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| 1 | The Deep-Time Digital Earth program:data-driven discovery in geosciences显示文摘Current barriers hindering data-driven discoveries in deep-time Earth(DE)include:substantial volumes of DE data are not digitized;many DE databases do not adhere to FAIR(findable,accessible,interoperable and reusable)principles;we lack a systematic knowledge graph for DE;existing DE databases are geographically heterogeneous;a significant fraction of DE data is not in open-access formats;tailored tools are needed.These challenges motivate the Deep-Time Digital Earth(DDE)program initiated by the International Union of Geological Sciences and developed in cooperation with national geological surveys,professional associations,academic institutions and scientists around the world.DDE’s mission is to build on previous research to develop a systematic DE knowledge graph,a FAIR data infrastructure that links existing databases and makes dark data visible,and tailored tools for DE data,which are universally accessible.DDE aims to harmonize DE data,share global geoscience knowledge and facilitate data-driven discovery in the understanding of Earth’s evolution. | Chengshan Wang Robert MHazen Qiuming Cheng Michael HStephenson Chenghu Zhou Peter Fox Shu-zhong Shen Roland Oberhansli Zengqian Hou Xiaogang Ma Zhiqiang Feng Junxuan Fan Chao Ma Xiumian Hu Bin Luo Juanle Wang Craig M.Schiffries | 2021 | National Science Review2021，8，9： | 14 |
| 2 | Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria显示文摘 | Bruno Dubois Howard H Feldman Claudia Jacova Harald Hampel José Luis Molinuevo Kaj Blennow Steven T DeKosky Serge Gauthier Dennis Selkoe Randall Bateman Stefano Cappa Sebastian Crutch Sebastiaan Engelborghs Giovanni B Frisoni Nick C Fox Douglas Galasko Ma | 2014 | Lancet Neurology2014，，6： | 7 |
| 3 | Ontology Dynamics in a Data Life Cycle: Challenges and Recommendations from a Geoscience Perspective显示文摘Ontologies are increasingly deployed as a computer-accessible representation of key semantics in various parts of a data life cycle and, thus, ontology dynamics may pose challenges to data management and re-use. By using examples in the field of geosciences, we analyze challenges raised by ontology dynamics, such as heavy reworking of data, semantic heterogeneity among data providers and users, and error propagation in cross-discipline data discovery and re-use. We also make recommendations to address these challenges:(1) communities of practice on ontologies to reduce inconsistency and duplicated efforts;(2) use ontologies in the procedure of data collection and make them accessible to data users; and(3) seek methods to speed up the reworking of data in a Semantic Web context. | Xiaogang Ma Peter Fox Eric Rozell Patrick West Stephan Zednik | 2014 | Journal of Earth Science2014，25，2： | 3 |
| 4 | Data-Driven Discovery in Mineralogy: Recent Advances in Data Resources, Analysis, and Visualization显示文摘Large and growing data resources on the diversity, distribution, and properties of minerals are ushering in a new era of data-driven discovery in mineralogy. The most comprehensive international mineral database is the IMA database, which includes information on more than 5400 approved mineral species and their properties, and the mindat.org data source, which contains more than 1 million species/locality data on minerals found at more than 300 000 localities. Analysis and visualization of these data with diverse techniques—including chord diagrams, cluster diagrams, Klee diagrams, skyline diagrams, and varied methods of network analysis—are leading to a greater understanding of the co-evolving geosphere and biosphere. New data-driven approaches include mineral evolution, mineral ecology, and mineral network analysis—methods that collectively consider the distribution and diversity of minerals through space and time. These strategies are fostering a deeper understanding of mineral co-occurrences and, for the first time, facilitating predictions of mineral species that occur on Earth but have yet to be discovered and described. | Robert M. Hazen Robert T. Downs Ahmed Eleish Peter Fox Olivier C. Gagné Joshua J. Golden Edward S. Grew Daniel R. Hummer Grethe Hystad Sergey V. Krivovichev Congrui Li Chao Liu Xiaogang Ma Shaunna M. Morrison Feifei Pan Alexander J. Pires Anirudh Prabhu Jolyon Ralph Simone E. Runyon Hao Zhong | 2019 | Engineering2019，5，3： | 2 |
