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| 1 | α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma显示文摘 | Jorge A. Marrero Ziding Feng Yinghui Wang Mindie H. Nguyen Alex S. Befeler Lewis R. Roberts K. Rajender Reddy Denise Harnois Josep M. Llovet Daniel Normolle Jackie Dalhgren David Chia Anna S. Lok Paul D. Wagner Sudhir Srivastava Myron Schwartz | 2009 | Gastroenterology2009,,1: | 3 |
| 2 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011,,1: | 2 |
| 3 | Mathematical Analysis and Simulation of the Neural Circuit for Locomotion in Lamnprey显示文摘 | Alex Lewis Silvia Scarpetta | 2004 | Phys Rev lett2004,198,: | 1 |
| 4 | Evolutionary games of cooperation: Insights through integration of theory and data显示文摘 | Hannah M. Lewis Alex J. Dumbrell | 2013 | Ecological Complexity2013,,: | 1 |
| 5 | A physics-based atmospheric and BRDF correction for Landsat data over mountainous terrain显示文摘 | Fuqin Li David L.B. Jupp Medhavy Thankappan Leo Lymburner Norman Mueller Adam Lewis Alex Held | 2012 | Remote Sensing of Environment2012,,: | 1 |
| 6 | Analytical and computational aspects of collaborative optimization显示文摘 | ALEX M N LEWIS M R | 2002 | AIAA Journal2002,40,2: | 1 |
| 7 | Conservative surgery to preserve o-varian function in patients with malignant ovarian germ cell tumors显示文摘 | Jeffrey JH Lewis CP Alex JC | 2000 | Cancer2000,89,2: | 1 |
| 8 | A phase II study of the heparanase inhibitor PI-88 in patients with advanced melanoma显示文摘 | Karl D. Lewis William A. Robinson Michael J. Millward Alex Powell Timothy J. Price Damien B. Thomson Euan T. Walpole Andrew M. Haydon Brian R. Creese Kaye L. Roberts John R. Zalcberg Rene Gonzalez | 2008 | Investigational New Drugs2008,,1: | 1 |
| 9 | 一个基于深度学习的眼病和肺炎两大类疾病的AI诊断系统显示文摘文章简介本研究开发了一个基于深度学习框架能诊断致盲性视网膜疾病的人工智能(AI)诊断工具。而且,该AI诊断工具还可用于诊断小儿肺炎。这是一项将AI应用于医疗领域的重磅研究成果,有望高精确诊断多种可治疗性疾病。在眼科治疗中,视网膜OCT(光学相干断层扫描)成像技术是最常用的诊断技术之一。 | Daniel S.Kermany Michael Goldbaum Wenjia Cai Carolina C.S.Valentim Huiying Liang Sally L.Baxter Alex McKeown Ge Yang Xiaokang Wu Fangbing Yan Justin Dong Made K.Prasadha Jacqueline Pei Magdalene Y.L.Ting Jie Zhu Christina Li Sierra Hewett Jason Dong Ian Ziyar Alexander Shi Runze Zhang Rui Hou William Shi Xin Fu Yaou Duan Viet A.N. Huu Cindy Wen Edward D. Zhang Charlotte L. Zhang Oulan Li Xiaobo Wang Michael A. Singer Xiaodong Sun Jie Xu Ali Tafreshi M. Anthony Lewis Huimin Xia 张康 | 2019 | 科学新闻2019,0,2: | 1 |
