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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Association of Helicobacter pylori infection and giardiasis: Results from a study of surrogate markers for fecal exposure among children显示文摘AIM: To investigate whether Helicobacter pylori (H pykori)infection is associated with hepatitis A virus (HAV) infection, presence of enteroparasites, and other surrogates of fecal exposure.METHODS: We conducted a cross-sectional study in 121 children consecutively admitted at a pediatric hospital inSalvador, Brazil.H pylori and HAV infection were identified by the presence of serum antibodies. Stool specimens were examined for the presence of ova and parasites. A structured questionnaire inquiring about sanitary conditions and life style was applied to each subject. RESULTS: Fifty-one of the 121 children (42.1%) werefound to be seropositive for H pylori, and 45 (37.2%) for HAV. The seroprevalence ofHpyloriand HAV both increased significantly with age. Cross-tabulation of data showed that 26 (21.5%) were seropositive and 51 (42.1%) were negative for bothHpyloriand HAV antibodies (χ2 = 7.18,OR = 2.8, CI 1.30-5.97). The age adjusted OR for an HAV-infected child being H pylori positive was 2.3 (CI1.02-5.03). The agreement between H pylori and HAVseropositivity was fair (κ = 0.24). After controlling for possible confounding, the variables remaining independently associated with seropositivity to H pyloriwere age,presence of Giardia lamblia in feces (OR = 3.2, 95%CI, 1.1-9.5) and poor garbage disposal quality (OR = 2.4,95%CI, 1.1-5.1).CONCLUSION: Our data suggest that H pylori infection is associated with surrogate markers of fecal exposure. Thus, we conclude that the fecal-oral route is relevant in the transmission of HP among children in an urban setting of a developing country. The association observed between G. lamblia and H pylori infection may have several explanations. Further studies to investigate this relationship are warranted. | Edson Duarte Moreira Jr Victor Bastos Nassri Rafaela Sousa Santos Junísia Ferraz Matos Wilson Andrade de Carvalho Célia Stolve Silvani Círia Santana e Sant'Ana | 2005 | World Journal of Gastroenterology2005，11，18： | 3 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Incidence of Important Hemobilia Following Transhepatic Biliary Drainage: Left-Sided Versus Right-Sided Approaches显示文摘 | G. M. Rivera-Sanfeliz O. S. A. Assar J. M. LaBerge M. W. Wilson R. L. Gordon E. J. Ring R. K. Kerlan Jr | 2004 | CardioVascular and Interventional Radiology2004，，： | 2 |
| 5 | Guided tissue regeneration around dental implants in immediate and recent extraction sites: initial observations 显示文摘 | Wilson TG Jr | 1992 | Int J Periodontics Restorative Dent1992，12，3： | 1 |
| 6 | Development,cytokine profile and function of human interleukin 17-producing helper T cells显示文摘 | Wilson NJ Boniface K Chan JR | | 0，，09： | 1 |
| 7 | Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain显示文摘 | Wilson HD Wilson JR Fuchs PN | | 0，，1： | 1 |
| 8 | A toxicity index of skin and wound cleansers used on in vitro fibroblasts and keratinocytes 显示文摘 | Wilson JR Mills JG Prather ID | 2005 | Adv Skin Wound Care2005，18，7： | 1 |
| 9 | Hospital ownership and technical inefficiency 显示文摘 | Burgess Jr J F Wilson P W | 1996 | Management Science1996，42，1： | 1 |
| 10 | Enhancement of imipramine antidepressant activity by thyroid hormone显示文摘 | Prange AJ Jr Wilson IC Rabon AM | 1969 | Am J Psychiatry1969，126，4： | 1 |
| 11 | Joining of PM materials-Sinter-brazing automotive powertrain components显示文摘 | WILSON C HAMILL Jr J A | 2001 | International Journal of Powder Metallurgy2001，37，7： | 1 |
| 12 | Incidence and risk factors for glaucoma after pediatric cataract surgery with and without intraocular lens implantation 显示文摘 | Trivedi R H Wilson M E Jr Golub R L | 2006 | J AAPOS2006，10，： | 1 |
| 13 | Treatment of traumatic spondylolisthesis of the axis with nonrigid immobilization:a review of 64 cases显示文摘 | Coric D Wilson JA Kelly DL Jr | | 0，，： | 1 |
| 14 | LASIK vs LASEK vs PRK;advantages andindications显示文摘 | Ambrdsio R Jr Wilson S | 2003 | Semin Ophthalmol2003，18，1： | 1 |
| 15 | Multimodality imaging of a dissec- ting intramyocardial hematoma extending into the left atrial wall fillowing myo- cardial infarction 显示文摘 | Wilson JR Marshall RJ Shanbhag SM | 2012 | Citxulation2012，126，23： | 1 |
| 16 | LASIK-associated dry eye and neurotrophic epitheliopathy:pathophysiology and strategies for prevention and treatment显示文摘 | Ambrósio R Jr Tervo T Wilson SE | 2008 | J Refract Surg2008，24，4： | 1 |
| 17 | Secondary intraocular lens implantation for pediatric aphakia 显示文摘 | Trivedi RH Wilson ME Jr Facciani J | 2005 | J AAPOS2005，9，4： | 1 |
| 18 | Effect of seed moisturization and fungicide treatment on final stand of low vigor shrunken-2 sweet corn inbreds显示文摘 | Wilson D O Jr Mohan S K | 1992 | Journal of Production Agriculture1992，5，： | 1 |
| 19 | Regulation of interferon- gamma during innate and adaptive immune responses 显示文摘 | Schoenborn JR Wilson CB | 2007 | Adv Immunol2007，96，： | 1 |
| 20 | Coffee consumption and prostate cancer risk and progression in the Health Professionals Follow up Study 显示文摘 | Wilson KM Kasperzyk JL Rider JR | 2011 | J Natl Cancer Inst2011，103，1： | 1 |
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