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| 1 | 中国客运交通的碳排放地理特征与展望显示文摘围绕全国、省市和'一带一路'三个空间层面,对1990-2012年中国客运交通的碳排放进行了估算和分析。研究表明:1在全国层面上,公路是碳排放总量最大的运输方式,其次是航空,而铁路和水运的碳排放较低且保持稳定;2在省市层面上,交通碳排放呈现出从东部向中、西部递减的趋势,并且空间分布越来越集中在东部省份;3'一带一路'的主要城市中,'丝绸之路经济带'(简称'一带')的沿线城市表现出较低的交通碳排放,而'21世纪海上丝绸之路'(简称'一路')沿线的港口城市的交通碳排放较高,而且都以公路碳排放为主。未来在满足和控制交通需求的同时,有必要发展以铁路和公共交通为主的低碳交通模式,替代目前以公路为主的交通模式。 | 李琳娜 Becky P.Y.Loo | 2016 | 地理研究2016，35，7： | 22 |
| 2 | Spatial correlations between urbanization and river water pollution in the heavily polluted area of Taihu Lake Basin, China显示文摘在泰胡·莱克盆的水污染很长时间是在中国和国外的注意的焦点,由于它在在中国的城市的开发的最前线的位置。在数据从 84 聚在一起并且处理上基于在这个重重地弄脏的区域监视节,这研究首先分析都市化的空间模式和河水的分发污染,然后使用 GeoDa bivariate 在镇区单位的规模调查在都市化和河水污染之间的空间关联的空间自相关模型。结果证明都市化在水污染上有不利影响,并且影响在发展区域的不同层次变化。城市的镇区单位有都市化和最高的污染的高水平,但是最好的水质量;郊外的单位有都市化,而是更高的污染和更坏的水质量的底层;然而,农村单位有都市化和最低污染的底层,主要由在上游的污染,而是最糟的水质量影响了。最后,当活跃地在这个区域支持开发的进程时,城市、农村的计划委员会应该逐渐地解决落后于城市的生活和城市的开发的污染控制的问题,在农村区域和郊外的区域把优先级给集中的污水处理设备和联系管道网络范围的建设。 | 赵海霞 段学军 Becky STEWART 尤本胜 蒋晓威 | 2013 | Journal of Geographical Sciences2013，23，4： | 10 |
| 3 | Industrial and Agricultural Effects on Water Environment and Its Optimization in Heavily Polluted Area in Taihu Lake Basin, China显示文摘The deteriorating water quality in the Taihu Lake Basin has attracted widespread attention for many years, and is correlated with a sharp increase in the quantity of pollutant discharge such as agricultural fertilizers and industrial wastewater. In this study, several factors were selected for evaluating and regionalizing the water environmental capacity by ArcGIS spatial analysis, including geomorphologic characteristics, water quality goals, water body accessibility, water-dilution channels, and current water quality. Then, the spatial optimization of agriculture and industry was adjusted through overlay analysis, based on the balance between industrial space and water environmental capacity. The results show that the water environmental capacity gradually decreases from the west to the east, in contrast, the pollution caused by industrial and agricultural clustering is distributes along Taihu Lake, Gehu Lake and urban districts. The analysis of the agricultural space focuses on optimizing key protected areas of the Taihu Lake Basin, and the shores of Gehu Lake, optimally adjusting the second protected areas of the Taihu Lake Basin, and generally adjusting the urban areas of Changzhou and Wuxi cities. The analysis of industrial space focuses on optimizing the downtowns of Changzhou and Wuxi cities, optimally adjusting key protected areas and second protected areas of the Taihu Lake Basin, and generally adjusting the south and southwest of Gehu Lake. Lastly, some schemes of industrial and agricultural layouts and policies for the direction of industrial and agricultural development were proposed, reflecting a correlation between industry and agriculture and the water environment. | ZHAO Haixia YOU Bensheng DUAN Xuejun Stewart BECKY JIANG Xiaowei | 2013 | Chinese Geographical Science2013，23，2： | 7 |