| 10 | Nat Methods:利用CRISPR-Cas9组合筛选发现癌症弱点显示文摘导致癌症的基因突变也会削弱癌细胞,从而使得人们有机会开发选择性地杀死它们同时不影响正常细胞的药物。这一概念被称作”合成致死性(synthetic lethality)”,这是因为这些药物仅对发生突变的(或者说合成的)细胞是致命性的。在一项新的研究中。来自美国加州大学圣地亚哥分校、加州大学旧金山分校、斯坦福大学和癌细胞图谱项目(Cancer Cell Map Initiative)的研究人员开发出一种新的方法来寻找合成致死性的基因组合。 | John Paul Shen, Ana Bojorquez-Gomez, Katherine Licon, Kristin Klepper, Daniel Pekin, Alex N Beckett, Kyle Salinas Sanchez, Jason F Kreisberg, Trey Ideker John Paul Shen, Trey Ideker, Prashant Mali John Paul Shen, Dongxin Zhao, Dan Du, Assen Roguev, Jason F Kreisberg, Nevan Krogan, Lei Qi, Trey Ideker, Prashant Mali Dongxin Zhao, Chih-Chung Kuo, Prashant Mali Roman Sasik, Amanda Birmingham, Aaron N Chang, Trey Ideker Jens Luebeck, Alex Thomas Alex Thomas, Chih-Chung Kuo, Nathan E Lewis Dan Du Assen Roguev, Nevan Krogan Nathan E Lewis Lei Qi | 2017 | 现代生物医学进展2017,17,17: | 1 |
| 11 | α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma显示文摘 | Jorge A. Marrero Ziding Feng Yinghui Wang Mindie H. Nguyen Alex S. Befeler Lewis R. Roberts K. Rajender Reddy Denise Harnois Josep M. Llovet Daniel Normolle Jackie Dalhgren David Chia Anna S. Lok Paul D. Wagner Sudhir Srivastava Myron Schwartz | 2009 | Gastroenterology2009,,1: | 1 |
| 12 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011,,1: | 1 |
| 13 | UNIFI鉴定未知中药成分 鉴定未知中药片剂申的化学成分及推测其所含药材显示文摘本文以未知物中药片剂,阐述了如何运用超高效液相色谱(ACQUITY UPLC I-Class)、四级杆飞行时间质谱(Xevo G2-S QTof)及UNIFI天然产物整体解决方案鉴定未知中药片剂中的化学成分并推测其所含药材,对未知物组分鉴定和可能药材推测的整体工作流程大大提高了未知中药体系组分定性工作的准确性及效率。 | 乔立瑞 Rob Lewis Alex Hooper James Morphet 谭晓杰 Kate Yu | 2014 | 实验与分析2014,,4: | 1 |
| 14 | Radiology–Pathology Conference: sclerosing hemangioma of the lung显示文摘 | Jeremy Neuman Alex Rosioreanu Allan Schuss George Turi Elizabeth Yung Terence K. Trow Lewis Williams Douglas S. Katz | 2006 | Clinical Imaging2006,,6: | 1 |
| 15 | 双黄连口服液成分的快速检定 UNIFI整体解决方案应用于中药质量控制显示文摘本实验采用UNIFI天然产物整体解决方案中二元比较的工作流程.对两个厂家的双黄连口服液化学组分的异同进行检定,以便了解不同厂家产品的成分差异,有助于厂家监控不同批次间产品的质量稳定性。也为所有类似情况的二元比较工作提供了简单、有效的解决方案。 | 乔立瑞 谭晓杰 Rob Lewis Alex Hooper James Morphet Kate Yu | 2014 | 实验与分析2014,,3: | 0 |
| 16 | Think global,cube local:an Earth Observation Data Cube’s contribution to the Digital Earth vision显示文摘The technological landscape for managing big Earth observation(EO)data ranges from global solutions on large cloud infrastructures with web-based access to self-hosted implementations.EO data cubes are a leading technology for facilitating big EO data analysis and can be deployed on different spatial scales:local,national,regional,or global.Several EO data cubes with a geographic focus(“local EO data cubes”)have been implemented.However,their alignment with the Digital Earth(DE)vision and the benefits and trade-offs in creating and maintaining them ought to be further examined.We investigate local EO data cubes from five perspectives(science,business and industry,government and policy,education,communities and citizens)and illustrate four examples covering three continents at different geographic scales(Swiss Data Cube,semantic EO data cube for Austria,DE Africa,Virginia Data Cube).A local EO data cube can benefit many stakeholders and players but requires several technical developments.These developments include enabling local EO data cubes based on public,global,and cloud-native EO data streaming and interoperability between local EO data cubes.We argue that blurring the dichotomy between global and local aligns with the DE vision to access the world’s knowledge and explore information about the planet. | Martin Sudmanns Hannah Augustin Brian Killough Gregory Giuliani Dirk Tiede Alex Leith Fang Yuan Adam Lewis | 2023 | Big Earth Data2023,7,3: | 0 |
