|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Xiaoqinglong decoction reduces dendritic cell differentiation and regulates the Th1/Th2 balance in a mouse model of allergic asthma显示文摘Background:Xiaoqinglong decoction(XQLD)is a classic Chinese medicinal formula that is widely used to treat allergic asthma.Recently,the use of XQLD to treat allergic asthma has inspired research to determine its mechanism of action.Because dendritic cells(DCs)and the T helper 1(Th1)/Th2 cytokine balance play important roles in allergic asthma,the present work aimed to assess how these immune system components are affected by XQLD.Methods:Thirty-six female BALB/C mice were randomly divided into three groups:an ovalbumin-based allergic asthma model group,a XQLD treatment group,and a control group.Histology was performed with haematoxylin and eosin staining and immunohistochemical staining.Bronchoalveolar lavage fluid and blood were collected from the animals and used to analyze the composition of inflammatory cells and expression levels of the cytokines interleukin(IL)-5 and IL-13.The thymic stromal lymphopoietin(TSLP)protein expression was assessed by western blot analysis,and the Gata3 and Tbx21 mRNA levels were assessed by polymerase chain reaction.Results:Compared with the OVA group,the levels of TSLP expression,IL-5,IL-13,and immunoglobulin E in the XQLD group were lower(all P<.01).The level of IL-4-expressing cells(Th2 cells)was lower(P=.0013),and the percentage of IFN-g-expressing cells(Th1 cells)was higher in the XQLD group compared with those in the OVA group(P=.0065).In addition,XQLD increased the expression of Tbx21 mRNA and decreased the expression of Gata3 mRNA in the lungs compared with the OVA group(both P<.01).Conclusion:These findings suggest that XQLD may ameliorate the course of allergic asthma by regulating the Gata3/Tbx21 balance and inhibiting TSLP expression,changes which are indicative of an altered Th1/Th2 balance.Thus,the clinical effectiveness of XQLD in treating allergic asthma may be due to its regulation of Th1/Th2 balance. | Juntang Yan Nan Deng Qingguo Wang Xin Du Changxiang Li Ting Xie Yanxia Liu Min Liu | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，2： | 2 |
| 2 | Preparing temperature-dependent dynamic rheological properties of polypropylene filled with ultra-fine powdered rubber显示文摘 | Zheng Qiang Cao Yanxia Du Miao | 2004 | J Mater Sci2004，39，5： | 1 |
| 3 | Enantioseparation by HPLC Using an Inorganic Chiral Mesoporous Silica with Highly-ordered Structure显示文摘Highly-ordered inorganic chiral mesoporous silica(HOCMS)has attracted substantial interest in recent decades.High performance liquid chromatography(HPLC)is the most important approach for the separation of enantiomers and herein reported an HPLC chiral stationary phase composed of HOCMS.The column was fabricated by conventional high pressure slurry packing.Eighteen racemates,including alcohols,ketones,amines,aldehydes and organic acids,were resolved on the column.Good chiral separations of hydrobenzoin,metoprolol,propranolol hydrochloride,4-methyl-2-pentanol,omeprazole,2,2′-furoin and ketoprofen were obtained.The relative standard devi-ations for five replicate separations of racemates were 0.1%–0.16%for retention time and 1.73%–2.64%for peak areas.The results suggest that HOCMS is a promising candidate for preparation of chiral stationary phases for HPLC. | PENG Bo FU Shiguo LI Yanxia ZHANG Junhui XIE Shengming LI Li LYU Yun DU AN Aihong CHEN Xuexian YUAN Liming | 2019 | Chemical Research in Chinese Universities2019，35，6： | 1 |
| 4 | Visible transparent,infrared stealthy polymeric films with nanocoating of ITO@MXene enable efficient passive radiative heating and solar/electric thermal conversion显示文摘Visible transparent yet low infrared-emissivity(ε)polymeric materials are highly anticipated in many applications,whereas the fabrication of which remains a formidable challenge.Herein,visible transparent,flexible,and low-εpolymeric films were fabricated by nanocoating decoration of indium tin oxide(ITO)and MXene on polyethylene terephthalate(PET)film surface through magnetron sputtering and spray coating,respectively.The obtained PET-ITO@MXene(PET-IM)film exhibits lowεof 24.7%and high visible transmittance exceeding 50%,endowing it with excellent visible transparent infrared stealthy by reducing human skin radiation temperature from 32 to 20.8°C,and remarkable zero-energy passive radiative heating capability(5.7°C).Meanwhile,the transparent low-εPET-IM film has high solar absorptivity and electrical conductivity,enabling superior solar/electric to thermal conversion performance.Notably,the three heating modes of passive radiative and active solar/electric can be integrated together to cope with complex heating scenarios.These visible transparent low-εpolymeric films are highly promising in infrared stealth,building daylighting and thermal management,and personal precision heating. | Xingyuan Du Xiangxin Li Yuxuan Zhang Xinyi Guo Zhengji Li Yanxia Cao Yanyu Yang Wanjie Wang Jianfeng Wang | 2023 | Nano Research2023，16，2： | 1 |
| 5 | The role of macrophage reprogramming induced by GRA15II,a polypeptide effector molecule of Toxoplasma gondii,in liver diseases in model mice显示文摘Toxoplasma gondii is a widespread parasite that may infect nearly all warm-blooded vertebrates.1 As an obligatory intracellular apicomplexan parasite,T.gondii has three different types of secretory organelles,including micronemes,rhoptries(ROP),and dense granules(GRAs),during invasion of host cells.2 Initially,the parasite replicates in a variety of host cell types as tachyzoites,especially in macrophages and dendritic cells(DCs). | Yihong Cai Yanxia Yu Yanling Wang Yuan Zhang Qingli Luo Li Yu Jian Du Deyong Chu Jilong Shen | 2020 | Cellular & Molecular Immunology2020，17，7： | 1 |
