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| 1 | BMP-2和FGF-2对小鼠骨髓间充质干细胞向成骨细胞分化的影响显示文摘目的:观察骨形成蛋白(BMP-2)和成纤维细胞生长因子2(FGF-2)对小鼠骨髓间充质干细胞(MSCs)向成骨细胞分化的影响。方法:取3-18月雄性C57BL/6J小鼠(共50只)的骨髓细胞,分离贴壁培养后,用免疫磁珠法纯化,并鉴定为MSCs后,再进行贴壁培养24h后,分别在成骨细胞诱导培养液中加入100μg/LBMP-2和0.5nmol/LFGF-2持续诱导7、14、21d后,进行碱性磷酸酶染色、碱性磷酸酶活性检测,Vonkossa染色以及茜素红染色,并用递转录荧光定量PCR法检测向成骨细胞分化的标志性基因(Runx2/cbfa1、Alp、collagen-1、osteocalcin)的表达情况。结果:BMP-2刺激组的ALP活性以及钙化结节明显高于对照组,Runx2/cbfa1,ALP,collage-1,osteocalcin的mRNA呈高表达;FGF-2刺激组的ALP活性以及钙化结节也高于对照组,Runx2/cbfa1、Alp、collagen-1、osteocalcin的mRNA表达量也高于对照组,但不如BMP-2明显。结论:BMP-2和FGF-2在不同程度上促进体外培养的小鼠MSCs向成骨细胞方向分化。 | 张为西 陈松林 姚晓黎 卢锡林 周琛 冷雁 Xingming Shi | 2008 | 细胞与分子免疫学杂志2008,24,11: | 25 |
| 2 | A Strigolactone Biosynthesis Gene Contributed to the Green Revolution in Rice显示文摘Plant architecture is a complex agronomic trait and a major factor of crop yield,which is affected by several important hormones.Strigolactones(SLs)are identified as a new class hormoneinhibiting branching in many plant species and have been shown to be involved in various developmental processes.Genetical and chemical modulation of the SL pathway is recognized as a promising approach to modify plant architecture.However,whether and how the genes involved in the SL pathway could be utilized in breeding still remain elusive.Here,we demonstrate that a partial loss-of-function allele of the SL biosynthesis gene,HIGH TILLERING AND DWARF 1/DWARF17(HTD1/D17),which encodes CAROTENOID CLEAVAGE DIOXYGENASE 7(CCD7),increases tiller number and improves grain yield in rice.We found that the HTD1 gene had been widely utilized and co-selected with Semidwarf 1(SD1),both contributing to the improvement of plant architecture in modern rice varieties since the Green Revolution in the 1960s.Understanding how phytohormone pathway genes regulate plant architecture and how they have been utilized and selected in breeding will lay the foundation for developing the rational approaches toward improving crop yield. | Yuexing Wang Lianguang Shang Hong Yu Longjun Zeng Jiang Hu Shen Ni Yuchun Rao Sanfeng Li Jinfang Chu Xiangbing Meng Lei Wang Ping Hu Jijun Yan Shujing Kang Minghao Qu Hai Lin Tao Wang Quan Wang Xingming Hu Hongqi Chen Bing Wang Zhenyu Gao Longbiao Guo Dali Zeng Xudong Zhu Guosheng Xiong Jiayang Li Qian Qian | 2020 | Molecular Plant2020,13,6: | 23 |
| 3 | Genetic Architecture of Natural Variation in Rice Chlorophyll Content Revealed by a Genome-Wide Association Study显示文摘 | Quanxiu. Wang Weibo Xie Hongkun Xing Ju Yan Xiangzhou Meng Xinglei Li Xiangkui Fu Jiuyue Xu Xingming Lian Sibin Yu Yongzhong Xing Gongwei Wang | 2015 | Molecular Plant2015,8,6: | 20 |
| 4 | Structure, evolution and regional tectonic implications of the Queshan metamorphic core complex in eastern Jiaodong Peninsula of China显示文摘The Queshan MCC is an important example of a crustal extensional structure in the eastern Jiaodong Peninsula along the southeastern margin of the NCC in the Early Cretaceous. The MCC is a typical Cordilleran-type core complex with a three-layered structure:(1) the upper plate is constituted by the Cretaceous supradetachment basin and Paleoproterozoic basement;(2) the lower plate comprises the Neoarchean high-grade metamorphic complexes and late Mesozoic granitic intrusions; and(3) the two plates are separated by a master detachment fault. A series of late NEN-oriented brittle faults superimposed on and destructed the early MCC. Petrology, geometry, kinematics, macro- and micro-structures and quartz c-axis fabrics imply that the MCC has a progressive exhumation history from middle-lower to subsurface level(via middle-upper crustal level) under the nearly WNW-ESE regional