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| 1 | 血管内超声去肾交感神经术治疗高血压:一项多中心,国际,单盲,随机,假手术对照试验显示文摘早期研究表明,基于射频的去肾交感神经术可降低中度高血压患者的血压。研究者研究了在没有使用抗高血压药物的情况下,使用血管内超声去。肾交感神经术是否会降低高血压患者的动态血压。 | 刘青 叶鹏 Azizi M Schmieder RE Mahfoud F Weber MA Daemen J Davies J Basile J Kirtane AJ Wang Y Lobo MD Saxena M Feyz L Rader F Lurz P Sayer J Sapoval M Levy T Sanghvi K Abraham J Sharp ASP Fisher NDL Bloch MJ Reeve-Stoffer H Coleman L Mullin C Mauri L | 2018 | 中华高血压杂志2018，26，10： | 27 |
| 2 | 高危患者目标血压与心血管病预后显示文摘指南推荐血压目标值应〈140/90 mmHg(1mmHg=0.133kPa)以减少心血管事件的发生。但与其他心血管病预后(如冠状动脉事件)相比,包括脑卒中及心力衰竭在内的心血管病预后与收缩压下降关系更密切。一些心血管事件(如冠状动脉事件)风险在收缩压低时亦增高,风险-收缩压关系呈J形曲线,而脑卒中与血压不是J形曲线关系。 | B?hm M Schumacher H Teo KK Lonn EM Mahfoud F Mann JF Mancia G Redon J Schmieder RE Sliwa K Weber MA Williams BYusuf S 曲浥晨 叶鹏 | 2017 | 中华高血压杂志2017，25，6： | 14 |
| 3 | 热应激和低营养摄入对猪肠道完整性和功能的影响显示文摘热应激会损害肠道完整性,并诱发肠渗漏。因此,本试验研究了直接或间接热应激(通过减少采食量)对生长猪肠道通透性的影响。选用体重(43±4)kg的杂交后备母猪(n=48),分别安置在以下控制环境中:热中性(TN)环境(20℃,湿度35%~50%,自由采食)、热应激(HS)环境(35℃,湿度20%~35%,自由采食)、热中性环境配对饲喂(PFTN,以消除不同采食量的交互影响)。第1、3、7天使猪只安乐死,采集的空肠样品被安装到尤式灌流室,测定跨膜电阻抗值(TER)和异硫氰基荧光标记的脂多糖(LPS)渗透性(APP,表示为表观渗透系数)。此外,评估肠道完整性以及应激基因和蛋白标志物。结果表明,不考虑热应激天数,HS组与TN组猪相比,血浆内毒素水平增加45%(P〈0.05),空肠TER降低30%(P〈0.05),LPS渗透率增加2倍(P〈0.01)。此外,与PFTN组相比,HS组第7天的猪LPS渗透性有增加的趋势(P=0.06)。整个试验阶段HS组溶菌酶和碱性磷酸酶活性下降,分别下降46%和59%(P〈0.05);然而,3 d和7 d空肠免疫细胞标记物——髓过氧化物酶活性增加(P〈0.05)。由此可见,热应激和减少采食量都会降低肠道完整性,并增加内毒素渗透性。推测这可能会导致炎症加重,在炎热的夏季可能是导致猪生长性能降低的原因。 | Pearce S C Mani V Weber T E Rhoads R P Patience J F Baumgard L H Gabler N K | 2016 | 中国饲料2016，，3： | 3 |
| 4 | Should antibiotics be administered before arthroscopic knee surgery? A systematic review of the literature显示文摘AIM To explore the current evidence surrounding the administration of prophylactic antibiotics for arthroscopic knee surgery. METHODS Databases were searched from inception through May of 2018 for studies examining prophylactic antibiotic use and efficacy in knee arthroscopy. Studies with patient data were further assessed for types of arthroscopic procedures performed,number of patients in the study,use of antibiotics,and outcomes with the intention of performing a pooled analysis. Data pertaining to 'deep tissue infection' or 'septic arthritis' were included in our analysis. Reported data on superficial infection were not included in our data analysis. For the pooled analysis,a relative risk ratio was calculated and χ~2 tests were used to assess for statistical significance between rates of infection amongst the various patient groups. Post hoc power analyses were performed to compute the statistical power obtained from our sample sizes. Number needed to treat analyses were performed for statistically significant differences by dividing 1 by the difference between the infection rates of the antibiotic and no antibiotic groups. An alpha value of 0.05 was used for our analysis. Study heterogeneity was assessed by Cochrane's Q test as well as calculation of the I^2 value.RESULTS A total of 49682 patients who underwent knee ar-throscopy for a diverse set of procedures across 19 studies met inclusion critera for pooled analysis. For those not undergoing graft procedures,there were 27 cases of post-operative septic arthritis in 34487 patients(0.08%) who received prophylactic antibiotics and 16 cases in 10911(0.15%) who received none [risk ratio(RR) = 0.53,95% confidence interval(CI): 0.29-0.99,P = 0.05]. A sub-group analysis in which bony procedures were excluded was performed which found no significant difference in infection rates between patients that received prophylactic antibiotics and patients that did not(P > 0.05). All anterior cruciate ligament reconstruction studies used prophylactic antibiotics,but two studies investigating the effect of soaking the graft in vancomycin in addition to standard