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| 1 | 导致成人与儿童患者30天脑室腹腔分流失败的原因分析(英文)显示文摘OBJECTIVE The aim of this study was to provide a comprehensive benchmark of 30-day ventriculoperitoneal(VP)shunt failure rates for a single institution over a 5-year study period for both adult and pediatric patients,to compare this with the results in previously published literature,and to establish factors associated with shunt failure.METHODS A retrospective database search was undertaken to identify all VP shunt operations performed in a single,regional neurosurgical unit during a 5-year period.Data were collected regarding patient age,sex,origin of hydrocephalus,and whether the shunt was a primary or secondary shunt.Operative notes were used to ascertain the type of valve inserted,which components of the shunt were adjusted/replaced(in revision cases),level of seniority of the most senior surgeon who participated in the operation,and number of surgeons involved in the operation.Where appropriate and where available,postoperative imaging was assessed for grade of shunt placement,using a recognized grading system.Univariate and multivariate models were used to establish factors associated with early(30-day)shunt failure.RESULTS Six hundred eighty-three VP shunt operations were performed,of which 321 were pediatric and 362 were adult.The median duration of postoperative follow-up for nonfailed shunts(excluding deaths)was 1263 days(range 525-2226 days).The pediatric 30-day shunt failure rates in the authors'institution were 8.8%for primary shunts and 23.4%for revisions.In adults,the 30-day shunt failure rates are 17.7%for primary shunts and 25.6%for revisions.In pediatric procedures,the number of surgeons involved in the operating theater was significantly associated with shunt failure rate.In adults,the origin of hydrocephalus was a statistically significant variable.Primary shunts lasted longer than revision shunts,irrespective of patient age.CONCLUSIONS A benchmark of 30-day failures is presented and is consistent with current national databases and previously published data by other groups.The number of surgeons involved in shunt operations and the origin of the patient's hydrocephalus should be described in future studies and should be controlled for in any prospective work.The choice of shunt valve was not a significant predictor of shunt failure.Most previous studies on shunts have concentrated on primary shunts,but the high rate of early shunt failure in revision cases(in both adults and children)is perhaps where future research efforts should be concentrated. | Anderson IA Saukila LF Robins JMW Akhunbay-Fudge CY Goodden JR Tyagi AK Phillips N Chumas PD | 2018 | 中华神经外科疾病研究杂志2018，17，3： | 3 |
| 2 | 含有菊粉但不含羽扇豆的饲粮有助预防实验诱导的猪痢疾显示文摘猪痢疾是一种传染性黏膜出血的腹泻疾病,由定植于肠道的猪痢疾短螺旋体引起,能够诱发盲肠和结肠发炎。据报道饲料中添加菊苣根和甜羽扇豆可预防猪痢疾。本试验旨在验证是菊苣根中的菊粉而不是羽扇豆中的半乳糖起到保护作用的假设。 | Hansen C F Phillips N D La T.(等) 闫轶洁(译) 无 | 2010 | 养猪2010，，6： | 2 |
| 3 | Language performance in Alzheimer's disease and mild cognitive impairment: A comparative review 显示文摘 | Taler V Phillips N A | 2008 | J Clin Experim Neuropsychol2008，30，5： | 1 |
| 4 | Tectonic setting of synorogenic gold deposits of the Pacific Rim显示文摘 | Goldfarb R J Phillips G N Nokleherg W J | 1998 | Ore Geology Reviews1998，13，： | 1 |
| 5 | The Montreal Cog- nitive Assessment, MoCA: a brief screening tool for mild cogni- tive impairment显示文摘 | Nasreddine Z S Phillips N A Bedirian V | 2005 | J Am Geriatr Soc2005，53，4： | 1 |
| 6 | The influence of diet and/or exercise and parental compliance on health-related quality of life in obese children显示文摘 | Yackobovitch-Gavan M Nagelberg N Phillip M | | 0，，06： | 1 |
| 7 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 8 | The Montreal Cognitive Assessment, MoCA: a brief screen- ing tool for mild cognitive impairment 显示文摘 | NASREDDINE Z S PHILLIPS N A BEDIRIAN V | 2005 | J Am Geriatr Soe2005，53，4： | 1 |
| 9 | The Montreal Cogni- tive Assessment, MoCA: a brief screening tool for mild cognitive im- pairment 显示文摘 | Nasreddine Z S Phillips N A Bedirian V | 2005 | J Am GeriatrSoc2005，53，4： | 1 |
| 10 | The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment 显示文摘 | NASREDDINE Z S PHILLIPS N A BED1RIAN V | 2005 | J Am Geriatr Soc2005，53，4： | 1 |
| 11 | The numerical prediction of planar viscoelastic contraction flows using the pom pom model and higher-order finite volume schemes显示文摘 | AGUAYO J P PHILLIPS P M PHILLIPS T N | 2007 | Journal of Computational Physics2007，220，2： | 1 |
| 12 | The role of healtheare delivery on outcome of meningococcal disease in children : Casecontrol study of fatal and non - fatal cases显示文摘 | Ninis N Phillips C Bailey L | 2005 | BMJ2005，330，25： | 1 |
| 13 | Nontuberculous mycobacterial immune reconstitution syndrome in HIV-infeeted patients: spectrum of disease and long-term follow-up显示文摘 | Phillips P Bonner S Gataric N | 2005 | Clin Infect Dis2005，41，： | 1 |
| 14 | Detection of lung cancer using weighted digital analysis of breath biomarkcrs显示文摘 | Phillips M Altorki N Austin JH | 2008 | Clin Chim Acta2008，393，2： | 1 |
| 15 | The birth of the 'Kodak Moment': Institutional entrepreneurship and the adoption of new technologies显示文摘 | Munir K A Phillips N | 2005 | Organization Studies2005，26，11： | 1 |
| 16 | Citibankers at citigroup: A study of the loss of institutional trust after a merger显示文摘 | Phillips N Maguire S | 2008 | Journal of Management Studies2008，45，： | 1 |
| 17 | The molecular structure of green fluorescent protein 显示文摘 | Yang F Moss L G Phillips G N Jr | 1996 | Nat Biotechnol1996，14，10： | 1 |
| 18 | Role of CO2 in the formation of gold deposits显示文摘 | Phillips G N Evans K A | 2004 | Nature2004，429，： | 1 |
| 19 | Induced myopia associated with increased scleral creep in chick and tree shrew eyes显示文摘 | Phillips J R Khalaj M McBrien N A | 2000 | Invest Ophthalmol Vis Sci2000，41，8： | 1 |
| 20 | Dolomitization front geometry,fluid flow patterns and the origin of massive dolomite 显示文摘 | Wilson E N Hardie L A Phillips O M | 1990 | America Journal of Science1990，290，5： | 1 |
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