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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | Long-term results of laparoscopic extended surgery in advanced gastric cancer:A series of 101 patients显示文摘 | Azagra JS Ibanez Aguirre JF Goergen M | | 0，，68： | 3 |
| 3 | Laparoscopic liver resection of benign liver tumors显示文摘 | B. Descottes D. Glineur F. Lachachi D. Valleix J. Paineau A. Hamy M. Morino H. Bismuth D. Castaing E. Savier P. Honore O. Detry M. Legrand J.S. Azagra M. Goergen M. Ceuterick J. Marescaux D. Mutter B. Hemptinne R. Troisi J. Weerts B. Dallemagne C. Jehaes | 2003 | Surgical Endoscopy2003，，4： | 2 |
| 4 | haparoscopic liver resectiOn for malignant liver tumors:preliminary results of a multicenter European study显示文摘 | Gigot JF Glineur D Santiago Azagra J | 2002 | Ann Surg2002，236，1： | 1 |
| 5 | Proximal calculus on Riemannian Manifolds 显示文摘 | Azagra D Ferrera J | 2005 | Mediterranean Jorunal of Mathematics2005，2，： | 1 |
| 6 | Laparoscopic liver resection for malignant liver tumors:preliminary results of amulti center European study显示文摘 | Gigot JF Glineur D Santiago Azagra J | 2002 | Ann Surg2002，236，1： | 1 |
| 7 | Laparoscopic anatomical (hepatic)left lateral segmentectomy-technical aspects显示文摘 | Azagra JS Goergen M Gilbart E | 1996 | Surg Endose1996，10，7： | 1 |
| 8 | Laparoscopic liver resection for malignant liver tumors: preliminary results of a multicenter European study 显示文摘 | Gigot JF Glineur D Santiago Azagra J | 2002 | Ann Surg2002，236，1： | 1 |
| 9 | Pediatric acute lung injury epidemiology and natural history study:incidence and outcome of the acute respiratory distress syndrome in children显示文摘 | López-Fernández Y Azagra AM de 1a Oliva P | | 0，，12： | 1 |
| 10 | Usefulness of FRAX tool for the management of oste- oporosis in the Spanish female population 显示文摘 | Azagra Ledesma R Prieto-Alhambra D Encabo Duro G | 2011 | Med Clin2011，136，： | 1 |
| 11 | Laparoscopic pancreatic resecton:results of a nmlticenter European study of 127 patients显示文摘 | Mabrut JY Femandez-Cruz L Azagra JS | | 0，，： | 1 |
| 12 | Pediatric ARDS:effect of supine-prone postural changes on oxygenation显示文摘 | asado-Flores J Martinez de Azagra A Ruiz-Lopez MJ | 2002 | Intensive Care Med2002，28，12： | 1 |
| 13 | FRAX?tool,the WHO algorithm to predict osteoporotic fractures:the first analysis of its discriminative and predictive ability in the Spanish FRIDEX cohort显示文摘 | Azagra R Roca G Encabo G | 2012 | BMC Musculoskeletal Disorders2012，13，6： | 1 |
| 14 | Laparoscopic liver resection for malignant liver tumors:preliminary results of a multicenter European study显示文摘 | Gigot JF Glineur D Santiago Azagra J | 2002 | Ann Surg2002，36，1： | 1 |
| 15 | Minimally invasive surgery for gastric cancer显示文摘 | Azagra JS Goergen M De Simone P | 1999 | Surg Endosc1999，13，4： | 1 |
| 16 | Laparoscopie liver resection for malignant Liver tumors : preliminary results of a multicenter European study显示文摘 | Gigot JF Glineur D Santiago Azagra J | 2002 | Ann Surg2002，236，1： | 1 |
| 17 | Laparoscopic Liver Resection for Malignant Liver Tumors: Preliminary Results of a Multicenter European Study显示文摘 | Jean-Fran?ois Gigot David Glineur Juan Santiago Azagra Martine Goergen Marc Ceuterick Mario Morino José Etienne Jacques Marescaux Didier Mutter Ludo van Krunckelsven Bernard Descottes Dominique Valleix Fran?ois Lachachi Claude Bertrand Baudouin Mansvelt G | 2002 | Annals of Surgery2002，，1： | 1 |
| 18 | Laparoscopic anatomical(hepatic)left lateral segmentectomy-technical aspects显示文摘 | Azagra JS Goergen M Gilbart E | 1996 | Surg Endosc1996，10，7： | 1 |
| 19 | Long-term results of laparoscopic extended surgery in advanced gastric cancer: a series of 101 patients显示文摘 | Azagra JS Ibafiez-Aguirre JF Goergen M | 2006 | Hepatogastroenterology2006，53，68： | 1 |
| 20 | Minimally invasive surgery for gastric cancer显示文摘 | Azagra JS Goergen M De Simone P | 1999 | Surg Endosc1999，13，： | 1 |
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