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| 1 | Double-stranded DNA in exosomes: a novel biomarker in cancer detection显示文摘 | Basant Kumar Thakur Haiying Zhang Annette Becker Irina Matei Yujie Huang Bruno Costa-Silva Yan Zheng Ayuko Hoshino Helene Brazier Jenny Xiang Caitlin Williams Ruth Rodriguez-Barrueco Jose M Silva Weijia Zhang Stephen Hearn Olivier Elemento Navid Paknejad Katia Manova-Todorova Karl Welte Jacqueline Bromberg Hector Peinado David Lyden | 2014 | Cell Research2014，24，6： | 98 |
| 2 | Differential Protective Effects of Volatile Anesthetics against Renal Ischemia–Reperfusion Injury In Vivo显示文摘 | H Thomas Lee Ayuko Ota-Setlik Yulei Fu Samih H. Nasr Charles W. Emala | 2004 | Anesthesiology2004，，6： | 1 |
| 3 | Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes显示文摘Diabetes is among the top 10 causes of death in adults and caused approximately four million deaths worldwide in 2017.The incidence and prevalence of diabetes is predicted to increase.To alleviate this potentially severe situation,safer and more effective therapeutics are urgently required.Mice have long been the mainstay as preclinical models for basic research on diabetes,although they are not ideally suited for translating basic knowledge into clinical applications.To validate and optimize novel therapeutics for safe application in humans,an appropriate large animal model is needed.Large animals,especially pigs, are well suited for biomedical research and share many similarities with humans,including body size,anatomical features,physiology,and pathophysiology.Moreover,pigs already play an important role in translational studies,including clinical trials for xenotransplantation.Progress in genetic engineering over the past few decades has facilitated the development of transgenic animals,including porcine models of diabetes.This article discusses features that attest to the attractiveness of genetically modified porcine models of diabetes for testing novel treatment strategies using recent technical advances. | Masaki Nagaya Koki Hasegawa Ayuko Uchikura Kazuaki Nakano Masahito Watanabe Kazuhiro Umeyama Hitomi Matsunari Kenji Osafune Eiji Kobayashi Hiromitsu Nakauchi Hiroshi Nagashima | 2021 | World Journal of Diabetes2021，12，4： | 1 |
| 4 | Rabring7: A target protein for rob7 Small G protein显示文摘 | Kouichi Mizuno Ayuko Sakan Takuya Sasaki | 2005 | Methods Enzymol2005，403，： | 1 |
| 5 | The relationship between surface tension and the industrial performance of water-soluble polymers prepared from acid hydrolysis lignin, a saccharification by-product from woody materials显示文摘 | Yasuyuki Matsushita Masanori Imai Ayuko Iwatsuki | 2008 | Bioresource Technology2008，99，： | 1 |
| 6 | Expression of ephrin-B1 in hepatocellular carcinoma: possible involvement in neovascularization显示文摘 | Yoshiyuki Sawai Shinji Tamura Koji Fukui Nobuyuki Ito Kazuho Imanaka Ayuko Saeki Shigeru Sakuda Shinichi Kiso Yuji Matsuzawa | 2003 | Journal of Hepatology2003，，6： | 1 |
| 7 | Fibroblast growth factor-2 stimulates adipogenic differentiation of human adipose-derived stem cells 显示文摘 | Natsuko Kakudo Ayuko Shimotsuma Kenji Kusumoto | 2007 | Biochemical and Biophysical Research Communications2007，359，： | 1 |