extensional regime. We present structural and geochronological evidence to constrain the exhumation of the Queshan MCC from ca. 135 to 113 Ma. Based on the comprehensive analysis of the different patterns of extensional structures in the Jiaodong and Liaodong Peninsula, we have defined the Jiao-Liao Early Cretaceou extensional province and further divided the crustal extension of it into two stages: the first stage was the intense flow of the middle-lower crust and the second stage was the extension of the middle-upper crust. Combining the tectonic setting, the lithosphere thinning in the Jiao-Liao Early Cretaceous extensional province can be considered a typical model for the response of crust-mantle detachment faulting under regional extension in East Asia. | XIA ZengMing LIU JunLai NI JinLong ZHANG TingTing SHI XingMing WU Yun | 2016 | Science China Earth Sciences2016,59,5: | 17 |
| 5 | Hydrology and water resources variation and its response to regional climate change in Xinjiang显示文摘Based on the surface runoff, temperature and precipitation data over the last 50 years from eight representative rivers in Xinjiang, using Mann-Kendall trend and jump detection method, the paper investigated the long-term trend and jump point of time series, the surface runoff, mean annual temperature and annual precipitation. Meanwhile, the paper analyzed the relationship between runoff and temperature and precipitation, and the flood frequency and peak flow. Results showed that climate of all parts of Xinjiang conformably has experienced an increase in temperature and precipitation since the mid-1980s. Northern Xinjiang was the area that changed most significantly followed by southern and eastern Xinjiang. Affected by temperature and precipitation variation, river runoff had changed both inter-annually and intra-annually. The surface runoff of most rivers has increased significantly since the early 1990s, and some of them have even witnessed the earlier spring floods, later summer floods and increasing flood peaks. The variation characteristics were closely related with the replenishment types of rivers. Flood frequency and peak flow increased all over Xinjiang. Climate warming has had an effect on the regional hydrological cycle. | XU Changchun CHEN Yaning YANG Yuhui HAO Xingming SHEN Yongping | 2010 | Journal of Geographical Sciences2010,20,4: | 17 |
| 6 | Genome-wide Association Analyses Reveal the Genetic Basis of Stigma Exsertion in Rice显示文摘耻辱 exsertion,交配系统的米饭的一个关键决定因素,极大地在米饭贡献杂种优势的申请。尽管与耻辱 exsertion 联系的一些量的特点 loci 是印射或克隆的罚款,内在的基因建筑学仍然保持不清楚。我们用在 Oryza sativa 的 533 多样的就职描绘的 650 万 SNP 在耻辱 exsertion 和相关花的特点上执行了染色体宽的协会研究。我们识别了显著地与耻辱 exsertion 和相关特点,其三与三主要谷物尺寸基因 GS3, GW5,和 GW2 co 局部性被联系的 23 genomic loci。进一步的分析显示这三基因由控制小穗状花小穗和耻辱的尺寸和形状影响了耻辱 exsertion。GS3 和 GW5 的联合大部分定义耻辱 exsertion 和相关特点的层次。这二基因的选择在 O 的 subpopulations 之中导致了花的特点的特定的分布。sativa。低耻辱 exsertion 联合 gw5GS3 在栽培米饭变化的一半存在;因此,介绍 GW5gs3 联合进男无菌的线具有为改进混合米饭的种子生产的高潜力。 | Hao Zhou Pingbo Li WeiboXie Saddam Hussain Yibo Li Duo Xia Hu Zhao Shengyuan Sun Junxiao Chen Hong Ye Jun Hou Da Zhao Guanjun Gao Qinglu Zhang Gongwei Wang Xingming Lian Jinghua Xiao Sibin Yu Xianghua Li Yuqing He | 2017 | Molecular Plant2017,10,4: | 15 |
