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| 1 | Porous LiF layer fabricated by a facile chemical method toward dendrite-free lithium metal anode显示文摘Lithium metal is supposed to be critical material for constructing next-generation batteries due to extremely high capacity and ultralow redox potential. However, the perplexing issue of lithium dendrite growth impedes the commercial application. The initial nucleation and low Li ions diffusion rate in the electrolyte/electrode interface dominate the deposition behavior. Therefore, a uniform and flexible interface is urgently needed. Here, a facile method is proposed to prepare a thin and porous LiF-rich layer (TPL) by the in-situ reaction of small amount of ammonium hydrogen difluoride (NH4HF2) and Li metal. The deposition morphology on Li metal anode with LiF layer is significantly flat and homogeneous owning to low lateral diffusion barrier on LiF crystals and the porous structure of TPL film. Additionally, the symmetrical cells made with such TPL Li anodes show significantly stable cycling over 100 cycles at high current density of 6 mA/cm^2. The TPL Li|LiFePO4 full cells keep over 99% capacity retention after 100 cycles at 2.0 C. This approach serves as a facile and controllable way of adjusting the protective layer on Li metal. | Yanxia Yuan Feng Wu Guanghai Chen Ying Bai Chuan Wu | 2019 | Journal of Energy Chemistry2019，28，10： | 14 |
| 2 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020，30，9： | 7 |
| 3 | Preparation and characterization of amorphous silica nanowires from natural chrysotile显示文摘 | Kun Liu Qiming Feng Yanxia Yang Guofan Zhang Leming Ou Yiping Lu | 2007 | Journal of Non-Crystalline Solids2007，，16： | 2 |
| 4 | Current management of chemotherapy-induced neutropenia in adults:key points and new challenges显示文摘Chemotherapy-induced neutropenia(CIN)is a potentially fatal and common complication in myelosuppressive chemotherapy.The timing and grade of CIN may play prognostic and predictive roles in cancer therapy.CIN is associated with older age,poor functional and nutritional status,the presence of significant comorbidities,the type of cancer,previous chemotherapy cycles,the stage of the disease,specific chemotherapy regimens,and combined therapies.There are many key points and new challenges in the management of CIN in adults including:(1)Genetic risk factors to evaluate the patient’s risk for CIN remain unclear.However,these risk factors urgently need to be identified.(2)Febrile neutropenia(FN)remains one of the most common reasons for oncological emergency.No consensus nomogram for FN risk assessment has been established.(3)Different assessment tools[e.g.,Multinational Association for Supportive Care in Cancer(MASCC),the Clinical Index of Stable Febrile Neutropenia(CISNE)score model,and other tools]have been suggested to help stratify the risk of complications in patients with FN.However,current tools have limitations.The CISNE score model is useful to support decision-making,especially for patients with stable FN.(4)There are still some challenges,including the benefits of granulocyte colony stimulating factor treatment and the optimal antibiotic regimen in emergency management of FN.In view of the current reports,our group discusses the key points,new challenges,and management of CIN. | Committee of Neoplastic Supportive-Care(CONS),China Anti-Cancer Association Committee of Clinical Chemotherapy,China Anti-Cancer Association Yi Ba Yuankai Shi Wenqi Jiang Jifeng Feng Ying Cheng Li Xiao Qingyuan Zhang Wensheng Qiu Binghe Xu Ruihua Xu Bo Shen Zhiguo Luo Xiaodong Xie Jianhua Chang Mengzhao Wang Yufu Li Yuerong Shuang Zuoxing Niu Bo Liu Jun Zhang Li Zhang Herui Yao Conghua Xie Huiqiang Huang Wangjun Liao Gongyan Chen Xiaotian Zhang Hanxiang An Yanhong Deng Ping Gong Jianping Xiong Qinghua Yao Xin An Cheng Chen Yanxia Shi Jialei Wang Xiaohua Wang Zhiqiang Wang Puyuan Xing Sheng Yang Chenfei Zhou | 2020 | Cancer Biology & Medicine2020，17，4： | 2 |
