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| 1 | Heteromeric and Homomeric Geranyl Diphosphate Synthases from Catharanthus roseus and Their Role in Monoterpene Indole Alkaloid Biosynthesis显示文摘Catharanthus roseus 是二很重要的 monoterpene 吲哚碱(MIA ) 的唯一的来源反癌症代理人:vinblastine 和长春新碱。MIA 拥有萜烯和分别地从 terpenoid 和 shikimate 小径导出的吲哚一半。Geranyl diphosphate (GPP ) ,入口点到萜烯一半的形成,由 GPP synthase (GPPS ) 是 isopentenyl diphosphate (IPP ) 和 dimethylallyl diphosphate (DMAPP ) 的冷凝作用的一个产品。这里,我们报导与顺序类似编码蛋白质到大子单元(CrGPPS.LSU ) 和 heteromeric GPPS,和 homomeric 的小子单元(CrGPPS.SSU ) 的三基因 GPPS。CrGPPS.LSU 是生产 GPP 和 geranyl geranyl diphosphate (GGPP ) 的 bifunctional 酶, CrGPPS.SSU 是不活跃的,而 CrGPPS 是形成 GPP 的 homomeric 酶。在 Escherichia coli 的两个子单元的合作表示与生产仅仅 GPP 的提高的活动导致了 heteromeric 酶。当 CrGPPS.LSU 和 CrGPPS 在更旧、更年轻的叶子显示出更高的表示时,分别地, CrGPPS.SSU 显示出一个增加的趋势并且逐渐地减少了。叶子的甲基 jasmonate (MeJA ) 处理显著地导致了仅仅 CrGPPS.SSU 的表示。而 CrGPPS 是 mitochondrial, GFP 本地化显示 CrGPPS.SSU 是 plastidial。在 C 的 AmGPPS.SSU 的短暂 overexpression。roseus 叶子导致了增加的 vindoline, vinblastine 和长春新碱的立即的 monomeric 先锋。尽管 C。roseus 有 heteromeric 和 homomeric GPPS 酶,我们的结果含有有为 MIA 生合成调整 GPP 流动的 CrGPPS.SSU 的仅仅 heteromeric GPPS 的参与。 | Avanish Rai Shachi S. Smita Anup Kumar Singh Karuna Shanker Dinesh A. Nagegowda | 2013 | Molecular Plant2013，6，5： | 20 |
| 2 | Sudden sensorineural hearing loss-A contemporary review of management issues显示文摘Sudden sensorineural hearing loss(SSNHL)is an enigmatic entity,with obscure pathophysiology and debatable efficacy of the treatment agents used.An underlying cause is identified in only 10-15%of cases.The management of the remaining patients,classified as‘idiopathic’,is empirical,and is conventionally with systemic steroids,vasodilator therapy,rheological agents,and antioxidants,to list a few amongst the host of the agents employed for the treatment.The availability of conflicting outcomes and lack of conclusive evidence has resulted in the propagation of consensus-based treatment protocols.In the present review,we discuss the various controversial issues and newer developments in the management of idiopathic SSNHL.The current review aims to present a narrative outlook of the updated evidence base available from PUBMED,augmented with relevant designated publications. | Anup Singh David Victor Kumar Irugu | 2020 | Journal of Otology2020，15，2： | 11 |
| 3 | Value of diffusion-weighted imaging in distinguishing pancreatic carcinoma from mass-forming chronic pancreatitis: a meta-analysis显示文摘 | Niu Xiangke Sushant Kumar Das Anup Bhetuwal Xiao Yingquan Sun Feng Zeng Lichuan Wang Wenxuan Yang Hanfeng Yang Hanyu | 2014 | Chinese Medical Journal2014，，19： | 11 |
| 4 | Nerve-sparing robot-assisted radical prostatectomy:Current perspectives显示文摘Robotic-assisted radical prostatectomy(RARP)is the current standard of care with long term cure in organ-confined disease.The introduction of nerve-sparing(NS)to standard RARP has shown positive results in terms of functional outcomes in addition to the oncological outcomes.This article reviews the current perspectives of NS-RARP in terms of applied anatomy of the prostatic fascial planes,the neurovascular bundle(NVB),various NS techniques and postoperative functional outcomes.A non-systematic review was done using PubMed,Embase and Medline databases to retrieve and analyse articles in English,with following keywords“prostate cancer”,“robotic radical prostatectomy”,“nerve-sparing”.The Delphi method was used with an expert panel of robotic surgeons in urology to analyse the potency outcomes of various published comparative and non-comparative studies.The literature has shown that NS-RARP involves various techniques and approaches while there is a lack of randomized studies to suggest the superiority of one over the other.Variables such as preoperative risk assessments,baseline potency,surgical anatomy of individual patients and surgeons’expertise play a major role in the outcomes.A tailored approach for each patient is required for applying the NS approach during RARP. | Anup Kumar Vipul RPatel Sridhar Panaiyadiyan Kulthe Ramesh Seetharam Bhat Marcio Covas Moschovas Brusabhanu Nayak | 2021 | Asian Journal of Urology2021，8，1： | 4 |
