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| 1 | 美国临床肿瘤学会IV期非小细胞肺癌化疗的临床实践指南更新显示文摘本文旨在为IV期非小细胞肺癌患者的治疗提供更新版推荐。本文资料检索源自2002年以来公布的相关随机试验文献。此指南范围限于化疗与生物治疗。更新委员会对这些文献进行了总结并提供了推荐更新。162篇文献符合标准被纳入参考。本推荐基于可改善总生存期的治疗方法。仅改善无进展生存期的治疗方法推动了对毒性及生存质量的监测。对于体力状态评分为0分或1分患者的一线治疗,可推荐以铂类为基础的细胞毒性药物的两药联用。对铂类治疗有禁忌的患者,可采用非铂类细胞毒性两药联合。对于体力状态评分为2分的患者,单一细胞毒性药物即可。对于疾病进展或经过4个周期的治疗仍对治疗无反应的患者,应停止一线细胞毒性化疗。即使在6个周期后患者对治疗仍有反应,亦应停止两药细胞毒性化疗。对于伴有明确的表皮生长因子受体(epidermal growth factor receptor,EGFR)突变的患者,可推荐一线采用吉非替尼治疗;对于EGFR突变为阴性或不明确的患者,细胞毒性化疗更佳。除具有特定临床特征的患者外,可推荐贝伐单抗与卡铂-紫杉醇联用。对于通过免疫组化证实EGFR阳性的肿瘤患者,可推荐西妥昔单抗与顺铂-长春瑞滨联用。多西紫杉醇、厄洛替尼、吉非替尼或培美曲塞被推荐作为二线治疗。对于未曾接受过厄洛替尼或吉非替尼治疗的患者,可推荐厄洛替尼作为三线治疗。现有数据不足以推荐常规三线采用细胞毒性药物。已有的证据也不足以推荐常规应用分子标记物选择化疗。 | Christopher G. AZZOLI Sherman Baker JR Sarah TEMIN William PAO Timothy ALIFF Julie BRAHMER David H. JOHNSON Janessa L. LASKIN Gregory MASTERS Daniel MILTON Luke NORDQUIST David G. PFISTER Steven PIANTADOSI Joan H. SCHILLER Reily SMITH Thomas J. SMITH John R. STRAWN David TRENT Giuseppe GIACCONE 丁燕(翻译) 南娟(翻译) 刘谦(翻译) 周清华(校对) 陈军(校对) | 2010 | 中国肺癌杂志2010，13，3： | 43 |
| 2 | 意义建构:博物馆最佳传播实践的探索显示文摘过去几十年的博物馆研究和博物馆专业人员实践探索了博物馆传播的关键原则。博物馆展览建设有策划、设计、施工三个阶段。阐释策划阶段要弄清楚为什么要做这个项目,目标观众是谁,主题是什么,展览的背景情况是什么。阐释设计阶段就要了解展览内容,进行分众传播,具有可达性和真实性,而最核心原则是激发、关联和揭示。施工是实现一个高质量博物馆展览的最后阶段。这些阐释策划、阐释设计、内容创意和展览实施中的规范和标准是博物馆创建世界级展览最有效的方法,也是和观众沟通的有效手段。 | David Masters 许捷 | 2017 | 东南文化2017，，4： | 15 |
| 3 | Season of burn influences fire behavior and fuel consumption in restored shortleaf pine-grassland communities 显示文摘 | Jeffrey C Sparks Ronald E Masters David M Engle | 2002 | Restoration Ecology2002，10，4： | 1 |
| 4 | Season of burn influences fire behavior and fuel consumption in restored shortleaf pine - grassland communities 显示文摘 | Jeffrey C Sparks Ronald E Masters David M Engle | 2002 | Restoration Ecology2002，10，4： | 1 |
| 5 | Gefitinib Versus Placebo in Completely Resected Non–Small-Cell Lung Cancer: Results of the NCIC CTG BR19 Study显示文摘 | Glenwood D. Goss Chris O’Callaghan Ian Lorimer Ming-Sound Tsao Gregory A. Masters James Jett Martin J. Edelman Rogerio Lilenbaum Hak Choy Fadlo Khuri Katherine Pisters David Gandara Kemp Kernstine Charles Butts Jonathan Noble Thomas A. Hensing Kendrith Ro | 2013 | Journal of Clinical Oncology2013，，27： | 1 |
| 6 | The association of A?2 amyloid and composite cognitive measures in healthy older adults and MCI显示文摘 | Karra D. Harrington Yen Ying Lim Kathryn A. Ellis Carly Copolov David Darby Michael Weinborn David Ames Ralph N. Martins Greg Savage Cassandra Szoeke Christopher Rowe Victor L. Villemagne Colin L. Masters Paul Maruff | 2013 | International Psychogeriatrics2013，，10： | 1 |
| 7 | Plasma Amyloid β 42 and Amyloid β 40 Levels Are Associated With Early Cognitive Dysfunction After Cardiac Surgery显示文摘 | Lisbeth A. Evered Brendan S. Silbert David A. Scott Paul Maruff Katrina M. Laughton Irene Volitakis Tiffany Cowie Robert A. Cherny Colin L. Masters Qiao-Xin Li | 2009 | The Annals of Thoracic Surgery2009，，5： | 1 |
| 8 | Too Frail for Surgery?: Initial Results of a Large Multidisciplinary Prospective Study Examining Pre-operative Variables Predictive of Poor Surgical Outcomes显示文摘 | Louis M. Revenig Daniel J. Canter Maxwell D. Taylor Caroline Tai John F. Sweeney Juan M. Sarmiento David A. Kooby Shishir K. Maithel Viraj A. Master Kenneth Ogan | 2013 | Journal of the American College of Surgeons2013，，： | 1 |
| 9 | Species Richness and Patterns of Invasion in Plants, Birds, and Fishes in the United States*显示文摘 | Thomas J. Stohlgren David Barnett Curtis Flather Pam Fuller Bruce Peterjohn John Kartesz Lawrence L. Master | 2006 | Biological Invasions2006，，3： | 1 |