| 7 | Efficient Algorithm for K-Barrier Coverage Based on Integer Linear Programming显示文摘Barrier coverage of wireless sensor networks is an important issue in the detection of intruders who are attempting to cross a region of interest.However,in certain applications,barrier coverage cannot be satisfied after random deployment.In this paper,we study how mobile sensors can be efficiently relocated to achieve k-barrier coverage.In particular,two problems are studied:relocation of sensors with minimum number of mobile sensors and formation of k-barrier coverage with minimum energy cost.These two problems were formulated as 0–1 integer linear programming(ILP).The formulation is computationally intractable because of integrality and complicated constraints.Therefore,we relax the integrality and complicated constraints of the formulation and construct a special model known as RELAX-RSMN with a totally unimodular constraint coefficient matrix to solve the relaxed 0–1 ILP rapidly through linear programming.Theoretical analysis and simulation were performed to verify the effectiveness of our approach. | Yanhua Zhang Xingming Sun Baowei Wang | 2016 | China Communications2016,13,7: | 14 |
| 8 | Fingerprint Liveness Detection Based on Multi-Scale LPQ and PCA显示文摘Fingerprint authentication system is used to verify users' identification according to the characteristics of their fingerprints.However,this system has some security and privacy problems.For example,some artificial fingerprints can trick the fingerprint authentication system and access information using real users' identification.Therefore,a fingerprint liveness detection algorithm needs to be designed to prevent illegal users from accessing privacy information.In this paper,a new software-based liveness detection approach using multi-scale local phase quantity(LPQ) and principal component analysis(PCA) is proposed.The feature vectors of a fingerprint are constructed through multi-scale LPQ.PCA technology is also introduced to reduce the dimensionality of the feature vectors and gain more effective features.Finally,a training model is gained using support vector machine classifier,and the liveness of a fingerprint is detected on the basis of the training model.Experimental results demonstrate that our proposed method can detect the liveness of users' fingerprints and achieve high recognition accuracy.This study also confirms that multi-resolution analysis is a useful method for texture feature extraction during fingerprint liveness detection. | Chengsheng Yuan Xingming Sun Rui Lv | 2016 | China Communications2016,13,7: | 12 |
| 9 | Suppression of glutamate synthase genes significantly affects carbon and nitrogen metabolism in rice (Oryza sativa L.)显示文摘Rice (Oryza sativa) glutamate synthase (GOGAT,EC 1.4.1.14) enzymes have been proposed to have great potential for improving nitrogen use efficiency,but their functions in vivo and their effects on carbon and nitrogen metabolism have not been systematically explored.In this research,we analyzed transcriptional profiles of rice GOGAT genes using a genome-wide microarray database,and investigated the effects of suppression of glutamate synthase genes on carbon and nitrogen metabolism using GOGAT co-suppressed rice plants.Transcriptional profiles showed that rice GOGAT genes were expressed differently in various tissues and organs,which suggested that they have different roles in vivo.Compared with the wild-type,tiller number,total shoot dry weight,and yield of GOGAT co-suppressed plants were significantly decreased.Physiological and biochemical studies showed that the contents of nitrate,several kinds of free amino acids,chlorophyll,sugars,sugar phosphates,and pyridine nucleotides were significantly decreased in leaves of GOGAT co-suppressed plants,but the contents of free ammonium,2-oxoglutarate,and isocitrate in leaves were increased.We conclude that GOGATs play essential roles in carbon and nitrogen metabolism,and that they are indispensable for efficient nitrogen assimilation in rice. | LU YongEn LUO Feng YANG Meng LI XiangHua LIAN XingMing | 2011 | Science China(Life Sciences)2011,54,7: | 12 |
