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| 1 | The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline显示文摘 | Gaspar LE Mehta MP Patchell RA Burri SH Robinson PD Morris RE Ammirati M Andrews DW Asher AL Cobbs CS Kondziolka D Linskey ME Loeffler JS McDermott M Mikkelsen T Olson JJ Paleologos NA Ryken TC Kalkanis SN. | 2010 | 中国神经肿瘤杂志2010，8，1： | 98 |
| 2 | Intratumoral dendritic cell vaccin ation elicits potent tumoricidal im munity against malignant glioma in rats显示文摘Dendritic cells(DC)are attractive candidates for innovative cancer immunotherapy by virtu e of their ability to function as powe rful antigen presenting cells and elicit potent antitumor cytotoxic immune r esponses.With the aim of generating antitumor immunity,the authors sought to enhance in vivo tum or antigen presentation by using an i ntratumoral DC vaccination strateg y in the setting of partially irradiated intracranial brain tumo rs.Fisher rats,implanted with 9L gliomas in the right corpus striatum,w ere treated with freshly cultured,unpulsed syngeneic DC inoculated directly into the tumor bed.Intracranially inoculated DCs were found to drain to ipsilateral deep cervical lymph nodes.This was a ssociated with increased local and s ystemic antitumor cytoxicity,as evidenced by robust infiltration of treated tumors with CD4and CD8T ce lls as well as by increased IFN-gamma protein and message levels in in vitr o restimulated splenic lymphocytes.DC therapy resulted in prolonged survival and immunity to s ubsequent intracranial tumor re-ch allenge.These results demonstrate the viability of intratumoral DC vaccination as an effectiv e therapeutic strategy for intracra nial glioma. | Ehtesham M Kabos P Gutierrez MA Samoto K Black KL Yu JS | 2003 | 癌症2003，22，7： | 8 |
| 3 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 4 | Numerical Modeling on Suspended Sediment Transportation in the Hangzhou Bay显示文摘In this paper the characteristics of tidal flow and seasonal variation of seidment content in theHangzhou Bay and their affecting factors are studied.Field investigations and data analysis indicate thatthe sediment movement is mainly influenced by the Yangtze estuary and the sediment of the Yangtze estua-ry is induced by wind wave and tidal flow.Owing to the variation of dynamic conditions,the instanta-neous sediment content is controlled by tidal flow,wind wave,depth of water and tidal range synthetically.A sediment content relationship formula is established with related factors.A non-equilibrium2-dimensional numerical model of suspended sediment transportation is set up,and the finite element meth-od is applied.The computation results of the model is in accordance with field data. | Zhang, JS Lu, PD Xu, M | 1998 | China Ocean Engineering1998，13，1： | 7 |
| 5 | 儿童期肥胖、成年期肥胖和心血管风险因子显示文摘过去30年,儿童超重或肥胖的发生率明显增加[1]。儿童期肥胖是死亡率增加的预测因子,这主要是由于儿童期肥胖可导致心血管疾病发生率增加。相关的预测研究提示"肥胖流行症"可能改变目前心血管疾病死亡率下降的趋势,使现今儿童的寿命缩短。 | Juonala M Magnussen CG Berenson GS Venn A Burns TL Sabin MA Srinivasan SR Daniels SR Davis PH Chen W Sun C Cheung M Viikari JS Dwyer T Raitakari OT 叶鹏 | 2012 | 中华高血压杂志2012，20，1： | 6 |
| 6 | 手部烧伤后术中止血和包扎对其功能恢复的影响显示文摘 | 吕国忠 朱宇刚 顾在秋 Fish JS Beveridge M | 2004 | 中华烧伤杂志2004，20，5： | 4 |
| 7 | Small interfering RNA inhibits SARS-CoV nucleocapsid gene expression in cultured cells and mouse muscles显示文摘 | Zhao P Qin ZL Ke JS Lu Y Liu M Pan W Zhao LJ Cao J Qi ZT | 2005 | 第二军医大学学报2005，26，10： | 4 |
| 8 | Long-term results of laparoscopic extended surgery in advanced gastric cancer:A series of 101 patients显示文摘 | Azagra JS Ibanez Aguirre JF Goergen M | | 0，，68： | 3 |
