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| 1 | Endoscopic ultrasound elastography for evaluation of lymph nodes and pancreatic masses:A multicenter study显示文摘AIM:To evaluate the ability of endoscopic ultrasound(EUS) elastography to distinguish benign from malignant pancreatic masses and lymph nodes.METHODS:A multicenter study was conducted and included 222 patients who underwent EUS examination with assessment of a pancreatic mass(n=121) or lymph node(n=101).The classification as benign or malignant,based on the real time elastography pattern,was compared with the classif ication based on the B-mode EUS images and with the fi nal diagnosis obtained by EUS-guided fi ne needle aspiration(EUS-FNA) and/or by surgical pathology.An interobserver study was performed.RESULTS:The sensitivity and specificity of EUS elastography to differentiate benign from malignant pancreatic lesions are 92.3% and 80.0%,respectively,compared to 92.3% and 68.9%,respectively,for the conventional B-mode images.The sensitivity and specificity of EUS elastography to differentiate benign from malignant lymph nodes was 91.8% and 82.5%,respectively,compared to 78.6% and 50.0%,respectively,for the B-mode images.The kappa coefficient was 0.785 for the pancreatic masses and 0.657 for the lymph nodes.CONCLUSION:EUS elastography is superior compared to conventional B-mode imaging and appears to be able to distinguish benign from malignant pancreatic masses and lymph nodes with a high sensitivity,specificity and accuracy.It might be reserved as a second line examination to help characterise pancreatic masses after negative EUS-FNA and might increase the yield of EUS-FNA for lymph nodes. | Marc Giovannini Botelberge Thomas Bories Erwan Pesenti Christian Caillol Fabrice Esterni Benjamin Monges Geneviève Arcidiacono Paolo Deprez Pierre Yeung Robert Schimdt Walter Schrader Hanz Szymanski Carl Dietrich Christoph Eisendrath Pierre Van Laethem Jean-Luc Devière Jacques Vilmann Peter Saftoiu Andrian | 2009 | World Journal of Gastroenterology2009，15，13： | 48 |
| 2 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 3 | Effect of a retrograde-viewing device on adenoma detection rate during colonoscopy: the TERRACE study显示文摘 | Anke M. Leufkens Daniel C. DeMarco Amit Rastogi Paul A. Akerman Kassem Azzouzi Richard I. Rothstein Frank P. Vleggaar Alessandro Repici Giacomo Rando Patrick I. Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H. Deprez Brian P. Sau | 2011 | Gastrointestinal Endoscopy2011，，3： | 5 |
| 4 | Endoscopic ultrasound-guided drainage of the biliary system:Techniques,indications and future perspectives显示文摘Over the last decade, endoscopic ultrasound-guided biliary drainage(EUS-BD)has evolved into a widely accepted alternative to the percutaneous approach in cases of biliary obstruction with failed endoscopic retrograde cholangiopancreaticography(ERCP). The available evidence suggests that, in experienced hands, EUS-BD might even replace ERCP as the first-line procedure in specific situations such as malignant distal bile duct obstruction. The aim of this review is to summarize the available data on EUS-BD and propose an evidence-based algorithm clarifies the role of the different EUS-BD techniques in the management of benign and malignant biliary obstructive disease. | Pieter Hindryckx Helena Degroote David J Tate Pierre H Deprez | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，2： | 4 |
