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| 1 | Vitamin D receptor gene polymorphisms and hepatocellular carcinoma in alcoholic cirrhosis显示文摘AIM: To assess the relationship between vitamin D re-ceptor (VDR) gene polymorphisms and the presence of hepatocellular carcinoma (HCC). METHODS: Two-hundred forty patients who underwent liver transplantation were studied. The etiologies of liver disease were hepatitis C (100 patients), hepatitis B (37) and alcoholic liver disease (103). A group of 236 healthy subjects served as controls. HCC in the explanted liver was detected in 80 patients. The following single nucle-otide gene polymorphisms of the VDR were investigatedby polymerase chain reaction and restriction fragment length polymorphism: FokI C>T (F/f), BsmI A>G (B/b), ApaI T>G (A/a) and TaqI T>C (T/t) (BAT). RESULTS: The frequencies of genotypes in patients without and with HCC were for FokI F/F = 69, F/f = 73, f/f = 18 and F/F = 36, F/f = 36, f/f = 8; BsmI b/b = 45, B/b = 87, B/B = 28 and b/b = 33, B/b = 35, B/B = 12; for ApaI A/A = 53, A/a = 85, a/a = 22 and A/A = 27, A/a = 38, a/a = 15; for TaqI T/T = 44, T/t = 88, t/t = 28 and T/T = 32, T/t = 38, t/t = 10. Carriage of the b/b genotype of BsmI and the T/T genotype of TaqI was signif icantly associated with HCC (45/160 vs 33/80, P < 0.05 and 44/160 vs 32/80, P < 0.05, respectively). The absence of the A-T-C protective allele of BAT was signif i-cantly associated with the presence of HCC (46/80 vs 68/160, P < 0.05). A strong association was observed between carriage of the BAT A-T-C and G-T-T haplotypes and HCC only in alcoholic liver disease (7/46 vs 12/36 vs 11/21, P < 0.002, respectively).CONCLUSION: VDR genetic polymorphisms are sig-nificantly associated with the occurrence of HCC in patients with liver cirrhosis. This relationship is more specific for patients with an alcoholic etiology. | Edmondo Falleti Davide Bitetto Carlo Fabris Annarosa Cussigh Elisabetta Fontanini Ezio Fornasiere Elisa Fumolo Sara Bignulin Sara Cmet Rosalba Minisini Mario Pirisi Pierluigi Toniutto | 2010 | World Journal of Gastroenterology2010，16，24： | 14 |
| 2 | CHIM-geoelectrochemical method in search of concealed mineralisation in China and Australia显示文摘A version of the geoelectrochemical prospecting technique developed in China was demonstrated in China and Australia to test its suitability under both Chinese and Australian conditions.This paper briefly describes the mechanism and effectiveness of the technique applied to search of concealed mineralisation through regolith cover,based on both experimental and field tests.This paer deals with three main aspects of the method: a) how metallic ions are released from orebodies by electrochemical dissolution;b)how these ions migrate to the collector and are deposited as elements by electrochemical extraction in the presence of an electric field; and c) the effectiveness of the method illustrated by some case studies. | LUO Xianrong HOU Baohong WEN Meilanna ZENG Nanshi John Keeling Roger Fidler Adrian Fabris | 2008 | Chinese Journal Of Geochemistry2008，27，2： | 8 |
| 3 | Influence of coagulation mechanisms and floc formation on filterability显示文摘Minimizing particles in water is a key goal for improving drinking water quality and safety.The media filtration process,as the last step of the solid–liquid separation process,is largely influenced by the characteristics of flocs,which are formed and controlled within the coagulation process.In a laboratory-based study,the impacts of the physical characteristics of flocs formed using aluminum sulfate on the filtration treatment of two comparative water samples were investigated using a photometric dispersion analyzer and a filterability apparatus.In general,the optimum dosage for maximizing filterability was higher than that for minimizing turbidity under neutral p H conditions.For a monomeric aluminum-based coagulant,the charge neutralization mechanism produced better floc characteristics,including floc growth speed and size,than the sweep flocculation mechanism.In addition,the charge neutralization mechanism showed better performance compared to sweep flocculation in terms of DOC removal and floc filterability improvement for both waters,and showed superiority in turbidity removal only when the raw water had high turbidity.For the different mechanisms,the ways that floc characteristics impacted on floc filterability also differed.The low variation in floc size distribution obtained under the charge neutralization mechanism resulted in the flocs being amenable to removal by filtration processes.For the sweep flocculation mechanism,increasing the floc size improved the settling ability of flocs,resulting in higher filter efficiency. | Ruyuan Jiao Rolando Fabris Christopher W.K.Chow Mary Drikas John van Leeuwen Dongsheng Wang Zhizhen Xu | 2017 | Journal of Environmental Sciences2017，29，7： | 6 |
