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| 1 | 导致成人与儿童患者30天脑室腹腔分流失败的原因分析(英文)显示文摘OBJECTIVE The aim of this study was to provide a comprehensive benchmark of 30-day ventriculoperitoneal(VP)shunt failure rates for a single institution over a 5-year study period for both adult and pediatric patients,to compare this with the results in previously published literature,and to establish factors associated with shunt failure.METHODS A retrospective database search was undertaken to identify all VP shunt operations performed in a single,regional neurosurgical unit during a 5-year period.Data were collected regarding patient age,sex,origin of hydrocephalus,and whether the shunt was a primary or secondary shunt.Operative notes were used to ascertain the type of valve inserted,which components of the shunt were adjusted/replaced(in revision cases),level of seniority of the most senior surgeon who participated in the operation,and number of surgeons involved in the operation.Where appropriate and where available,postoperative imaging was assessed for grade of shunt placement,using a recognized grading system.Univariate and multivariate models were used to establish factors associated with early(30-day)shunt failure.RESULTS Six hundred eighty-three VP shunt operations were performed,of which 321 were pediatric and 362 were adult.The median duration of postoperative follow-up for nonfailed shunts(excluding deaths)was 1263 days(range 525-2226 days).The pediatric 30-day shunt failure rates in the authors'institution were 8.8%for primary shunts and 23.4%for revisions.In adults,the 30-day shunt failure rates are 17.7%for primary shunts and 25.6%for revisions.In pediatric procedures,the number of surgeons involved in the operating theater was significantly associated with shunt failure rate.In adults,the origin of hydrocephalus was a statistically significant variable.Primary shunts lasted longer than revision shunts,irrespective of patient age.CONCLUSIONS A benchmark of 30-day failures is presented and is consistent with current national databases and previously published data by other groups.The number of surgeons involved in shunt operations and the origin of the patient's hydrocephalus should be described in future studies and should be controlled for in any prospective work.The choice of shunt valve was not a significant predictor of shunt failure.Most previous studies on shunts have concentrated on primary shunts,but the high rate of early shunt failure in revision cases(in both adults and children)is perhaps where future research efforts should be concentrated. | Anderson IA Saukila LF Robins JMW Akhunbay-Fudge CY Goodden JR Tyagi AK Phillips N Chumas PD | 2018 | 中华神经外科疾病研究杂志2018，17，3： | 3 |
| 2 | Comparison of unenhanced magnetic resonance imaging and ultrasound in detecting very small hepatocellular carcinoma显示文摘BACKGROUND In hepatocellular carcinoma(HCC),detection and treatment prior to growth beyond 2 cm are important as a larger tumor size is more frequently associated with microvascular invasion and/or satellites.In the surveillance of very small HCC nodules(≤2 cm in maximum diameter,Barcelona clinical stage 0),we demonstrated that the tumor markers alpha-fetoprotein and PIVKA-Ⅱare not so useful.Therefore,we must survey with imaging modalities.The superiority of magnetic resonance imaging(MRI)over ultrasound(US)to detect HCC was confirmed in many studies.Although enhanced MRI is now performed to accurately diagnose HCC,in conventional clinical practice for HCC surveillance in liver diseases,unenhanced MRI is widely performed throughout the world.While,MRI has made marked improvements in recent years.AIM To make a comparison of unenhanced MRI and US in detecting very small HCC that was examined in the last ten years in patients in whom MRI and US examinations were performed nearly simultaneously.METHODS In 394 patients with very small HCC nodules,those who underwent MRI and US at nearly the same time(on the same day whenever possible or at least within 14 days of one another)at the first diagnosis of HCC were selected.The detection rate of HCC with unenhanced MRI was investigated and compared with that of unenhanced US.RESULTS The sensitivity of unenhanced MRI for detecting very small HCC was 95.1%(97/102,95%confidence interval:90.9-99.3)and that of unenhanced US was 69.6%(71/102,95%confidence interval:60.7-78.5).The sensitivity of unenhanced MRI for detecting very small HCC was significantly higher than that of unenhanced US(P<0.001).Regarding the location of HCC in the liver in patients in whom detection by US was unsuccessful,S7-8 was identified in 51.7%.CONCLUSION Currently,unenhanced MRI is a very useful tool for the surveillance of very small HCC in conventional clinical follow-up practice. | Kazuo Tarao Akito Nozaki Hirokazu Komatsu Tatsuji Komatsu Masataka Taguri Katsuaki Tanaka Testuo Yoshida Hideki Koyasu Makoto Chuma Kazushi Numata Shin Maeda | 2021 | World Journal of Hepatology2021，13，6： | 3 |
| 3 | G eant 4—a simulation toolkit显示文摘 | S. Agostinelli J. Allison K. Amako J. Apostolakis H. Araujo P. Arce M. Asai D. Axen S. Banerjee G. Barrand F. Behner L. Bellagamba J. Boudreau L. Broglia A. Brunengo H. Burkhardt S. Chauvie J. Chuma R. Chytracek G. Cooperman G. Cosmo P. Degtyarenko A. Del | 2003 | and Methods in Physics Research, A2003，，3： | 3 |
