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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 3 | 青少年甘油磷酸胆碱代谢和心血管病的危险因素:一项队列研究显示文摘甘油磷酸胆碱(glycerophosphocholine,GPC)代谢物可调节动脉粥样硬化,从而导致心血管病风险。临床前期心血管病可能从青春期就开始。研究人员应用靶向血清脂质组学鉴定一组新的GPC,并测试在青春期时这些GPC中的任何一种是否与心血管病传统危险因子,如过量内脏脂肪、升高的血压、胰岛素抵抗和致动脉粥样硬化血脂异常相关。 | Syme C Czajkowski S Shin J Abrahamowicz M Leonard G Perron M Richer L Veillette S Gaudet D Strug L Wang Y Xu H Taylor G Paus T Bennett S Pausova Z 刘莉 叶鹏 | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 4 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 5 | Invasive Pneumococcal Disease in Children 5 Years After Conjugate Vaccine Introduction - Eight States, 1998-2005显示文摘 | Reingold A Hadler J Farley M M Harrison L Lynfield R Lexau C Bennett N Thomas A Craig A S Smith P J Beall B Whitney C G Moore M Pilishvili T | 2008 | MMWR Morbidity and Mortality Weekly Report2008，，6： | 1 |
| 6 | Reflectance-based determination of optical properties in highly attenuating tissue显示文摘 | PFEFER T J MATCHETTE L S BENNETT C L | 2003 | Journal of Biomedical Optics2003，8，2： | 1 |
| 7 | Optic neuropathy associated with laser in situ keratomileusis显示文摘 | Lee AG Kohnen T Ebner R Bennett J Miller NR Carlow TJ | 2000 | J Cataract Refract Surg2000，26，： | 1 |
| 8 | Initial ethanol expos-ure results in decreased heart rate variability in ethanol-naive r-hesus monkeys显示文摘 | Bennett A J Sponberg AC Graham T | 2001 | EurJ Pharmacol2001，433，2： | 1 |
| 9 | Feedforward-an alternative approach to amplifier linearization显示文摘 | Bennett T J Clements R F | 1974 | Radio and Elect Engineer1974，44，5： | 1 |
| 10 | Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy显示文摘 | Bennett J Tanabe T Sun D Zeng Y Kieldbye H Gouras P | 1996 | Nat Med1996，2，6： | 1 |
| 11 | A transient finite element analysis of thermoelastic effect during inertia friction welding显示文摘 | Bennett C J Hyde T H Shipway P H | | 0，，09： | 1 |
| 12 | Proposals for the classi fication of the acute leukaemias显示文摘 | J M Bennett D Catovsky M T Daniel | 1976 | British Journal of Haematology1976，33，4： | 1 |
| 13 | Greener Pastures andthe Impact of Dynamic Institutional Preferences显示文摘 | Bennett J A Sips R W Starks L T | 2003 | TheReview of Financial Studies2003，16，4： | 1 |
| 14 | EpichloO endophytes grow by intercalary hyphal extension in elongating grass leaves显示文摘 | Christensen M J Bennett R J Ansari H A Koga H Johnson R D Bryan G T Simpson W R Koolaard J P Nickless E M Voisey C R | 2008 | Fungal Genetics and Biology2008，45，2： | 1 |
| 15 | Temperature and solar radiation effects on potential maize yields across locations显示文摘 | Muchow R C Sinclair T R Bennett J M | 1990 | Agronomy Journal1990，82，： | 1 |
| 16 | Mortality in broiler chickson feed amended with Fusarium proliferatum culture material orwith purified fumonisin B1 and moniliformin显示文摘 | Javed T Bennett G A Richard J L | 1993 | Mycopathologia1993，123，： | 1 |
| 17 | An empirical test of forgiveness motives' effects on employees' health and well- being 显示文摘 | Cox S S Bennett R J Tripp T M Aquino K | 2012 | Journal of Occupational Health Psychology2012，17，3： | 1 |
| 18 | A theory of analytrical hierarchies applied to political candidacy 显示文摘 | Satty T L Bennett J P | 1997 | Behavioral Science1997，22，4： | 1 |
| 19 | Auxin transport promotes Arabidopsis lateral root initiation显示文摘 | Casimiro I Marchant A Bhalerao R P Beeckman T Dhooge S Swarup R Graham N Inzé D Sandberg G Casero P J Bennett M | 2001 | Plant Cell2001，13，4： | 1 |
| 20 | Burkitt lymphoma arising in organ transplant recipients : a clinicopathologic study of five cases显示文摘 | Gong J Z Stenzel T T Bennett E R | 2003 | Am J Surg Pathol2003，27，： | 1 |
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