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12篇 您的检索式:作者名="Daniel Jacobson"
    题名 作者 年代 出处 被引量
1Preservation of immune function in cervical cancer patients during chemoradiation using a novel integrative approach显示文摘Susan K. Lutgendorf Elizabeth Mullen-Houser Daniel Russell Koen DeGeest Geraldine Jacobson Laura Hart David Bender Barrie Anderson Thomas E. Buekers Michael J. Goodheart Michael H. Antoni Anil K. Sood David M. Lubaroff 2010Brain Behavior and Immunity2010,,8:2
2Letting the (Energy) Gini out of the Bottle Lorenz Curves of Cumulative Electricity Consumption and Gini Coefficients as Metrics of Energy Distribution and Equity 显示文摘Jacobson Ame Miman Anita D Kammen Daniel M 2005Energy Policy2005,33,14:1
3'Earnings Losses of Displaced Workers显示文摘Jacobson Louis S Robert J.LaLonde Daniel G.Sullivan 0,,04:1
4Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents显示文摘Ross P L Huang Y N Marchese J N Williamson B Parker K Hattan S Khainovski N Pillai S Dey S Daniels S Purkayastha S Juhasz P Martin S Bartlet-Jones M He F Jacobson A Pappin D J 0,,12:1
5Preservation of immune function in cervical cancer patients during chemoradiation using a novel integrative approach显示文摘Susan K. Lutgendorf Elizabeth Mullen-Houser Daniel Russell Koen DeGeest Geraldine Jacobson Laura Hart David Bender Barrie Anderson Thomas E. Buekers Michael J. Goodheart Michael H. Antoni Anil K. Sood David M. Lubaroff 2010Brain Behavior and Immunity2010,,8:1
6Quality of Life and Exercise Performance in Patients in Sinus Rhythm Versus Persistent Atrial Fibrillation显示文摘Steven N. Singh X. Charlene Tang Bramah N. Singh Paul Dorian Domenic J. Reda Crystal L. Harris Ross D. Fletcher Satish C. Sharma J. Edwin Atwood Alan K. Jacobson H. Daniel Lewis Becky Lopez Dennis W. Raisch Michael D. Ezekowitz 2006Journal of the American College of Cardiology2006,,4:1
7Letting the (energy) Gini out of the bottle: Lorenz curves of cumulative electricity consumption and Gini coefficients as metrics of energy distribution and equity显示文摘Arne Jacobson Anita D. Milman Daniel M. Kammen 2004Energy Policy2004,,14:1
8Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents 显示文摘Ross PL Huang YN Marchese JN Williamson B Parker K Hattan S Khainovski N Pillai S Dey S Daniels S Purkayastha S Juhasz P Martin S Bartlet-Jones M He F Jacobson A Pappin DJ 2004Mol Cell Proteomics2004,3,:1
9Risk of Unintentional Overdose with Non-Prescription Acetaminophen Products显示文摘Michael S. Wolf Jennifer King Kara Jacobson Lorenzo Francesco Stacy Cooper Bailey Rebecca Mullen Danielle McCarthy Marina Serper Terry C. Davis Ruth M. Parker 2012Journal of General Internal Medicine2012,,12:1
10以人群为基础的生物监测:纽约市有机磷和拟除虫菊酯类杀虫剂暴露显示文摘[背景]有机磷类和拟除虫菊酯类是两类美国最常见的杀虫剂。这些杀虫剂广泛用于控制纽约市建筑物里的虫害,所导致的杀虫剂暴露可能比比在欠城市化的环境中更高。[目的]估计纽约市杀虫剂暴露的参考值,并确定人口学特征和行为特征以预测暴露。[方法]2004年纽约市健康与营养调查是一项在人群基础上的横断面研究,研究对像为≥20岁的成年人。检测883名参加者的尿中有机磷代谢产物[二甲基磷酸酯(DMP)、二甲基硫代磷酸酯(DMTP)、二甲基二硫代磷酸酯、二乙基磷酸酯、二乙基硫代磷酸酯和二乙基二硫代磷酸酯]的浓度,以及1 452名参加者的尿中拟除虫菊酯类代谢产物[3-苯氧基苯甲酸(3-PBA)、反式-3-(2,2-二氯乙烯基)-2,2-二甲基环丙烷-1-羧酸(反式DCCA)、4-氟-3-苯氧基苯甲酸和顺式-3-(2,2-二溴乙烯基)-2,2-二甲基环丙烷-1-羧酸]的浓度。使用多元线性回归在不同的预测因子类别中估计总二烃基磷酸盐(ΣDAP)的最小二乘几何平均值和3-PBA浓度。[结果]二甲基有机磷代谢产物的第95百分位浓度最高(DMP和DMTP分别为87.4μg/L和74.7μg/L)。拟除虫菊酯类代谢物中测得的最高第95百分位浓度分别为3-PBA和反式-DCCA(分别为5.23μg/L和5.94μg/L)。ΣDAP浓度随着年龄增加而增加,在非西班牙裔白人或黑人中较西班牙裔/族裔高,在专业使用杀虫剂者中较高,也随水果的消费频率增加而增加;ΣDAP浓度随非绿色蔬菜消费增加而下降。在各预测因子类别中尿3-PBA浓度几何均数的绝对差值都太小而无意义。[结论]纽约市拟除虫菊酯类和有机磷二甲酯类暴露水平估值均高于美国的整体水平,因此在制定杀虫剂的使用法规时,一定要考虑城市中虫害与杀虫剂负荷。Wendy McKelvey J.Bryan Jacobson Daniel Kass Dana Boyd Barr Mark Davis Antonia M.Calafat Kenneth M.Aldous 2014环境与职业医学2014,31,4:0