| 5 | Adansonia digitata L.(baobab):a review of traditional information and taxonomic description显示文摘Adansonia digitata L.(Malvaceae) is commonly known as baobab tree native to Africa.Baobab is a multi-purpose tree which offers protection and provides food,clothing and medicine as well as raw material for many useful items.The fruit pulp,seeds,leaves,flowers.roots,and bark of baobab are edible and they have been studied by scientists for their useful properties.The fruit pulp have very high vitamin C.calcium,phosphorus,carbohydrates,fibers,potassium,proteins and lipids content,which can be used in seasoning as an appetizer and also make juices.Seeds contain appreciable quantities of phosphorus,magnesium,zinc,sodium,iron,manganese,whereas they have high levels of lysine,thiamine,calcium and iron.Baobab has numerous biological properties including antimicrobial,anti-malarial,diarrhoea,anaemia,asthma,antiviral,anti-oxidant and anti-inflammatory activities amongst others.Phytochemical investigation revealed the presence of flavonoids.phytosterols.amino acids,fatty acids,vitamins and minerals.The review summarizes the information on various aspects of traditional information,taxonomic description,medicinal properties and importantly nutritional value. | Jitin Rahul Manish Kumar Jain Shishu Pal Singh Rakesh Kant Kama Anuradha Aliya Naz Anup Kumar Gupta Sujeet Kumar Mrityunjay | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，1： | 4 |
| 6 | Study of morphologic variability of incudostapedial angle and its relation with temporal bone pneumatization显示文摘Introduction:Optimal sound transmission across the ossicular chain is dependent on the appropriate alignment of the middle ear ossicles.Incudostapedial joint(ISJ)is conventionally considered to be at right angle.Objective:We intended to study the ISJ anatomy and the impact of temporal bone pneumatization on the same.Methods:In a cadaveric study comprising of 47 human temporal bones,canal wall down mastoidectomy was carried out under microscopic guidance keeping the ossicular chain intact.The morphology of ISJ was recorded and analysed with respect to the pneumatization status of the temporal bone.The data analysis was performed using statistical software Stata version 12.0.Results:The mean ISJ angle for the 47 bones was 90.5^0(SD-15^0;range:54^0-122^0).The mean angle in well pneumatized bones was 93.7^0(SD-16.5;Range:54°-122^0)and in sclerotic mastoids was 88.7^0(SD-14;Range:68°-118^0).The difference in the ISJ angle in these two conditions was not statistically significant(p=0.27).The mean angle was found to be significantly more obtuse in the cases with partially eroded ISJ(111.4^0{SD-8.8;range:100.3^0-221.9^0};p=0.0001)and in the cases with an‘adherent/tilted morphology’of the stapes suprastructure with the promontory(mean-95.8^0(SD-13.8;range:70.7^0-120.4^0);p-<0.00001).Conclusion:The ISJ angle shows considerable variations.This variability needs to be taken into account when undertaking middle ear reconstructive procedures,specifically the ones involving the stapes footplate.The mastoid pneumatization does not appear to have an impact on the ISJ angle. | Anup Singh David Victor Kumar Irugu Rajeev Kumar Hitesh Verma Anandita Gupta Abha Kumari | 2020 | Journal of Otology2020，15，2： | 3 |