| 5 | Long-term effects of high lipid and high energy diet on serum lipid, brain fatty acid composition, and memory and learning ability in mice显示文摘 | Huanling Yu Yanxia Bi Weiwei Ma Lingling He Linhong Yuan Jinfang Feng Rong Xiao | 2009 | International Journal of Developmental Neuroscience2009，，3： | 1 |
| 6 | Thermal properties optimization of envelope in energy-saving renovation of existing public buildings显示文摘 | Jianen Huang Henglin Lv Tao Gao Wei Feng Yanxia Chen Tai Zhou | 2014 | Energy & Buildings2014，，： | 1 |
| 7 | Effects of composting process on the dissipation of extractable sulfonamides in swine manure显示文摘 | Bei Liu Yanxia Li Xuelian Zhang Chenghong Feng Min Gao Qiu Shen | 2014 | Bioresource Technology2014，，： | 1 |
| 8 | Highly effective visible-photocatalytic hydrogen evolution and simultaneous organic pollutant degradation over an urchin-like oxygen-doped MoS_(2)/ZnIn_(2)S_(4)composite显示文摘Achieving hydrogen production and simultaneous decomposition of organic pollutants through dual-functional photocatalytic reactions has received increasing attention due to the environmentally friendly and cost-effective characteristics of this approach.In this work,an urchin-like oxygen-doped MoS_(2)/ZnIn_(2)S_(4)(OMS/ZIS)composite was fabricated for the first time using a simple solvothermal method.The unique microstructure with abundant active sites and fast charge transfer channels further shortened the charge migration distance and compressed carrier recombination.The obtained composite exhibited an efficient H2 evolution reaction rate of 12.8 mmol/g/h under visible light,which was nearly times higher than pristine ZnIn_(2)S_(4),and the apparent quantum efficiency was 14.9%(420 nm).The results of the simultaneous photocatalytic H2 evolution and organic pollutant decomposition test were satisfactory,resulting in decomposition efficiencies of resorcinol,tetracycline,and bisphenol A that reached 41.5%,63.5%,and 53.0%after 4 h,respectively,and the highest H2 evolution rate was 672.7 umol/g/h for bisphenol A.Furthermore,natural organic matter(NOM)abundantly found in actual water was adopted as an electron donor for H production under simulated sunlight irradiation,indicating the promising practicability of simultaneous hydrogen evolution and NOM decomposition.Moreover,the mechanisms of the dual-purpose photocatalytic reactions,as well as the synergistic effect between the molecular structures of the organic pollutants and the corresponding adsorption behavior on the photocatalyst surface were illustrated in detail.These obtained results may serve as an inspiration for the rational design of highly efficient,dual-functional photocatalysts in the future. | Tao Yan Qianqian Yang Rui Feng Xiang Ren Yanxia Zhao Meng Sun Liangguo Yan Qin Wei | 2022 | Frontiers of Environmental Science & Engineering2022，16，10： | 1 |
| 9 | Tobacco bacterial wilt can be biologically controlled by the application of antagonistic strains in combination with organic fertilizer显示文摘 | Yanxia Liu Junxiong Shi Yonggang Feng Xingming Yang Xiang Li Qirong Shen | 2013 | Biology and Fertility of Soils2013，，4： | 1 |
| 10 | Preparation and characterization of amorphous silica nanowires from natural chrysotile显示文摘 | Kun Liu Qiming Feng Yanxia Yang Guofan Zhang Leming Ou Yiping Lu | 2007 | Journal of Non-Crystalline Solids2007，，16： | 1 |
