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| 1 | Ovarian cancer standard of care: are there real alternatives?显示文摘Ovarian cancer remains a major issue for gynecological oncologists, and most patients are diagnosed when the disease is already advanced with a poor chance of survival. Debulking surgery followed by platinum-taxane chemotherapy is the current standard of care, but based on several different strategies currently under evaluation, some encouraging data have been published in the last 4 to 5 years. This review provides a state-of-the-art overview of the available alternatives to conventional treatment and the most promising new combinations. For example, neoadjuvant chemotherapy does not seem to be inferior to primary debulking. Despite its outcome improvements, intraperitoneal chemotherapy struggles for acceptance due to the heavy toxicity. Dose-dense chemotherapy, after showing an impressive efficacy in Asian populations, has not produced equal results in a European cohort, and the results of alternative platinum doublets are not superior to those of carboplatin and paclitaxel. In this setting, adherence to a maintenance therapy after first-line treatment and multiple(primarily antiangiogenic) agents appears to be effective. Although many questions, including the duration of maintenance treatment and the use of bevacizumab beyond progression, remain unanswered, new biologic agents, such as poly(ADP-ribose) polymerase(PARP) inhibitors, nintedanib, and mitogen-activated protein/extracellular signal-regulated kinase(MEK) inhibitors, have emerged as potential therapeutic options in the very near future. Based on the multiplicity of available strategies, the histological and molecular features of the tumor, in addition to patient's clinical condition and disease state, continue to gain importance in guiding treatment choices. | Chiara Della Pepa Giuseppe Tonini Carmela Pisano Marilena Di Napoli Sabrina Chiara Cecere Rosa Tambaro Gaetano Facchini Sando Pignata | 2015 | Chinese Journal of Cancer2015，34，1： | 5 |
| 2 | Electromechanical actuation technology for the all-electric aircraft显示文摘 | Rubertus D P Hunter L D Cecere G J | 1984 | IEEE Trans on Aerospace and Electronic Systems1984，20，3： | 1 |
| 3 | Self-rewetting heat transfer fluids and nanobrines for space heat pipes显示文摘 | Savino R di Paola R Cecere A | 2010 | Acta Astronaut2010，67，： | 1 |
| 4 | DLS measurements on nano particles produced In laminar premixed flames显示文摘 | Cecere D Bruno A | 2003 | Synthetic M etals2003，139，： | 1 |
| 5 | Dose–response relationships within the parotid gland after radiotherapy for head and neck cancer显示文摘 | Barbara Bussels Annelies Maes Patrick Flamen Philippe Lambin Katrien Erven Robert Hermans Sandra Nuyts Caroline Weltens Silvia Cecere Emmanuel Lesaffre Walter Van den Bogaert | 2004 | Radiotherapy and Oncology2004，，： | 1 |
| 6 | Rubber Toughened PBT: Influence of Processing on Morphology and Impact Properties显示文摘 | Cecer A Greco R Ragosta G | 1990 | Polymer1990，31，： | 1 |
| 7 | Predicting the outcome of chemotherapy for lung cancer显示文摘 | Rosell R Cecere F Santarpia M | 2006 | Curr Opin Pharmacol2006，6，： | 1 |
| 8 | Concomitant boost radiotherapy and multidrug chemotherapy in the neoadjuvant treatment of locally advanced rectal cancer: Results of a phase II study显示文摘 | Luciana Caravatta Gilbert D. A. Padula Vincenzo Picardi Gabriella Macchia Francesco Deodato Mariangela Massaccesi Luigi Sofo Fabio Pacelli Fabio Rotondi Giuseppe Cecere Giuseppina Sallustio Liberato Di Lullo Adele Piscopo Samantha Mignogna Pierluigi Bonom | 2011 | Acta Oncologica2011，，8： | 1 |
| 9 | Medical treatment of ad- vanced non-small cell lung cancer in elderly patients: a review of the role of chemotherapy and targeted agents显示文摘 | Meoni G Cecere FL Lucherini E | 2013 | J Geriatr Oncol2013，4，3： | 1 |
| 10 | Placental mesenchymalstem cells : a unique source for cellular cardiomyoplasty显示文摘 | Makhoul G Chiu RC Cecere R | 2013 | Ann Thorac Surg2013，95，： | 1 |
| 11 | Long-term-survival after hospitalization for community-acquired and healthcare-associated pneumonia显示文摘 | Cecere LM Rubenfeld GD Park DR | 2010 | Respiration2010，79，2： | 1 |
| 12 | Medical treatment of advanced non-small cell lung cancer in elderly patients : A review of the role of chemotherapy and targeted agents 显示文摘 | Meoni G Cecere FL Lucherini E | 2013 | J Geriatr Oncol2013，4，3： | 1 |
| 13 | Clostridium Difficile Colitis: Increasing Incidence, Risk Factors, and Outcomes in Solid Organ Transplant Recipients显示文摘 | Marylise Boutros Maha Al-Shaibi Gabriel Chan Marcelo Cantarovich Elham Rahme Steven Paraskevas Marc Deschenes Peter Ghali Philip Wong Myriam Fernandez Nadia Giannetti Renzo Cecere Mazen Hassanain Prosanto Chaudhury Peter Metrakos Jean Tchervenkov Jeffrey | 2012 | Transplantation Journal2012，，10： | 1 |
| 14 | Ablation tests on HfC-and TaC-based ceramics for aero propulsive applications显示文摘 | PIENTI L SCITI D SILVESTRON! L CECERE A SAVINO R | 2015 | Journal of the European Ceramic Society2015，35，5： | 1 |
| 15 | Adjuvant chemotherapy for non-small cell lung cancer显示文摘 | Bria E CuPPone F Cecere FL | 2007 | J Thorae Oneol2007，，： | 1 |
| 16 | Predicting the outcome of chemotherapy for lung cancer显示文摘 | RoseU R Cecere F Santarpia M | 2006 | Curr Opin Phamacol2006，6，4： | 1 |
| 17 | Usefulness of predictive tests for cancer treatment 显示文摘 | Rosell R Cuello M Cecere F | 2006 | Bull Cancer2006，93，8： | 1 |
| 18 | Current strategies to minimize toxicity of oxaliplatin: selection of pharmacogenomic panel tests显示文摘 | Raffaele Di Francia Raffaella Stefania Siesto Daniela Valente Andrea Del Buono Sergio Pugliese Sabrina Cecere Carla Cavaliere Guglielmo Nasti Gaetano Facchini Massimiliano Berretta | 2013 | Anti-Cancer Drugs2013，，10： | 1 |
| 19 | Substrate and steric specificity of hydropyrimidine hydrase显示文摘 | Galli G Morisi F | 1975 | FEBS Lett1975，57，2： | 1 |
| 20 | Predicting the outcome of chemotherapy for lung cancer 显示文摘 | Rosell R Cecere F Santarpia M | 2006 | Curr Opin Pharmacol2006，6，4： | 1 |
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