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| 1 | Chemokines and atherosclerosis: focus on the CX3CL1/CX3CR1 pathway显示文摘动脉粥样硬化当前被认为煽动性的疾病。许多注意作为预示 / 诊断的标记或动脉粥样硬化患者的治疗学的目标集中于煽动性的调停人的潜在的角色心血管的疾病。CX3CL1 (或 fractalkine ) 有一口井的在结构上和机能上地独特的 chemokine 被记录在动脉粥样硬化的角色。在它的膜界限形式,它支持卷白细胞到容器墙上的坚挺的粘附,当在它的可溶的形式它为表示 CX3CR1 房间用作有势力 chemoattractant 时。另外, CX3CL1 在脉管的房间上在内皮细胞层以及 anti-apoptotic 和 proliferative 效果上施加细胞毒素的效果,影响动脉粥样硬化患者匾的上下文和稳定性。动物模型上的研究证明了 CX3CL1/CX3CR1 小径的封锁改善动脉粥样硬化的严厉,当基因传染病学证实了那时,一条遗传上定义的不太活跃的 CX3CL1/CX3CR1 小径在人与动脉粥样硬化患者疾病的减少的风险被联系。尽管几研究在 atherogenesis 和匾 destabilization 支持 CX3CL1/CX3CR1 的一个重要病原的角色,这未必确实建议这条小径是一个合适的治疗学的目标或 CX3CL1 能用作预示 / 诊断的 biomarker。CX3CL1/CX3CR1 chemokine 小径上的进一步的研究清楚地被保证在动脉粥样硬化认为它的角色的临床的关联正当。 | Stavros APOSTOLAKIS Demetrios SPANDIDOS | 2013 | Acta Pharmacologica Sinica2013,34,10: | 17 |
| 2 | G eant 4—a simulation toolkit显示文摘 | S. Agostinelli J. Allison K. Amako J. Apostolakis H. Araujo P. Arce M. Asai D. Axen S. Banerjee G. Barrand F. Behner L. Bellagamba J. Boudreau L. Broglia A. Brunengo H. Burkhardt S. Chauvie J. Chuma R. Chytracek G. Cooperman G. Cosmo P. Degtyarenko A. Del | 2003 | and Methods in Physics Research, A2003,,3: | 3 |
| 3 | Field reconnaissance of the 2007 Niigata-Chuetsu Oki earthquake显示文摘作为到日本的 2007 Tri中心领域使命的部分,一个侦察队从也就是,设计研究中心的三美国地震十四个研究生和三个教师成员包括了地震工程研究( MCEER )的多学科的中心,中间美洲的地震中心( MAE ),并且和平的地震设计研究中心(同伴),立即在 2007 Niigata-Chuetsu Oki 地震以后带了侦察访问去影响区域。这个使命提供了一个机会考察发生的地震损坏的性质,以及从一个教育观点估计损坏的意义。这篇论文在地震的地震学上的特征上报导, geotechnical 的初步的调查结果和结构的损坏,和观察失败或倒塌的原因。另外,经济、社会经济的考虑和经验被介绍提高地震跳回。 | Georgios Apostolakis Bing Qu Nurhan Ecemis Seda Dogruel | 2007 | Earthquake Engineering and Engineering Vibration2007,6,4: | 3 |
| 4 | Solitary fibrous tumor of the liver expressing CD34 and vimentin:A case report显示文摘A case of a successfully treated solitary fibrous tumor (SFT) of the liver is reported.An 82-year-old female presented with left upper abdominal discomfort,a firm mass on palpation,and imaging studies revealed a large tumor,15 cm in diameter,arising from the left lobe of the liver.A formal left hepatectomy was performed.Microscopic evaluation showed spindle and fibroblast-like cells within the collagenous stroma.Immunohistochemistry disclosed diffuse CD34 and positive vimentin,supporting the diagnosis of a benign SFT.The patient remained well 21 months after surgery.SFT of the liver is a very rare neoplasm of mesenchymal origin.In most cases it is a benign lesion,although some may have malignant histological features and recur locally or metastasize.With less than 30 reported cases in the literature,little can be said regarding its natural history or the benefits of adjuvant radiochemotherapy.Complete surgical resection remains the cornerstone of its treatment. | Dimitris P Korkolis Katerina Apostolaki Chrysanthi Aggeli George Plataniotis Emmanuel Gontikakis Dimitra Volanaki Maria Sebastiadou Dimitris Dimitroulopoulos Dimitris Xinopoulos George N Zografos Perikles P Vassilopoulos | 2008 | World Journal of Gastroenterology2008,14,40: | 3 |
| 5 | Erythrocyte Duffy antigen receptor for chemokines (DARC): diagnostic and therapeutic implications in atherosclerotic cardiovascular disease显示文摘动脉粥样硬化是煽动性的疾病。最后三个十年努力被作了阐明在 atherogenesis 和匾开发的过程被含有的生物化学的小径。Chemokines 是在这个过程的每步的关键调停人。另外,外部血的细胞的部件在动脉粥样硬化患者损害的形成和前进被证明调停人重要。然而,直到最近,数据主要正在集中于白血球和血小板。红血球被考虑 unreceptive 旁观者和有限数据在动脉粥样硬化患者匾的前进和 destabilization 支持了他们的重要性。通过他们为 chemokines (DARC ) 的 Duffy 抗原受体,最近,红血球作为导致 chemokine 的小径的呼吁的管理者被建议了。对每隔一 chemokine 受体 DARC 不一样从 CC 和 CXC chemokine 亚科为几 ligands 拥有高亲密关系。而且, DARC 没被联合到 G 蛋白质或任何另外的细胞内部的发信号系统;因此产生第二条消息不能。红血球 DARC 的准确生物化学的角色尚待坚定。它然而正在质问 DARC 是一个管理者的事实几乎每 CC 和 CXC chemokine ligand 并且因此, DARC 对抗能有效地堵住复杂 pre 煽动性的 chemokine 网络。在现在的评论我们提供在动脉粥样硬化通过 Duffy 抗原系统集中于 erythrocyte-chemokine 相互作用支持红血球的角色的最近的证据的目的。 | Stavros APOSTOLAKIS Georgios K CHALIKIAS Dimitrios N TZIAKAS Stavros KONSTANTINIDES | 2011 | Acta Pharmacologica Sinica2011,32,4: | 2 |
