|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Treatment responses in Asians and Caucasians with chronic hepatitis C infection显示文摘AIM:To conduct a multicentre retrospective review of virological response rates in Asians infected with genotype 1 chronic hepatitis C(CHC) treated with combination interferon and ribavirin and then to compare their responses to that among Caucasians.METHODS:Asian patients infected with genotype 1 CHC treated at 4 Australian centres between 2001 to 2005 were identified through hospital databases.Baseline demographic characteristics,biochemical,virological and histological data and details of treatment were collected.Sustained virological responses(SVR) in this cohort were then compared to that in Caucasian subjects,matched by genotype,age,gender and the stage of hepatic fibrosis.RESULTS:A total of 108 Asians with genotype 1 CHC were identified.The end of treatment response(ETR) for the cohort was 79% while the SVR was 67%.Due to the relatively advanced age of the Asian cohort,only sixty-four subjects could be matched with Caucasians.The ETR among matched Asians and Caucasians was 81% and 56% respectively(P=0.003),while the SVR rates were 73% and 36%(P <0.001) respectively.This difference remained significant after adjusting for other predictive variables. | Kenneth K Yan Marianne Guirgis Amany Zekry Thuy Dinh Anouk Dev Jacob George Alice Lee | 2008 | World Journal of Gastroenterology2008，14，21： | 12 |
| 2 | 剖宫产再孕的妇女孕期B超监测下剖宫产瘢痕形态学改变显示文摘目的:通过B超监测评价剖宫产再孕的孕妇在整个妊娠过程中剖宫产瘢痕处的形态改变,并评价最后的分娩结局。方法:应用阴道超声观察320例有剖宫产史并再次妊娠的妇女怀孕11~13周、19~21周以及32~34周时剖宫产瘢痕的变化,主要测量剖宫产瘢痕处子宫肌层的厚度变化。结果:在320例孕妇中,284例发现剖宫产瘢痕的宽度、长度及厚度均发生改变,比例达到88.7%,瘢痕的长度和宽度明显增大,瘢痕的厚度明显变薄。2例孕妇因剖宫产瘢痕处子宫肌层发生破裂而终止妊娠,这2例病例,B超监测瘢痕处子宫肌层厚度为0.5mm,整个孕期减少了2.7mm、2.5mm。结论:通过观察,建立了相关的B超参考数据,并证明了剖宫产瘢痕在下一次妊娠中会发生形态学上的改变。菲薄的瘢痕处肌层厚度以及该处厚度的快速减少是剖宫产瘢痕破裂的先兆,在剖宫产再孕产妇的孕期监测过程中,瘢痕处肌层厚度的快速改变是提示剖宫产瘢痕破裂的潜在预警信号。这对防止剖宫产再孕的孕妇发生子宫破裂具有重要的意义。 | 冯颖 李坚 段华 陈雁鸣 Sooranna Dev Ruilian Chen | 2013 | 中国医学创新2013，10，23： | 12 |
| 3 | Analysis on Critical Success Factors for Agile Manufacturing Evaluation in Original Equipment Manufacturing Industry-An AHP Approach显示文摘Manufacturing industries are facing challenges in the implementation of agile manufacturing in their products and processes.Agility is widely accepted as a new competitive concept in the manufacturing sector in fulfilling varying customer demand. Thus,evaluation of agile manufacturing in industries has become a necessity. The success of an organisation depends on its ability to manage finding the critical success factors and give them special and continued attention in order to bring about high performance. This paper proposes a set of critical success factors(CSFs) for evaluating agile manufacturing considered appropriate for the manufacturing sector.The analytical hierarchy process(AHP) method is applied for prioritizing the success factors, by summarizing the opinions of experts. It is believed that the proposed CSFs enable and assist manufacturing industries to achieve a higher performance in agile manufacturing so as to increase competitiveness. | C Ajay Guru Dev V S Senthil Kumar | 2016 | Chinese Journal of Mechanical Engineering2016，29，5： | 7 |
| 4 | Characteristics of microbial community functional structure of a biological coking wastewater treatment system显示文摘Nitrogenous heterocyclic compounds are key pollutants in coking wastewater; however, the functional potential of microbial communities for biodegradation of such contaminants during biological treatment is still elusive. Herein, a high throughput functional gene array(Geo Chip 5.0)in combination with Illumina Hi Seq2500 sequencing was used to compare and characterize the microbial community functional structure in a long run(500 days) bench scale bioreactor treating coking wastewater, with a control system treating synthetic wastewater. Despite the inhibitory toxic pollutants, Geo Chip 5.0 detected almost all key functional gene(average61,940 genes) categories in the coking wastewater sludge. With higher abundance, aromatic ring cleavage dioxygenase genes including multi ring1,2 diox; one ring2,3 diox; catechol represented significant functional potential for degradation of aromatic