| 10 | An efficient rendering method for large vector data on large terrain models显示文摘This paper presents an efficient way to render large-scale vector maps on level-of-detail(LOD) digital elevation models(DEMs).By using the frame buffer and Voronoi diagram,we achieve a rapid simplification of large-scale vector maps while keeping their original topological relationships.With the simplified maps,we establish level-of-detail vector map models.In the detailed level,we use the stencil shadow volume approach to render the map accurately,and in the coarse level we use substitute techniques to render the map approximately yet more quickly.The method proposed in this paper is universally applicable to rendering vector maps on various LOD terrain models,and the overlaying performance is independent of the complexity of underlying terrain surfaces.By use of the view frustum culling and sub-region index techniques,the impact of complexity of vector maps is reduced,and the rendering time is restricted to a certain scope.Thereby,we can achieve seamless and rapid rendering of large-scale vector maps on LOD terrain surfaces. | YANG Ling ZHANG LiQiang KANG ZhiZhong XIAO ZhiQiang PENG JunHuan ZHANG XingMing LIU Liu | 2010 | Science China(Information Sciences)2010,53,6: | 11 |
| 11 | Xiaowei, a New Rice Germplasm for Large-Scale Indoor Research显示文摘Dear Editor,Rice (Oryza sativa)is a model monocot plant for biological studies due to its relatively small genome,rich germplasm resources,and high-efficiency transformation methods.Although significant progress has been made in rice genomics and functional genomics research (Li et al.,2018),large-scale indoor research toward better understanding of rice biology is hampered by its long growth period and extreme dependence on the natural environment for cultivation.There are some rice germplasms that have a short growth period and short plant height,such as Kitaake. | Shikai Hu Xingming Hu Jiang Hu Lianguang Shang Guojun Dong Dali Zeng Longbiao Guo Qian Qian | 2018 | Molecular Plant2018,11,11: | 10 |
| 12 | HOXC10 up-regulation promotes gastric cancer cell proliferation and metastasis through MAPK pathway显示文摘Objective: As an important regulator of embryonic morphogenesis,homeodomain-containing gene 10(HOXC10) has been found to promote progression of human cancers and its expression indicates poor survival outcome.However,very few studies are available on the role of HOXC10 in gastric carcinoma.Therefore,the aim of this study was to determine the role of HOXC10 in gastric cancer and the potential mechanism underlying its function for cancer biology.Methods: A primary gastric cancer mouse model was obtained via intra-gastric wall injection of gastric cancer cells and was used to evaluate the function of HOXC10 during gastric cancer progression in vivo.Immunohistochemistry was performed to visualize and measure HOXC10 protein expression in gastric cancer tissue.Cells were transfected with plasmids to increase the expression of HOXC10,and si RNA transfection was performed to suppress HOXC10 expression.Reverse transcription polymerase chain reaction(RT-PCR) and western blotting were utilized to measure m RNA and protein expression,respectively.Proliferation,migration,and invasion were investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay,wound healing assay,and matrigel invasion assay in vitro,respectively.Results: HOXC10 expression was significantly increased in gastric cancer tissues compared to matched normal tissues.HOXC10 up-regulation significantly increased tumor volumes in nude mice.Plasmid transfection significantly increased HOXC10 protein and m RNA