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1Treatment modalities for early gastric cancer显示文摘Different treatment modalities have been proposed in the treatment of early gastric cancer(EGC). Endoscopic resection(ER) is an established treatment that allows curative treatment, in selected cases. In addition, ER allows for an accurate histological staging, which is crucial when deciding on the best treatment option for EGC. Recently, endoscopic mucosal resection(EMR) and endoscopic submucosal dissection(ESD) have become alternatives to surgery in early gastric cancer, mainly in Asian countries. Patients with 'standard' criteria can be successfully treated by EMR techniques. Those who meet 'expanded' criteria may benefit from treatment by ESD, reducing the need for surgery. Standardized ESD training system is imperative to promulgate effective and safe ESD technique to practices with limited expertise. Although endoscopic resection is an option in patients with EGC, surgical treatment continues to be a widespread therapeutic option worldwide. In this review we tried to point out the treatment modalities for early gastric cancer.Jesús Espinel Eugenia Pinedo Vanesa Ojeda Maria Guerra del Rio 2015World Journal of Gastrointestinal Endoscopy2015,7,12:11
2The effect of Saccharomyces cerevisiae on digestion and mortality in the volcano rabbit(Romerolagus diazi)显示文摘An experiment was conducted to evaluate whether supplementation with a probiotic could enhance digestion and reduce mortality in the volcano rabbit in captivity. Two enclosures at Chapultepec Zoo, Mexico(114 individuals) were used in a crossover design(two periods of 60 days) with the following treatments: control group and supplementation with Saccharomyces cerevisiae(2×108 CFU/exhibit/day). Supplementation with the probiotic negatively affected(P<0.01) the digestibility of dry matter, organic matter, neutral detergent fiber(NDF) and energy. Mortality increased(P<0.04) following supplementation with the probiotic(4.26% vs. 8.89%), primarily in the juvenile rabbits. The results indicate that yeast supplementation in the volcano rabbit negatively affects digestion and mortality in captivity.Rogelio Campos-Morales Germán D Mendoza Javier Ojeda Fernando X Plata José A Martínez 2015Journal of Integrative Agriculture2015,14,3:2
3CD4+ T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus/hepatitis C virus-coinfected patients显示文摘AIM To characterize peripheral blood natural killer(NK) cells phenotypes by flow cytometry as potential biomarker of liver fibrosis in human immunodeficiency virus(HIV)/hepatitis C virus(HCV) coinfected patients.METHODS Peripheral mononuclear cells from 24 HIV/HCV(HBVnegative) coinfected and 5 HIV/HCV/HBV seronegative individuals were evaluated. HIV/HCV coinfected patients were divided in to groups: G1, patients with METAVIR F0-F2 and G2, patients with METAVIR F3-F4. NK surface cell staining was performed with: AntiCD3(APC/Cy7), anti-CD56(PE/Cy5), anti-CD57(APC), anti-CD25(PE), anti-CD69(FITC), anti-NKp30(PE), antiNKp46(PE/Cy7), anti-NKG2D(APC), anti-DNAM(FITC); anti-CD62L(PE/Cy7), anti-CCR7(PE), anti-TRAIL(PE), anti-Fas L(PE), anti CD94(FITC). Flow cytometry data acquisition was performed on BD FACSCanto, analyzed using Flow Jo software. Frequency of fluorescence was analyzed for all single markers. Clinical records were reviewed, and epidemiological and clinical data were obtained.RESULTS Samples from 11 patients were included in G1 and from 13 in G2. All patients were on ARV, with undetectable HIV viral load. Liver fibrosis was evaluated by transient elastography in 90% of the patients and with biopsy in 10% of the patients. Mean HCV viral load was(6.18 ± 0.7 log10). Even though, no major significant differences were observed between G1 and G2 regarding NK surface markers, it was found that patients with higher liver fibrosis presented statistically lower percentage of NK cells than individual with low to mild fibrosis and healthy controls(G2: 5.4% ± 2.3%, G1: 12.6% ± 8.2%, P = 0.002 and healthy controls 12.2% ± 2.7%, P = 0.008). It was also found that individuals with higher liver fibrosis presented lower CD4 LT count than those from G1(G2: 521 ± 312 cells/μL, G1: 770 ± 205 cells/μL; P = 0.035).CONCLUSION Higher levels of liver fibrosis were associated with lower percentage of NK cells and LTCD4+ count; and they may serve as noninvasive biomarkers of liver damage.Natalia Laufer Diego Ojeda María Laura Polo Ana Martinez Héctor Pérez Gabriela Turk Pedro Cahn Norberto Walter Zwirner Jorge Quarleri 2017World Journal of Hepatology2017,9,25:2