| 11 | Characteristics of secondary droplets produced by the impact of drops onto a smooth surface显示文摘This work investigates the splashing behaviors of droplets impacting on solid surfaces and mainly focuses on the characteristics of secondary droplets.According to the experimental results,two different splashing patterns,corona splash and levitating-lamella breakup,are observed.A new breakup mode,named rimsegmenting,is found during the levitating-lamella breakup.In particular,the detailed information of the splashing secondary droplets,including the size,velocity,angle,and total volume of the splashing secondary droplets is obtained from the experimental data.The size distribution of the splashing secondary droplets obeys the gamma distribution function.The average diameter and splashing angle of the secondary droplets are mainly related to the Reynolds number Re,and can be expressed as functions of Re.High impact velocity and liquid viscosity will result in a wider size distribution range of splashing secondary droplets.We also put forward an empirical model to predict the total splashing volume,which is consistent with the experimental data both in this work and previous studies.This work is believed to provide insights on the prediction of the characteristics of splashing secondary droplets. | Haixiang Zhang Ye Gao Xiwen Zhang Xian Yi Yanxia Du Feng He Zheyan Jin Pengfei Hao | 2021 | Advances in Aerodynamics2021，3，1： | 1 |
| 12 | Quantitative detemination of zinc in milkvetch by anodic stripping voltammerty with bismuth film electrodes显示文摘 | Guo Ziying Feng Feng Hou Yanxia | 2005 | Talanta2005，65，： | 1 |
| 13 | A PRIORI AND A POSTERIORI ERROR ESTIMATES OF A WEAKLY OVER-PENALIZED INTERIOR PENALTY METHOD FOR NON-SELF-ADJOINT AND INDEFINITE PROBLEMS显示文摘在这份报纸,我们为 non-self-adjoint 和不定的问题学习一个弱过去惩罚的内部惩罚方法。一最佳在精力标准的 priori 错误估计被导出。另外,我们介绍一基于剩余一个 posteriori 错误评估者,它被证明在精力标准可靠、有效。一些数字睾丸被介绍验证我们的理论分析。[从作者抽象] | Yuping Zeng Jinru Chen Feng Wang Yanxia Meng | 2014 | Journal of Computational Mathematics2014，32，3： | 1 |
| 14 | MST4 kinase regulates immune thrombocytopenia by phosphorylating STAT1-mediated M1 polarization of macrophages显示文摘Primary immune thrombocytopenia(ITP)is an autoimmune hemorrhagic disorder in which macrophages play a critical role.Mammalian sterile-20-like kinase 4(MST4),a member of the germinal-center kinase STE20 family,has been demonstrated to be a regulator of inflammation.Whether MST4 participates in the macrophage-dependent inflammation of ITP remains elusive.The expression and function of MST4 in macrophages of ITP patients and THP-1 cells,and of a macrophage-specific Mst4−/−(Mst4ΔM/ΔM)ITP mouse model were determined.Macrophage phagocytic assays,RNA sequencing(RNA-seq)analysis,immunofluorescence analysis,coimmunoprecipitation(co-IP),mass spectrometry(MS),bioinformatics analysis,and phosphoproteomics analysis were performed to reveal the underlying mechanisms.The expression levels of the MST4 gene were elevated in the expanded M1-like macrophages of ITP patients,and this elevated expression of MST4 was restored to basal levels in patients with remission after high-dose dexamethasone treatment.The expression of the MST4 gene was significantly elevated in THP-1-derived M1 macrophages.Silencing of MST4 decreased the expression of M1 macrophage markers and cytokines,and impaired phagocytosis,which could be increased by overexpression of MST4.In a passive ITP mouse model,macrophage-specific depletion of Mst4 reduced the numbers of M1 macrophages in the spleen and peritoneal lavage fluid,attenuated the expression of M1 cytokines,and promoted the predominance of FcγRIIb in splenic macrophages,which resulted in amelioration of thrombocytopenia.Downregulation of MST4 directly inhibited STAT1 phosphorylation,which is essential for M1 polarization of macrophages.Our study elucidates a critical role for MST4 kinase in the pathology of ITP and identifies MST4 kinase as a potential therapeutic target for refractory ITP. | Jingjing Cao Lili Ji Yanxia Zhan Xia Shao Pengcheng Xu Boting Wu Pu Chen Luya Cheng Xibing Zhuang Yang Ou Fanli Hua Lihua Sun Feng Li Hao Chen Zhaocai Zhou Yunfeng Cheng | 2023 | Cellular & Molecular Immunology2023，20，12： | 0 |