| 17 | 有效的能量监测与定位以实现可持续改进显示文摘TSP Trostre是英国克鲁斯/塔塔公司第一个(目前唯一)获得碳信托标准认证的钢厂,以认可其在减少碳足迹方面所做出的承诺。碳信托是英国政府成立的独立的非营利性组织,旨在支持和监控CO2减排,并对那些在减少CO2足迹方面取得显著成效的企业颁予碳信托标准认证。获得认证的企业可以宣传其减碳成果,并使用碳信托标记,这类似于其产品和客户文件夹上的最佳实践'风筝标志'。这项认证措施的实行,使得TSP Trostre厂自2006年以来实现了每吨产品连续年减排2.5%CO2的业绩,连同塔塔其他企业在内,力争于2013/2014年达到减排15%CO2的目标,这意味着企业目前有两个'活'目标。TSP Trostre厂每年为包装厂生产40万t钢卷,其用于公共设施的费用每年约为2 100万英镑(2010年),占克鲁斯英国厂能源投资中煤气投资的第4位、电力投资的第5位。这项成就的基础主要在于对其能量使用采用持续改进的'监测和定位'策略。利用有限的资金以及20世纪90年代中期残存的一些硬件/软件,TSP Trostre决定至21世纪中期开发出一个综合的且优于'特殊节能设备'的监测与计量系统。基于这个系统,安装无数计量表并收集来自32个欧洲数据采集点的数据,同时反馈到与内网服务器相连的中心数据库。 | Darryl Lewis CEng Alex Chu 王楠 | 2014 | 世界钢铁2014,0,6: | 0 |
| 18 | 绿茶提取物中化学成分的鉴定——采用UNIFI天然产物整体解决方案鉴定绿茶成分显示文摘本文使用超高效液相色谱(UPLC)、四级杆飞行时间质谱以及中药数据库为基础的UNIFI天然产物解决方案相结合分析绿茶中的化学成分。该法将实验采集、数据处理与中药数据库的导入有机结合起来,使得复杂中药体系中化学组分的定性工作变得简单、有效、程序化.大大提高工作效率,降低了对操作人员技术背景的要求。 | 乔立瑞 Rob Lewis Alex Hooper James Morphet 谭晓杰 Kate Yu | 2014 | 实验与分析2014,,5: | 0 |
| 19 | Rapid,high-resolution detection of environmental change over continental scales from satellite data–the Earth Observation Data Cube显示文摘The effort and cost required to convert satellite Earth Observation(EO)data into meaningful geophysical variables has prevented the systematic analysis of all available observations.To overcome these problems,we utilise an integrated High Performance Computing and Data environment to rapidly process,restructure and analyse the Australian Landsat data archive.In this approach,the EO data are assigned to a common grid framework that spans the full geospatial and temporal extent of the observations–the EO Data Cube.This approach is pixel-based and incorporates geometric and spectral calibration and quality assurance of each Earth surface reflectance measurement.We demonstrate the utility of the approach with rapid time-series mapping of surface water across the entire Australian continent using 27 years of continuous,25 m resolution observations.Our preliminary analysis of the Landsat archive shows how the EO Data Cube can effectively liberate high-resolution EO data from their complex sensor-specific data structures and revolutionise our ability to measure environmental change. | Adam Lewis Leo Lymburner Matthew B.J.Purss Brendan Brooke Ben Evans Alex Ip Arnold G.Dekker James R.Irons Stuart Minchin Norman Mueller Simon Oliver Dale Roberts Barbara Ryan Medhavy Thankappan Rob Woodcock Lesley Wyborn | 2016 | International Journal of Digital Earth2016,9,1: | 0 |