| 4 | High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma显示文摘Glioblastoma(GBM),the deadliest form of brain cancer,presents long-standing problems due to its localization.Chimeric antigen receptor(CAR)T cell immunotherapy has emerged as a powerful strategy to treat cancer.IL-13-receptor-α2(IL13Rα2),present in over 75%of GBMs,has been recognized as an attractive candidate for antiglioblastoma therapy.Here,we propose a novel multidisciplinary approach to target brain tumors using a combination of fluorescent,therapeutic nanoparticles and CAR T cells modified with a targeted-quadruplemutant of IL13(TQM-13)shown to have high binding affinity to IL13Rα2-expressing glioblastoma cells with low off-target toxicity.Azide-alkyne cycloaddition conjugation of nanoparticles to the surface of T cells allowed a facile,selective,and high-yielding clicking of the nanoparticles.Nanoparticles clicked onto T cells were retained for at least 8 days showing that the linkage is stable and promising a suitable time window for in vivo delivery.T cells clicked with doxorubicin-loaded nanoparticles showed a higher cytotoxic effect in vitro compared to bare T cells.In vitro and in vivo T cells expressing TQM-13 served as delivery shuttles for nanoparticles and significantly increased the number of nanoparticles reaching brain tumors compared to nanoparticles alone.This work represents a new platform to allow the delivery of therapeutic nanoparticles and T cells to solid tumors. | Gloria B.Kim Virginia Aragon-Sanabria Lauren Randolph Hali Jiang Joshua A.Reynolds Becky S.Webb Achuthamangalam Madhankumar Xiaojun Lian James R.Connor Jian Yang Cheng Dong | 2020 | Bioactive Materials2020，5，3： | 6 |
| 5 | Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies显示文摘在地岬基因的 Oncogenic 变化在人的癌症是很普通的,导致有描绘得好的选择优点,而且不太听说得好的危险的房间。我们执行了一幅大规模 loss-of-function 屏幕识别被转变 KRAS 的结肠癌房间,然而并非由缺乏这 oncogene 的衍生物要求的基因。最高得分的基因然后在 KRAS 变异、野类型的癌症房间的一块更大的面板被测试。表示 oncogenic KRAS 的癌症房间被发现高度依赖于抄写因素 GATA2 和 DNA 复制开始管理者 CDC6。与已知的目标用许多药扩大这分析,我们发现有变异的 KRAS 的癌症房间与 topoisomerase 抑制显示出选择嗜好到 proteasome 功能,以及合成致命性。联合指向引起的这些功能改善了相对野类型的房间 KRAS 变异的房间杀死。这些观察建议新奇目标和在地岬变异的癌症为最佳的效果联合存在治疗的新方法,它传统地被看作对治疗高度倔强。 | Michael Steckel Miriam Molina-Arcas Britta Weigelt Michaela Marani Patricia H Warne Hanna Kuznetsov Gavin Kelly Becky Saunders Michael Howell Julian Downward David C Hancock | 2012 | Cell Research2012，22，8： | 5 |
