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| 1 | Micro and Nanofabrication methods to control cell-substrate interactions and cell behavior: A review from the tissue engineering perspective显示文摘Cell-substrate interactions play a crucial role in the design of better biomaterials and integration ofimplants with the tissues. Adhesion is the binding process of the cells to the substrate through interactionsbetween the surface molecules of the cell membrane and the substrate. There are severalfactors that affect cell adhesion including substrate surface chemistry, topography, and stiffness. Thesefactors physically and chemically guide and influence the adhesion strength, spreading, shape and fate ofthe cell. Recently, technological advances enabled us to precisely engineer the geometry and chemistry ofsubstrate surfaces enabling the control of the interaction cells with the substrate. Some of the mostcommonly used surface engineering methods for eliciting the desired cellular responses on biomaterialsare photolithography, electron beam lithography, microcontact printing, and microfluidics. Thesemethods allow production of nano- and micron level substrate features that can control cell adhesion,migration, differentiation, shape of the cells and the nuclei as well as measurement of the forces involvedin such activities. This review aims to summarize the current techniques and associate these techniqueswith cellular responses in order to emphasize the effect of chemistry, dimensions, density and design ofsurface patterns on cell-substrate interactions. We conclude with future projections in the field of cellsubstrateinteractions in the hope of providing an outlook for the future studies. | Menekse Ermis Ezgi Antmen Vasif Hasirci | 2018 | Bioactive Materials2018，3，3： | 13 |
| 2 | Effects of tyrosine kinase inhibitor E7080 and eNOS inhibitor L-NIO on colorectal cancer alone and in combination显示文摘Objective:To investigate the effects of E7080 and N5-(1-iminoethyl)-L-ornithine dihydrochloride(L-NIO)on colorectal cancer alone and in combination.Methods:HT29 colorectal cancer cell line from Sap Institute was used.Real-time cell analysis(xCELLigence system)was performed to determine the effects of E7080 and L-NIO on colorectal cell proliferation.While apoptosis was determined with Annexin V staining,and the effect of agents on angiogenesis was determined with chorioallantoic membrane(CAM)model.Results:We found that E7080 has a strong antiproliferative effect with an half maximum inhibition of concentration(IC50)value of 5.60×10–8mol/L.Also it has been observed that E7080 showed antiangiogenic and apoptotic effects on HT29 colorectal cancer cells.Antiangiogenic scores of E7080 were 1.2,1.0 and 0.6for 100,10 and 1 nmol/L E7080 concentrations,respectively.Furthermore,apoptosis has been detected in71%of HT29 colorectal cancer cells after administration of 100 nmol/L E7080 which may indicate strong apoptotic effect.Meanwhile administration of L-NIO alone did not show any effect,but the combination of E7080 with L-NIO increased the antiproliferative,antiangiogenic and apoptotic effects of E7080.Conclusions:Results of this study indicate that E7080 may be a good choice in treatment of colorectal tumors.Furthermore the increased effects of E7080 when combined with L-NIO raise the possibility to use a lower dose of E7080 and therefore avoid/minimize the side effects observed with E7080. | Ahmet Altun Tijen Kaya Temiz Ezgi Balc Zübeyde Ak n Polat Mustafa Turan | 2013 | Chinese Journal of Cancer Research2013，25，5： | 4 |
| 3 | Effect of transcatheter aortic valve implantation on QT dispersion in patients with aortic stenosis显示文摘BackgroundQT 分散(QTd ) 是室的心律不齐的一个预言者。室的心律不齐是与大动脉的狭窄在病人影响病态和死亡的一个重要因素。外科的大动脉的阀门代替在这个病人组减少了 QTd。然而, transcatheter 的效果在有大动脉的狭窄的病人的 QTd 上的大动脉的阀门培植(TAVI ) 是未知的。这研究的目的是调查 TAVI 的效果在上在有有严重大动脉的狭窄的大动脉的 stenosis.MethodsPatients 的病人,不由于禁止徵候或高外科的风险是外科的大动脉的阀门代替的候选人,的 QTd 在学习被包括。所有病人经历了 electrocardiographic 和 echocardiographic 评估在前,并且在 6 在 TAVI,计算 QTd 和左以后的 th 月室的集体索引(LVMI ).ResultsA 总数 30 病人进入学习(吝啬的年龄 83.2 ±1.0 年,女性 21 和男性 9,吝啬的阀门区域 0.7 ±3 公里 2) 。爱德华兹智慧心阀门, 23 公里(21 个病人) 和 26 公里(9 个病人) ,由 transfemoral,途径在 TAVI 过程被使用。所有 TAVI 过程是成功的。在 6 在 TAVI 以后的 th 月显著地在 TAVI 前与 QTd 和 LVMI 的基线价值相比被减少(73.8 ±4 ms 对 68 ±2 ms, P = 0.001 和 198 ±51 g/m 2 对 184 ±40 g/m 2, P = 0.04,分别地) 。在 QTd 和 LVMI 之间有重要关联(r = 0.646, P <0.001 ).ConclusionsQTd,它诽谤室的心律不齐标记,和 LVMI 显著地在 TAVI 以后被减少过程。TAVI 可以减少在有大动脉的狭窄的病人的室的心律不齐的可能性。 | Hakan Erkan Engin Hatem Mustafa Tank Agac Levent Korkmaz Teyyar Gokdeniz Ahmet Cagrl Aykan Ezgi Kalaycloglu Faruk Boyacl Omer Faruk Clrakoglu Sukru Celik | 2014 | Journal of Geriatric Cardiology2014，11，4： | 3 |
