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| 1 | Research Progress of Value, Extraction and Applicationof Silkworm Chrysalis Protein显示文摘Silkworm chrysalis protein is a high quality pure natural complete animal protein with high utilization value, and it has been widely used in many industries in recent years. The nutrition, health care and medicinal value of silkworm chrysalis protein, the degreasing, deodorization and decoloration extraction process, and its application in food, medicine, feed, etc. are summarized, in order to provide the reference for further development and industrial production of silkworm chrysalis protein. | zhang yuping zhang lili chen ming dai junjun wu chuanhua liu jian fan tao yin jianli | 2018 | Animal Husbandry and Feed Science2018，10，4： | 2 |
| 2 | PORK PRODUCTION SYSTEMS IN CHINA:A REVIEW OF THEIR DEVELOPMENT,CHALLENGES AND PROSPECTS IN GREEN PRODUCTION显示文摘This paper reviews the changes in pork production in China,the largest pork producing and consuming nation in the world.The pork sector in China has changed dramatically since the 1990s,with large-scale intensive pork production systems replacing the former,exclusively family-based pork production systems.Modern breeding,feeding,vaccinating,and management technologies are widely used now.However,smallholders still account for a large proportion of the total production.The intensification and specialization of the pork sector is expected to continue in the future,but there is increasing awareness and pressure to develop more environmentally-sustainable production systems.The relative shortage of domestically produced feed,the low utilization efficiency of feed ingredients,the large emissions of nitrogen and phosphorus to the environment,the high use of antibiotics,and the presence of residual metals in manures are very large challenges for the pork sector nowadays.To solve these problems,techniques including new feed resource utilization,precise feeding,low-protein diets,alternatives to antibiotics and increased manure recycling are all important topics and research directions today.With new techniques and management approaches,it is possible to build more sustainable pork production systems in China. | Shuai ZHANG Xin WU Dandan HAN Yong HOU Jianzhuang TAN Sung Woo KIM Defa LI Yulong YIN Junjun WANG | 2021 | Frontiers of Agricultural Science and Engineering2021，8，1： | 2 |
| 3 | Characterizing the human mobility pattern in a large street network显示文摘 | JIANG Bin YIN Junjun ZHAO Sijian | 2009 | Physical Review E2009，80，02： | 1 |
| 4 | Systematic analysis of clinical relevance and molecular characterization of m^(6)A in COVID-19 patients显示文摘N6-methyladenosine(m6A)is the most prevalent post-transcriptional RNA modification in mRNA and long non-coding RNAs of eukaryotes,and its biological functions are mediated by m6A writers,erasers and readers.1 A nuclear methyltransferase complex consisting of METTL3,METTL14,WTAP,VIRMA,ZC3H13,RBM15(or RBM15B),YWHAG,TRA2A and CAPRIN1 catalyzes the m6A modifications,acting as m6A writers.1 m6A demethylase ALKBH5 as well as m6A demethylase FTO mediate the demethylation of m6As,acting as the m6A erasers. | Sanqi An Zhouhua Xie Yanyan Liao Junjun Jiang Wenyi Dong Fuqiang Yin Wen-Xing Li Li Ye Jianyan Lin Hao Liang | 2022 | Genes & Diseases2022，9，5： | 1 |
| 5 | Self-organized natural roads for predicting traffic flow: a sensitivity study显示文摘 | Bin Jiang Sijian Zhao Junjun Yin | 2008 | Journal of Statistical Mechanics: Theory and Expe2008，，07： | 1 |
| 6 | Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells显示文摘 | Kang Yao Yulong Yin Xilong Li Pengbin Xi Junjun Wang Jian Lei Yongqing Hou Guoyao Wu | 2012 | Amino Acids2012，，6： | 1 |
| 7 | Self-organized Natural Roads for Predicting Traffic Flow:A Sensitivity Study显示文摘 | Jiang Bin Zhao Sijian Yin Junjun | 2008 | Journal of Statistical Mechanics:Theory and Experiment2008，，7： | 1 |
| 8 | High - tem- perature press swing adsorption process for CO2 separa- tion 显示文摘 | Yin Junjun Qin Changlei An Hui | 2012 | Energy&fuels2012，26，： | 1 |
| 9 | Self-organized Natural Roads for Predicting Traffic Flow: A Sensi- tivity Study显示文摘 | Jiang Bin Zhao Sijian Yin Junjun | 2008 | Journal of Statistical Mechanics: Theory and Experiment2008，，7： | 1 |
