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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Effect of a retrograde-viewing device on adenoma detection rate during colonoscopy: the TERRACE study显示文摘 | Anke M. Leufkens Daniel C. DeMarco Amit Rastogi Paul A. Akerman Kassem Azzouzi Richard I. Rothstein Frank P. Vleggaar Alessandro Repici Giacomo Rando Patrick I. Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H. Deprez Brian P. Sau | 2011 | Gastrointestinal Endoscopy2011，，3： | 5 |
| 3 | Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial显示文摘 | David Laharie Arnaud Bourreille Julien Branche Matthieu Allez Yoram Bouhnik Jerome Filippi Frank Zerbib Guillaume Savoye Maria Nachury Jacques Moreau Jean-Charles Delchier Jacques Cosnes Elena Ricart Olivier Dewit Antonio Lopez-Sanroman Jean-Louis Dupas F | 2012 | The Lancet2012，，9857： | 2 |
| 4 | Tumour regression grading after chemoradiotherapy for locally advanced rectal cancer: A near pathologic complete response does not translate into good clinical outcome显示文摘 | Hendrik A.M. Swellengrebel Steven L. Bosch Annemieke Cats Andrew D. Vincent Luc G.H. Dewit Vic J. Verwaal Iris D. Nagtegaal Corrie A.M. Marijnen | 2014 | Radiotherapy and Oncology2014，，1： | 2 |
| 5 | Delayed gastric emptying after standard pancreaticoduodenectomy: An analysis of 200consecutive patients显示文摘 | van-Berge-Henegouwen MI van-Gulik TM DeWit LT | 1997 | J Am Coll Surg1997，185，4： | 1 |
| 6 | Photolytic debromination of decabromodiphenyl ether(BDE209)显示文摘 | Gunilla Sö derströ m Ulla Sellströ m Cynthiaa Dewit | 2004 | Environ Sci Technol2004，38，1： | 1 |
| 7 | Pathogen avimlence and plant resistance: a key role for recognition显示文摘 | DeWit P | 1997 | Trends in Plant Science1997，2，12： | 1 |
| 8 | Simulation of assimilation, respiration and transpiration of crops显示文摘 | deWit CT | 1978 | Simulation Monographs Pudoc Wageningen1978，1978，： | 1 |
| 9 | Structure, function and application of lactoperoxidase in natural antimicrobial systems显示文摘 | J N deWit | 1996 | Netherlands Milk & Dairy Journal1996，50，： | 1 |
| 10 | Modified range-Doppler processing for FMCW synthetic apertureradar显示文摘 | DeWit J J M Meta A and Hoogeboom P | 2006 | IEEE Geoscience and Remote Sensing Letters2006，3，1： | 1 |
| 11 | A Survey of Models,Analysis Tools and ComPensation Methods for the Control of Machines with Friction显示文摘 | Armstronghelouvry B Dupont P Dewit C C | 1994 | Automatica1994，30，7： | 1 |
| 12 | Effect of solution heat treatment on galvanic coupling be-tween intermetallics and matrix in AA7075-T6显示文摘 | ANDREATTA F TERRYN H DEWIT J H W | 2003 | Corrosion Science2003，45，： | 1 |
| 13 | Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer显示文摘 | Tannock IF deWit R Berry WJ | 2004 | N Engl J Med2004，351，： | 1 |
| 14 | Indentification of several pathogenesis-related proteins in tomato leaves incoluated with Cladosporium fulvum as β-1,3-glucanse and chitinase显示文摘 | Joosten M H Dewit P J | 1989 | Plant Physiol1989，89，： | 1 |
| 15 | Target volumes in radiotherapy for high-grade malig- nant glioma of the brain 显示文摘 | JANSEN E P M DEWIT L G H VAN HERK M | 2000 | Radiotherapy and Oncolo- gy2000，56，2： | 1 |
| 16 | Delayed gastric emptying after standard pancreaticoduodenectomy versus pylorus-preserving pancreaticoduodenectomy: an analysis of 200 consecutive patients显示文摘 | van Berge HM van Gulik TM Dewit LT | 1997 | J Am Coil Surg1997，185，： | 1 |
| 17 | Spatial characterization of drought events using synthetic hydrology 显示文摘 | Burn D H DeWit W J | 1996 | Canadian Journal of Civil Engineering1996，23，6： | 1 |
| 18 | A geometric model of alternating current etching of aluminum显示文摘 | Dewit H J Boots H M J | 1983 | J Appl Phys1983，，5： | 1 |
| 19 | Photosynthes is of leaf canopies显示文摘 | DEWIT C T | 1965 | Agricultural Research Report1965，，663： | 1 |
| 20 | The effect of the apolipoprotein E phenotype on plasma lipids is not influenced by environmental variability:results of a Dutch twin study显示文摘 | Evans AE Dewit E Frants RR | | 0，，： | 1 |
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