| 6 | Antegrade or retrograde cerebral perfusion as an adjunct during hypothermic circulatory arrest for aortic arch surgery显示文摘 | Apostolakis E Shuhaiber JH | 2007 | Expert Rev Cardiovasc Ther2007,5,6: | 1 |
| 7 | Sutureless technique to support anastomosis during thoracic aorta replacement 显示文摘 | Apostolakis E E Leivaditis V N Anagnostopoulos C | 2009 | J Cardiothorac Surg2009,4,: | 1 |
| 8 | Nasal Delivery of Antigen with the B Subunit of Escherichia coli Heat-Labile Enterotoxin Augments Antigen-Specific T-Cell Clonal Expansion and Differentiation 显示文摘 | Apostolaki Maria Williams Neil A | 2004 | Infection and Immunity2004,72,7: | 1 |
| 9 | Interleukin 8 and Susceptibility to Coronary Artery Disease: a Population Genetics Perspective.显示文摘 | Konstantina Vogiatzi Stavros Apostolakis Vassilios Voudris Sophia Thomopoulou Georgios E. Kochiadakis Demetrios A. Spandidos | 2008 | Journal of Clinical Immunology2008,,4: | 1 |
| 10 | Genetic diversity of RANTES gene promoter and susceptibility to coronary artery disease and restenosis after percutaneous coronary intervention显示文摘 | Konstantina Vogiatzi Vassilis Voudris Stavros Apostolakis Georgios E. Kochiadakis Sofia Thomopoulou Apostolos Zaravinos Demetrios A. Spandidos | 2009 | Thrombosis Research2009,,: | 1 |
| 11 | The convergence process in heritage tourism 显示文摘 | Apostolakis A | 2003 | Annals of Tourism Research2003,,4: | 1 |
| 12 | Clinical relevance of circulating CK-19 mRNA positive cells detected during the adju vant tamoxifen treatment in patients with early breast cancer 显示文摘 | Xenidis N Markos V Apostolaki S | 2007 | Ann Oncol2007,18,10: | 1 |
| 13 | Lung dysfunction fol- lowing cardiopulmonary bypass显示文摘 | Apostolakis E Filos KS Koletsis E etal | 2010 | J Card Surg2010,25,1: | 1 |
| 14 | Genetic diversity of the host and severe revere respiratory syncytial virus-induced lower respiratory tract infection virginia amanatidou显示文摘 | Amanatidou V Apostolakis S Spandidos DA | 2009 | Pediatr Infect Dis J2009,28,2: | 1 |
| 15 | Strategies to pre-vent intraoperative lung injury during cardiopulmonary bypass 显示文摘 | Apostolakis EE Koletsis EN Baikoussis NG | 2010 | JCardiothorac Srn^2010,,5: | 1 |
| 16 | Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits 显示文摘 | Chronidou F Apostolakis E Papapostolan I | 2009 | J Cardiothorac Surg2009,,: | 1 |
| 17 | Angiotensin II up-regulates CX3CR1 expression in THP-1 monocytes: impact on vascular in- flammation and atherogenesis 显示文摘 | Apostolakis S Vlata Z Vogiatzi K | 2010 | J Thromb Thromholysis2010,29,4: | 1 |
| 18 | Geant4 developments and application显示文摘 | Allison J Amako K Apostolakis J | 2006 | IEEE Transactions on Nuclear Science2006,53,1: | 1 |
| 19 | Epidermal growth factor activates reproductive behaviour independent of ovarian steroids in female rodents显示文摘 | Apostolakis EM Garai J Lohmann JE | 2000 | Mol Endocrinol2000,14,: | 1 |
| 20 | Isomorph expression of BAG-1 gene, ER and PR in endometrial cancer 显示文摘 | Porichi O Nikolaidou ME Apostolaki A | 2010 | Antieaneer Res2010,30,10: | 1 |