pollutants which was further confirmed by Illumina Hi Seq2500 analysis results. Response ratio analysis revealed that three nitrogenous compound degrading genes-nbz A(nitro-aromatics), tdn B(aniline), and scn ABC(thiocyanate) were unique for coking wastewater treatment, which might be strong cause to increase ammonia level during the aerobic process. Additionally, Hi Seq2500 elucidated carbozole and isoquinoline degradation genes in the system. These findings expanded our understanding on functional potential of microbial communities to remove organic nitrogenous pollutants;hence it will be useful in optimization strategies for biological treatment of coking wastewater. | Dev Raj Joshi Yu Zhang Hong Zhang Yingxin Gao Min Yang | 2018 | Journal of Environmental Sciences2018，30，1： | 6 |
| 5 | Mechanisms of triglyceride metabolism in patients with bile acid diarrhea显示文摘Bile acids(BAs) are essential for the absorption of lipids. BA synthesis is inhibited through intestinal farnesoid X receptor(FXR) activity. BA sequestration is known to influence BA metabolism and control serum lipid concentrations. Animal data has demonstrated a regulatory role for the FXR in triglyceride metabolism. FXR inhibits hepatic lipogenesis by inhibiting the expression of sterol regulatory element binding protein 1c via small heterodimer primer activity. Conversely, FXR promotes free fatty acids oxidation by inducing the expression of peroxisome proliferator-activated receptor α. FXR can reduce the expression of microsomal triglyceride transfer protein, which regulates the assembly of very low-density lipoproteins(VLDL). FXR activation in turn promotes the clearance of circulating triglycerides by inducing apolipoprotein C-Ⅱ, very low-density lipoproteins receptor(VLDL-R) and the expression of Syndecan-1 together with the repression of apolipoprotein C-Ⅲ, which increases lipoprotein lipase activity. There is currently minimal clinical data on triglyceride metabolism in patients with bile acid diarrhoea(BAD). Emerging data suggests that a third of patients with BAD have hypertriglyceridemia. Further research is required to establish the risk of hypertriglyceridaemia in patients with BAD and elicit the mechanisms behind this, allowing for targeted treatment. | Nidhi Midhu Sagar Michael McFarlane Chuka Nwokolo Karna Dev Bardhan Ramesh Pulendran Arasaradnam | 2016 | World Journal of Gastroenterology2016，22，30： | 5 |
| 6 | A systematic investigation of secondary phase dissolution in Mg-Sn alloys显示文摘As-cast Mg-Sn alloys(3,6,and 9 wt%Sn)were solution treated at 653,703 and 753 K(380,430 and 480℃)for 1,4,8,12 and 24 h to determine the variation of secondary phase with respect to Sn content,temperature and time.Mg-3 wt%Sn exhibits Mg2Sn dissolution at all solution treatment temperatures whereas Mg-6 and 9 wt%Sn alloy displays Mg2Sn reprecipitation and dissolution depending on the heat treatment temperature.In addition,a combined mathematical model that predicts the secondary phase dissolution and solute redistribution as a function of temperature and time is presented in this work.This model is a significant improvement compared to the previous studies where the dissolution and homogenization processes are considered independently.The effect of grain size and solute mobility upon the dissolution and homogenization kinetics is discussed as well. | Arushi Dev Niladri Naskar Nishant Kumar Ashutosh Jena Manas Paliwal | 2019 | Journal of Magnesium and Alloys2019，7，4： | 5 |
| 7 | A survey on future research about electron beam welding for aerospace applications显示文摘Electron beam welding plays an important role in the aerospace industry where components like sensors,gears,actuators and air frames used in aircraft and rocket engines were welded using this technique.Welding is normally performed in a vacuum to avoid the scatter of electron due to the presence of gas molecules in the atmosphere and hence electron beam welding process provides the greater results.But still joining of dissimilar metals is challenging.This paper represents review of process,generation and distribution of heat source various input parameters,materials,microstructure,mechanical strength and the possibilities of joining dissimilar metals using electron beam welding. | Ajith Raj Rajendran Dev Anand Manoharan | 2018 | China Welding2018，27，1： | 4 |
