IEEE Trans on Power Systems1992，7，3： | 1 |
| 6 | Urban wind energy exploitation systems:Behaviour under multidirectional flowconditionsOpportunities and challenges显示文摘 | Francisco Toja Silva Antonio Colmenar Santos Manuel Castro Gil | 2013 | Renewable and Sustainable Energy Reviews2013，24，： | 1 |
| 7 | Cytokine expression in porcine lungs experimentally infected with Mycoplasma hyopneumoniae显示文摘 | Héctor Lorenzo óscar Quesada Patricia Assun?ao Ayoze Castro Francisco Rodríguez | 2005 | Veterinary Immunology and Immunopathology2005，，3： | 1 |
| 8 | Continuous and Cyclic Oxidation of T91 Ferritic Steel under Steam显示文摘 | Tomas GomezAcebo Francisco Castro | 2004 | Corrosion Science2004，，46： | 1 |
| 9 | The Investment Develo-pment Path: The Case of Portugal显示文摘 | Buckley Peter J Castro Francisco B | 1998 | Transnational Corporations1998，7，1： | 1 |
| 10 | Photoelectrocatalytic oxidation of remazol turquoise blue and toxicological assessment of its oxidation products 显示文摘 | Marli E Osugi Gisela A Umbuzeiro Francisco J V De Castro | 2006 | Joumal of Hazardous Materials2006，137，2： | 1 |
| 11 | Molecular behavior of ionic and nonionic surfactants in saline medium显示文摘 | Francisco Klebson G. Santos Eduardo L. Barros Neto Maria Carlenise P.A. Moura Tereza N. Castro Dantas Afonso A. Dantas Neto | 2008 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2008，，1： | 1 |
| 12 | Low viscosity hydrogel of guar gum:preparation and physicochemical characterization显示文摘 | Cunha Rondinelle R Castro Francisco A C Rocha | 2005 | Biological Macromolecules2005，37，： | 1 |
| 13 | Evaluation and determination of chloride in crude oil based on the counterions Na, Ca, Mg, Sr and Fe, quantified via ICP-OES in the crude oil aqueous extract显示文摘 | Murilo de Oliveira Souza Maria Aparecida Ribeiro Maria Tereza Weitzel Dias Carneiro Geisamanda Pedrini Brand?o Athayde Eustáquio Vinícius Ribeiro de Castro Francisco Luan Fonseca da Silva Wladiana Oliveira Matos Rafael de Queiroz Ferreira | 2015 | Fuel2015，，： | 1 |
| 14 | Continuous and Cyclic Oxidation of T91 Ferritic Steel Under Steam显示文摘 | Tomas Gomez-Acebo Francisco Castro | 2004 | Corrosion Science2004，，46： | 1 |
| 15 | Relevance of insulin-like growth factor 1 receptor gene expression as a prognostic factor in non-small-cell lung cancer显示文摘 | M. Teresa Agulló-Ortu?o C. Vanesa Díaz-García Alba Agudo-López Carlos Pérez Ana Cortijo Luis Paz-Ares Fernando López-Ríos Francisco Pozo Javier de Castro Hernán Cortés-Funes José A. López Martín | 2015 | Journal of Cancer Research and Clinical Oncology2015，，： | 1 |
| 16 | Recycling of solid waste rich in organic nitrogen from leather industry:Mineral nutrition of rice plants 显示文摘 | Nogueira Francisco G E Castro lsabda A Bastos Ana R R | 2011 | Journal of Hazardous Materials2011，186，： | 1 |
| 17 | Three dimensional model of the interception of light by a canopy显示文摘 | Castro Francisco de Fetcher Ned | 1998 | Agric For Meteorol1998，90，： | 1 |
| 18 | Alternative statistical and theoretical analysis of fluorophilicity显示文摘 | Pablo R Duchowicz Francisco M Fern ndez Eduardo A Castro | 2004 | Journal of Fluorine Chemistry2004，125，： | 1 |
| 19 | Intraoperative ERCP for the Management of Choledocholithiasis: A Comparative Study显示文摘 | Luis R. Rabago Maria Delgado Cristina de Vicente Ignacio Moral Nuria Ventosa Jose Luis Castro Jaime Vazquez Echarri Rosa Llorente Jose Romeo Francisco Gea Jose Luis Martinez Veiga | 2004 | Gastrointestinal Endoscopy2004，，5： | 1 |
| 20 | Creatine supplementation prevents fatty liver in rats fed choline-deficient diet: a burden of one-carbon and fatty acid metabolism显示文摘 | Rafael Deminice Gabriela Salim Ferreira de Castro Lucas Vieira Francisco Lilian Eslaine Costa Mendes da Silva Jo?o Felipe Rito Cardoso Fernando Tadeu Trevisan Frajacomo Bruno Gonzaga Teodoro Leonardo dos Reis Silveira Alceu Afonso Jordao | 2015 | The Journal of Nutritional Biochemistry2015，，4： | 1 |
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