intravenous(IV) prophylaxis were combined for analysis. There were 19 cases in 1095 patients(1.74%) who received IV antibioitics alone and no infections in 2034 patients who received IV antibiotics and had a vancomycin soaked graft(RR = 0.01,95%CI: 0.001-0.229,P < 0.01).CONCLUSION Prophylactic antibiotics are effective in preventing septic arthritis following simple knee arthroscopy. In procedures involving graft implantation,graft soaking reduces the rate of infection. | John Carney Nathanael Heckmann Erik N Mayer Ram K Alluri Carleton Thomas Vangsness George F Hatch Ⅲ Alexander E Weber | 2018 | World Journal of Orthopedics2018，9，11： | 2 |
| 5 | Which Time-to-Peak Threshold Best Identifies Penumbral Flow?: A Comparison of Perfusion-Weighted Magnetic Resonance Imaging and Positron Emission Tomography in Acute Ischemic Stroke显示文摘 | J Sobesky O Zaro Weber F -G. Lehnhardt V Hesselmann A Thiel C Dohmen A Jacobs M Neveling W -D. Heiss | 2004 | Stroke2004，，12： | 2 |
| 6 | Measurement of excited-state-absorption loss for Ce^3+ in Y3Al5O12 and implications for tunable 5d→4f rare earth laser显示文摘 | Jacobs R R Krupke W F Weber M | 1978 | J Appl Phys Lett(S0003-6951)1978，，33： | 1 |
| 7 | Ultrasonography in the initial evaluation and follow-up of blunt abdominal injury显示文摘 | Ofner D Weber F | 1993 | Surgery1993，114，3： | 1 |
| 8 | Interface formation in infiltrated AI (Si)/diamond composites 显示文摘 | BEFFORT O KHALID F A WEBER L | 2006 | Diamond and Related Materials2006，15，9： | 1 |
| 9 | Evaluation of the alaris auditory evoked potential index as an indicator of anes- thetic depth in preschool children during induction of anesthesia with sevoflurane and remifentanil 显示文摘 | WEBER F BEIN T HOBBHAHN J | 2004 | Anesthesiology2004，101，2： | 1 |
| 10 | Enhancement of transport critical current densities in (Bi,Pb)2Sr2Ca2Cu3O10/Ag tapes at 77K following fast neutron irradiation显示文摘 | HC Q Y WEBER H W SAUERZOPF F M | 1994 | Appl Phys Lett1994，65，4： | 1 |
| 11 | Immunization of broiler chicks by in ovo injection of infective stages of Eimeria显示文摘 | Weber F H Genteman K C LeMay M A | 2004 | Pouh Sci2004，83，： | 1 |
| 12 | Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein production显示文摘 | WEBER J HOFFMANN F RINAS U | 2002 | Biotechnol Bioeng2002，80，3： | 1 |
| 13 | MxA GTPase blocks reporter gene expression of reconstituted Thogoto virus ribonucleoprotein complexes 显示文摘 | Weber F Hailer O Kochs G | 2000 | J Virol2000，74，1： | 1 |
| 14 | Measurement of excited-state-absorption loss for Ce3+ in Y3Al5O12 and implications for tunable 5d→4f rare-earth lasers显示文摘 | Jacobs R R Krupke W F Weber M | | 0，，： | 1 |
| 15 | Mapping of quantitative trait loci determining agronomic important characters in hexaploid wheat (Triticum aestivum L.)显示文摘 | A. B?rner E. Schumann A. Fürste H. C?ster B. Leithold M. R?der W. Weber | 2002 | Theoretical and Applied Genetics (-)2002，，6： | 1 |
| 16 | Bonding properties of metals anodically bonded to glass 显示文摘 | Briand D Weber P Derooij N F | 2004 | Sensors and Actuators A:Physieal2004，114，23： | 1 |
| 17 | Bevacizumab combined with chemotherapy for platinum- resistant recurrent ovarian cancer: The AURELIA open-label randomized phase Ill trial 显示文摘 | PUJADE-LAURAINE E HILPERT F WEBER B | 2014 | J Clin Oneol2014，32，13： | 1 |
| 18 | RIG-I-like receptors and negative-strand RNA viruses 显示文摘 | Weber F | 2015 | Cytokine2015，76，： | 1 |
| 19 | Peroneal tendon lesions caused by antiglide plates used for fixation of lateral malleolar fractures : the effect of plate and screw position 显示文摘 | Weber M Krause F | 2005 | Foot Ankle Int2005，26，4： | 1 |
| 20 | The opera- tive treatment of scapular fracture 显示文摘 | Hardegger F H Simpson L A Weber B G | 1984 | J Bone joint Surg Br1984，66，： | 1 |
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