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| 1 | 循证指南:弥散和灌注MRI在急性缺血性卒中诊断中的作用美国神经病学学会治疗和技术评价委员会的报告显示文摘目的 评价弥散加权成像(diffusion-weighted imaging,DWI)和灌注加权成像(perfusionweighted imaging PWI)在急性缺血性卒中患者诊断中应用的证据.方法 对1966年至2008年1月期间有关DWI和PWI诊断和预后价值的文献进行系统分析.结果和推荐 对于发病12 h内的急性缺血性卒中的诊断,DWI已被确认为有效的评价手段,且其诊断价值应高于非增强CT.为了最准确地诊断急性缺血性卒中,应进行DWI(A级推荐);然而,在疑似急性卒中患者的总体样本中,DWI诊断缺血性卒中的敏感性并不完美.DWI诊断脑出血的准确性不在本指南的范围之内.根据Ⅱ级和Ⅲ级证据,基线DWI体积可预测前循环卒中的基线卒中严重程度(B级推荐),但不能预测椎基底动脉系统卒中的基线卒中严重程度(C级推荐).基线DWI病变体积可预测(最终)梗死体积(B级推荐),并且有可能预测早期和远期临床转归(C级推荐).与DWI相比,基线PWI体积预测基线卒中严重程度的价值较小(C级推荐).尚无足够的证据支持或反对PWI在急性缺血性卒中诊断中的价值(U级推荐). | P.D. Schellinger R.N. Bryan L.R. Caplan J.A. Detre R.R. Edelman C. Jaigobin C.S. Kidwell J.P. Mohr M. Sloan A.G. Sorensen S. Warach 章娟娟(译) 王国颖(译) 汪凯(译) | 2010 | 国际脑血管病杂志2010，18，11： | 38 |
| 2 | CYFRA 21-1 as a Prognostic and Predictive Marker in Advanced Non–Small-Cell Lung Cancer in a Prospective Trial: CALGB 150304显示文摘 | Martin J. Edelman Lydia Hodgson Paula Y. Rosenblatt Robert H. Christenson Everett E. Vokes Xiaofei Wang Robert Kratzke | 2012 | Journal of Thoracic Oncology2012，，4： | 3 |
| 3 | 可靠性维修实施案例研究显示文摘以可靠性为中心的维修(RCM)从本质上讲是一个优化维修的方法,用于确定所有系统或资产的维修活动,使其获得最优的性能。RCM广泛应用于各工业部门,自从它诞生以来就被认为是一种有效的维修方法。然而,在企业中实施RCM时还存在若干问题需要解决。对大型水电公司实施RCM时出现的或潜在的一些问题研究发现,RCM的成功实施依赖以下因素所有相关员工的认识、高层管理的支持和企业内部有效的沟通系统。 | Aditya Parida Daniel Johansson Martin Edelman 梁工谦 邱若娟 | 2005 | 设备管理与维修2005，，11： | 3 |
| 4 | Development of Low Carbon Microalloyed High Strength Ultra-Thin Cast Strip Products Produced by the Castrip~ Process With Excellent Strength-Ductility Properties显示文摘The CASTRIP* process produces a range of high strength Ultra-thin Cast Strip (UCS) products (380-550 MPa) in thicknesses between 0.9 mm and 1.5 mm, which is very challenging to produce via conventional hot and cold rolled processing routes. The twin roll CASTRIP process fully exploits the hardenability and strengthening potential of Nb in a low C-Mn-Nb-V microalloyed steel type. Significant microstructural strengthening from solute Nb was obtained, even at low microalloying levels, as well as modest Mn additions, through enhancing the hardenability and further strengthening was obtained in coated products by exploiting age hardening during processing on a continuous hot dip galvanising line. Atom probe tomography and TEM determined that Nb was retained in solid solution and subsequent age hardening resulted from the formation of Nb and V rich nanosized particles. Age hardening was achieved without loss of ductility producing galvanised strip with an excellent strength-ductility combination (Y.S. >600 MPa, T.E. >10%). | C.R. Killmore K.R. Carpenter H.R. Kaul D.G. Edelman J.M. Cairney S.P. Ringer J.G. Williams P.C. Campbell W.N. Blejde | 2011 | Journal of Iron and Steel Research(International)2011，18，S1： | 3 |
| 5 | Evolved to adapt: A computational approach to animal innovation and creativity显示文摘 | Oren KOLODNY Shimon EDELMAN Arnon LOTEM | 2015 | Current Zoology2015，61，2： | 2 |
