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| 1 | Comparison of sperm retrieval and reproductive outcome in azoospermic men with testicular failure and obstructive azoospermia treated for infertility显示文摘我们估计了精子检索和 intracytoplasmic 精子注射结果的率,包括构思的婴儿的新生的侧面,在有阴囊的失败的人。三 -- 经历了微解剖的阴囊的精子抽取的有阴囊的失败的 165 个人在这研究被包括。我们把他们的结果与 40 作比较为注射使用了施主精子由于的有阴囊的失败的人与妨碍的精子缺乏没有通过检索,和 146 个人经历了经皮的精子检索。在阴囊的失败的检索率是 41.4% ,并且结果比妨碍的精子缺乏低(100% ;调整机会比率:0.033;95% CI:0.007-0.164;P <0.001 ) 。在精子注射以后的实时出生率与施主精子相比在有阴囊的失败(19.9%) 的人是更低的(37.5% ;调整或:0.377 (95% CI:0.233-0.609, P <0.001 )) 并且妨碍的精子缺乏(34.2% ;调整或:0.403 (95% CI:0.241-0.676, P = 0.001 ) 。构思的婴儿的新生的参数不在这些组之中是显著地不同的。我们断定在检索上获得精子并且在 intracytoplasmic 精子注射(ICSI ) 以后完成实时出生的机会与阴囊的失败在人被减少。在精子注射不似乎被阴囊的失败否定地影响以后,婴儿的侧面怀孕了。 | Sandro C Esteves Christina Prudencio Bill Seol Sidney Verza jr Christopher Knoedler Ashok Agarwal | 2014 | Asian Journal of Andrology2014，16，4： | 9 |
| 2 | Transanal polypectomy using single incision laparoscopic instruments显示文摘Transanal excision of rectal polyps with laparoscopic instrumentation and a single incision laparoscopic port is a novel technique that uses technology originally developed for abdominal procedures from the natural orifice of the rectum. Transanal endoscopic microsurgery (TEM) is a well established surgical approach for certain benign or early malignant lesions of the rectum, under specific indications. Our technique is a hybrid technique of transanal surgery, a reasonable method for polyp resection without the need of the sophisticated and expensive instrumentation of TEM which can be applied whenever endoscopic or conventional transanal surgical removal is not feasible. | Dimitrios Dardamanis Dimitrios Theodorou George Theodoropoulos Andreas Larentzakis Maria Natoudi Georgia Doulami Christina Zoumpouli Haridimos Markogiannakis Stylianos Katsaragakis George C Zografos | 2011 | World Journal of Gastrointestinal Surgery2011，3，4： | 6 |
| 3 | Circulating autoantibodies to endogenous erythropoietin are associated with chronic hepatitis C virus infection-related anemia显示文摘BACKGROUND: Chronic hepatitis C virus(HCV) infection is associated with autoimmune phenomena and is often complicated by anemia. Circulating autoantibodies to endogenous erythropoietin(anti-EPO) have been detected in patients with chronic viral infections and were correlated to anemia. The present study aimed to determine anti-EPO prevalence in patients with chronic HCV infection and investigate its possible association with anemia.METHODS: Ninety-three consecutive patients(62 males and 31 females) with chronic HCV infection, who had never received antiviral therapy or recombinant EPO, were enrolled in the study. Circulating anti-EPO were detected in the serum by using an ELISA assay. Quantitative determination of serum EPO levels was done by radioimmunoassay. HCV RNA viral load measurement and genotype sequencing were also performed.RESULTS: Circulating anti-EPO were detected in 10.8% of HCV-infected patients and the prevalence of anti-EPO was significantly higher in patients with anemia(19.4% vs 5.3%, P=0.040) compared to that in those without anemia. Compared to anti-EPO negative cases, anti-EPO positive patients had higher frequency of anemia(70.0% vs 34.9%, P=0.030), lower EPO concentrations(median 16.35 vs 30.65 m U/m L, P=0.005), and higher HCV RNA viral load(median 891.5×103 vs 367.5×103 IU/m L, P=0.016). In multivariate regression analysis the presence of anti-EPO remained an independent predictor of anemia(adjusted OR: 14.303, 95% CI: 1.417-36.580, P=0.024). EPO response to anemia was less prominent among anti-EPO positive patients(P=0.001).CONCLUSIONS: Circulating anti-EPO are detected in a significant proportion of treatment-na?ve HCV-infected patients and are independently associated with anemia, suggesting a further implication of autoimmunity in the pathophysiology of HCV-related anemia. | Aristotelis Tsiakalos Theoharis Voumvas Alexandros Psarris Christina K Oikonomou Dimitrios C Ziogas Ioannis Ketikoglou Grigorios Hatzis Nikolaos V Sipsas | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，3： | 4 |