| 10 | Proteomic analysis reveals altered expression of proteins related to glutathione metabolism and apoptosis in the small intestine of zinc oxide-supplemented piglets显示文摘 | Xiaoqiu Wang Deyuan Ou Jingdong Yin Guoyao Wu Junjun Wang | 2009 | Amino Acids2009，，1： | 1 |
| 11 | Catabolism of nutritionally essential amino acids in developing porcine enterocytes显示文摘 | Lixiang Chen Peng Li Junjun Wang Xilong Li Haijun Gao Yulong Yin Yongqing Hou Guoyao Wu | 2009 | Amino Acids2009，，1： | 1 |
| 12 | Self-organized Natural Roads for Predicting Traffic Flow:A Sensitivity Study显示文摘 | Jiang Bin Zhao Sijian Yin Junjun | | 0，，： | 1 |
| 13 | Conjugate Hydrocyanation of Chalcone Derivatives Using Ethyl Cyanoacetate as an Organic Cyanide Source显示文摘 | Zheng Li Junjun Yin | 2017 | Chinese Journal of Chemistry2017，35，7： | 1 |
| 14 | Urban air quality and regional haze weather forecast for Yangtze River Delta region显示文摘 | Tijian Wang Fei Jiang Junjun Deng Yi Shen Qinyan Fu Qian Wang Yin Fu Jianhua Xu Danning Zhang | 2012 | Atmospheric Environment2012，，： | 1 |
| 15 | LRH-1 senses signaling from phosphatidylcholine to regulate the expansion growth of digestive organs via synergy with Wnt/β-catenin signaling in zebrafish显示文摘Liver receptor homolog-1(LRH-1)is an orphan nuclear receptor that is critical for the growth and proliferation of cancer cells and other biological processes,including lipid transportation and metabolism,sexual determination and steroidogenesis.However,because homozygous lrh-1^(-/-) mice die in utero,the regulatory mechanisms involved in embryonic development mediated by this receptor are poorly understood.In the present study,we performed transcription activator-like effector nuclease(TALEN)-mediated loss-of-function assays,taking advantage of zebrafish external fertilization,to investigate the function of lrh-1.The digestive organs were affected by lrh-1 depletion as a result of cellcycle arrest(at the checkpoint of G1 to S phase),but not cell apoptosis.Biochemical analysis revealed that LRH-1 augments the transcriptional activity of b-catenin 1 and 2 via physical interactions.Screening the specific ligand(s)sensed by LRH-1 during organogenesis revealed that phosphatidylcholine(PC),a potential ligand,is the upstream target of LRH-1 during endoderm development.These data provide evidence for the crosstalk between the PC/LRH-1 and Wnt/β-catenin signaling pathways during the expansion growth of endoderm organs. | Gang Zhai Jia Song Tingting Shu Junjun Yan Xia Jin Jiangyan He Zhan Yin | 2017 | Journal of Genetics and Genomics2017，44，6： | 0 |
| 16 | USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia显示文摘T-cell acute lymphoblastic leukemia(T-ALL)is a highly aggressive leukemia that is primarily caused by aberrant activation of the NOTCH1 signaling pathway.Recent studies have revealed that posttranslational modifications,such as ubiquitination,regulate NOTCH1 stability,activity,and localization.However,the specific deubiquitinase that affects NOTCH1 protein stability remains unestablished.Here,we report that ubiquitin-specific protease 7(USP7)can stabilize NOTCH1.USP7 deubiquitinated NOTCH1 in vivo and in vitro,whereas knockdown of USP7 increased the ubiquitination of NOTCH1.USP7 interacted with NOTCH1 protein in T-ALL cells,and the MATH and UBL domains of USP7 were responsible for this interaction.Depletion of USP7 significantly suppressed the proliferation of T-ALL cells in vitro and in vivo,accompanied by downregulation of the NOTCH1 protein level.Similarly,pharmacologic inhibition of USP7 led to apoptosis of T-ALL cells.More importantly,we found that USP7 was significantly upregulated in human T-ALL cell lines and patient samples,and a USP7 inhibitor exhibited cell cytotoxicity toward primary T-ALL cells,indicating the clinical relevance of these findings.Overall,our results demonstrate that USP7 is a novel deubiquitinase that stabilizes NOTCH1.Therefore,USP7 may be a promising therapeutic target in the currently incurable T-ALL. | Huizhuang Shan Xiangyun Li Xinhua Xiao Yuting Dai Jinyan Huang Junjun Song Meng Liu Li Yang Hu Lei Yin Tong Li Zhou Hanzhang Xu Yingli Wu | 2018 | Signal Transduction and Targeted Therapy2018，3，1： | 0 |