| 6 | Characteristics of secondary droplets produced by the impact of drops onto a smooth surface显示文摘This work investigates the splashing behaviors of droplets impacting on solid surfaces and mainly focuses on the characteristics of secondary droplets.According to the experimental results,two different splashing patterns,corona splash and levitating-lamella breakup,are observed.A new breakup mode,named rimsegmenting,is found during the levitating-lamella breakup.In particular,the detailed information of the splashing secondary droplets,including the size,velocity,angle,and total volume of the splashing secondary droplets is obtained from the experimental data.The size distribution of the splashing secondary droplets obeys the gamma distribution function.The average diameter and splashing angle of the secondary droplets are mainly related to the Reynolds number Re,and can be expressed as functions of Re.High impact velocity and liquid viscosity will result in a wider size distribution range of splashing secondary droplets.We also put forward an empirical model to predict the total splashing volume,which is consistent with the experimental data both in this work and previous studies.This work is believed to provide insights on the prediction of the characteristics of splashing secondary droplets. | Haixiang Zhang Ye Gao Xiwen Zhang Xian Yi Yanxia Du Feng He Zheyan Jin Pengfei Hao | 2021 | Advances in Aerodynamics2021，3，1： | 1 |
| 7 | Investigation of transfer ionization processes in the collision of partially stripped carbon ions on Argon显示文摘The ratios of the cross section of the transfer-ionization to the single-electron-capture of Argon induced by Cq+ (q=1,2,3) ions are measured by means of position sensitive and time-of-flight techniques. Our experimental results are compared with the data of Heq+ (q=1,2)-Ar of DuBois. A qualitative interpretation is presented based on the Classical-Over-Barrier Model of Bohr. | WANG Jun CHEN XiMeng DING BaoWei FU HongBin CUI Ying SHAO JianXiong LU YanXia GAO ZhiMin LIU YuWen Du Juan SUN GuangZhi CHEN Lin | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，7： | 0 |
| 8 | Influence of Metal Material Properties on Heat and Mass Transfer into Thermal Protection Surface with Phenomenological Catalytic Model显示文摘Surface heterogeneous catalysis in a high-enthalpy dissociated environment leads to a remarkable enhancement of aerodynamic heating into the thermal protection surface of hypersonic aircraft.To more accurately predict this catalytic heating,a kinetic catalytic model was constructed.This model involved four elementary reactions,the rates of which were determined on mean-field approximation and surface steady-state reaction assumption.By coupling this model into the viscous wall boundary condition of computational fluid dynamics(CFD)solver,the influences of metal material catalytic properties on heat and mass transfer into thermal protection materials were numerically investigated.Numerical results showed that atomic oxygen recombination catalyzed by surface material accounts for a major contribution to aerodynamic heating and thus variation in recombination rates from different materials leads to the significant difference in surface heat fluxes.From a comparative analysis of various materials,the catalytic activity increases from the inert platinum(Pt)to nickel(Ni)and finally to the active copper(Cu).As a result,the catalytic heating on Cu surface was more than twice of that on Pt surface.Further parametrical research revealed that the proper layout of inert material at the nose of aircraft could prevent stagnation catalytic heating from thermal damage by carrying near-wall dissociated atoms from the stagnation zone downstream.The material-relied heterogeneous catalysis mechanism in this study provides some technical support for the thermal protection system design of hypersonic aircraft. | LI Qin YANG Xiaofeng DONG Wei DU Yanxia | 2023 | Journal of Thermal Science2023，32，3： | 0 |
| 9 | Enriching the surface oxygen as efficient anchoring site of highly dispersed Ru for enhanced hydrogenolysis activity显示文摘While supported-noble-metal catalysts have been widely investigated in hydrotreating reactions,a crucial issue that the catalytic system is still confronted with is developing an efficient approach to gain the high dispersion of noble metals under reducing conditions.In this work,Ru was supported on two MnOx with different specific surface areas(SSAs),and a much higher dispersion of Ru(83%,in contrast to 42%of the other one)was surprisingly observed over MnO with much lower SSA(around one-third of the other one).A suite of complementary characterizations demonstrates that,compared with the catalyst with high SSA(Ru/MnO-H),the MnO in the one with lower SSA(Ru/MnO-L)contains enriched surface oxygen that creates more abundant sites and bears stronger strength to anchor Ru species,mitigating the aggregation of Ru under reducing condition.This not only enriched active sites(i.e.,exposed Ru),but also created a more electron-deficient Ru domain and thus enhanced the redox property of the surface,leading to the lower barrier for C–O bond hydrogenolysis.In the hydrogenolysis of diphenyl ether,Ru/MnO-L exhibited significantly enhanced activity(i.e.,6 folds of Ru/MnO-H)and high stability.This work provides an approach to regulate the surface chemistry of support for the high dispersion of supported metal. | Hongfei Xiao Jianghao Zhang Chuo Du Yanxia Zheng Shuchao Ge Jinhou Fang Shuang Li Changbin Zhang | 2023 | Nano Research2023，16，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员