| 8 | Relation of oral 1α-hydroxy vitamin D 3 to the progression of aortic arch calcification in hemodialysis patients显示文摘 | Tetsuya Ogawa Hideki Ishida Mayuko Akamatsu Nami Matsuda Ayuko Fujiu Kyoko Ito Yoshitaka Ando Kosaku Nitta | 2010 | Heart and Vessels2010，，1： | 1 |
| 9 | Blockade of MEK/ERK signaling enhances sunitinib-induced growth inhibition and apoptosis of leukemia cells possessing activating mutations of the FLT3 gene显示文摘 | Chie Nishioka Takayuki Ikezoe Jing Yang Ayako Takeshita Ayuko Taniguchi Naoki Komatsu Kazuto Togitani H. Phillip Koeffler Akihito Yokoyama | 2007 | Leukemia Research2007，，6： | 1 |
| 10 | Structural Basis forMultimeric Heme Complexation through a Specific Protein-Heme Interac-tion显示文摘 | MASATO WATANABE Y T AYUKO SUENAGA | 2008 | J Biol Chem2008，283，42： | 1 |
| 11 | 显示文摘 | Yasuyuki Matsushita Ayuko Iwatsuki Seiichi Yasuda | 2004 | The Japan Wood Research Society2004，50，： | 1 |
| 12 | 170 NMR relaxation study of dynamics of water molecules in aqueous mixtures of methanol, ethanol, and 1-propanol over a temperature range of 283 - 403 K 显示文摘 | Koji Yoshida Ayuko Kitajo Toshio Yamaguchi | 2006 | Journal of Molecular Liquids2006，125，： | 1 |
| 13 | Effects of temperature on photosynthesis and plant growth in the assimilation shoots of a rose 显示文摘 | Ayuko U Tadahiko M Amane M | 2008 | Soil Science and Plant Nutrition2008，54，： | 1 |
| 14 | A Krukenberg Tumor from an Occult Intramucosal Gastric Carcinoma Identified during an Autopsy显示文摘 | Yoshiaki Nakamura Ayako Hiramatsu Takafumi Koyama Yu Oyama Ayuko Tanaka Koichi Honma Yoshihito Yokoyama | 2014 | Case Reports in Oncological Medicine2014，，： | 1 |
| 15 | Intermittent light irradiation with second-or hour-scale periods controls anthocyanin production by strawberry cells显示文摘 | HIROYUKI K AYUKO M NAOYUKI O | 2000 | Enzyme and Microbial Technology2000，26，： | 1 |
| 16 | Effects of temperature on photosynthesis and plant growth in the assimilation shoots of a rose 显示文摘 | AYUKO U TADAHIKO M AMANE M | 2008 | Soil Sci Plant Nutrition2008，54，： | 1 |
| 17 | 日本鹿儿岛湾真鲷的资源评估和增殖策略显示文摘通过世代分析对1990年至2002年鹿儿岛湾真鲷(Pagrus major)自然种群和放流种群的种群大小进行了评估,评估模型考虑了渔业资源管理和增殖放流措施。结果表明放流种群的规模有所减少,而自然种群的规模维持不变。真鲷自然种群的捕获量日趋减少,而放流种群的捕获量已超过50吨。研究结果表明增殖700000—800000尾真鲷种苗与其50吨的捕捞量相协调。在各种捕获量和放流量情况下,采用种群动力学模型预测了2017年真鲷的捕获量,其结果表明提高放流真鲷的数量能增加其捕获量。 | 赵炳然 SHISHIDOU Hirotoshi TAKIMOTO Ayuko OBATA Yasuhiro HAMASAKI Katsuyuki KITADA Shuichi | 2013 | 渔业信息与战略2013，28，4： | 1 |
| 18 | Ca- thode properties of Mn-doped inverse spinels for Li-ion bat- tery显示文摘 | Ayuko Kitajou Jun Yoshida Shinji Nakanishi | 2013 | J Power Sources2013，244，： | 1 |
| 19 | Oncostatin M Gene Therapy Attenuates Liver Damage Induced by Dimethylnitrosamine in Rats显示文摘 | Tetsuhiro Hamada Ayuko Sato Tadamichi Hirano Takashi Yamamoto Gakuhei Son Masayuki Onodera Ikuko Torii Takashi Nishigami Minoru Tanaka Atsushi Miyajima Shuhei Nishiguchi Jiro Fujimoto Tohru Tsujimura | 2007 | The American Journal of Pathology2007，，3： | 1 |
| 20 | 17O NMR relaxation study of dynamics of water molecules in aqueous mixtures of methanol,ethanol,and 1-propanol over a temperature range of 283-403 K显示文摘 | Koji Yoshida Ayuko Kitajo Toshio Yamaguchi | 2006 | Journal of Molecular Liquids2006，125，2： | 1 |
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