| 15 | Compressive Behavior of Wood-based 2-D Lattice Structure under Multivariable Analysis显示文摘In order to optimize the out-of-plane compression performance of the wood structure,wood-based 2-D lattice structures were designed and manufactured with oriented strand board as the panel and birch round stick as the core by using a simple insert-glue method.In this experiment,the different thicknesses of the upper and lower panels,the different shavings arrangement directions of the upper and lower panels and the different configurations of the specimens were used to analyze the compression performance of the specimens under multivariable conditions.Through the combination of experimental test and theoretical analysis,we analyzed and compared different failure types of the structure and multiple compression parameters.The results showed that the shavings arrangement direction of the panel has a more important influence on the whole specimen than the thickness of the panel,especially the transverse shavings of the panel can withstand greater shear stress than the longitudinal shavings for a specimen. | Yanxia FENG Mengyuan WANG Shaochen HU Lili JIA Jihe CHEN Tianshi FENG Yingcheng HU | 2019 | Journal of Bioresources and Bioproducts2019，4，2： | 0 |
| 16 | Author Correction:MST4 kinase regulates immune thrombocytopenia by phosphorylating STAT1-mediated M1 polarization of macrophages显示文摘In this article,the details for Affiliation 1 were incorrectly given as‘Department of Hematology,Fudan University,Shanghai 200032,China’but should have been‘Department of Hematology,Zhongshan Hospital,Fudan University,Shanghai 200032,China’;the details for Affiliation 3 were incorrectly given as‘Department of Transfusion Medicine,Fudan University,Shanghai 200032,China’but should have been‘Department of Transfusion Medicine,Zhongshan Hospital,Fudan University,Shanghai 200032,China’;the details for Affiliation 4 were incorrectly given as‘Department of Laboratory Medicine,Fudan University,Shanghai 200032,China’but should have been‘Department of Laboratory Medicine,Zhongshan Hospital,Fudan University,Shanghai 200032,China’.The original article has been corrected. | Jingjing Cao Lili Ji Yanxia Zhan Xia Shao Pengcheng Xu Boting Wu Pu Chen Luya Cheng Xibing Zhuang Yang Ou Fanli Hua Lihua Sun Feng Li Hao Chen Zhaocai Zhou Yunfeng Cheng | 2023 | Cellular & Molecular Immunology2023，20，12： | 0 |
| 17 | Molecular regulation mechanism of oocyte maturation in beef cattle显示文摘Bovine oocytes are one of the indispensable cells in cattle reproduction and have become a research hot spot in cattle reproduction in recent years.The maturation process of oocytes is mainly regulated by enzymes,hormones,cytokines,and other molecules.The factors affecting cattle oocyte maturation have been previously studied to clarify the molecular mechanisms of cattle oocyte maturation.In this review article,phospholipid protein-3-kinase/protein kinase B,mitogen-activated protein kinase/extracellular signal-regulated kinase,Janus kinase/signal transducer and activator of transcription,epidermal growth factor receptor/extracellular signal-regulated kinase,and other signaling pathways related to oocyte maturation are discussed.In addition,the molecular mechanisms of some coding genes(JY-1,FGF-10,CDC20,etc.)and non-coding genes(miRNA,lncRNA,and circRNA)regulating oocyte maturation have been reviewed to provide new ideas for high reproductive performance molecular breeding of high-quality cattle. | BINWU BAO JINPENG WANG YANXIA LI FEN FENG ZHONGXIANG JI ZHUOMA LUORENG XINGPING WANG | 2023 | BIOCELL2023，47，7： | 0 |
