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| 1 | Nature:研究鉴定出蛋白Nlrp9b抵抗轮状病毒感染机制显示文摘轮状病毒(rotavirus)是婴儿和儿童罹患肠胃炎和腹泻的一种最为常见的原因,每年导致全世界大约21.5万人死亡。它是高度传染性的和潜在致命性的。这种病毒特异性地感染宿主小肠中的肠上皮细胞,并且已进化出抵抗干扰素和NF-KB信号的策略来躲避免疫系统,这就提出一个问题:其他的宿主因子是否参与肠道粘膜中的抗病毒反应。不过,针对体内(特别是通过NLR炎性体)检测和限制肠道病毒的机制,人们知之甚少。 | Shu Zhu, Zheng Wei, Noah W. Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Liang Shan, Richard A. Flavell Siyuan Ding, Ningguo Feng, Harry B. Greenberg Siyuan Ding, Harry B. Greenberg Penghua Wang, Yujiao Zhao Wen Pan, Jun Lu Jun Zhao, Yuval Kluger Kellie A. Jurado, Clara Abraham, Erol Fikrig Erol Fikrig, Richard A. Flavell | 2017 | 现代生物医学进展2017,17,27: | 10 |
| 2 | DUCTILEBRITTLETRANSITION OF POLYCRYSTALLINE Ni_3Al WITH VARYING GRAIN SIZE显示文摘It is known that in B (un)doped Ni 3Al polycrystals, the dependence of yield strength on grain size follows the Hall Petch relationship: σ y= σ 0+ K y d -1/2 , and the slope K y can be reduced by B doping owing to the lowering of grain boundary resistance to slip transmission. If the intergranular cracking in polycrystalline Ni 3Al occurs from the microcavity along the grain boundaries, the effective external tensile stress for the propagation of the crack like microcavity along the grain boundaries can be deduced as: σ f= σ i+ K u d -1/2 , where K u reflects the effects of such factors as environment, strain rate, boron doping and the orientation of the grain boundary on the trend of intergranular cracking. For loaded polycrystalline Ni 3Al, it should be competitive between the intergranular cracking and slip transmission across the grain boundary. Therefore, comparing the varieties of both σ y and σ f with grain size, the dependence of ductile brittle transition on grain size, and the effects of the above factors on ductile brittle transition can be expected. The model also predicts that there exists a critical grain size for the ductile brittle transition of polycrystalline Ni 3Al alloys, and B doping can increase the critical grain size due to the reduction of the slope K y and the increase of K u. The reported experimental results verified the above model. | G. W. Han, D. Feng and C. S. Lee Central Iron & Steel Research Institute, Beijing 100081, China Dept. Physical & Mater. Sci., City University of Hong Kong Hong Kong, China | 1999 | 中国有色金属学会会刊:英文版1999,9,S1: | 7 |
| 3 | One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering显示文摘 | Haoyi Wang Hui Yang Chikdu S. Shivalila Meelad M. Dawlaty Albert W. Cheng Feng Zhang Rudolf Jaenisch | 2013 | Cell2013,,4: | 5 |
| 4 | Effects of PI3-k/Akt short hairpin RNA on proliferation, fibronectin production and synthesis of thrombospondin-1 and transforming growth factor-beta(1 ) in glomerular mesangial cells induced by sublytic C5b-9 complexes显示文摘 | Gao, L. Zhang, Y. Qiu, W. Xu, W. Feng, X. Ren, J. Jiang, X. Wang, H. Zhao, D. Wang, Y. | 2009 | 南京医科大学学报(自然科学版)2009,29,3: | 5 |
| 5 | Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury显示文摘 | Neel R. Sodha Richard T. Clements Jun Feng Yuhong Liu Cesario Bianchi Eszter M. Horvath Csaba Szabo Gregory L. Stahl Frank W. Sellke | 2009 | The Journal of Thoracic and Cardiovascular Surgery2009,,: | 3 |
| 6 | Comparison of laparoscopically assisted and open radical distal gastrectomy with extended lymphadenectomy for gastric cancer management显示文摘 | W. Ziqiang Q. Feng C. Zhimin W. Miao Q. Lian L. Huaxing Y. Peiwu | 2006 | Surgical Endoscopy2006,,11: | 2 |