| 7 | Hirschsprung's disease:Is there a relationship between mast cells and nerve fibers?显示文摘AIM:To define the topography of mast cells and their numbers in cases of Hirschsprung's disease(HD)and non-HD,assess neural hypertrophy using imaging software and to study the relationship between mast cells and nerve fibers.METHODS:HE stained sections of 32 cases of chronic constipation in the age group of 0-14 years were reviewed for ganglion cells.AChE staining was performed on frozen sections of colonic and rectal biopsies.Based on their findings cases were divided into HD and non-HD and mast cells stained by toluidine blue were evaluated.Image analysis by computerized software was applied to S-100 stained sections for assessment of neural hypertrophy.RESULTS:Difference between number of mast cells in HD group(mean=36.44)and in non-HD group(mean =14.79)was statistically significant.Image analysis morphometry on S-100 stained sections served as a useful adjunct.The difference between number,size,and perimeter of the nerve fibers between HD and non-HD group was statistically significant.CONCLUSION:Mast cells are significantly increased in HD and their base line values are much higher in Indian children than that reported in Western literature.Their role in HD needs further research.Morphometry of S-100 stained nerve fibers is a useful adjunct to conventional methods for diagnosis of HD. | Amit Kumar Yadav Kiran Mishra Anup Mohta Sarla Agarwal | 2009 | World Journal of Gastroenterology2009，15，12： | 2 |
| 8 | Designing of an all-optical time division multiplexing scheme with the help of nonlinear material based tree-net architecture显示文摘In the field of optical interconnecting network and in super fast photonic computing system, the tree architecture and optical nonlinear materials can play a significant role. Nonlinear optical material may find important uses in optical switching. Optical switch using nonlinear material makes it possible for one optical signal to control and switch another optical signal through nonlinear interaction in a material. In this communication such materials have been successfully exploited to design an all-optical tree-net architecture, which can be utilized for time division multiplexing scheme in all-optical domain. | Jitendra Nath Roy Anup Kumar Maiti Sourangshu Mukhopadhyay | 2006 | Chinese Optics Letters2006，4，8： | 2 |
| 9 | MTSS: multi-path traffic scheduling mechanism based on SDN显示文摘Large-scale and diverse businesses based on the cloud computing platform bring the heavy network traffic to cloud data centers.However,the unbalanced workload of cloud data center network easily leads to the network congestion,the low resource utilization rate,the long delay,the low reliability,and the low throughput.In order to improve the utilization efficiency and the quality of services(QoS)of cloud system,especially to solve the problem of network congestion,we propose MTSS,a multi-path traffic scheduling mechanism based on software defined networking(SDN).MTSS utilizes the data flow scheduling flexibility of SDN and the multi-path feature of the fat-tree structure to improve the traffic balance of the cloud data center network.A heuristic traffic balancing algorithm is presented for MTSS,which periodically monitors the network link and dynamically adjusts the traffic on the heavy link to achieve programmable data forwarding and load balancing.The experimental results show that MTSS outperforms equal-cost multi-path protocol(ECMP),by effectively reducing the packet loss rate and delay.In addition,MTSS improves the utilization efficiency,the reliability and the throughput rate of the cloud data center network. | XU Xiaolong CHEN Yun HU Liuyun KUMAR Anup | 2019 | Journal of Systems Engineering and Electronics2019，30，5： | 2 |