| 6 | 可溶性CD40酶联检测试剂盒的研制及其检测的临床意义显示文摘目的 :建立灵敏、特异和稳定的人可溶性CD4 0 (sCD4 0 )酶标检测试剂盒及探讨其检测的临床意义。方法 :采用该室制备的鼠抗人CD4 0单抗 5C11作为包被抗体 ,另一株识别不同抗原位点的单抗 3G3经生物素 (biotin)标记后作为检测抗体 ,建立双单抗夹心的人sCD4 0酶标检测方法和对各种质控参数进行优化。在此基础上测定了健康供血员、甲亢、慢性肾炎、白血病、类风湿性关节炎患者的血清、肺癌患者血清和胸水及多种多发性骨髓瘤 (MM)、淋巴瘤细胞株培养上清中sCD4 0的含量。结果 :成功地研制了人sCD4 0酶联检测试剂盒 ,其灵敏度为 15 6pg ml。该试剂盒 4℃放置 3个月 ,离散度 (CV) <± 7 9% ,回收率为 95 %~ 114 % ,提示检测方法具有良好的灵敏度、稳定性和准确性。用该试剂盒测得血清中sCD4 0含量的 95 %正常值范围 (x±s)为 10 5 0 0± 18 88pg ml,甲亢、慢性肾炎、白血病、类风湿患者的血清、肺癌患者血清和胸水中sCD4 0的含量明显高于正常对照组 (P <0 0 1)。结论 :成功地研制了检测人sCD4 0酶标检测试剂盒 ,对一些与CD4 0分子表达或信号异常的疾病患者外周血检测结果显示 。 | 庄羽美 黄建安 朱华亭 周璇 马泓冰 王凤鸣 Elisabeth Monchatre Léna Edelman 张学光 | 2004 | 中国免疫学杂志2004，20，8： | 2 |
| 7 | Basic fibroblast growth factor in a porcine model of chronic myocardial ischemia:a comparison of angiogenic,echocardiographic and coronary flow parameters显示文摘 | Edelman ER Stamler A | 1997 | JPET1997，282，： | 1 |
| 8 | Laparoscopic Paraesophgeal hernia repair with mesh显示文摘 | Edelman DS | 1995 | Surg Laparosc Endosc1995，5，1： | 1 |
| 9 | Treatment options for brain metastases in pati- ents with non-small cell lung cancer显示文摘 | Taimur S Edelman MJ | 2003 | Curr Treat Options Oncol2003，4，1： | 1 |
| 10 | 16 X-chromosome STR loci frequency data from a German population 显示文摘 | Edelman J Hering S Michael M | 2001 | Forensic Sci Int2001，124，23： | 1 |
| 11 | Artifacts in MR imaging,description,cause and solutions显示文摘 | Wesbey G Edelman RR Harris R | 1990 | Clin Magn Reson Imaging1990，，5： | 1 |
| 12 | Leukocyte recruitment and expression of chemokines following different forms of vascular injury显示文摘 | Welt FG Tso C Edelman ER | 2003 | Vasc Med2003，8，1： | 1 |
| 13 | Intrauterine lidocaine infusion for pain management in first-trimester abortions显示文摘 | EDELMAN A NICHOLS M D LECLAIR C | 2004 | Obstet Gynecol2004，103，6： | 1 |
| 14 | Erectile dysfunction and diabetes显示文摘 | Chu NV Edelman SV | 2002 | Curr Diab Rep2002，2，1： | 1 |
| 15 | Pathobiologic responses to stenting 显示文摘 | Edelman E R Rogers C | 1998 | Am J Cardiol1998，81，7： | 1 |
| 16 | Basic fibrob last growth factor enhances the coupling of intimal hyperplasia andproliferation of vasa vasorum in injured rat arteries 显示文摘 | EDELMAN ER NUGEN MA SMITH LT | 1992 | J Clin Invest1992，89，2： | 1 |
| 17 | EC145 : a novel targe- ted agent for adenocarcinoma of the lung 显示文摘 | PRIBBLE P EDELMAN M J | 2012 | Expert Opin Investig Drugs2012，21，5： | 1 |
| 18 | Optimal duration of chemotherapy in advanced non-small-cell lung cancer显示文摘 | Lustberg MB Edelman MJ | 2007 | Curr Treat Options Oncol2007，8，1： | 1 |
| 19 | Psychological adaptation to ICDs and the influ- ence of anxiety sensitivity 显示文摘 | Lemon J Edelman S | 2007 | Psychol Health Med2007，12，2： | 1 |
| 20 | Molecular epidemiology of A/H3N2 and A/H1N1 influenza vires during a single epidemic season in the United States 显示文摘 | Nelson MI Edelman L Spiro D J | 2008 | PLoS Pathog2008，4，10： | 1 |
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