11Improved gastrointestinal health for irritable bowel syndrome with metagenome-guided interventions显示文摘Irritable bowel syndrome(IBS)is the most prevalent functional gastrointestinal disorder worldwide,and the most common reason for referral to gastroenterology clinics.However,the pathophysiology is still not fully understood and consequently current management guidelines are very symptom-specific,leading to mixed results.Here we present a study of 88 individuals with IBS who had baseline sequencing of their gut microbiome(stool samples),received targeted interventions that included dietary,supplement,prebiotic/probiotic,and lifestyle recommendations for a 30-day period,and a follow-up sequencing of their gut microbiome.The study’s objectives were to demonstrate unique metagenomic signatures across the IBS phenotypes and to validate whether metagenomic-guided interventions could lead to improvement of symptom scores in individuals with IBS.Enrolled subjects also completed a baseline and post-intervention questionnaire that assessed their symptom scores.The average symptom score of an individual with IBS at baseline was 160 and at the endpoint of the study the average symptom score of the cohort was 100.9.The mixed IBS subtype showed the most significant reduction in symptom scores across the different subtypes(average decrease by 102 points,P=0.005).The metagenomics analysis reveals shifts in the microbiome post-intervention that have been cross-validated with the literature as being associated with improvement of IBS symptoms.Given the complex nature of IBS,further studies with larger sample sizes,more targeted analyses,and a broader population cohort are needed to explore these results further.Cem Meydan Ebrahim Afshinnekoo Nate Rickard Guy Daniels Laura Kunces Theresa Hardy Loukia Lili Sarah Pesce Paul Jacobson Christopher E.Mason Joel Dudley Bodi Zhang 2020Precision Clinical Medicine2020,3,2:0
12Biological and Molecular Components for Genetically Engineering Biosensors in Plants显示文摘Plants adapt to their changing environments by sensing and responding to physical,biological,and chemical stimuli.Due to their sessile lifestyles,plants experience a vast array of external stimuli and selectively perceive and respond to specific signals.By repurposing the logic circuitry and biological and molecular components used by plants in nature,genetically encoded plant-based biosensors(GEPBs)have been developed by directing signal recognition mechanisms into carefully assembled outcomes that are easily detected.GEPBs allow for in vivo monitoring of biological processes in plants to facilitate basic studies of plant growth and development.GEPBs are also useful for environmental monitoring,plant abiotic and biotic stress management,and accelerating design-build-test-learn cycles of plant bioengineering.With the advent of synthetic biology,biological and molecular components derived from alternate natural organisms(e.g.,microbes)and/or de novo parts have been used to build GEPBs.In this review,we summarize the framework for engineering different types of GEPBs.We then highlight representative validated biological components for building plant-based biosensors,along with various applications of plant-based biosensors in basic and applied plant science research.Finally,we discuss challenges and strategies for the identification and design of biological components for plant-based biosensors.Yang Liu Guoliang Yuan Md MahmudulHassan Paul E.Abraham Julie C.Mitchell Daniel Jacobson Gerald A.Tuskan Arjun Khakhar June Medford Cheng Zhao Chang-Jun Liu Carrie A.Eckert Mitchel J.Doktycz Timothy J.Tschaplinski Xiaohan Yang 2022BioDesign Research2022,,1:0
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