| 4 | Twenty-five years of research on the effects of exercise training in breast cancer survivors:A systematic review of the literature显示文摘AIM:To investigate the role of exercise training the past 25 years on major physiological-psychological outcomes studied thus far in this patient population.METHODS:Pub Med, Medline Plus, the Cochrane Library, Web of Science, SportD iscus, Embase, Scorpus, and Google Scholar were searched from September to November 2013 to identify exercise training studies that used objective measurements of fitness and/or patient reported outcomes assessed pre and post-exercise training with statistical analyses performed in at least one of the following outcome measurements:Cardiorespiratory function, body composition, muscular strength, fatigue, depression, and overall quality of life. Five reviewers independently identified the studies that met the criteria for the review and discrepancies were resolved by consensus among all authors.RESULTS:Fifty-one studies were included in this review with 5 from the period between 1989-1999, 11 from 2000-2006, and 35 from 2007-2013. The evolution of study designs changed from aerobic only exercise training interventions(1989-1999), to a combination of aerobic and resistance training(2000-2006), to studies including an arm of resistance training or examining the effects of resistance training as the main mode of exercise(2007-2013). Overall, the benefits of exercise showed improvements in cardiorespiratory function, body composition, strength, and patient reported outcomes including fatigue, depression, and quality of life.CONCLUSION:Exercise training appears to be safe for most breast cancer patients and improvements in physiological, psychological, and functional parameters can be attained with regular participation in moderate intensity exercise. | Claudio L Battaglini Robert C Mills Brett L Phillips Jordan T Lee Christina E Story Marcelo GB Nascimento Anthony Carl Hackney | 2014 | World Journal of Clinical Oncology2014，5，2： | 3 |
| 5 | Dysfunctions of the Iga system:a common link between intestinal and renal diseases显示文摘Immunoglobulin A(Iga)-isotype antibodies play an important role in immunity owing to their structure,glycosylation,localization and receptor interactions.Dysfunctions in this system can lead to multiple types of pathology.This review describes the characteristics of Iga and discusses the involvement of abnormalities in the Iga system on the development of celiac disease and Iga nephropathy. | Christina Papista Laureline Berthelot Renato C Monteiro | 2011 | Cellular & Molecular Immunology2011，8，2： | 3 |
| 6 | A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human Hepatocytes显示文摘 | Sibylle Haid Alexandra Novodomská Juliane Gentzsch Christina Grethe Silvia Geuenich Dorothea Bankwitz Patrick Chhatwal Beate Jannack Thierry Hennebelle Francois Bailleul Oliver T. Keppler Marion Poenisch Ralf Bartenschlager Céline Hernandez Matthieu Lemas | 2012 | Gastroenterology2012，，1： | 2 |
| 7 | Therapeutic plasma exchange in liver failure显示文摘The multi-organ failure syndrome associated with acute and acute-on-chronic liver failure(ACLF)is thought to be mediated by overwhelming systemic inflammation triggered by both microbial and non-microbial factors.Therapeutic plasma exchange(TPE)has been proven to be an efficacious therapy in autoimmune conditions and altered immunity,with more recent data supporting its use in the management of liver failure.Few therapies have been shown to improve survival in critically ill patients with liver failure who are not expected to survive until liver transplantation(LT),who are ineligible for LT or who have no access to LT.TPE has been shown to reduce the levels of inflammatory cytokines,modulate adaptive immunity with the potential to lessen the susceptibility to infections,and reduce the levels of albumin-bound and water-bound toxins in liver failure.In patients with acute liver failure,high volume TPE has been shown to reduce the vasopressor requirement and improve survival,particularly in patients not eligible for LT.Standard volume TPE has also been shown to reduce mortality in certain sub-populations of patients with ACLF.TPE may be most favorably employed as a bridge to LT in patients with ACLF.In this review,we discuss the efficacy and technical considerations of TPE in both acute and acute-on-chronic liver failure. | Abimbola Chris-Olaiya Aanchal Kapoor Kristin S Ricci Christina C Lindenmeyer | 2021 | World Journal of Hepatology2021，13，8： | 2 |
