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| 1 | Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation:Effects on virus replication and recurrent hepatitis显示文摘瞄准:决定 calcineurin 禁止者, cyclosporine 和 tacrolimus 的效果,在丙肝上,在病人的周期性的丙肝的病毒(HCV ) 复制和活动张贴肝移植。方法:在我们的中心为在 1999 和 2003 之间的联系 HCV 的肝肝硬化收到了肝移植的 107 个病人的一个队的数据回顾地被分析。浆液 HCV-RNA 的水平和周期性的肝炎的活动在作为主要抑制免疫力的代理人和没在移植以后在开始的 12 瞬间以内导致胆汁的复杂并发症的不那样类似的抑制免疫力的政体收到了 cyclosporine 或 tacrolimus 的 47 个病人之间被比较。结果:HCV-RNA 在移植以后在 3 瞬间以内增加了,但是 cyclosporine 组和 tacrolimus 组之间的差别是不足道的(在 12 瞬间的 P=0.49 ) 。另外,由浆液 transaminases 决定了的周期性的肝炎并且门发炎和纤维变性的组织学的分级没在 12 瞬间(P=0.34 ) 以后显示出有效差量。结论:一个主要抑制免疫力的代理人不在肝移植以后在感染 HCV 的病人影响周期性的肝炎的正式就职或严厉的 Cyclosporine 或 tacrolimus。 | Philip Hilgard Alisan Kahraman Nils Lehmann Cornelia Seltmann Susanne Beckebaum R Stefan Ross Hideo A Baba Massimo Malago Christoph E Broelsch Guido Gerken | 2006 | World Journal of Gastroenterology2006，12，5： | 235 |
| 2 | Diagnosis of biliary strictures after liver transplantation:Which is the best tool?显示文摘AIM: To evaluate the diagnostic value of different indirect methods like biochemical parameters, ultrasound (US) analysis, CT-scan and MRI/MRCP in comparison with endoscopic retrograde cholangiography (ERC), for diagnosis of biliary complications after liver transplantation. METHODS: In 75 patients after liver transplantation, who received ERC due to suspected biliary complications, the result of the cholangiography was compared to the results of indirect imaging methods performed prior to ERC. The cholangiography showed no biliary stenosis (NoST) in 25 patients, AST in 27 and ITBL in 23 patients. RESULTS: Biliary congestion as a result of AST was detected with a sensitivity of 68.4% in US analysis (specificity 91%), of 71% in MRI (specificity 25%) and of 40% in CT (specificity 57.1%). In ITBL, biliary congestion was detected with a sensitivity of 58.8% in the US, 88.9%in MRI and of 83.3% in CT. However, as anastomotic or ischemic stenoses were the underlying cause of biliary congestion, the sensitivity of detection was very low. InMRI detected the dominant stenosis at a correct localization in 22% and CT in 10%, while US failed completely. The biochemical parameters, showed no significant difference in bilirubin (median 5.7; 4,1; 2.5 mg/dL), alkaline phosphatase (median 360; 339; 527 U/L) or gamma glutamyl transferase (median 277; 220; 239 U/L) levels between NoST, AST and ITBL.CONCLUSION: Our data confirm that indirect imaging methods to date cannot replace direct cholangiography for diagnosis of post transplant biliary stenoses. However MRI may have the potential to complement or precede imaging by cholangiography. Optimized MRCP-processing might further improve the diagnostic impact of this method. | Thomas Zoepf Evelyn J. Maldonado-Lopez Philip Hilgard Alexander Dech■ne Massimo Malago Christoph E. Broelsch Joerg Schlaak Guido Gerken | 2005 | World Journal of Gastroenterology2005，11，19： | 32 |
| 3 | Cyclosporine A, FK-506, 40-0-[2-hydroxyethyl]rapamycin and mycophenolate mofetil inhibit proliferation of human intrahepatic biliary epithelial cells in vitro显示文摘瞄准:调查 cyclosporine 的效果 A (CsA )(MMF ) , FK-506,和 mycophenolate mofetil 和 40-0-[2-hydroxyethyl ] 人的肝内的增长上的 rapamycin (RAD ) 胆汁的上皮细胞(BEC ) 在试管内。方法:BEC 与免疫从六个人的肝织物标本被孤立磁性的分离方法并且与 CsA, FK-506, RAD,和 MMF 在试管内的不同集中对待。房间的增长被 MTT 试金分别地在 24 和 48 h 术后疗法测量。变化的单程的分析被用来分析结果。在 BEC 的 CK 19 的表示被流动血细胞计数和西方的污点监视。结果:BEC 的六根线被建立。他们为 4-18 wk 在试管内幸存。流动血细胞计数分析证明这些房间总是表示了 CK19。CsA, FK-506, RAD,和 MMF 以一种剂量依赖者方式禁止了 BEC 的增长。禁止 BEC (P<0.05 ) 的增长的 CsA, FK-506, RAD,和 MMF 的最低集中分别地是 500, 100, 0.25,和 100 mug/L。然而,由 BEC 的 CK19 的表示没被改变。结论:CsA, FK-506, RAD,和 MMF 在人的肝内 BEC 在试管内上有 antiproliferative 效果,当 RAD 有最强壮的生长禁止的效果时。他们在 transplant 病人的肝新生和胆汁管损害上的可能的效果应该进一步被调查。 | Chao Liu Thomas Schreiter Andrea Frilling Uta Dahmen Christoph E Broelsch Guido Gerken Ulrich Treichel | 2005 | World Journal of Gastroenterology2005，11，48： | 7 |
