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| 1 | Experimental Analysis of the Rotor Stator Interaction Within a High Pressure Centrifugal Compressor显示文摘An analysis of the experimental results obtained by laser two focus anemometry in the rotor-stator inter-row region of a high-speed high-pressure centrifugal compressor is presented with the aim of quantifying the unsteady effects of the rotor-stator interaction. Two complementary methods are used. First, the results are analyzed in terms of the time-averaging procedure developed by Adamczyk. The purely time dependent correlations of the velocity components are quantified. They show that the unsteady interaction is mainly due to the splitter wake-vane interaction. Then, it is shown that the rotor-stator interaction produces spatial harmonics which are identified as spinning modes by means of Fourier series. | Isabelle Trébinjac Christophe Vixège | 2002 | Journal of Thermal Science2002，11，1： | 4 |
| 2 | Common polymorphism in the PNPLA3 /adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease显示文摘 | Eric Trépo Thierry Gustot Delphine Degré Arnaud Lemmers Laurine Verset Pieter Demetter Romy Ouziel Eric Quertinmont Vincent Vercruysse Leila Amininejad Pierre Deltenre Olivier Le Moine Jacques Devière Denis Franchimont Christophe Moreno | 2011 | Journal of Hepatology2011，，4： | 2 |
| 3 | Safety,immunogenicity,and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates显示文摘Although antivirals are important tools to control severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,effective vaccines are essential to control the current coronavirus disease 2019(COVID-19)pandemic.Plant-derived virus-like particle(VLP)vaccine candidates have previously demonstrated immunogenicity and efficacy against influenza.Here,we report the immunogenicity and protection induced in rhesus macaques by intramuscular injections of a VLP bearing a SARS-CoV-2 spike protein(CoVLP)vaccine candidate formulated with or without Adjuvant System 03(AS03)or cytidine-phospho-guanosine(CpG)1018.Although a single dose of the unadjuvanted CoVLP vaccine candidate stimulated humoral and cell-mediated immune responses,booster immunization(at 28 days after priming)and adjuvant administration significantly improved both responses,with higher immunogenicity and protection provided by the AS03-adjuvanted CoVLP.Fifteen micrograms of CoVLP adjuvanted with AS03 induced a polyfunctional interleukin-2(IL-2)-driven response and IL-4 expression in CD4 T cells.Animals were challenged by multiple routes(i.e.,intratracheal,intranasal,and ocular)with a total viral dose of 106 plaque-forming units of SARS-CoV-2.Lower viral replication in nasal swabs and bronchoalveolar lavage fluid(BALF)as well as fewer SARS-CoV-2-infected cells and immune cell infiltrates in the lungs concomitant with reduced levels of proinflammatory cytokines and chemotactic factors in the BALF were observed in animals immunized with the CoVLP adjuvanted with AS03.No clinical,pathologic,or virologic evidence of vaccineassociated enhanced disease was observed in vaccinated animals.The CoVLP adjuvanted with AS03 was therefore selected for vaccine development and clinical trials. | Stéphane Pillet Prabhu SArunachalam Guadalupe Andreani Nadia Golden Jane Fontenot Pyone Pyone Aye Katharina Röltgen Gabrielle Lehmicke Philipe Gobeil Charlotte Dubé Sonia Trépanier Nathalie Charland Marc-AndréD’Aoust Kasi Russell-Lodrigue Christopher Monjure Robert V.Blair Scott D.Boyd Rudolf P.Bohm Jay Rappaport François Villinger Nathalie Landry Bali Pulendran Brian J.Ward | 2022 | Cellular & Molecular Immunology2022，19，2： | 2 |