| 8 | 税收增额融资制度(TIF)是否能提高城市产业和物业价值?显示文摘本文研究税收增额融资制度(TIF)对芝加哥产业物业价值的影响。研究发现,在芝加哥位于混合用途类TIF区(如商住混合区)的工业地块价值高于非TIF区类似工业地块的价值;然而,在纯粹工业TIF区的地块价值则不高于、甚至有时还明显地低于不在TIF区的类似地块。 | Rachel Weber Saurav Dev Bhatta David Merriman 胡忆东 王兰 | 2006 | 国外城市规划2006，21，4： | 4 |
| 9 | Role of angiotensin converting enzyme and angiotensinogen gene polymorphisms in angiotensin converting enzyme inhibitor-mediated antiproteinuric action in type 2 diabetic nephropathy patients显示文摘AIM To investigate the role of genetic variants of angiotensin converting enzyme(ACE) and angiotensinogen(AGT) genes in the antiproteinuric efficacy of ACE inhibitor therapy in diabetic nephropathy(DN) patients.METHODS In the present study, 270 type 2 diabetes mellitus patients with nephropathy were enrolled and treated with ACE inhibitor(ramipril) and followed at 6 mo for renal function and albumin excretion by estimating serum creatinine, end stage renal disease, and albumin/creatinine ratio(ACR) in urine. Genotyping of ACE I/D and AGT M235 T polymorphisms were performed by using primer specific polymerase chain reaction(PCR) and PCR-RFLP techniques, respectively. RESULTS Forty-eight percent of DN patients(responders) benefited with respect to proteinuria from ACE inhibitor therapy at 6 mo follow-up. A significant reduction in ACR was observed after 6 mo treatment with ACE inhibitor irrespective of whether DN patients were micro-albuminuric(≥ 30 and < 300 mg/g creatinine) or macro-albuminuric(≥ 300 mg/g creatinine) at the time of enrollment. However, macro-albuminuric patients(55%) showed better response to therapy. A reduction in urinary ACR was found independent of genotypes of ACE I/D and AGT M235 T polymorphisms although macro-albuminuric patients having TT genotype showed statistically insignificant increased response(72%). CONCLUSION ACE inhibitor therapy reduced urinary ACR by ≥ 30% in 50% of DN patients and the response is independent of ACE I/D and AGT M235 T polymorphisms. | Neerja Aggarwal Pawan Kumar Kare Parul Varshney Om Prakash Kalra Sri Venkata Madhu Basu Dev Banerjee Anil Yadav Alpana Raizada Ashok Kumar Tripathi | 2017 | World Journal of Diabetes2017，8，3： | 4 |
| 10 | Effect of Low Level Subchronic Microwave Radiation on Rat Brain显示文摘Objective The present study was designed to investigate the effects of subchronic low level microwave radiation(MWR) on cognitive function,heat shock protein 70(HSP70) level and DNA damage in brain of Fischer rats.Methods Experiments were performed on male Fischer rats exposed to microwave radiation for 90 days at three different frequencies: 900,1800,and 2450 MHz.Animals were divided into 4 groups: Group I: Sham exposed,Group II: animals exposed to microwave radiation at 900 MHz and specific absorption rate(SAR) 5.953 × 10-4 W/kg,Group III: animals exposed to 1800 MHz at SAR 5.835 × 10-4 W/kg and Group IV: animals exposed to 2450 MHz at SAR 6.672 × 10-4 W/kg.All the animals were tested for cognitive function using elevated plus maze and Morris water maze at the end of the exposure period and subsequently sacrificed to collect brain tissues.HSP70 levels were estimated by ELISA and DNA damage was assessed using alkaline comet assay.Results Microwave exposure at 900-2450 MHz with SAR values as mentioned above lead to decline in cognitive function,increase in HSP70 level and DNA damage in brain.Conclusion The results of the present study suggest that low level microwave exposure at frequencies 900,1800,and 2450 MHz may lead to hazardous effects on brain. | Pravin Suryakantrao Deshmukh Kanu Megha Namita Nasare Basu Dev Banerjee Rafat Sultana Ahmed Mahesh Pandurang Abegaonkar Ashok Kumar Tripathi Pramod Kumari Mediratta | 2016 | Biomedical and Environmental Sciences2016，29，12： | 4 |