| 6 | Disruption of Arabidopsis CHY1 Reveals an Important Role of Metabolic Status in Plant Cold Stress Signaling显示文摘到学习寒冷发信号,我们与 CBF3 倡导者(CBF3-LUC ) 驾驶的萤火虫酶记者基因的改变的导致寒冷的抄写为 Arabidopsis 屏蔽了异种。一异种, chy1-10,显示减少 CBF3-LUC 冷正式就职光。RNA 胶化污点分析表明内长的 CBF 的那表情也在 chy1 异种被减少。chy1-10 异种植物对冻结处理比更敏感在冷环境适应以后野类型。两野类型并且 chy1 异种植物对在温暖的温度的导致黑暗的饥饿敏感,尽管 chy1 植物是稍微更敏感的。这黑暗敏感被冷温度压制在野类型然而并非在 chy1。组成的 CBF3 表示部分在寒冷救 chy1-10 植物的敏感到黑暗处理。chy1 异种积累 CBF3-LUC 冷正式就职的氢过氧化物罐头还原剂的反应的氧种类,和申请的高水平在野类型。在异种的基因有缺陷者的基于地图的克隆在 CHY1 揭示了一个胡说八道变化,它编码 CoA hydrolase 为缬氨酸分解代谢和丰满的酸氧化需要的 peroxisomal -hydroxyisobutyryl (HIBYL ) 。我们的结果在冷应力发信号为 peroxisomal 新陈代谢建议一个角色,并且种忍耐到冷应力和导致黑暗的饥饿。 | Chun-Hai Dong Bethany K. Zolman Bonnie Bartel Byeong-ha Lee Becky Stevenson Manu Agarwal Jian-Kang Zhu | 2009 | Molecular Plant2009，2，1： | 4 |
| 7 | Global sustainability: Toward definition显示文摘 | Becky J. Brown Mark E. Hanson Diana M. Liverman Robert W. Merideth | 1987 | Environmental Management1987，，6： | 3 |
| 8 | 应对45nm缺陷挑战显示文摘在半导体行业的早期,在实施缺陷检查时,会将晶圆置于光线明亮之处,查看表面上的灰尘和其它微粒,并计算散射中心的数量。上世纪90年代初,业界领先企业开始引入在线缺陷检查,以提高良率,增加盈利并加快其产品上市步伐。如今,全球最先进的晶圆代工厂使用一整套高度自动化的缺陷检查和复查系统,借助尖端的光学或电子束技术及专门算法,可以发现并区分各种微粒和图形缺陷。 | Becky Pinto 加藤昌彦 KLA-Tencor | 2008 | 集成电路应用2008，25，1： | 2 |
| 9 | Global sustainability: Toward measurement显示文摘 | Diana M. Liverman Mark E. Hanson Becky J. Brown Robert W. Merideth | 1988 | Environmental Management1988，，2： | 2 |
| 10 | Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients显示文摘 | Sharma K Robert V Beckie M | 1997 | Kidney Inter1997，51，： | 2 |
| 11 | A behavior change intervention for women in cardiac rehabilitation 显示文摘 | Beckie TM | 2006 | J Cardiovasc Nuts2006，21，2： | 1 |
| 12 | Passengers' airport choice within multiairport regions (MARs): some insights from a stated preference survey at Hong Kong International Airport显示文摘 | Becky P Loo H | 2008 | Journal of Transport Geography2008，，16： | 1 |
| 13 | Global sustainability: Toward measurement显示文摘 | Diana M. Liverman Mark E. Hanson Becky J. Brown Robert W. Merideth | 1988 | Environmental Management1988，，2： | 1 |
| 14 | New concepts in chronic ur- ticaria显示文摘 | Becky M Vonakis Sarbjit S Saini | 2008 | Current Opinion in Immunology2008，20，： | 1 |
| 15 | 'Say It Straight' Training with mothers in chemical dependency treatment显示文摘 | Paula Englander-Goldenab Elizabeth Gitchelc Craig E. Hendersond David E.Goldena Becky | | 0，，01： | 1 |
| 16 | Transgenic oilseed rape along transportation routes and port of Vancouver in western Canada 显示文摘 | Yoshimura Y Beckie HJ Matsuo K | 2006 | Environ Biosaf Res2006，5，： | 1 |
| 17 | Herbicide - resistant weed management:focus on glypho- sate显示文摘 | Beckie H J | 2011 | Pest Management Science2011，67，9： | 1 |
| 18 | Nucleation and growth kinetics of struvite in a fluidized bed reactor 显示文摘 | Bhuiyan M I Mavinica D S Beckie R D | 2008 | Journal of Crystal Growth2008，310，： | 1 |
| 19 | Assessing critical thinking in baccalaureate nursing students: A longitudinal study显示文摘 | Beckie T M Lowry L W Barnett S | 2001 | Holi Nurs Prac2001，15，3： | 1 |
| 20 | Nucleation and growth kinetics of struvite in a fluidized bed reactor 显示文摘 | Bhuiyan M I H Mavinic D S Beckie R D | 2008 | Journal of Crystal Growth2008，301，6： | 1 |
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