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| 1 | Improving efficiency of sow productivity: nutrition and health显示文摘This reviews research focused to understand the nutrient requirement and balance to meet the needs of fetal growth,mammary growth,and milk production.This summary will handle how feeding strategies can be adjusted according to the nutrient needs for a sow to enhance productivity and health.Most research data used in this summary are based on the studies conducted by the authors between 1996 and 2013.Nutrient requirements of sows are affected by stage of gestation and parity of sows.Dietary antioxidant concentrations need to be re-evaluated for its sufficiency in sow diets especially to prevent excessive oxidative stress during late gestation and lactation.When feeding sows,consideration of phase feeding of gestating sows and parity feeding of lactating sows could enhances production longevity and health of sows.Use of selected nutrients and additives seems to help productivity and health of sows. | Sung Woo Kim Alexandra C Weaver Yan Bin Shen Yan Zhao | 2013 | Journal of Animal Science and Biotechnology2013，4，3： | 24 |
| 2 | Apparent diffusion coefficient values of normal testis and variations with age显示文摘在阴囊的病理的评估的散开加权的磁性的回声成像(DWI ) 的实用性最近被报导了。当解释正常阴囊的解剖和病理时,阴囊的明显的散开系数(模数转换器) 珍视的正常和他们有年龄的变化的一本标准参考书是必要的。我们用 DWI 评估了 147 个正常睾丸,包括从 20-39 年(组 1 ) 的 53 个人的 71 个睾丸,从 40-69 年(组 2 ) 的 42 个人的 67 个睾丸和从比 70 年(组 3 ) 老的六个人的九个睾丸。DWI 沿着轴的飞机被执行,用单个射击, multislice 纺纱回响平面散开脉搏顺序和 0 和 900 s 公里 −2 的 b 值。正常阴囊的实质的模数转换器价值的平均数和标准差独立为每个年龄组被计算。柱子 hoc 分析(Dunnett T3 ) 跟随的变化(ANOVA ) 的分析被用于统计目的。模数转换器价值(×正常阴囊的织物的 10 −3 公里 2 s −1) 在年龄组之中是不同的(组 1:1.08 ±0.13;组 2:1.15 ±0.15 和组 3:1.31 ±0.22 ) 。ANOVA 在年龄组之中在吝啬的模数转换器揭示了差别(F = 11.391, P <0.001 ) 。波斯特 hoc 分析显示出组之间的差别 1 和 2 (P = 0.008 ) 并且在组之间 1 和 3 (P = 0.043 ) ,然而并非在组之间 2 和 3 (P = 0.197 ) 。我们的调查结果建议正常阴囊的织物的模数转换器价值与推进年龄增加。 | Athina C Tsili Dimitrios Giannakis Anastasios Sylakos Alexandra Ntorkou Loukas G Astrakas Nikolaos Sofikitis Maria I Argyropoulou | 2014 | Asian Journal of Andrology2014，16，3： | 8 |
| 3 | Cold-inducible RNA-binding protein activates splenic T cells during sepsis in a TLR4-dependent manner显示文摘Cold-inducible RNA-binding protein (CIRP) is a novel inflammatory mediator that stimulates the release of proinflammatory cytokines from macrophages in sepsis. Given the immune dysregulation that characterizes sepsis, the effect of CIRP on other immune cells is an area of increasing interest that has not yet been studied. In the present study, we hypothesized that extracellular CIRP promotes activation of T lymphocytes in the spleen during sepsis. We observed that mice subjected to sepsis by cecal ligation and puncture showed significantly higher expression of the early activation markers CD69 and CD25 at 20 h on CD4+ splenic T cells, and significantly higher CD69 expression on CD8+ splenic T cells compared with sham-operated controls. Furthermore, at 20 h after receiving intravenous injection of recombinant murine CIRP (rmCIRP, 5 mg/kg body weight (BW)) or PBS (vehicle), those mice receiving rmCIRP showed significantly increased expression of CD69 and CD25 on both CD4+ and CD8+ splenic T cells. This effect, however, was not seen in TLR4-deficient mice after rmCIRP injection. In addition, treatment with CIRP predisposed CD4+ T cells to a Th1 hyperinflammatory response profile, and influenced CD8+ T cells toward a cytotoxic profile. Taken together, our findings indicate that CIRP is a proinflammatory mediator that plays an important role in T-cell dysregulation during sepsis in a TLR4-dependent manner. | Alexandra C Bolognese Archna Sharma Weng-Lang Yang Jeffrey Nicastro Gene F Coppa Ping Wang | 2018 | Cellular & Molecular Immunology2018，15，1： | 4 |