| 10 | Plasma Amyloid β 42 and Amyloid β 40 Levels Are Associated With Early Cognitive Dysfunction After Cardiac Surgery显示文摘 | Lisbeth A. Evered Brendan S. Silbert David A. Scott Paul Maruff Katrina M. Laughton Irene Volitakis Tiffany Cowie Robert A. Cherny Colin L. Masters Qiao-Xin Li | 2009 | The Annals of Thoracic Surgery2009，，： | 1 |
| 11 | Digital Transformation in Morocco:Challenges and Perspectives显示文摘In the public administration,the adoption of digital transformation of processes and services is becoming more widespread,and its implementation requires significant resources to address the strategic,financial,and human challenges.The slow and dependent digital transformation is mostly reliant on organizational culture and the acceptance of the many actors for the adoption of digital procedures.Since the 1990s,the Moroccan government has launched several strategies and initiatives related to the digital transformation of public administration.In contrast to the expectations of the administration,the nation has experienced a gap in the effectiveness of the reforms.International e-government indicators showed that Morocco rose from 82 in 2014 to 110 in 2018,and then it gained four places in 2020.With the COVID-19 health crisis,it turned out that the digital transformation of public administration is becoming more than ever a necessity of the first order,with the aim of improving user access to public services.This article introduces the various efforts made by the Kingdom of Morocco in terms of digital transformation,then presents various weaknesses associated with the results of this project,and finally gives some indications through new references.The new perspective of digital transformation mainly focused on new management of digitizing policy,training of professional human resources,and generalization of access to digital infrastructure. | Mohammed Anouar Elhazziti David Alexandre Correia Ferraz Elhabib Elazzouzi Mohamed Master João Salis Gomes | 2023 | Journal of US-China Public Administration2023，20，2： | 0 |
| 12 | Multi-Material ALE with AMR for Modeling Hot Plasmas and Cold Fragmenting Materials显示文摘We have developed a new 3D multi-physics multi-material code,ALE-AMR,which combines Arbitrary Lagrangian Eulerian(ALE) hydrodynamics with Adaptive Mesh Refinement(AMR) to connect the continuum to the microstructural regimes.The code is unique in its ability to model hot radiating plasmas and cold fragmenting solids.New numerical techniques were developed for many of the physics packages to work efficiently on a dynamically moving and adapting mesh.We use interface reconstruction based on volume fractions of the material components within mixed zones and reconstruct interfaces as needed.This interface reconstruction model is also used for void coalescence and fragmentation.A flexible strength/failure framework allows for pluggable material models,which may require material history arrays to determine the level of accumulated damage or the evolving yield stress in J2 plasticity models.For some applications laser rays are propagating through a virtual composite mesh consisting of the finest resolution representation of the modeled space.A new 2nd order accurate diffusion solver has been implemented for the thermal conduction and radiation transport packages.One application area is the modeling of laser/target effects including debris/shrapnel generation.Other application areas include warm dense matter,EUV lithography,and material wall interactions for fusion devices. | Alice KONIGES Nathan MASTERS Aaron FISHER David EDER Wangyi LIU Robert ANDERSON David BENSON Andrea BERTOZZI | 2015 | Plasma Science and Technology2015，17，2： | 0 |
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