| 5 | 弓形虫感染引起小胶质细胞与神经元的接触以及细胞体周边抑制性突触丧失显示文摘大脑内的感染和炎症会引起神经元连通性和功能的改变。细胞内的原生动物寄生虫,弓形虫,是一种感染脑部的病原体,可引起脑炎和癫痫发作。这种寄生虫的持续感染还与行为改变和发生精神疾病(包括精神分裂症)的风险增加有关。目前来自人类和小鼠模型的研究证据表明,癫痫发作和精神分裂症均由抑制性突触的丧失或功能障碍引起。与此相符,我们最近报道了持续性弓形虫感染改变谷氨酸脱羧酶67(GAD67)的分布,该酶在抑制性突触中催化GABA的合成。这些变化可能反映突触前装置在抑制性神经元中的重新分布或抑制性神经末梢的丧失。为了直接评估后者的可能性,我们采用序列块面扫描电子显微镜(SBFSEM)并量化寄生虫感染后新皮质和海马中的细胞体周边抑制性突触。持续感染不仅导致明显的细胞体周边突触丧失,而且还诱导髓样来源的细胞对神经元细胞体的包封。免疫组织化学、遗传和超微结构分析显示,这些髓样来源的细胞包括活化的小胶质细胞。最后,超微结构分析确定了包膜于细胞体周围神经末梢的髓样来源的细胞,提示它们可能会主动置换或吞噬突触元件。因此,这些结果表明,活化的小胶质细胞有助于寄生虫感染后细胞体周围抑制突触损失,并对于弓形虫的持续感染可能如何导致癫痫发作和精神疾病提供了一种新的机制。 | Carrillo GL Ballard VA Glausen T Boone Z Teamer J Hinkson CL Wohlfert EA Blader IJ Fox MA 杜一星(编译) | 2020 | 神经损伤与功能重建2020，15，3： | 2 |
| 6 | Guidelines on the management of stable angina pectoris:executive summary:the Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology显示文摘 | Fox K Garcia MA Ardissino D | 2006 | Eur Heart J2006，27，： | 1 |
| 7 | Hydrogen photoproduction by Nation/cadmium sulfide/platinum films in water/sulfide ion solutions 显示文摘 | Mau AWH Huang CB Kakuta N Bard AJ Campion A Fox MA | 1984 | J Am Chem Soc1984，106，22： | 1 |
| 8 | Marine ecoregions of the world:a bioregionalization of coastal and shelf areas显示文摘 | Spalding MD Fox HE Allen GR Davidson N Ferdafia ZA Finlayson M Halpern BS Jorge MA Lombana AL Lourie SA Martin KD Manus EC Molnar J Recchia CA Robertson J | | 0，，： | 1 |
| 9 | Heterogeneous photocatalysis 显示文摘 | Fox MA Dulay MT | 1993 | Chem Rev1993，93，1： | 1 |
| 10 | Novel roles for collagens in wiring the vertebrate nervous system 显示文摘 | Fox MA | 2008 | Curr Opin Cell Biol2008，20，5： | 1 |
| 11 | Novel actions of estrogen to promote proliferation: integration of cytoplasmic and nuclear pathways 显示文摘 | Fox EM Andrade J Shupnik MA | 2009 | Steroids2009，74，7： | 1 |
| 12 | Enhanced detection of focal brain responses using intersubject averaging and change-distribution analysis of subtracted PET images显示文摘 | Fox PT Mintun MA Reiman EM | 1988 | Journal of Cerebral Blood Flow and Metabolism1988，8，5： | 1 |
| 13 | Guidelines on the management of stable angina pectofis : executive summary : the task force on the management of stable angina pectoris european society of cardiology显示文摘 | Fox K Garcia MA Ardissino D | 2006 | Eur Heart J2006，27，11： | 1 |
| 14 | Common femoral artery ligation and local debridement:a safe treatment for infected femoral artery pseudoaneurysms显示文摘 | ARORA S WEBER MA FOX CJ | 2001 | J Vasc Surg2001，33，5： | 1 |
| 15 | Phosphodiesterase-Ialpha/autotaxin: a counteradhesive proteinexpressed by oligodendrocytes during onset of myelination 显示文摘 | FOX MA COLELLO RJ MACKLIN WB | 2003 | Mol Cell Neurosci2003，23，3： | 1 |
| 16 | ERI3 in breast cancer- onlooker, passive player, or active protector?显示文摘 | Fox EM Davis RJ Shupnik MA | 2008 | Steroids2008，73，11： | 1 |
| 17 | Guidelines on the management of stable angina peetoris: executive summary: The task Force on the Management of Stable Angina Peetoris of The European Society ofCardiology显示文摘 | Fox K Garcia MA Ardissino D | 2006 | EurHeart J2006，27，11： | 1 |
| 18 | Gender Differences in memory and learning in children with Insulin-Dependent Diabetes Menitus(IDDM) over a 4-year follow-up interval显示文摘 | Fox MA Chen RS Holmes CS | 2003 | Journal of Pediatric Psychology2003，28，8： | 1 |
| 19 | Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Sta- ble Angina Pectoris of the European Society of Cardiol- ogy显示文摘 | Fox K Garcia MA Ardissino D | 2006 | Eur Heart J2006，27，11： | 1 |
| 20 | A synaptic nidogen :de- velopmental regulation and role of nidogen-2 at the neu- romuscular junction 显示文摘 | Fox MA Ho MS Smyth N | 2008 | Neural Dev2008，3，25： | 1 |
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