| 7 | Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis显示文摘 | Habtom W. Ressom Jun Feng Xiao Leepika Tuli Rency S. Varghese Bin Zhou Tsung-Heng Tsai Mohammad R. Nezami Ranjbar Yi Zhao Jinlian Wang Cristina Di Poto Amrita K. Cheema Mahlet G. Tadesse Radoslav Goldman Kirti Shetty | 2012 | Analytica Chimica Acta2012,,: | 2 |
| 8 | 小儿体外循环中的脑保护显示文摘手术技术和术后监护的进步已经大大降低了小儿先天性心脏病(先心病)手术的死亡率,并改善了患儿的长期预后。最近的研究显示[1],尽管病例的复杂性有所提高,但术后的院内死亡率低于3%,而且一项大样本社会心理学研究显示,在儿童时期接受过先心病纠治手术的成年人能够较好的适应社会。 | Xiaowei W. Su Feng Qiu Akif tindar | 2011 | 中国体外循环杂志2011,9,1: | 2 |
| 9 | Comparison of laparoscopically assisted and open radical distal gastrectomy with extended lymphadenectomy for gastric cancer management显示文摘 | W. Ziqiang Q. Feng C. Zhimin W. Miao Q. Lian L. Huaxing Y. Peiwu | 2006 | Surgical Endoscopy2006,,11: | 2 |
| 10 | Using Prior Shapes in Geometric Active Contours in a Variational Framework显示文摘 | Yunmei Chen Hemant D. Tagare Sheshadri Thiruvenkadam Feng Huang David Wilson Kaundinya S. Gopinath Richard W. Briggs Edward A. Geiser | 2002 | International Journal of Computer Vision2002,,3: | 2 |
| 11 | 查看详情显示文摘 | Han W. W Wang Y Zhou Y. H Yao Y. Li Z.S. Feng Y | | 0,,: | 1 |
| 12 | Programmed death‐1/B7‐H1 negative costimulation protects mouse liver against ischemia and reperfusion injury显示文摘 | Haofeng Ji Xiuda Shen Feng Gao Bibo Ke Maria Cecilia S. Freitas Yoichiro Uchida Ronald W. Busuttil Yuan Zhai Jerzy W. Kupiec‐Weglinski | 2010 | Hepatology2010,,4: | 1 |
| 13 | Genome-wide Association and Follow-Up Replication Studies Identified ADAMTS18 and TGFBR3 as Bone Mass Candidate Genes in Different Ethnic Groups显示文摘 | Dong-Hai Xiong Xiao-Gang Liu Yan-Fang Guo Li-Jun Tan Liang Wang Bao-Yong Sha Zi-Hui Tang Feng Pan Tie-Lin Yang Xiang-Ding Chen Shu-Feng Lei Laura M. Yerges Xue-Zen Zhu Victor W. Wheeler Alan L. Patrick ClareAnn H. Bunker Yan Guo Han Yan Yu-Fang Pei Yin-Pi | 2009 | The American Journal of Human Genetics2009,,3: | 1 |
| 14 | Polar organic tracers in PM2.5 aerosols from forests in eastern China显示文摘 | Wang W. Wu M. H. Li L. Zhang T. Liu X. D. Feng J. L. Li H. J. Wang Y. J. Sheng G. Y. Claeys M. Fu J. M | 2008 | 2008 (150)2008,,150: | 1 |
| 15 | Isolation and identification of a novel flavonoid from Penthorum chinense P.显示文摘 | H. -W. Wang Y. -Q. Liu C. -G. Feng | 2006 | Journal of Asian Natural Products Research2006,,8: | 1 |
| 16 | The receptor—mediated accumulation of triglyceride in macrophage exposed to very low density lipoproteins显示文摘 | Feng Zongchen Sandra R. Bates Godfrey S. Getz Robert W. Wissler | 1983 | Acta Academiae Medicinae Wuhan1983,,1: | 1 |
| 17 | Clinical features of myasthenia gravis in southern China: a retrospective review of 2,154 cases over 22 years显示文摘 | X. Huang W. B. Liu L. N. Men H. Y. Feng Y. Li C. M. Luo L. Qiu | 2013 | Neurological Sciences2013,,6: | 1 |
| 18 | Minimum Spanning Table and Optimal Expansion of Competence Set显示文摘 | J. W. Feng P. L. Yu | 1998 | Journal of Optimization Theory and Applications1998,,3: | 1 |
| 19 | A cobalt-doped transparent glass ceramic saturable absorber Q-switch for a LD pumped Yb 3+ /Er 3+ glass microchip laser显示文摘 | S. Y. Feng C. L. Yu L. Chen S. G. Li W. Chen L. L. Hu | 2010 | Laser Physics2010,,8: | 1 |
| 20 | Underground water Cherenkov muon detector array with the Tibet air shower array for gamma-ray astronomy in the 100 TeV region显示文摘 | M. Amenomori S. Ayabe X. J. Bi D. Chen S. W. Cui Danzengluobu L. K. Ding X. H. Ding C. F. Feng Zhaoyang Feng Z. Y. Feng X. Y. Gao Q. X. Geng H. W. Guo H. H. He M. He K. Hibino N. Hotta Haibing Hu H. B. Hu J. Huang Q. Huang H. Y. Jia F. Kajino K. Kasahara | 2007 | Astrophysics and Space Science (-)2007,,1: | 1 |