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| 1 | Phase Ⅰ of cardiac rehabilitation:A new challenge for evidence based physiotherapy显示文摘Cardiac rehabilitation protocols applied during the inhospital phase(phaseⅠ)are subjective and their results are contested when evaluated considering what should be the three basic principles of exercise prescription:specificity,overload and reversibility.In this review,we focus on the problems associated with the models of exercise prescription applied at this early stage in-hospital and adopted today,especially the lack of clinical studies demonstrating its effectiveness.Moreover,we present the concept of'periodization'as a useful tool in the search for better results. | Rafael Michel de Macedo JoséRocha Faria-Neto Costantino Ortiz Costantini Dayane Casali Andrea Pires Muller Costantino Roberto Costantini Katherine Athayde Teixeira de Carvalho Luiz César Guarita-Souza | 2011 | World Journal of Cardiology2011，3，7： | 11 |
| 2 | Fatty liver disease in severe obese patients:Diagnostic value of abdominal ultrasound显示文摘AIM:To evaluate the sensitivity and specificity of abdominal ultrasound (US) for the diagnosis of hepatic steatosis in severe obese subjects and its relation to histological grade of steatosis. METHODS: A consecutive series of obese patients, who underwent bariatric surgery from October 2004 to May 2005, was selected. Ultrasonography was performed in all patients as part of routine preoperative time and an intraoperative wedge biopsy was obtained at the beginning of the bariatric surgery. The US and histological findings of steatosis were compared, considering histology as the gold standard. RESULTS: The study included 105 patients. The mean age was 37.2 ± 10.6 years and 75.2% were female. The histological prevalence of steatosis was 89.5%. The sensitivity and specificity of US in the diagnosis of hepatic steatosis were, respectively, 64.9% (95% CI: 54.9-74.3) and 90.9% (95% CI: 57.1-99.5). The positive predictive value and negative predictive value were, respectively, 98.4% (95% CI: 90.2-99.9) and 23.3% (95% CI: 12.3-39.0). The presence of steatosis onUS was associated to advanced grades of steatosis on histology (P = 0.016). CONCLUSION: Preoperative abdominal US in our series has not shown to be an accurate method for the diagnosis of hepatic steatosis in severe obese patients. Until another non-invasive method demonstrates better sensitivity and specificity values, histological evaluation may be recommended to these patients undergoing bariatric surgery. | Alessandro de Moura Almeida Helma Pinchemel Cotrim Daniel Batista Valente Barbosa Luciana Gordilho Matteoni de Athayde Adimeia Souza Santos Almir Galvo Vieira Bitencourt Luiz Antonio Rodrigues de Freitas Adriano Rios Erivaldo Alves | 2008 | World Journal of Gastroenterology2008，14，9： | 10 |
| 3 | Phenolic composition and inhibitory activity of Mangifera indica and Mucuna urens seeds extracts against key enzymes linked to the pathology and complications of type 2 diabetes显示文摘Objective:To investigate the phenolic compounds composition and the inhibitory activity of Mangifera indica(M.indica) and Mucuna urens(M.urens) seeds extracts against some key enzymes(-amylase,-glucosidasc and aldose reductase) implicated in the pathology and complications of type 2 diabetes in vitro.Methods:Reverse phase chromatographic quantification of the major flavonoids and phenolic acids in the seeds extracts was carried out using high performance liquid chromatography coupled with diode array detection.The inhibitory activities of the seeds extracts against-amylase and-glucosidase were estimated using soluble starch and p-nitrophenylglucopyranosidc as their respective substrates.Inhibition of aldose reductase activity by the extracts was assayed