4Littoral-cell angioma of the spleen:A case report显示文摘Littoral-cell angioma (LCA) is a primary splenic vascular tumor that arises from the normal littoral cells lining the sinus channels of the splenic red pulp. We report a case of LCA of the spleen, which has been infrequently communicated in the literature. A 76-year-old man with a 2-wk history of weight loss, abdominal pain and changes in bowel habits was admitted to our hospital. Imaging studies (CT and MRI) showed multiple lesions in the spleen. Splenectomy was performed. Lining cells were positive for CD31/CD68 markers. Our case was associated with a serrated colonic adenoma. LCA is a benign vascular tumor of the spleen that needs to be included in the differential diagnosis of multiple splenic nodules.ngel Cosme ngel Tejada Luis Bujanda Manuel Vaquero José Luis Elorza Evelia Ojeda Unai Goikoetxea 2007World Journal of Gastroenterology2007,13,48:2
5Combined partial arthroscopic synovectomy and radiation therapy for diffuse pigmented villonodular synovitis of the knee显示文摘Carlos E.Rodriguez Blanco Heriberto Ojeda Leon Todd B Guthrie 2001Arthroscopy: The Journal of Arthroscopic and Related Surgery2001,,5:2
6Generation of spinal motor neurons from human fetal brain-derived neural stem cells: role of basic fibroblast growth factor 显示文摘Jordan PM Ojeda LD Thonhoff JR 2009J Neurosci Res2009,87,2:1
7Undernutration,puberty and development of estrogen positive feedback in the female rat显示文摘Ronnekleiv OK Ojeda SR McCann SM 1978Biol Reprod1978,19,:1
8Reaction mechanism and theological properties of polypropylene irradiated under various atmospheres显示文摘Lugao AB Hutzler B Ojeda T 2000Radiation Physics and Chemistry2000,57,3:1
9Molecular characterization of FOX- 4, a new AmpC-type plasmid-mediated beta-lactamase from an Escherichia coli strain isolated in Spain 显示文摘Bou G Oliver A Ojeda M 2000Antimicrob Agents Chemother2000,44,9:1
10Synthesis of sugar - based chelating surfactants for metal removal from wastewater 显示文摘FERLIN N GRASSI D OJEDA C 2008Carbohydrate Research2008,343,5:1
11Malassezia globosa as the causative agent of pityfiasis vcrsicolor显示文摘Crespo Erchiga V Ojeda Martos A Vera Casano A 2000Br J Dermatol2000,143,4:1
12Heuristic reduction of gyro drift in gyro-based vehicle tracking显示文摘BORENSTEIN J OJEDA L 2009Sensors & Com- mand Control Communications & Intelligence Technolo- gies for Homeland Security & Homeland Defense VIII2009,7305,:1
13Role of neurotro- pbic factors in early ovarian development 显示文摘Dissen G A Garcia-Rudaz C Ojeda S R 2009Semin Reprod Med2009,27,1:1
14Development of high power VRLA batteries using novel materials and processes 显示文摘Soria M L Valenciano J Ojeda A 2003Journal of power sources2003,116,1:1
15Synthesis of new chelating surfactants from octyl d - glucopyranosiduronic acid and amino acids for metal flotation 显示文摘FERLIN N GRASSI D OJEDA C 2010Carbohydrate Research2010,345,5:1
16Accurate Mobile Robot Dead-reckoning with a Precision-calibrated Fiber Optic Gyroscope显示文摘Chung H Ojeda L Borenstein J 2001IEEE Transaction on Robotics and Automation2001,17,1:1
17Verbal fluency in schizophrenia: dose cognitive performance reflect the same under显示文摘Ojeda N Scinchez P Pena J 2010J Nerv Ment Dis2010,198,4:1
18Primary adenocarcinoma of the urinary bladder: our experience 显示文摘Romero Otero J Duarte Ojeda JM Cruceyra Betriu G 2005Actas Urol Esp2005,29,3:1
19Glossitis with linear lesions: an early sign of vitamin B12 deficiency显示文摘Graells J Ojeda RM Muniesa C et a/ 2009J Am Acad Dermatol2009,60,3:1
20Circulating in flammatory mediators during start of fever in differential diagnosis of gram-negative and gram-positive infections in leucopenia rats显示文摘Tavares E Maldonado R Ojeda ML 2005Cline Diane Lab lmmunol2005,12,:1
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