expressions and effectively promoted cell proliferation.Moreover,HOXC10 up-regulation significantly promoted migration and invasion of gastric cancer cells.Mechanistic investigation showed that HOXC10 up-regulation significantly increased m RNA and protein expression of mitogen-activated protein kinase(MAPK) signaling related genes,including c-myc,c-jun and p53,while also modulating the phosphorylation of c-Jun N-terminal kinase(JNK),extracellular signal-regulated kinase(ERK) and P38 but not their total protein levels.Conclusions: This study demonstrated the tight link between HOXC10 and gastric cancer cell proliferation and metastasis via involvement of the MAPK pathway. | Chen Guo Jianing Hou Sheng Ao Xingming Deng Guoqing Lyu | 2017 | Chinese Journal of Cancer Research2017,29,6: | 10 |
| 13 | Co-suppressed glutamine synthetase2 gene modifies nitrogen metabolism and plant growth in rice显示文摘A full-length cDNA that encodes the rice chloroplastic glutamine synthetase 2 gene was isolated from a Minghui 63-normalized cDNA library; and GS2 rice transformants were obtained by an Agrobacterium tumefaciens-mediated transformation method. Transcripts of the GS2 gene were shown to accumulate at higher levels in the primary transgenic plants in the T0 generation; whereas plants in the T1 generation exhibited a co-suppressed chlorosis phenotype (yellow leaves) accompanied by decreased plant height, few tillers and decreased dry weight. The plants with yellow leaves also displayed a significant decline in GS2 messenger RNA (mRNA) transcriptional level and chlorophyll content; a decrease in total GS activities of ~50% was also found. Although there was no decrease in the concentration of total free amino acids, a change in the concentration of individual amino acids was observed. Our result also indicates a decreased metabolic level (soluble protein content and ammonium concentration) in GS2 co-suppressed plants. A correlation between chlorophyll content and GS2 mRNA expression level was also observed. The GS2 co-suppressed plants showed better performance when complemented with exogenous glutamine, indicating that the lack of an organic nitrogen pool inside the cell is the possible reason for the chlorosis phenotype of the transformants. | CAI HongMei XIAO JingHua ZHANG QiFa LIAN XingMing | 2010 | Chinese Science Bulletin2010,55,9: | 8 |
| 14 | The origin of Wx^(la) provides new insights into the improvement of grain quality in rice显示文摘Appearance and taste are important factors in rice(Oryza sativa) grain quality. Here, we investigated the taste scores and related eating-quality traits of533 diverse cultivars to assess the relationships between—and genetic basis of—rice taste and eating-quality. A genome-wide association study highlighted the Wx gene as the major factor underlying variation in taste and eating quality. Notably, a novel waxy(Wx) allele, Wx^(la), which combined two mutations from Wx^(b) and Wx^(in), exhibited a unique phenotype. Reduced GBSSI activity conferred Wx^(la) rice with both a transparent appearance and good eating quality. Haplotype analysis revealed that Wx^(la) was derived from intragenic recombination. In fact,the recombination rate at the Wx locus was estimated to be 3.34 kb/c M, which was about 75-fold higher than the genome-wide mean, indicating that intragenic recombination is a major force driving diversity at the Wx locus. Based on our results, we propose a new network for Wx evolution, noting that new Wx alleles could easily be generated by crossing genotypes with different Wx alleles. This study thus provides insights into the evolution of the Wx locus and facilitates molecular breeding for quality in rice. | Hao Zhou Duo Xia Da Zhao Yanhua Li Pingbo Li Bian Wu Guanjun Gao Qinglu Zhang Gongwei Wang Jinghua Xiao Xianghua Li Sibin Yu Xingming Lian Yuqing He | 2021 | Journal of Integrative Plant Biology2021,63,5: | 8 |