| 4 | Functional topography of the corpus callosum investigated by DTI and f MRI显示文摘This short review examines the most recent functional studies of the topographic organization of the human corpus callosum, the main interhemispheric commissure. After a brief description of its anatomy, development, microstructure, and function, it examines and discusses the latest findings obtained using diffusion tensor imaging(DTI) and tractography(DTT) and functional magnetic resonance imaging(f MRI), three recently developed imaging techniques that have significantly expanded and refined our knowledge of the commissure. While DTI and DTT have been providing insights into its microstructure, integrity and level of myelination, f MRI has been the key technique in documenting the activation of white matter fibers, particularly in the corpus callosum. By combining DTT and f MRI it has been possible to describe the trajectory of the callosal fibers interconnecting the primary olfactory, gustatory, motor, somatic sensory, auditory and visual cortices at sites where the activation elicited by peripheral stimulation was detected by fMRI. These studies have demonstrated the presence of callosal fiber tracts that cross the commissure at the level of the genu, body, and splenium, at sites showing f MRI activation. Altogether such findings lend further support to the notion that the corpus callosum displays a functional topographic organization that can be explored with f MRI. | Mara Fabri Chiara Pierpaoli Paolo Barbaresi Gabriele Polonara | 2014 | World Journal of Radiology2014，6，12： | 6 |
| 5 | Prediction of DOM removal of low specific UV absorbance surface waters using HPSEC combined with peak fitting显示文摘High performance size exclusion chromatography (HPSEC) is used in water quality research primarily to determine the molecular weight distribution of the dissolved organic matter (DOM), but by applying peak fitting to the chromatogram, this technique can also be used as a tool to model and predict DOM removal. Six low specific UV absorbance (SUVA) source waters were treated using coagulation with alum and both the source and treated water samples were analysed using HPSEC. By comparing the molecular weight profiles of the source and treated waters, it was established that several DOM components were not effectively removed by alum coagulation even after high dosage alum treatment. A peak-fitting technique was applied based on the concept of linking the character (molecular weight profile) of the recalcitrant organics in the treated water with those of the source water. This was then applied to predict DOM treatability by determining the areas of the peaks which were assigned to removable organics from the source water molecular weight profile after peak fitting, and this technique quantified the removable and non-removable organics. The prediction was compared with the actual dissolved organic carbon (DOC) removal determined from jar testing and showed good agreement, with variance between 2% and 10%. This confirmed that this prediction approach, which was originally developed for high SUVA waters, can also be applied successfully to predict DOC removal in low SUVA waters. | Linan Xing Rolando Fabris W.K.Chow John van Leeuwen Mary Drikas Dongsheng Wang | 2012 | Journal of Environmental Sciences2012，24，7： | 4 |
| 6 | 勘查植物地球化学在我国不同地球化学景观区的应用现状及展望显示文摘勘查植物地球化学是通过分析植物器官来获取成矿元素信息的地球化学方法。我国学者在干旱荒漠区、森林沼泽区、半干旱和湿润半湿润中低山景观区开展了系统的勘查植物地球化学试验,厘定了一批适用于勘查植物地球化学调查的植物,为该方法的推广及应用奠定了良好基础。今后应进一步加强对勘查植物地球化学异常产生的机理、勘查植物地球化学数据库及指南建立、勘查植物地球化学异常遥感应用等方面的研究,更好地利用勘查植物地球化学方法服务矿产勘查工作。 | 王天刚 Adrian Fabris 姚仲友 Hou Baohong 赵宇浩 赵晓丹 朱意萍 | 2020 | 华东地质2020，41，1： | 4 |