| 4 | DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma显示文摘 | Leslie AD Christopher TR Jiandong Y | 2014 | Mod Pathol2014，27，9： | 1 |
| 5 | Deve-lopment of a novel controlled-release system for gastric retention显示文摘 | Arati AD Navnit HS Christopher TR | 1997 | Pharm Res1997，14，6： | 1 |
| 6 | Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease<!-- Doctopic: GMD -->显示文摘 | Eric Trépo Romy Ouziel Pierre Pradat Yukihide Momozawa Eric Quertinmont Christine Gervy Thierry Gustot Delphine Degré Vincent Vercruysse Pierre Deltenre Laurine Verset Beatrice Gulbis Denis Franchimont Jacques Devière Arnaud Lemmers Christophe Moreno | 2013 | Journal of Hepatology2013，，2： | 1 |
| 7 | N -glycan based biomarker distinguishing non-alcoholic steatohepatitis from steatosis independently of fibrosis显示文摘 | Bram Blomme Sven Francque Eric Trépo Louis Libbrecht Dieter Vanderschaeghe An Verrijken Piet Pattyn Yves Van Nieuwenhove Dirk Van De Putte Anja Geerts Isabelle Colle Joris Delanghe Christophe Moreno Luc Van Gaal Nico Callewaert Hans Van Vlierberghe | 2011 | Digestive and Liver Disease2011，，4： | 1 |
| 8 | Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease显示文摘 | Michael Fernandez Eric Trépo Delphine Degré Thierry Gustot Laurine Verset Pieter Demetter Jacques Devière Michael Adler Christophe Moreno | 2015 | European Journal of Gastroenterology & Hepatology2015，，： | 1 |
| 9 | EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib显示文摘 | Zakaria Ezzoukhry Christophe Louandre Eric Trécherel Corinne Godin Bruno Chauffert Sébastien Dupont Momar Diouf Jean‐Claude Barbare Jean‐Claude Mazière Antoine Galmiche | 2012 | Int. J. Cancer2012，，12： | 1 |
| 10 | Diagnosis of bowel and mesenteric injuries in blunt abdominal trauma: a prospective study显示文摘 | Fabrice Menegaux Christophe Trésallet Marylin Gosgnach Quang Nguyen-Thanh Olivier Langeron Bruno Riou | 2005 | American Journal of Emergency Medicine2005，，1： | 1 |
| 11 | Facilitating Water electrolysers for electricity-grid services in Europe through establishing standardized testing protocols显示文摘Electrolysers,which convert electricity into hydrogen,have the potential to offer a variety of electrical-grid services,therefore facilitating the integration of intermittent renewables into electrical grids.Among various activities that aim to unlock this hidden value,the 3-year European Union project QualyGridS launched in 2017 aims to establish standardized testing protocols for electrolysers to perform electricity-grid services.This paper shares experience and intermediate results of QualyGridS with respect to the testing protocols,test benches and testing results.The results of this work facilitate mutual understanding between the electricity industry and the hydrogen industry,support further development of the cross-sector testing standards,guide the design and selection of grid-service-oriented electrolyser applications and foster the transition towards a fossil-free-energy future based on high shares of hydrogen and other renewable solutions. | Shi You Regine Reissner Christoph Imboden Cyril Bourasseau Pablo Marcuello Daniel Greenhalgh Ben Green Laura Abadía Vanesa Gil Marius Bornstein Yi Zong Xu Chen Chresten Træholt | 2020 | Clean Energy2020，4，4： | 0 |
| 12 | 斯特拉斯堡国立大学图书馆改造——重现场所精神显示文摘斯特拉斯堡大学图书馆(BNU)的原始建筑建于德国威廉时期,其对称设计和严格的正方形布局反映了19世纪晚期的历史主义风格。20世纪50年代改建工作部分掩盖了原始设计中的这种突出特点。2006年至2014年的第三阶段改建工作是对这座建筑基本特点的回归。原始的中心区设计已经复原,而内部和外部之间的关系也已经复活。首先,中央楼梯凸显了穹顶设计,而且楼梯区域的照明经过了精心研究设计。这种阶梯设计既具有象征意义也是结构性元素,回归纪念碑式顶棚的形状设计,体现了建筑最初胜利凯旋的寓意。 | Nicolas Michelin Michel Delplace Cyril Trétout Valérie Dubois Etienne Challet-Hayard Brice Chapon Anne Pestel Jean-Jacques Chagnaud Christophe Bottineau Vincent Fillon | 2015 | 城市环境设计2015，0，8： | 0 |
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