| 9 | 咬合与脑功能相关性研究进展显示文摘本文综述了咬合对全身健康尤其是脑功能的影响.从1999 ~ 2011年英文在线文献和图书馆的相关文献中,选择可用的19篇文献分为咀嚼和舌运动,紧咬牙和磨牙症,咬合板和咬合干扰,修复重建,疼痛和刺激等5类.总结了咀嚼口香糖、叩齿和紧咬牙运动等口颌面区运动与大脑感觉和运动皮层激活的相关性.感觉运动皮层的激活也会受到咬合干扰装置、咬合板和种植修复体的影响.大脑激活区的改变可能依赖于口颌面区运动的强度.因此,咀嚼和其它运动刺激能激活大脑皮层,从而可能有助于防止脑功能的退化,然而,这些发现必须由更多研究所证实. | Ohkubo C(综述) Morokuma M(综述) Yoneyama Y(综述) Matsuda R(综述) Lee JS(综述) 姜华(审校) | 2013 | 实用口腔医学杂志2013，29，6： | 3 |
| 10 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 11 | Severin classification system for evaluation of the results of operative treatment of congenital dislocation of the hip显示文摘 | Ward WT Vogt M Grudziak JS | 1997 | J Bone Joint Surg1997，79，5： | 2 |
| 12 | Factors that impact health-related quality of life in adults with celiac disease:A multicenter study显示文摘AIM: To evaluate the factors involved in the impairment of health-related quality of life (HRQOL) in patients with celiac disease.METHODS: A multicenter, cross-sectional prospective study was performed in patients with celiac disease who completed two HRQOL questionnaires: the gastrointestinal quality of life index (GIQLI) and the EuroQol-5D (EQ).RESULTS: Three hundred and forty patients (163 controlled with a gluten-free diet, and 177 newly diagnosed with a normal diet) were included. The GIQLI score was significantly better in patients on a gluten-free diet (GFD) than in non-treated patients on their usual diet, both in terms of the overall score (3.3 vs 2.7, respectively; P < 0.001), as well as on the individual questionnaire dimensions. Both the preference value of the EQ as the visual analogue scale were significantly better in treated than in non-treated patients (0.93 vs 0.72 P < 0.001 and 80 vs 70 P < 0.001, respectively). Variables significantly associated with a worse HRQOL score were female gender, failure to adhere to a GFD, and symptomatic status.CONCLUSION: In untreated celiac disease, the most important factors that influence patient perception of health are the presence of symptoms and a normal diet. HRQOL improves to levels similar to those described in the general population in celiac disease patients well controlled with a GFD. | F Casellas L Rodrigo J López Vivancos S Riestra C Pantiga JS Baudet F Junquera V Puig Diví C Abadia M Papo J Gelabert JR Malagelada | 2008 | World Journal of Gastroenterology2008，14，1： | 2 |
| 13 | Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides显示文摘 | Zhong M Munzer JS | 2001 | Biochem J2001，353，3： | 1 |
| 14 | The origins of genome complexity显示文摘 | Lynch M Conery JS | 2003 | Science2003，302，5649： | 1 |
| 15 | Molecular insights into the lineage-specific determination of odontoblasts:The role of Cbfα1显示文摘 | Gaikwad JS Hoffmann M Cavender A | 2001 | Adv Dent Res2001，15，： | 1 |
| 16 | Structure characterization of normal and mutant human steroid 17α-hydroxylase gene:molecular basis of one example of combined 17α-hydroxylase and 17,20-lyase deficiency显示文摘 | Kagimoto M Winter JS Kagimoto K | 1988 | Mol Endocrinol1988，2，6： | 1 |
| 17 | Mechanism of mutagenesis by O6-methylguanine显示文摘 | Eadie JS Conrad M Toorchen D | 1984 | Nature1984，308，5955： | 1 |
| 18 | The effect of uvulopalato-pharyngoplasty on the nasality of voice显示文摘 | Greene JS Zipfel TE Harlor M | 2004 | J Voice2004，18，3： | 1 |
| 19 | ICF core sets:how to specify impairment and function in systemic Lupus erythematosus显示文摘 | Aringer M Stamm TA Pisetsky DS Yarboro CH Cieza A Smolen JS | 2006 | Lupus2006，15，： | 1 |
| 20 | Inflammation, obesity, stress and coronary heart disease :is interleukin-6 the link? 显示文摘 | Yudkin JS Kumari M Humphries SE | 2000 | Atherosclerosis2000，148，2： | 1 |
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