| 4 | Rationale for the potential use of mesenchymal stromal cells in liver transplantation显示文摘Mesenchymal stromal cells(MSCs) are multipotent and self-renewing cells that reside essentially in the bone marrow as a non-hematopoietic cell population, but may also be isolated from the connective tissues of most organs. MSCs represent a heterogeneous population of adult, fibroblast-like cells characterized by their ability to differentiate into tissues of mesodermal lineages including adipocytes, chondrocytes and osteocytes. For several years now, MSCs have been evaluated for their in vivo and in vitro immunomodulatory and ‘tissue reconstruction' properties, which could make them interesting in various clinical settings, and particularly in organ transplantation. This paper aims to review current knowledge on the properties of MSCs and their use in pre-clinical and clinical studies in solid organ transplantation, and particularly in the field of liver transplantation. The first available clinical data seem to show that MSCs are safe to use, at least in the medium-term, but more time is needed to evaluate the potential adverse effects of long-term use. Many issues must be resolved on the correct use of MSCs. Intensive in vitro and pre-clinical research are the keys to a better understanding of the way that MSCs act, and to eventually lead to clinical success. | Morgan Vandermeulen Céline Grégoire Alexandra Briquet Chantal Lechanteur Yves Beguin Olivier Detry | 2014 | World Journal of Gastroenterology2014，20，44： | 2 |
| 5 | A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human Hepatocytes显示文摘 | Sibylle Haid Alexandra Novodomská Juliane Gentzsch Christina Grethe Silvia Geuenich Dorothea Bankwitz Patrick Chhatwal Beate Jannack Thierry Hennebelle Francois Bailleul Oliver T. Keppler Marion Poenisch Ralf Bartenschlager Céline Hernandez Matthieu Lemas | 2012 | Gastroenterology2012，，1： | 2 |
| 6 | Bone mineral content and density in the humerus of adult myostatin - deficient mice显示文摘 | MW Hamrick Alexandra C McPherron C O Lovejoy | 2002 | Calcif Tissue Int2002，71，1： | 1 |
| 7 | Thermochemistry and aqueous solubilities of hydrotalcitelike solids显示文摘 | Rama Kumar A Alexandra N Hillary T B William H C | | 0，，5568： | 1 |
| 8 | Obtaining of monodisperse particles through soap-free polymerization in the presence of C60显示文摘 | Edina R Alexandra M Cosmin C | | 0，，： | 1 |
| 9 | Protein kinase C structure, function and regulation显示文摘 | Alexandra C Newton | 1995 | J Biol Chem1995，270，28： | 1 |
| 10 | Double muscling in cattle due to mutations in the myostatin gene显示文摘 | Alexandra C Mcpherron Se -Jin Lee | 1997 | Genetics1997，94，12： | 1 |
| 11 | Suppression of body fat accumulation in myostatin-deficient mice显示文摘 | Alexandra C McPherron AC | 2002 | J Clin Invest2002，109，5： | 1 |
| 12 | Redundancy of myostatin and growth/differentiation factor 11function显示文摘 | Alexandra C Mcpherron Thanh V Huynh Se - Jln Lee | 2009 | BMC2009，，： | 1 |
| 13 | Lay- er-by-layer engineered capsules and their applications 显示文摘 | ANGUS P R J CHRISTINA C ALEXANDRA S A | 2006 | Curr Opin Colloidln2006，11，4： | 1 |
| 14 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 15 | Chemical routes for the transformation of biomass into chemicals 显示文摘 | Avelino C Sara I Alexandra V | 2007 | Chem Rev2007，107，6： | 1 |
| 16 | GDF-3 and GDF-9:Two new mem-bers of the transforming growth factor-β superfamily containing a never pattern of cysteines显示文摘 | Alexandra C McPherron A C Lee S J | 1993 | J Biol Chem1993，268，： | 1 |
| 17 | Phytoplankton dynamics in a coastal saline lake显示文摘 | PEDRO M ALEXANDRA C ANA B | 2003 | Acta Oecologica2003，24，： | 1 |
| 18 | Limited role of secretedaspartyl proteinases Sap1 to Sap6 in Candida albicans virulenceand host immune response in murine hematogenously dissemina-ted candidiasis显示文摘 | Alexandra C Ulrich L Luzia T | 2010 | Infect Immun2010，78，11： | 1 |
| 19 | Development of a method to produce freeze-dried cubes from 3 pacific salmon species 显示文摘 | Charles C Alexandra C M Olivera D N | 2010 | Journal of Food Science2010，75，5： | 1 |
| 20 | Suppression of body fat accumulation in myostatin-deficient mice显示文摘 | Se-Jin Lee MePherron Alexandra C | 1997 | J Clin Invest1997，，109： | 1 |
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