| 10 | RFID security and privacy concerns显示文摘 | Srinivasan S Aggarwal Akshai Kumar Anup | 2006 | WSEAS Transactions on Communications2006，5，2： | 1 |
| 11 | An experimental and theoretical investigation on torrefaction of a large wet wood particle显示文摘 | Prabir Basu Anup Kumar Sadhukhan Parthapratim Gupta | 2014 | Bioresource Technology2014，159，2： | 1 |
| 12 | Modelling of pyrolysis of coal–biomass blends using thermogravimetric analysis显示文摘 | Anup Kumar Sadhukhan Parthapratim Gupta Tripurari Goyal Ranajit Kumar Saha | 2008 | Bioresource Technology2008，，17： | 1 |
| 13 | Comprehensive process maps to synthesize high density plasma sprayed alu- minum oxide composite coatings with varying carbon nano- tube content显示文摘 | Anup Kumar Keshri Riken Patel | 2010 | Surf Coat Techn2010，205，： | 1 |
| 14 | Pediatric intrahepatic bile duct adenoma-rare liver tumor: A case report显示文摘BACKGROUND Intrahepatic bile duct adenoma(BDA)is one of the rarest of the rare benign tumors of the liver in the pediatric age group.It arises from the epithelial lining of intrahepatic bile ducts.The overall incidence of BDA is 1.3%of all primary benign liver tumors.Few case reports of this rare tumor occurring in adult population are present in the literature and to date,only one pediatric case has been reported worldwide.CASE SUMMARY An 18-month-old male child presented with chief complaints of mass per abdomen for 8 mo.Computerized tomography abdomen revealed a well-defined exophytic solid tumor arising from the posteroinferior margin of the right lobe of the liver with heterogenous enhancement and cystic changes,suggesting a suspicion of hepatoblastoma.Non-anatomical liver resection was done and a tumor of 10 cm×9.5 cm was excised.Histopathology of the specimen was conclusive with the diagnosis of intrahepatic bile duct adenoma,which was further supported by immunohistochemistry panel testing.The post-operative period was uneventful.On follow-up,the child was doing well and had no postoperative complication.CONCLUSION Intrahepatic bile duct adenoma in children is very rare and to date only one case has been reported.This is the second pediatric case of intrahepatic bile duct adenoma in the world.Additionally this is the first ever case of such a large tumor presenting in a child. | Anup Kumar Roy Nrityen Nath Das | 2019 | World Journal of Gastrointestinal Surgery2019，11，11： | 1 |
| 15 | Selective removal of anomeric O-acetate groups in carbohydrates using HClO4-SiO2显示文摘 | Pallavi Tiwari Anup Kumar Misra | 2006 | Tetrahedron Letters2006，47，21： | 1 |
| 16 | Effi ciency of the Indian leatherfi rms: some results obtained using the two conventional methods显示文摘 | Anup Kumar Bhandari Pradip Maiti | 2012 | Journal Productivi- ty Analysis2012，，37： | 1 |
| 17 | Laparoscopic nephroplication and nephropexy as an adjunct to pyeloplasty in UPJO with giant hydronephrosis显示文摘 | Lokesh Jindal Anup Kumar Gupta Faiz Mumtaz Rani Sunder A. K. Hemal | 2006 | International Urology and Nephrology (-)2006，，3： | 1 |
| 18 | Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer显示文摘 | Meenu Jain Anup Raj Tilak Rohit Upadhyay Ashwani Kumar Balraj Mittal | 2008 | Toxicology and Applied Pharmacology2008，，2： | 1 |
| 19 | CuO nano-whiskers: Electrodeposition, Raman analysis, photoluminescence study and photocatalytic activity显示文摘 | Nillohit Mukherjee Bibhutibhushan Show Swarup Kumar Maji Utpal Madhu Sanjib Kumar Bhar Bibhas Chandra Mitra Gobinda Gopal Khan Anup Mondal | 2011 | Materials Letters2011，，21： | 1 |
| 20 | Modelling of combustion characteristics of high ash coal char particles at high pressure: Shrinking reactive core model显示文摘 | Anup Kumar Sadhukhan Parthapratim Gupta Ranajit Kumar Saha | 2009 | Fuel2009，，1： | 1 |
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