| 4 | Transient acute flaccid paralysis and seizures associated with rotavirus gastroenteritis in a child显示文摘 | Ezgi ~)zalp T ti rkan Aydln-Teke Grin )31 Tantr | 2012 | The Turkish Journal of Pediatrics2012，54，： | 1 |
| 5 | A “silent” course of normotensive scleroderma renal crisis: case report and review of the literature显示文摘 | Hadim Akoglu Gokhan Kadir At?lgan Ramazan Ozturk Ezgi Coskun Yenigun Ipek Is?k Gonul Ali R?za Odabas | 2009 | Rheumatology International2009，，10： | 1 |
| 6 | Real‐time ultrasound guided placement of temporary internal jugular vein catheters: Assessment of technical success and complication rates in nephrology practice显示文摘 | HADIM AKOGLU SERHAN PISKINPASA EZGI C YENIGUN RAMAZAN OZTURK FATIH DEDE ALI R ODABAS | 2012 | Nephrology2012，，7： | 1 |
| 7 | Effects of prochloraz on DNA damage, lipid peroxidation and antioxidant system in vitro显示文摘 | Buket Alpertunga Mehtap Kara Mahmoud Abudayyak Ezgi Oztas Sibel Ozden Gü l ? zhan | 2014 | Toxicology Mechanisms and Methods2014，，4： | 1 |
| 8 | Flurbi- profen in rapid eye movement sleep deprivation induced hyperalgesia显示文摘 | Elif Ezgi Gtirel Keremcan Ural Gtilnur Ozttirk | 2014 | Physiology & Behavior2014，128，： | 1 |
| 9 | An integrated multiob- jective decision making process for supplier selection and order allocation显示文摘 | Ezgi Aktar Demirtas Ozden Ustun | 2008 | Omega2008，36，1： | 1 |
| 10 | 4D printing of polyurethane paint-based composites显示文摘In recent studies,polyurethane has shown multiple properties that make it an excellent candidate material in 4D printing.In this study,we present a simple and inexpensive additive method to print waterborne polyurethane paint-based composites by adding carboxymethyl cellulose(CMC)and silicon oxide(SiO2)nanoparticles to the paint.The first function of CMC and SiO_(2) is to improve rheological properties of the polyurethane paint for making a printable precursor,which improves the printing resolution and enhances additive manufacturability.Second,the composite precursors improve the curing rate of the polyurethane paint without changing its inherited shape memory properties.Third,the printed composite parts shown enhanced mechanical strength compared with that of the parts printed with pure polyurethane.Finally,the 3D printedpolyurethane-CMCandSiO_(2) parts exhibit time-resolved shape transformation upon heat stimulation.To the best of our knowledge,this is the first study of using the polyurethane paint as the precursor for 4D printing,which would open new possibilities in future applications in biomedical engineering,soft robotics and so on. | Jheng-Wun Su Wenxin Gao Khoinguyen Trinh Stuart M.Kenderes Ezgi Tekin Pulatsu Cheng Zhang Alan Whittington Mengshi Lin Jian Lin | 2019 | International Journal of Smart and Nano Materials2019，10，3： | 1 |
| 11 | An integrated multiobjective decisionmaking process for supplier selection and order allocation显示文摘 | Ezgi A D Ozden U | 2006 | The International Journal of Management Science2006，，36： | 1 |
| 12 | An integrated multi-objective decision maki ng process for supplier selection and order allocation显示文摘 | Ezgi A D Ozden U | 2006 | The International J ournal of Management Science2006，，36： | 1 |
| 13 | Numerical analysis of submerged inlets显示文摘 | Ezgi S Taskinoglu Doyle Knight | | 0，，： | 1 |
| 14 | Thermo hydraulic and thermo Economic Performance of a marine heat exchanger on a naval surface ship 显示文摘 | Cuneyt Ezgi Necdet Ozbalta Ibrahim Girgin | 2014 | Applied Thermal Engineering2014，64，1： | 1 |
| 15 | Experimental investigation of a submerged subsonic inletPart Ⅱ显示文摘 | Vasilije J Jovanovic Ezgi S Taskinoglu Doyle D Knight | | 0，，： | 1 |
| 16 | P-wave duration and dispersion in patients with coronary slow flow and its relationship with Thrombolysis in Myocardial Infarction frame count显示文摘 | Sait M. Dogan Nesligul Yildirim Metin Gursurer Mustafa Aydin Ezgi Kalaycioglu Fatih Cam | 2008 | Journal of Electrocardiology2008，，1： | 1 |
| 17 | An integrated multiobjective decision making process for supplier selection and order allocation显示文摘 | Ezgi Aktar Demirtas Ozden ustun | 2008 | Omega2008，36，2： | 1 |
| 18 | An integrated multi-objective decision making process for supplier selection and order allocation 显示文摘 | Ezgi Aktar Demirtas Ozden Ustun | 2008 | OMEGA-International Journal of Management Science2008，36，： | 1 |
| 19 | Virtual reconstruction of archaeological vessels using expert priors and intrinsic differential geometry information 显示文摘 | Cohen F Liu Z Ezgi T | 2012 | Computers & Graphics2012，37，1： | 1 |
| 20 | Ecological dyeing with some plant pulps on woolen yarn and cationized cotton fabric显示文摘 | Meliha Oktav Bulut Ezgi Akar | 2012 | Journal of Cleaner Produciton2012，32，： | 1 |
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