using partially purified lens homogenate of normal male rat as source of enzyme;inhibition of Fe^(2+)-induced lipid peroxidation by extracts was tested in rat pancreas homogenate.Results:The chromatography result revealed that extracts of both seeds had appreciable levels of some major flavonoids and phenolic acids of pharmacological importance,including gallic acid,chlorogenic acid,caffeic acid,ellagic acid,catechin,rutin,quercitrin.quercetin and kaempferol.Extracts of both seeds effectively inhibited-amylase,-glucosidase and aldose reductase activities in a dose-dependent manner,having inhibitory preference for these enzymes in the order of aldose reductase>-glucosidase>-amylase.With lower half-maximal inhibitory concentrations(IC50)against-amylase,-glucosidase,and aldose reductase,M.indica had stronger inhibitory potency against these enzymes than M.urens.Extracts of both seeds also inhibited Fe2+-induced lipid peroxidation in a dose-dependent pattern,with M.indica being more potent than M.urens.Conclusions:The results obtained provide support for a possible use of M.indica and M.urens seeds in managing hyperglycemia and preventing the complications associated with it in type 2diabetes. | Emmanuel Anyachukwu Irondi Ganiyu Oboh Afolabi Akintunde Akindahunsi Aline Augusti Boligon Margareth Linde Athayde | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，11： | 4 |
| 4 | Benefit of stem cells and skeletal myoblast cells in dilated cardiomyopathies显示文摘Although some authors suggest that there is mitotic division in the heart,most cardiomyocytes do not have the capacity to regenerate after myocardial infarction and when this occurs there is a deterioration of contractile function,and if the area of infarction is extensive ventricular remodeling may occur,leading to the development of heart failure.Cell transplantation into the myocardium with the goal of recovery of cardiac function has been extensively studied in recent years. The effects of cell therapy are based directly on the cell type used and the type of cardiac pathology.For myocardial ischemia in the hibernating myocardium, bone marrow cells have functional benefits,however these results in transmural fibrosis are not evident. In these cases there is a benefit of implantation with skeletal myoblasts,for treating the underlying cause of disease,the loss of cell contractility. | Luiz César Guarita-Souza Júlio César Francisco Rossana Simeoni Jose Rocha Faria-Neto Katherine Athayde Teixeira de Carvalho | 2011 | World Journal of Cardiology2011，3，3： | 4 |
| 5 | Phenolics extract of Tetrapleura tetraptera fruit inhibits xanthine oxidase and Fe^2+-induced lipid peroxidation in the kidney,liver,and lungs tissues of rats in vitro显示文摘The phenolics composition and inhibitory activity of Tetrapleura tetraptera fruit extract on xanthine oxidase(XO)and Fe2+-induced lipid peroxidation in the kidney,liver and lungs tissues of rats were evaluated in vitro.Phenolics(flavonoids and phenolic acids)were quantified using reverse-phase high performance liquid chromatrography coupled with diode array detection(HPLC-DAD).The XO and Fe2+-induced lipid peroxidation inhibitory abilities of the extract were evaluated using spectrophotometric methods.The extract contained some flavonoids and phenolic acids,including catechin,epicatechin,rutin,quercetin,luteolin,apigenin;gallic,chlorogenic,caffeic and ellagic acids that are beneficial to health.The extract inhibited XO in the kidney,liver and lungs tissues in a dose-dependent manner.The half-maximal inhibitory concentrations(IC50)of the extract on XO from the tissues varied significantly(P<0.05),and were in the order of liver>kidney>lungs.The extract also inhibited Fe2+-induced lipid peroxidation in a dose-dependent pattern,having IC50 in the order of liver>lungs>kidney.T.tetraptera fruit extract could be a promising nutraceutical for preventing and managing hyperuricaemia and the associated disease conditions,due to its ability to inhibit XO;this bioactivity is attributable to combined effect of its flavonoids and phenolic acids. | Emmanuel Anyachukwu Irondi Ganiyu Oboh Samson Olalekan Agboola Aline Augusti Boligon Margareth Linde Athayde | 2016 | Food Science and Human Wellness2016，5，1： | 3 |