| 4 | Real impact of tumor marker AFP and PIVKA-II in detecting very small hepatocellular carcinoma(≤2 cm,Barcelona stage 0)-assessment with large number of cases显示文摘BACKGROUND In hepatocellular carcinoma(HCC),detection and treatment prior to growth beyond 2 cm are relevant as a larger tumor size is more frequently associated with microvascular invasion and/or satellites.AIM To examine the impact of the tumor marker alpha-fetoprotein(AFP)or PIVKA-II in detecting very small HCC nodules(≤2 cm in maximum diameter,Barcelona stage 0)in the large number of very small HCC.The difference in the behavior of these tumor markers in HCC development was also examined.METHODS A total of 933 patients with single-nodule HCC were examined.They were subdivided into 394 patients with HCC nodules≤2 cm in maximum diameter and 539 patients whose nodules were>2 cm.The rates of patients whose AFP and PIVKA-II showed normal values were examined.RESULTS The positive ratio of the marker PIVKA-II was significantly different(P<0.0001)between patients with nodules≤2 cm in diameter and those with nodules>2 cm,but there was no significant difference in AFP(P=0.4254).In the patients whose tumor was≤2 cm,50.5%showed normal levels in AFP and 68.8%showed normal levels in PIVKA-II.In 36.4%of those patients,both AFP and PIVKA-II showed normal levels.The PIVKA-II-positive ratio was markedly increased with an increase in the tumor size.In contrast,the positivity in AFP was increased gradually and slowly.CONCLUSION In the surveillance of very small HCC nodules(≤2 cm in diameter,Barcelona clinical stage 0)the tumor markers AFP and PIVKA-II are not so useful. | Kazuo Tarao Akito Nozaki Hirokazu Komatsu Tatsuji Komatsu Masataka Taguri Katsuaki Tanaka Makoto Chuma Kazushi Numata Shin Maeda | 2020 | World Journal of Hepatology2020，12，11： | 2 |
| 5 | Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma显示文摘 | Chuma M Sakamoto M Yasuda J | 2004 | J Hepatology2004，41，： | 1 |
| 6 | Pulmonary Meningioma:a light and electron-microscopic study显示文摘 | Chumas JC Lorelle CA | 1982 | Am J Surg Pathol1982，6，8： | 1 |
| 7 | Correlations between neuropsychological test results and P300 latency during silent-count and button-press tasks in post-traumatic brain injury patients显示文摘 | Reza F Ikoma K Chuma T | 2006 | Clin Neurosci(S1065-6766)2006，13，9： | 1 |
| 8 | EBP50, a β-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma显示文摘 | Tatsuhiro Shibata Makoto Chuma Akiko Kokubu Michiie Sakamoto Setsuo Hirohashi | 2003 | Hepatology2003，，1： | 1 |
| 9 | Case report:solitary plasmacytoma of the frontal bone显示文摘 | Wilson P Chumas P Walt D | 1990 | Clin Radiol1990，43，： | 1 |
| 10 | The management of pseudomyxoma peritonei显示文摘 | Mann WJ Jr Wagner J Chumas J | | 0，，7： | 1 |
| 11 | High-grade pelvic sarcoma after radiation therapy for low-grade endometrial stromal sarcoma显示文摘 | Chumas JC Patsner B Mann WJ | 1990 | Gynecol Oncol1990，36，3： | 1 |
| 12 | Repetitive transcranial magnetic stimulation of eontralesional primary motor cortex improves hand function after stroke显示文摘 | Takeuehi N Chuma T Matsuo Y | 2005 | Stroke2005，36，12： | 1 |
| 13 | Expression of the major core antigen VP7 of African horse sickness virus by a recombinant baculovirus and its use as a group-specific diagnostic reagent显示文摘 | CHUMA T LE BLOIS H SANCHEZ-VIZCAiNO J M | 1992 | J Gen Virol1992，73，4： | 1 |
| 14 | The non-structural proteins of bluetongue virus are a dominant source of cytotoxic T cell pep- tide determinants显示文摘 | Jones L D Chuma T Hails R | 1996 | Gen Virol1996，77，： | 1 |
| 15 | Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke显示文摘 | Takeuchi N Chuma T Matsuo Y | 2005 | Stroke2005，36，： | 1 |
| 16 | Overexpression of cortac-tin is involved in motility and metastasis of hepatocellular carcino-ma 显示文摘 | Chuma M Sakamoto M Yasuda J | 2004 | J Hepatol2004，41，： | 1 |
| 17 | The influence of hepatitis B DNA level and antiviral therapy on recurrence after initial curative treatment in patients with hepatocelluiar cardnoma显示文摘 | Chuma M Hige S Kamiyama T | 2009 | J Gastroenterol2009，44，9： | 1 |
| 18 | The influence of hepatitis?B DNA level and antiviral therapy on recurrence after initial curative treatment in patients with hepatocellular carcinoma显示文摘 | Makoto Chuma Shuhei Hige Toshiya Kamiyama Takashi Meguro Atsushi Nagasaka Kazuaki Nakanishi Yoshiya Yamamoto Mitsuru Nakanishi Toshihisa Kohara Takuya Sho Keiko Yamamoto Hiromasa Horimoto Tomoe Kobayashi Hideki Yokoo Michiaki Matsushita Satoru Todo Masahi | 2009 | Journal of Gastroenterology2009，，9： | 1 |
| 19 | Expression profiling in multistage hepatocarcinogenesis: Identification of HSP70 as a molecular marker of early hepatocellular carcinoma显示文摘 | Makoto Chuma Michiie Sakamoto Ken Yamazaki Tsutomu Ohta Misao Ohki Masahiro Asaka Setsuo Hirohashi | 2003 | Hepatology2003，，1： | 1 |
| 20 | Obstructive hydrocephalus following herpes simplex virus type 1 encephalitis treated by repeated third ventriculostomy 显示文摘 | Tyagi A Chumas P Ferrie C | 2001 | Pediatr Neurosurg2001，34，5： | 1 |
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