| 15 | Comparison Between the Audible Noises Generated from Single Corona Source Under DC and AC Corona Discharge显示文摘The corona-generated audible noise(AN)factor is an important consideration in the design and operation of ultrahigh voltage direct current(DC)and alternate current(AC)transmission lines.Due to the differences in discharge process and corona-generated space charges between the DC and AC corona discharge,the audible noise from DC and AC corona has different characteristics.This paper conducts a series of experiments by measuring the time-domain waveforms of the audible noise from a single corona source under DC and AC voltage.Sound pressure pulses are extracted from a correlation analysis,and then a detailed comparison of the basic characteristics of DC and AC corona-generated AN in time-domain and frequency spectrum is given.Results from this paper stand to contribute to an explanation of existing results in AN measurement and analysis from DC and AC transmission lines. | Xuebao Li Xiang Cui Tiebing Lu Donglai Wang Wenzuo Ma Xingming Bian | 2015 | CSEE Journal of Power and Energy Systems2015,1,3: | 8 |
| 16 | Variation and abrupt change of climate in Ili River Basin, Xinjiang显示文摘在这份报纸,在 7 点收集的每月的降水和温度数据从 1961 ~ 2007 在 Ili 河盆驻扎借助于简单回归分析,跑的平均数, db6 小浪功能和 Mann-Kendall 测试被分析。这研究在过去的 50 年以内在 Ili 河盆在不同时间规模期间揭示了气候变化的特征和降水和温度的突然的变化点。结果证明降水从 mid-1980s 增加了直到 2000 并且自从 2000,继续了在更小的大小增加。在学习时期上,降水在夏天和冬季月期间显著地增加了。温度在 1980 年代末极大地增加了,并且继续显示了从 2000 年的一个增加的趋势介绍。温度增加在夏天,秋天和冬季月期间是很重要的。以不同地理,温度增加在在平原和多山的区域的冬季期间是重要的;增加在在 intermontane 盆的秋天期间也是重要的。在 Ili 河盆的气候变化趋势与北方大西洋摆动和高原季风的变化趋势一致。 | SUN Huilan | 2010 | Journal of Geographical Sciences2010,20,5: | 8 |
| 17 | 小鼠骨髓间质干细胞的体外培养与多向分化潜能的鉴定显示文摘【目的】建立小鼠骨髓间质干细胞(MSC)体外培养、纯化、扩增方法,并进行体外定向诱导条件下的多向分化潜能鉴定。【方法】取3~18月雄性C57BL/6J小鼠(共48只)骨髓细胞,贴壁培养后,用免疫磁珠法纯化,观察纯化后的细胞形态,对3、10、20代的MSC进行细胞生长曲线绘制;并检测细胞在不同诱导条件下向成骨细胞、脂肪细胞、肌肉细胞的分化能力。【结果】小鼠MSC在体外可以诱导成成骨细胞、脂肪细胞、肌肉细胞。MSC连续传代培养达30代以上,细胞的形态、抗原表达无改变,并保持多向分化潜能。【结论】该方法获得的MSC具有高度增殖、多向分化潜能、生物学特性稳定的特点。 | 张为西 陈松林 姚晓黎 周琛 卢锡林 Xingming Shi | 2008 | 中山大学学报(医学科学版)2008,29,5: | 7 |
| 18 | A Mobile Localization Strategy for Wireless Sensor Network in NLOS Conditions显示文摘The problem of mobile localization for wireless sensor network has attracted considerable attention in recent years. The localization accuracy will drastically grade in non-line of sight(NLOS) conditions. In this paper, we propose a mobile localization strategy based on Kalman filter. The key technologies for the proposed method are the NLOS identification and mitigation. The proposed method does not need the prior knowledge of the NLOS error and it is independent of the physical measurement ways. Simulation results show that the proposed method owns the higher localization accuracy when compared with other methods. | Long Cheng Yan Wang Xingming Sun Nan Hu Jian Zhang | 2016 | China Communications2016,13,10: | 7 |
| 19 | Electroacupuncture Pretreatment at Neiguan (PC 6) attenuates autophagy in rats with myocardial ischemia reperfusion through the phosphatidylinositol 3-kinase-Akt-mammalian target of rapamycin pathway显示文摘OBJECTIVE: To investigate the protective efficacy of electroacupuncture(EA) pretreatment at Neiguan(PC6) on myocardial ischemia-reperfusion(I/R) in rats.METHODS: Fifty rats were randomly divided into five groups(n = 10): sham operation group, model group(underwent in vivo myocardial I/R), EA pretreatment group [EA at Neiguan(PC 6) 1 week before I/R], wortmannin