| 17 | A comprehensive first-principle study of borophene-based nano gas sensor with gold electrodes显示文摘Using density functional theory combined with nonequilibrium Green’s function method,the transport properties of borophene-based nano gas sensors with gold electrodes are calculated,and comprehensive understandings regarding the effects of gas molecules,MoS2 substrate and gold electrodes to the transport properties of borophene are made.Results show that borophene-based sensors can be used to detect and distinguish CO,NO,NO2 and NH3 gas molecules,MoS2 substrate leads to a nonlinear behavior on the current-voltage characteristic,and gold electrodes provide charges to borophene and form a potential barrier,which reduced the current values compared to the current of the systems without gold electrodes.Our studies not only provide useful information on the computationally design of borophene-based gas sensors,but also help understand the transport behaviors and underlying physics of 2D metallic materials with metal electrodes. | Yueyue Tian Houping Yang Junjun Li Shunbo Hu Shixun Cao Wei Ren Yin Wang | 2022 | Frontiers of physics2022，17，1： | 0 |
| 18 | Tet酶调控端粒和基因组稳定性的作用和机制显示文摘Tets家族催化5-甲基胞嘧啶转变为5-羟甲基胞嘧啶。在小鼠胚胎干细胞中单独干扰Tet1或/和Tet2,伴随着端粒重组下降,导致端粒长度缩短和基因组稳定性异常。 | Jiao Yang Renpeng Guo Hua Wang Xiaoying Ye Zhongcheng Zhou Jiameng Dan Haiying Wang Peng Gong Wei Deng Yu Yin Shi Qing Mao Lingbo Wang Junjun Ding Jinsong Li David L.Keefe Meelad M.Dawlaty Jianlong Wang Guo Liang Xu 刘林 | 2017 | 科学新闻2017，19，4： | 0 |
| 19 | Influence analysis of calculated horizontally layered soil parameters on grounding parameters显示文摘Calculated parameters(soil layer resistivity,soil layer thickness,and the number of soil layers)of horizontally layered soil are usually obtained based on the measured apparent resistivity under different measurement distances,which are significant for the design,operation,and maintenance of grounding grids.Most existing calculation methods of soil parameters are just trying to make the calculation results approach the measurement data,ignoring the relationship among measurement data,the calculated soil parameters,and grounding parameters,which would increase the workload of the measurement.To better balance the distance range of the measurement data and the influence of the calculated horizontally layered soil on grounding parameters,this paper systematically studies the relationship among measured apparent soil resistivity,calculated horizontally layered soil parameters,and grounding parameters.The basic theories of apparent resistivity measurement,soil parameter calculation,and grounding parameter calculation are given,the influence of soil layer thickness on the measured apparent resistivity is studied,and the influence of the calculated soil parameters on the grounding resistance of different grounding models is analysed.Based on different scales of grounding grids,the results give a corresponding reference distance range of measured apparent soil resistivity.Therefore,this paper can help decrease the workload of soil resistivity measurement during grounding parameters analysis,which has far-reaching engineering significance. | Yihua Dan Junjun Yin Jian Yang Huizhang Yang | 2023 | High Voltage2023，8，2： | 0 |
| 20 | Gut microbiota bridges dietary nutrients and host immunity显示文摘Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and entrain each other,and thus affect host health and immune-mediated diseases.Here,we systematically review the current understanding linking dietary nutrients to gut microbiota-host immune interactions,emphasizing how this axis might influence host immunity in health and diseases.Of relevance,we highlight that the implications of gut microbiota-targeted dietary intervention could be harnessed in orchestrating a spectrum of immune-associated diseases. | Lijuan Fan Yaoyao Xia Youxia Wang Dandan Han Yanli Liu Jiahuan Li Jie Fu Leli Wang Zhending Gan Bingnan Liu Jian Fu Congrui Zhu Zhenhua Wu Jinbiao Zhao Hui Han Hao Wu Yiwen He Yulong Tang Qingzhuo Zhang Yibin Wang Fan Zhang Xin Zong Jie Yin Xihong Zhou Xiaojun Yang Junjun Wang Yulong Yin Wenkai Ren | 2023 | Science China(Life Sciences)2023，66，11： | 0 |
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