| 18 | Multiparticle resonant optical sorting using a topological photonic structure显示文摘Resonance between light and object is highly desired in optical manipulation because the optical forces reach maximum values in this case. However, in traditional waveguide structures, the resonant interaction also greatly perturbs the incident field and weakens or completely destroys the manipulation on the subsequent particles. In order to avoid this dilemma, we propose to perform optical manipulation in a topological photonic structure.Owing to the topological protection, the light mode can almost keep its original form when an object is being manipulated. Therefore, resonant optical sorting can be achieved in a multiple and high throughput manner. The mechanism and results presented here pave the way for efficient on-chip optical sorting for biophysical and biochemical analysis. | Bojian Shi Yongyin Cao Tongtong Zhu Hang Li Yanxia Zhang Rui Feng Fangkui Sun Weiqiang Ding | 2022 | Photonics Research2022，10，2： | 0 |
| 19 | Ion-pair induced solvent extraction of lithium(Ⅰ)from acidic chloride solutions with tributyl phosphate显示文摘Lithium(Li)is an important energy metal in the 21st century.However,the selective recovery of Li is still a big challenge,especially from acidic solutions with multiple metal ions existence.Herein we report a new ion pair induced mechanism for selectively extracting Li^(+)from acidic chloride solutions by tributyl phosphate(TBP).It is shown that the acidity and the chloride ions in the aqueous phase have great effects on the extraction of Li^(+).The FT-IR,UV-Vis and ESI-MS experiments provide solid evidence for the formation of ion-pair complex[Li(TBP)_n(H_(2)O)_(m)]^(+)[FeCl_(4)]^(-)(n-1,2,3;m-0,1)in the organic phase,which brings about the effective and efficient extraction of Li^(+).This mechanism can overcome the Hofmeister bias and allow for the selective extraction of Li^(+) from the extremely hydrophilic chlorides.It has also been proved that the loaded Li in TBP can be effectively stripped by concentrated HCl solution with a Li/Fe separation factor>500.The understanding of the ion-pair transport mechanism is helpful for optimizing the recovery process or further advancing more efficient recovery techniques for Li from acidic liquor. | Li Cui Lijuan Wang Ming Feng Li Fang Yanxia Guo Fangqin Cheng | 2021 | Green Energy & Environment2021，6，4： | 0 |
| 20 | Comparing gene expression profiles of Kashin-Beck and Keshan diseases occurring within the same endemic areas of China显示文摘In this study, differentially expressed genes in peripheral blood from patients with Kashin-Beck disease and Keshan disease were compared to further investigate the etiology and pathogenesis of both diseases, which occur in a common endemic area of China. Twenty Kashin-Beck disease patients and 12 healthy controls, and 16 Keshan disease patients and 16 healthy controls, were grouped into four pairs. Patients and controls were selected from common endemic areas for the two diseases. Total RNA was isolated from peripheral blood mononuclear cells from all patients and controls, and gene expression profiles analyzed by oligonucleotide microarrays. Sixteen genes differentially expressed in both Kashin-Beck disease and Keshan disease (versus controls) were identified, and comprised nine genes showing synchronous and seven asynchronous expression. The Comparative Toxicogenomics Database shows that expression and biological function of these genes can be affected by multiple environmental factors, including mycotoxin and selenium content, potential environmental risk factors for the two diseases. Thus, these shared differentially expressed genes may contribute to the distinct organ lesions, caused by common environmental risk factors of Kashin-Beck disease and Keshan disease. | WANG Xi WANG Shuang HE ShuLan ZHANG Feng TAN WuHong LEI YanXia YU HanJie LI Zheng NING YuJie XIANG YouZhang GUO Xiong | 2013 | Science China(Life Sciences)2013，56，9： | 0 |
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