| 6 | Randomized clinical study for assessment of incision characteristics and pain associated with LESS versus laparoscopic cholecystectomy显示文摘 | Fernando Athayde Veloso Madureira José Eduardo Ferreira Manso Delta Madureira Fo Antonio Carlos Garrido Iglesias | 2013 | Surgical Endoscopy2013，，3： | 2 |
| 7 | Maternal plasma from pregnant women with umbilical placental vascular disease does not affect endothelial cell mRNA expression of nitric oxide synthase显示文摘 | Wang X Athayde N Trudinger B | 2004 | J Soc Gynecol Investig2004，11，3： | 1 |
| 8 | Atypical embryo phenotypes identified by time-lapse microscopy:high preva- lence and association with embryo 显示文摘 | Athayde WK Chen AA Conaghan J | 2014 | Fertil Steril2014，101，6： | 1 |
| 9 | A role for the novel cytokine RANTES in pregnancy and parturition显示文摘 | Athayde N Romero R Maymon E | 1999 | Obstet Gynecol1999，181，4： | 1 |
| 10 | Clinical relevance of oxidative stress and sperm ehrematin damage in male infertility : an evidence based analysis显示文摘 | Cecuzza M Sikka SC Athayde KS | 2007 | Int Braz J Urel2007，33，5： | 1 |
| 11 | Grade 3varicocele in fertile men:a different entity显示文摘 | Cocuzza M Athayde KS Alvarenga C | 2012 | J Urol2012，187，： | 1 |
| 12 | Effect of the treatment with achyrocline satureioides (free and nanocapsules essential oil) and diminazene aceturate on hematological and biochemical parameters in rats infected by trypanosoma evansi显示文摘 | Guilherme M. Do Carmo Matheus D. Baldissera Rodrigo A. Vaucher Virginia Cielo Rech Camila B. Oliveira Michele Rorato Sagrillo Aline A. Boligon Margareth L. Athayde Marta P. Alves Raqueli T. Fran?a Sonia T.A. Lopes Claiton I. Schwertz Ricardo E. Mendes Sil | 2014 | Experimental Parasitology2014，，： | 1 |
| 13 | C-erbB2 over-expression in endometrial hyperplasia induced by estrogens显示文摘 | Maia H Jr Maltez A Athayde C | 2002 | Maturitas2002，43，1： | 1 |
| 14 | Antioxidant activities of flavonol derivatives from the leaves and stem bark of Scutia buxifolia Reiss显示文摘 | Aline Augusti Boligon Romaiana Picada Pereira Andriéli Cassel Feltrin Michel Mansur Machado Vanessa Janovik Jo?o Batista Teixeira Rocha Margareth Linde Athayde | 2009 | Bioresource Technology2009，，24： | 1 |
| 15 | Serum 25-hydroxyvitamin D and glycated haemoglobin levels in women with gestational diabetes mellitus显示文摘 | Lan S Gunton J Athayde N | 2011 | Med J Aust2011，194，7： | 1 |
| 16 | Functional outcomes in patients with ehronie obstructive pulmonary disease: a multiva- riate analysis 显示文摘 | Athayde FT Vieira DS Britto RR | 2014 | Braz J Phys Ther2014，18，1： | 1 |
| 17 | Atypical embryo phenotypes identified by time-lapse microscopy: high prevalence and association with embryo 显示文摘 | Athayde WK Chen AA Conaghan J | 2014 | Fertil Steril2014，101，6： | 1 |
| 18 | Acute kindy inju- ry due to rhabdomyolysis显示文摘 | Athayde lima RS Silva Junior GB Liborio AB | 2008 | Saudi J Kidney Dis Transplant2008，19，5： | 1 |
| 19 | A role for matrix metallo- proteinase-9 in spontaneous rupture of the fetal membranes 显示文摘 | Athayde N Edwin SS Romero R | 1998 | Am J Obstet Gynecol1998，179，5： | 1 |
| 20 | Development of normal reference values for seminal reactive oxygen species and their correlation with leukocytes and semen parameters in a fertile population显示文摘 | ATHAYDE KS COCUZZA M AGAIWAL A | | 0，，04： | 1 |
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