| 11 | Effect of heat treatment conditions on the passivation behavior of WE43CMg-Y-Nd alloy in chloride containing alkaline environments显示文摘Mg–Y–Nd alloy(WE43C or Elektron 43)is a heat treatable magnesium wrought alloy that can be used up to 250 ℃ for aerospace application.This alloy has excellent mechanical properties(UTS:up to 345 MPa at room temperature)and improved corrosion resistance.Electrochemical passivation studies were conducted on this alloy under different heat treatment conditions in 0.1 M NaOH solution with the addition of chloride from 0 to 1000 ppm.The passive potential range typically extended to more than 1.5 VAg/AgCl.The transpassive potential was not dependent on the heat treatment condition of the alloy when the chloride concentration increased up to 500 ppm.However,pitting protection potential varied with the heat treatment condition when the chloride addition was 500 ppm or more.The specimen surface was analyzed using scanning electron microscopy(SEM),X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS),and Raman spectroscopy to understand the passivation behavior of this alloy.The passivated surface of the WE43C specimens indicated that the surface layer consisted of MgO,Mg(OH)_(2),and rare earth oxide phases,and the heat treatment conditions did not significantly affect the composition of the surface film. | Jakraphan Ninlachart Zachary Karmiol Dev Chidambaram Krishnan SRaja | 2017 | Journal of Magnesium and Alloys2017，5，2： | 3 |
| 12 | STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation显示文摘 | Hazel Tye Catherine L. Kennedy Meri Najdovska Louise McLeod William McCormack Norman Hughes Anouk Dev William Sievert Chia Huey Ooi Tomo-o Ishikawa Hiroko Oshima Prithi S. Bhathal Andrew E. Parker Masanobu Oshima Patrick Tan Brendan J. Jenkins | 2012 | Cancer Cell2012，，4： | 3 |
| 13 | Staining for p53 and Ki-67 increases the sensitivity of EUS-FNA to detect pancreatic malignancy显示文摘AIM:To investigate whether tumor marker staining can improve the sensitivity of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)to diagnose pancreatic malignancy. METHODS:Patients who underwent EUS-FNA were retrospectively identified.Each EUS-FNA specimen was evaluated by routine cytology and stained for tumor markers p53,Ki-67,carcinoembryonic antigen(CEA) and CA19-9.Sensitivity,specificity,positive and negative predictive values(PPV and NPV),and positive and negative likelihood ratios(PLR and NLR)were calculated in order to evaluate the performance of each test to detect malignancy. RESULTS:Sixty-one specimens had complete sets of stains,yielding 49 and 12 specimens from pancreatic adenocarcinomas and benign pancreatic lesions due to pancreatitis,respectively.Cytology alone had sensitivity and specificity of 41%and 100%to detect malignancy, respectively.In 46%of the specimens,routine cytology alone was deemed indeterminate.The addition of either p53 or Ki-67 increased the sensitivity to 51%and 53%,respectively,with perfect specificity,PPV and PLR (100%,100%and infinite).Both stains in combination increased the sensitivity to 57%.While additional staining with CEA and CA19-9 further increased the sensitivity to 86%,the specificity,PPV and PLR were significantly reduced(at minimum 42%,84%and 1,respectively).Markers in all combinations performed poorly as a negative test(NPV 26%to 47%,and NLR 0.27 and 0.70).CONCLUSION:Immunohistochemical staining for p53 and Ki-67 can improve the sensitivity of EUS-FNA to diagnose pancreatic adenocarcinoma. | Alexander W Jahng Sonya Reicher David Chung Donna Varela Rahul Chhablani Anil Dev Binh Pham Jose Nieto Rose J Venegas Samuel W French Bruce E Stabile Viktor E Eysselein | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，11： | 3 |
| 14 | 美国退伍军人医院前列腺癌粒子植入医疗不良事件介绍显示文摘放射性粒子植入作为早期前列腺癌的标准治疗手段,在美国已广泛开展。美国近距离治疗协会及美国医学物理学家协会有明确的指南来加以规范,但是仍有部分医院不能按照指南要求植入粒子,导致部分患者出现严重并发症。本文调研了美国放射性粒子植入相关医疗事件,对美国2002年以来发生的粒子植入医疗事件进行了梳理,分析其发生的原因,提出相应的解决方案,为我国粒子植入从业人员提供参考,以防类似事件发生,保障粒子植入术的健康发展。 | 张宏涛 王泽阳 底学敏 于慧敏 高贞 隋爱霞 王娟 Devjoy Dev | 2017 | 中华放射医学与防护杂志2017，37，10： | 3 |
