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4篇 您的检索式：作者名="Edith Roth"

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		题名	作者	年代	出处	被引量
	1	Endothelial dysfunction contributes to severe COVID-19 in combination with dysregulated lymphocyte responses and cytokine networks显示文摘The systemic processes involved in the manifestation of life・threatening COVID-19 and in disease recovery are still incompletely understood,despite investigations focusing on the dysregulation of immune responses after SARS-CoV-2 infection.To define hallmarks of severe COVID-19 in acute disease(n=58)and in disease recovery in con valesce nt patie nts(n=28)from Han nover Medical School,we used flow cytometry and proteomics data with unsupervised clustering analyses.In our observational study,we combined analyses of immune cells and cytokine/chemokine networks with endothelial activation and injury.ICU patients displayed an altered immune signature with prolonged lymphopenia but the expansion of granulocytes and plasmablasts along with activated and terminally differentiated T and NK cells and high levels of SARS-CoV-2-specific antibodies.The core signature of seven plasma proteins revealed a highly inflammatory microenvironment in addition to endothelial injury in severe COVID-19.Changes within this sign ature were associated with either disease progression or recovery.In summary,our data suggest that besides a strong inflammatory response,severe COVID-19 is driven by endothelial activation and barrier disruption,whereby recovery depends on the regeneration of the endothelial integrity.	Louisa Ruhl Isabell Pink Jenny F.Kiihne Kerstin Beushausen Jana Keil Stella Christoph Andrea Sauer Lennart Boblitz Julius Schmidt Sascha David Hans-Martin Jack Edith Roth Markus Cornberg Thomas F.Schulz Tobias Welte Marius M.Hoper Christine S.Falk	2022	Signal Transduction and Targeted Therapy2022，7，1：	1
	2	Does the Timing of Esophagectomy After Chemoradiation Affect Outcome?显示文摘	Jae Y. Kim Arlene M. Correa Ara A. Vaporciyan Jack A. Roth Reza J. Mehran Garrett L. Walsh David C. Rice Jaffer A. Ajani Dipen M. Maru Manoop S. Bhutani James Welsh Edith M. Marom Stephen G. Swisher Wayne L. Hofstetter	2012	The Annals of Thoracic Surgery2012，，1：	1
	3	Commingled yarns of surface nanostructured glass and polypropylene filaments for effective composite properties显示文摘	Mader Edith Rothe Christina Shang - Lin Gao	2007	J Mater Sci2007，42，19：	1
	4	Copeptin Improves Early Diagnosis of Acute Myocardial Infarction显示文摘	Till Keller Stergios Tzikas Tanja Zeller Ewa Czyz Lars Lillpopp Francisco M. Ojeda Alexander Roth Christoph Bickel Stephan Baldus Christoph R. Sinning Philipp S. Wild Edith Lubos Dirk Peetz Jan Kunde Oliver Hartmann Andreas Bergmann Felix Post Karl J. Lac	2010	Journal of the American College of Cardiology2010，，19：	1

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