| 8 | Pit-and trench-forming osteoclasts:a distinction that matters显示文摘Osteoclasts(OCs)seeded on bone slices either drill round pits or dig long trenches.Whereas pits correspond to intermittent resorption,trenches correspond to continuous and faster resorption and require a distinct assembly of the resorption apparatus.It is unknown whether the distinction between pits and trenches has any biological relevance.Using OCs prepared from different blood donors,we found that female OCs achieved increased resorption mainly through pit formation,whereas male OCs did so through trench formation.Trench formation went along with high collagenolytic activity and high cathepsin K(CatK)expression,thereby allowing deeper demineralization.A specific CatK inhibitor abrogated the generation of trenches,while still allowing the generation of pits.OCs obtained from bone marrow were more prone to generate trenches than those obtained from blood.Scanning electron microscopy of bone surfaces eroded in vivo showed trenches and pits of similar size as those made by OCs in culture.We conclude that the distinction between trench-and pit-forming OCs is relevant to the differences among OCs from different skeletal sites,different individuals,including gender,and results from differences in colIagenolytic power.This indicates a biological relevance and highlights the importance of discriminating between pits and trenches when assessing resorption. | Ditte MH Merrild Dinisha C Pirapaharan Christina M Andreasen Per Kjxrsgaard-Andersen Anas MJ Mùller Ming Ding Jean-Marie Delaissé Kent Sùe | 2015 | Bone Research2015，3，4： | 2 |
| 9 | Are urban green spaces optimally distributed to act as places for social integration? Results of a geographical information system (GIS) approach for urban forestry research显示文摘 | Christina G C Klaus S | 2004 | Forest Policy and Economics2004，6，： | 1 |
| 10 | Signaling in Equity Crowdfunding 显示文摘 | Ahlers GKC Douglas C Christina G | 2012 | Entrepreneurship Theory & Practice2012，，39： | 1 |
| 11 | Reproductive toxicity evaluation of dietary butyl benzyl phthalate(BBP)in rats显示文摘 | Rochelle W T Christina B M Melissa C M | 2004 | Reproductive Toxicology2004，18，： | 1 |
| 12 | Ageing, oxidative stress and cancer: paradigms in parallax显示文摘 | Ben Z Christopher C Christina Y | 2008 | Nature Reviews Cancer2008，8，11： | 1 |
| 13 | Are urban green spaces optimally distributed to act as places for social integration? Results of a geographical information system (GIS) approach for urban forestry research显示文摘 | CHRISTINA G C KLAUS S | 2004 | Forest Policy and Economics2004，，6： | 1 |
| 14 | Gene expression analysis of toll - like receptor path- ways in heterophils from genetic chicken lines that dif- fer in their susceptibility to salmonella enteritidis 显示文摘 | MICHAEL H K HSIN I C CHRISTINA L S | 2012 | Front Genet2012，3，： | 1 |
| 15 | Resistance to soybean aphid in early maturing soybean germplasm 显示文摘 | Mensah C Christina D F | 2005 | Crop Science2005，45，： | 1 |
| 16 | Expression of the Jaagsiekte sheep retrovirus envelope glycoprotein is sufficient to induce lung tumors in sheep 显示文摘 | Marco C Christina C Patrizia C | 2006 | J Virol2006，8，： | 1 |
| 17 | Using human perceptual categories for content-based retrieval from a medical image database显示文摘 | Chi R S Christina P Avinash C K | 2002 | Computer Vision and Image Understanding2002，88，3： | 1 |
| 18 | The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial显示文摘 | Colin Baigent Martin J Landray Christina Reith Jonathan Emberson David C Wheeler Charles Tomson Christoph Wanner Vera Krane Alan Cass Jonathan Craig Bruce Neal Lixin Jiang Lai Seong Hooi Adeera Levin Lawrence Agodoa Mike Gaziano Bertram Kasiske Robert Wal | 2011 | The Lancet2011，，9784： | 1 |
| 19 | Effects of Tai Chi on pre-landingmuscle response latency during stepping down while performing a concurrent mental task in older adults显示文摘 | William W N Tsang Christina W Y Hui C Siu N Fu | 2011 | European Journal of Applied Physiology2011，112，7： | 1 |
| 20 | HIV-1 integrase crosslinked oligomers are active in vitro显示文摘 | Aur lie F Christina C Cecile D | 2005 | Nucleic Acids Research2005，33，3： | 1 |
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