| 7 | Tumor reactive stroma in cholangiocarcinoma:The fuel behind cancer aggressiveness显示文摘Cholangiocarcinoma(CCA) is a highly aggressive epithelial malignancy still carrying a dismal prognosis, owing to early lymph node metastatic dissemination and striking resistance to conventional chemotherapy. Although mechanisms underpinning CCA progression are still a conundrum, it is now increasingly recognized that the desmoplastic microenvironment developing in conjunction with biliary carcinogenesis, recently renamed tumor reactive stroma(TRS), behaves as a paramount tumor-promoting driver. Indeed, once being recruited, activated and dangerously co-opted by neoplastic cells, the cellular components of the TRS(myofibroblasts, macrophages, endothelial cells and mesenchymal stem cells) continuously rekindle malignancy by secreting a huge variety of soluble factors(cyto/chemokines, growth factors, morphogens and proteinases). Furthermore, these factors are long-term stored within an abnormally remodeled extracellular matrix(ECM), which in turn can deleteriously mold cancer cell behavior. In this review, we will highlight evidence for the active role played by reactive stromal cells(as well as by the TRS-associated ECM) in CCA progression, including an overview of the most relevant TRS-derived signals possibly fueling CCA cell aggressiveness. Hopefully, a deeper knowledge of the paracrine communications reciprocally exchanged between cancer and stromal cells will steer the development of innovative, combinatorial therapies, which can finally hinder the progression of CCA, as well as of other cancer types with abundant TRS, such as pancreatic and breast carcinomas. | Simone Brivio Massimiliano Cadamuro Mario Strazzabosco Luca Fabris | 2017 | World Journal of Hepatology2017，9，9： | 3 |
| 8 | TIPS for Budd-Chiari Syndrome: Long-Term Results and Prognostics Factors in 124 Patients显示文摘 | Juan Carlos Garcia–Pagán Mathis Heydtmann Sebastian Raffa Aurélie Plessier Sarwa Murad Federica Fabris Giovanni Vizzini Juan Gonzales Abraldes Simon Olliff Antonio Nicolini Angelo Luca Massimo Primignani Harry L.A. Janssen Dominique Valla Elwyn Elias Jaum | 2008 | Gastroenterology2008，，3： | 3 |
| 9 | Heart Valve Injury Induced by Mediastinum Radiotherapy in Cancer Treatment显示文摘 | Patricia Fraga Paiva Alice Assumpcao Soares Guilherme Sotto Maior do Valle Pinheiro Carolina Fraga Paiva Gisele Maria Campos Fabri Emanoel Guimaraes Paiva Carlos M. Campos Jose Fabfi Junior | 2018 | Journal of Pharmacy and Pharmacology2018，6，6： | 2 |
| 10 | Portal vein thrombosis in hepatocellular carcinoma: age and sex distribution in an autopsy study显示文摘 | Mario Pirisi Claudio Avellini Carlo Fabris Cathryn Scott Paola Bardus Giorgio Soardo Carlo A. Beltrami Ettore Bartoli | 1998 | Journal of Cancer Research and Clinical Oncology1998，，： | 2 |
| 11 | Recipient Interleukin-28B Rs12979860 C/T Polymorphism and Acute Cellular Rejection After Liver Transplantation: Role of the Calcineurin Inhibitor Used显示文摘 | Davide Bitetto Carlo Fabris Edmondo Falleti Ezio Fornasiere Claudio Avellini Sara Cmet Annarosa Cussigh Elisabetta Fontanini Mario Pirisi Stefano Ginanni Corradini Manuela Merli Antonio Molinaro Pierluigi Toniutto | 2012 | Transplantation Journal2012，，10： | 2 |
| 12 | Relationship Between Steatosis, Inflammation, and Fibrosis in Chronic Hepatitis C: A Meta-Analysis of Individual Patient Data显示文摘 | Gioacchino Leandro Alessandra Mangia Jason Hui Paolo Fabris Laura Rubbia–Brandt Guido Colloredo Luigi E. Adinolfi Tarik Asselah Julie R. Jonsson Antonina Smedile Norah Terrault Valerio Pazienza Maria Teresa Giordani Emiliano Giostra Aurelio Sonzogni Giuse | 2006 | Gastroenterology2006，，6： | 2 |
| 13 | The cardiac renin-angiotension system in heart failure显示文摘 | Johnston CI Fabris B Yoshida K | 1993 | Am Heart J1993，126，32： | 2 |
| 14 | Analysis of Liver Repair Mechanisms in Alagille Syndrome and Biliary Atresia Reveals a Role for Notch Signaling显示文摘 | Luca Fabris Massimiliano Cadamuro Maria Guido Carlo Spirli Romina Fiorotto Michele Colledan Giuliano Torre Daniele Alberti Aurelio Sonzogni Lajos Okolicsanyi Mario Strazzabosco | 2007 | The American Journal of Pathology2007，，： | 2 |
| 15 | Results of surgery for liver metastases (LM) after neoadjuvant chemotherapy (CT) with irinotecan + infusional fluorouracil/leucovorin ( Iri - FU/LV ) in patients (pts) with colorectal cancer ( CRC ) 显示文摘 | Clavero - Fabri MC Mitry E Chidiac J | 2003 | Proc Am Soc Clin Oncol2003，22，： | 1 |
| 16 | Antiviral treatment of hepatitis C显示文摘 | TONIUTYO P FABRIS C PIRISI M | 2006 | Expert Opin Pharmacother2006，7，15： | 1 |
| 17 | Minimalist Morphology:an Approach to Inflection显示文摘 | FABRI R | 1995 | Zeitschrif für Sprachwissenschaft1995，，14： | 1 |
| 18 | Dual adaptive control of nonlinear stochastic systems using neaural networks 显示文摘 | | 1998 | Automatica1998，34，2： | 1 |
| 19 | Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseases显示文摘 | Fabris L Cadamuro M Fiorotto R | 2006 | Hepatology2006，43，5： | 1 |
| 20 | Upregulation of translationalmachinery and distinct genetic subgroups characterise hyperdiploidyin multiple myeloma显示文摘 | Agnelli L Fabris S Bicciato S et a1 | 2007 | Br J Haematel2007，136，4： | 1 |
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