| 5 | How to treat intestinal obstruction due to malignant recurrence after Whipple's resection for pancreatic head cancer: description of 2 new endoscopic techniques显示文摘The prognosis of pancreatic cancer remains poor,even after initial surgical therapy. Local recurrence after Whipple's pancreatico-duodenectomy may lead to intestinal obstruction at the level of the afferent limb or the alimentary limb. Endoscopic insertion of a selfexpandable metal stent(SEMS) into the intestinal malignant stricture is the preferred method of choice for palliation. We describe two new endoscopic techniques to treat a malignant intestinal obstruction with the insertion of a SEMS into the afferent limb and the alimentary limb. A case of malignant gastric outlet obstruction after a Whipple's resection was treated by the creation of an endoscopic gastrojejunostomy by the insertion of a lumen apposing Hot Axios stent in between the stomach and the alimentary limb under fluoroscopic and endoscopic ultrasound control. Biliary obstruction and jaundice caused by a malignant stricture of the afferent limb after a Roux-en-Y Whipple's resection was treated by the insertion of a SEMS by means of the single-balloon overtube-assisted technique under fluoroscopic control. Feasibility and advantages of both techniques are discussed. | Christina Mouradides Alaa Taha Ivan Borbath Pierre H Deprez Tom G Moreels | 2017 | World Journal of Gastroenterology2017，23，33： | 3 |
| 6 | Polymeric proanthocyanidins are catabolized by human colonic microflora into low molecular-weight phenolic acids 显示文摘 | Deprez S Brezillon C Rabot S | 2000 | J Nutr2000，130，： | 3 |
| 7 | Efficacy of Endoscopic Closure of Acute Perforations of the Gastrointestinal Tract显示文摘 | Rogier P. Voermans Olivier Le Moine Daniel von Renteln Thierry Ponchon Marc Giovannini Marco Bruno Bas Weusten Stefan Seewald Guido Costamagna Pierre Deprez Paul Fockens | 2012 | Clinical Gastroenterology and Hepatology2012，，6： | 2 |
| 8 | Current practice with endoscopic submucosal dissection in Europe: position statement from a panel of experts显示文摘 | P. Deprez J. Bergman S. Meisner T. Ponchon A. Repici M. Dinis-Ribeiro J. Haringsma | 2010 | Endoscopy2010，，10： | 2 |
| 9 | On convex principles of premium calculation显示文摘 | Deprez O Gerber H U | 1985 | Insurance: Mathematics and Economics1985，，4： | 1 |
| 10 | An improved design of air suspension for seats of mobile agricultural machines显示文摘 | Hostens I Deprez K Ramon H | | 0，，1： | 1 |
| 11 | Comfort improvement of a nonlinear suspension using global optimization and in situ measurements 显示文摘 | Deprez K Moshou D Ramon H | 2005 | Journal of Sound and Vibration2005，284，： | 1 |
| 12 | Detection of cytokines in human sural nerve biopsies:an immunohistochemical and molecular study显示文摘 | Lubke U Verlaet M | 2001 | Acta Neuropathol2001，101，4： | 1 |
| 13 | The analysis of the electrical conductivity of graphite conductivity of graphite powders during compaction 显示文摘 | Deprez N McLachlan D S | 1988 | Journal of Physics D: Applied Physics1988，21，1： | 1 |
| 14 | Carbon-14 biolabelling of (+)-catechin and proanthocyanidin oligomers in willow tree cuttings显示文摘 | DEPREZ S MILA I SCALBERT A | 1999 | J Agric Food Chem1999，47，： | 1 |
| 15 | Chemotherapy-induced structuralchanges in cerebral white matter and its correlation with impairedcognitive functioning in breast cancer patients 显示文摘 | Deprez S Amant F Yigit R | 2011 | Hum Brain Mapp2011，32，48： | 1 |
| 16 | Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma 显示文摘 | Lekanne Deprez RH Riegman PH Groen NA | 1995 | Oncogene1995，10，8： | 1 |
| 17 | Comfort Improvement of a Nonlinear Suspension Using Global Optimization and in Situ Measurements显示文摘 | Deprez K Moshou D Ramon H | 2005 | Journal of Sound and Vibration2005，284，： | 1 |
| 18 | Sulfate reduction rates and some aspects of the limnology of four lakes and a fjord in the Vestfold Hills, Antarctica显示文摘 | P. D. Franzmann G. W. Skyring H. R. Burton P. P. Deprez | 1988 | Hydrobiologia1988，，1： | 1 |
| 19 | A new application for therapeutic EUS: Main pancreatic duct drainage with a “pancreatic rendezvous technique”显示文摘 | Laurent Bataille Pierre Deprez | 2002 | Gastrointestinal Endoscopy2002，，6： | 1 |
| 20 | An improved design of air suspension for seats of mobile agricultural machines 显示文摘 | Hostens K Deprez H R | 2004 | Journal of Sound and Vibration2004，276，： | 1 |
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