| 4 | Computer-Assisted Surgery Planning for Complex Liver Resections: When Is It Helpful? A Single-Center Experience Over an 8-Year Period显示文摘 | Arnold Radtke Georgios C. Sotiropoulos Ernesto P. Molmenti Tobias Schroeder Heinz O. Peitgen Andrea Frilling Dieter C. Broering Christoph E. Broelsch Massimo Malagó | 2010 | Annals of Surgery2010，，5： | 4 |
| 5 | Right Living Donor Liver Transplantation: An Option for Adult Patients: Single Institution Experience With 74 Patients显示文摘 | Massimo Malagó Giuliano Testa Andrea Frilling Silvio Nadalin Camino Valentin-Gamazo Andreas Paul Hauke Lang Ulrich Treichel Vito Cicinnati Guido Gerken Christoph Erich Broelsch | 2003 | Annals of Surgery2003，，6： | 2 |
| 6 | General Handling and Anesthesia for Experimental Surgery in Pigs显示文摘 | Gernot M. Kaiser Matthias M. Heuer Nils R. Frühauf Christian A. Kühne Christoph E. Broelsch | 2006 | Journal of Surgical Research2006，，1： | 2 |
| 7 | Complications of Biliary Tract in Liver Transplantation显示文摘 | Giuliano Testa Massimo Malagò Christoph E. Broelsch | 2001 | World Journal of Surgery2001，，10： | 2 |
| 8 | Bleeding problems in patients undergoing segmental liver transplantation显示文摘 | Testa G Malago M Broelsch CE | 2000 | Blood Coagul Fibrinolysis2000，11，1： | 1 |
| 9 | Application of reduced size liver transplants as split grafts, auxiliary orthotopic grafts, and living related segmental transplants显示文摘 | Broelsch CE Emond JC Whitington PF | 1990 | Ann Surg1990，212，3： | 1 |
| 10 | A limited set of human microRNA is deregulated in follicular thyroid carcinoma 显示文摘 | WEBER F TERESI R E BROELSCH C E | 2006 | J Clin Endocrinol Metab2006，91，9： | 1 |
| 11 | Living related liver transplantation: medical and social aspects of a controversial therapy 显示文摘 | Broelsch CE Testa G Alexandrou A | 2002 | Gut2002，50，2： | 1 |
| 12 | Multidetector computed tomographic cholangiography in the evaluation of potential living liver donors显示文摘 | Tobias Schroeder Massimo Malago J?rg F. Debatin Giuliano Testa Silvio Nadalin Christoph E. Broelsch Stefan G. Ruehm | 2002 | Transplantation2002，，12： | 1 |
| 13 | From living related to in-situ split liver transplantation: how to reduce waiting-list mortality 显示文摘 | Testa G Malag6 M Broelsch CE | 2001 | PediatrTransplant2001，5，1： | 1 |
| 14 | Living donor liver transplantation in adults显示文摘 | BROELSCH CE FRILLING A TESTA G | 2003 | Eur Gastroenterol Hepatol2003，15，： | 1 |
| 15 | Major bile duct injuries after laparoscopic cholecystectomy: A tertiary center experience显示文摘 | Andrea Frilling M.D. Ph.D. Jun Li M.D. Frank Weber M.D. Nils Roman Frühauf M.D. Jennifer Engel Susanne Beckebaum M.D. Andreas Paul M.D. Thomas Z?pf M.D. Massimo Malago M.D. Ph.D. Christoph Erich Broelsch M.D. Ph.D | 2004 | Journal of Gastrointestinal Surgery2004，，6： | 1 |
| 16 | Endoscopic Therapy of Posttransplant Biliary Stenoses After Right-Sided Adult Living Donor Liver Transplantation显示文摘 | Thomas Zoepf Evelyn J. Maldonado–lopez Philip Hilgard Joerg Schlaak Massimo Malago Christoph E. Broelsch Ulrich Treichel Guido Gerken | 2005 | Clinical Gastroenterology and Hepatology2005，，11： | 1 |
| 17 | Computer-assis- ted operative planning in adult living donor liver transplanta- tion: A new way to resolve the dilemma of the middle hepat- ic vein 显示文摘 | Radtke A Nadalin S Sotiropoulos GC Molmenti EP Schroeder T Valentin-Gamazo C Lang H Bockhorn M Peitgen HO Broelsch CE Malag6 M | 2007 | World Journal of Surgery2007，31，1： | 1 |
| 18 | A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma显示文摘 | Weber F Teresi RE Broelsch CE | 2006 | J Clin Endocrinol Metab2006，91，9： | 1 |
| 19 | A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma显示文摘 | Weber F Teresi RE Broelsch CE | | 0，，： | 1 |
| 20 | In Situ Splitting of Cadaveric Livers: The Ultimate Expansion of a Limited Donor Pool显示文摘 | Xavier Rogiers Massimo Malagó Karim Gawad Karl W. Jauch Michael Olausson Wolfram T. Knoefel Matthias Gundlach Atef Bassas Lutz Fischer Martina Sterneck Martin Burdelski Christoph E. Broelsch | 1996 | Annals of Surgery1996，，3： | 1 |
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