group(1 week before I/R, the PI3K inhibitor, wortmannin, was injected), EA pretreatment + wortmannin group(both pretreatments were performed simultaneously). After establishing the I/R model, 2,3,5-triphenyltetrazolium chloride(TTC) staining was used to analyze the weight and area of the myocardial infarction tissue.The biosignal and pressure test system was used to determine the left ventricular systolic mean pressure(LVSP), left ventricular end-diastolic pressure(LVEDP), fractional shortening(FS), and ejection fraction(EF). Ultraviolet spectrophotometry was used to determine the expression of creatine kinase(CK)-MB, inducible nitric oxide synthase(i NOS), and total antioxidant capacity(T-AOC) in the serum. The expression of autophagy-related protein 13(ATG13), mammalian target of rapamycin(m TOR), and phosphatidylinositol 3-kinase(PI3K) in cardiac muscle cells was determined by immunofluorescence. Hematoxylin and eosin staining was used to observe autophagy-related pathological changes in rat cardiomyocytes, and ultrastructural changes of cardiomyocytes were examined by transmission electron microscopy.RESULTS: In this study, the infarction size and tissue weight of the EA pretreatment group were decreased compared with the model group(P <0.0001). Furthermore, compared with the model group, the LVEDP values of the EA pretreatment group were significantly reduced(P = 0.0091), and the LVSP, FS, and EF values were slightly increased (P = 0.0007, 0.0020, 0.0031). EA pretreatment also significantly decreased the expression of CK-MB and i NOS, while it increased the expression of T-AOC in the serum of rats with I/R injury(P <0.0001). Furthermore, EA pretreatment slightly widened the myocardial fiber space, reduced necrosis and myocardial cell swelling and maintained the nucleus and mitochondria structure intact.CONCLUSION: EA pretreatment promoted autophagy flux and alleviated myocardial I/R injury through the PI3K-Akt-m TOR pathway. | HAN Yongli CHEN Song PENG Xingming | 2021 | Journal of Traditional Chinese Medicine2021,41,3: | 6 |
| 20 | Enhanced gas separation performance of mixed matrix hollow fiber membranes containing post-functionalized S-MIL-53显示文摘Mixed matrix hollow fiber membranes(MMHFMs)filled with metal-organic frameworks(MOFs)have great potential for energy-efficient gas separation processes,but the major hurdle is polymer/MOFs interfacial defects and membrane plasticization.Herein,lab-synthesized MIL-53 was post-functionalized by aminosilane grafting and subsequently incorporated into Ultem~?1000 polymer matrix to fabricate high performance MMHFMs.SEM,DLS,XRD and TGA were performed to characterize silane-modified MIL-53(S-MIL-53)and prepared MMHFMs.Moreover,the effect of MOFs loading was systematically investigated first;then gas separation performance of MMHFMs for pure and mixed gas was evaluated under different pressures.MMHFMs containing post-functionalized S-MIL-53 achieved remarkable gas permeation properties which was better than model predictions.Compared to pure HFMs,CO_2permeance of MMHFM loaded with 15%S-MIL-53 increased by 157%accompanying with 40%increase for CO_2/N_2selectivity,which outperformed the MMHFM filled with naked MIL-53.The pure and mixed gas permeation measurements with elevated feed pressure indicated that incorporation of S-MIL-53 also increased the resistance against CO_2plasticization.This work reveals that post-modified MOFs embedded in MMHFMs facilitate the improvement of gas separation performance and suppression of membrane plasticization. | Haitao Zhu Xingming Jie Lina Wang Guodong Kang Dandan Liu Yiming Cao | 2018 | Journal of Energy Chemistry2018,27,3: | 6 |