| 15 | Aberrant promoter methylation of p16 in colorectal adenocarcinoma in North Indian patients显示文摘AIM:To investigate p16 gene methylation and its expression in 30 patients with sporadic colorectal adenocarcinoma in a North Indian population. METHODS:Methylation specific polymerase chain reaction was used to detect p16 gene methylation and immunohistochemistry was used to study the p16 expression in 30 sporadic colorectal tumors as well as adjoining and normal tissue specimens.RESULTS:Aberrant promoter methylation of p16 gene was detected in 12(40%)tumor specimens,whereas no promoter methylation was observed in adjoining and normal tissue.Immunohistochemistry showed expression of p16 protein in 26(86.6%)colorectal tumors whereas complete loss of expression was seen in 4(13.3%)and reduced expression was observed in 12(40%)tumors. In the adjoining mucosa,expression of p16 was in 11 (36.6%)whereas no clear positivity for p16 protein was seen in normal tissue.There was a significant difference in the expression of p16 protein in tumor tissue and adjoining mucosa(P<0.001).The methylation of the p16 gene had a significant effect on the expression of p16 protein(P=0.021).There was a significant association of methylation of p16 gene with the tumor size (P=0.015)and of the loss/reduced expression of p16 protein with the proximal site of the tumor(P=0.047). Promoter methylation and expression of p16 had no relation with the survival of the patients(P>0.05). CONCLUSION:Our study demonstrated that promoter hypermethylation of the p16 gene results in loss/reduced expression of p16 protein and this loss/reduced expression may contribute to tumor enlargement. | Pooja Malhotra Rakesh Kochhar Kim Vaiphei Jai Dev Wig Safrun Mahmood | 2010 | World Journal of Gastrointestinal Oncology2010，2，7： | 2 |
| 16 | Urban Modification of Thunderstorms: An Observational Storm Climatology and Model Case Study for the Indianapolis Urban Region*显示文摘 | Niyogi Dev Pyle Patrick Lei Ming Arya S Pal Kishtawal Chandra M Shepherd Marshall Chen Fei Wolfe Brian | 2011 | Journal of Applied Meteorology and Climatology2011，，5： | 2 |
| 17 | Does corporate social responsibility affect the cost of capital?显示文摘 | Sadok El Ghoul Omrane Guedhami Chuck C.Y. Kwok Dev R. Mishra | 2011 | Journal of Banking and Finance2011，，9： | 2 |
| 18 | Decent work and work life quality in Nepal: an observation显示文摘 | Dev Raj Adhikari Katsuhiko Hirasawa Yutaka Takakubo Dhruba Lal Pandey | 2011 | Employee Relations2011，，1： | 2 |
| 19 | IL 28 B genotype is not useful for predicting treatment outcome in A sian chronic hepatitis B patients treated with pegylated interferon‐α显示文摘 | Jacinta A Holmes Tin Nguyen Dilip Ratnam Neel M Heerasing Jane V Tehan Sara Bonanzinga Anouk Dev Sally Bell Stephen Pianko Robert Chen Kumar Visvanathan Rachel Hammond David Iser Ferry Rusli William Sievert Paul V Desmond D Scott Bowden Alexander J Thomps | 2013 | J Gastroenterol Hepatol2013，，5： | 2 |
| 20 | Soil texture classification using multi class support vector machine显示文摘The objective of this study is to process the soil images to generate a digital soil classification system for rural farmers at low cost.Soil texture is the main factor to be considered before doing cultivation.It affects the crop selection and regulates the water transmission property.The conventional hydrometer method determines the percentage of sand,silt,and clay present in a soil sample.This method is very cost and time-consuming process.In this approach,we collect 50 soil samples from the different region of west Guwahati,Assam,India.The samples are photographed under a constant light condition using an Android mobile of 13 MP cameras.The fraction of sand,silt,and clay of the soil samples are determined using the hydrometer test.The result of the hydrometer test is processed with the United State Department of Agriculture soil classification triangle for the final soil classification.Soil images are processed through the different stages like pre-processing of soil images for image enhancement,extracting the region of interest for segmentation and the texture analysis for feature vector.The feature vector is calculated from the Hue,Saturation,and Value(HSV)histogram,color moments,color auto Correlogram,Gabor wavelets,and discrete wavelet transform.Finally,Support Vector Machine classifier is used to classify the soil images using linear kernel.The proposed method gives an average of 91.37%accuracy for all the soil samples and the result is nearly the same with the United State Department of Agriculture soil classification. | Utpal Barman Ridip Dev Choudhury | 2020 | Information Processing in Agriculture2020，7，2： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员