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| 1 | Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased. | NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng | 2012 | Chinese Science Bulletin2012，57，22： | 51 |
| 2 | Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma显示文摘MicroRNAs 是否定地在 post-transcriptional 水平调制基因表示的短规章的 RNA,并且深深地涉及癌症的几种类型的致病。调查特定的 miRNAs 和他们的目标基因是否参予喉的癌的分子的致病, oligonucleotide microarrays 被用来与正常纸巾相比在喉的癌纸巾估计 microRNAs 和 mRNAs 的微分表示侧面。oncogenic miRNA, microRNA-21 (miR-21 ) ,被发现是在喉的癌纸巾的 upregulated。由特定的 antisense oligonucleotides 的 miR-21 击倒而 miR-21 的 overexpression 提高了细胞的生长活动,由殖民地形成试金检测了,禁止了 HEp-2 细胞的增长潜力。miR-21 抑制引起的房间数字减小由于 G1-S 阶段转变的控制的损失,而不是 apoptosis 的显著增加。随后, miR-21 的新目标基因, BTG2,被发现是在喉的癌纸巾的 downregulated。BTG2 被知道充当一个平底锅房间周期管理者和肿瘤 suppressor。这些调查结果显示 miR-21 的那异常表情可以由维持 BTG2 的底层贡献喉的癌的恶意的显型。oncogenic miR-21 和它的目标基因的鉴定, BTG2,为癌症诊断和治疗在喉的癌是潜在地珍贵的。 | Min Liu Haidong Wu Tao Liu Yixuan Li Fang Wang Haiying Wan Xin Li Hua Tang | 2009 | Cell Research2009，19，7： | 40 |
| 3 | Reliability Assessment Considering the Coordination of Wind Power, Solar Energy and Energy Storage显示文摘风光储联合发电系统并网后必须采取策略与系统之间实现协调调度与运行才可在保证可靠性的前提下最大化利用可再生能源,但现有的可靠性评估中还缺少对大规模风光储联合发电系统协调运行的考虑。针对此问题,基于序贯蒙特卡罗仿真方法,建立了风电、光伏和储能系统的发电可靠性评估模型,并提出了新的协调调度策略。模型综合考虑了风速、太阳光辐照度、环境温度以及2种新能源发电技术的能量变换特性和储能系统的充放电约束等因素。这些模型被应用到IEEERTS79中,通过在Matlab中编制程序进行仿真计算,考察不同的协调运行策略、联合发电系统容量配置以及储能特性对于系统裕度的影响。评估结果可为联合发电系统并网规划与设计提供参考。 | WANG Haiying BAI Xiaomin XU Jing | 2012 | 中国电机工程学报2012，32，13： | 35 |
| 4 | The first all-season sample set for mapping global land cover with Landsat-8 data显示文摘We report the world's first all-season training and validation sample sets for global land cover classification with Landsat-8 data.Prior to this,such samples were only available at a single date primarily from the growing season.It is unknown how much limitation such a single-date sample has to mapping global land cover in other seasons of the year.To answer this question,we selected available Landsat-8 images from four seasons and collected training and validation samples from them.We compared the performances of training samples in different seasons using Random Forest algorithm.We found that the use of training samples from any individual season would result in the best overall classification accuracy when validated by samples in the same season.The global overall accuracy from combined best seasonal results was 67.2% when classifying the 11 Level-1 classes in the Finer Resolution Observation and Monitoring of Global Land Cover(FROM-GLC) classification system.The use of training samples from all seasons(named all-season training sample set hereafter) produced an overall accuracy of 67.0%.We also tested classification within 10° latitude 60° longitude zones using all-season training subsample within each zone and obtained an overall accuracy of 70.2%.This indicates that properly grouped subsamples in space can help improve classification accuracies.All the results in this study seem to suggest that it is possible to use an all-season training sample set to reach global optimality with universal applicability in classifying images acquired at any time of a year for global land cover mapping. | Congcong Li Peng Gong Jie Wang Zhiliang Zhu Gregory S. Biging Cui Yuan Tengyun Hu Haiying Zhang Qi Wang Xuecao Li Xiaoxuan Liu Yidi Xu Jing Guo Caixia Liu Kwame O. Hackman Meinan Zhang Yuqi Cheng Le Yu Jun Yang Huabing Huang Nicholas Clinton | 2017 | Science Bulletin2017，62，7： | 21 |
| 5 | Ozone sensitivity analysis with the MM5-CMAQ modeling system for Shanghai显示文摘Ozone has become one of the most important air pollution issues around the world. This article applied both O 3 /(NOy-NOx) and H 2 O 2 /HNO 3 indicators to analyze the ozone sensitivity in urban and rural areas of Shanghai, with implementation of the MM5-CMAQ modeling system in July, 2007. The meteorological parameters were obtained by using the MM5 model. A regional emission inventory with spatial and temporal allocation based on the statistical data has been developed to provide input emission data to the MM5-CMAQ modeling system. Results showed that the ozone concentrations in Shanghai show clear regional differences. The ozone concentration in rural areas was much higher than that in the urban area. Two indicators showed that ozone was more sensitive to VOCs in urban areas, while it tended to be NOx sensitive in rural areas of Shanghai. | Li Li Changhong Chen Cheng Huang Haiying Huang Gangfeng Zhang Yangjun Wang Minghua Chen Hongli Wang Yiran Chen D. G. Streets Jiamo Fu | 2011 | Journal of Environmental Sciences2011，23，7： | 18 |
| 6 | Influence of Water Stress on Endogenous Hormone Contents and Cell Damage of Maize Seedlings显示文摘Phytohormones play critical roles in regulating plant responses to stress. We investigated the effects of water stress induced by adding 12% (w/v) polyethylene glycol to the root medium on the levels of abscisic acid (ABA), indole-3-acid (IAA), zeatin (ZT), and gibberellin3 (GA3) in maize leaves. The results suggested that water stress had significant effects on the four hormone levels. There was a transient increase in the IAA content during the initial stage of adaptation to water stress in maize leaves, but it dropped sharply thereafter in response to water stress. ABA content increased dramatically in maize leaves after 24 h of exposure to water stress, and then the high levels of ABA were maintained to the end. The contents of ZT and GA3 rapidly declined in maize leaves subjected to water stress. The effects of water stress on chlorophyll content, electrolyte leakage and malondialdehyde levels in maize leaves were also studied. The variation of cell damage was negatively correlated with ZT and GA3 levels in maize leaves under water stress. Thus, we explored the roles of ZT and GA3 on the growth of maize seedlings under water stress by exogenous application. It is possible that both ZT and GA3 were effective in protecting maize seedlings from water stress, which would be of great importance for the improvement of drought tolerance in maize by genetic manipulation. | Chunrong Wang Aifang Yang Haiying Yin Juren Zhang | 2008 | Journal of Integrative Plant Biology2008，50，4： | 17 |
| 7 | FREQUENTIST MODEL AVERAGING ESTIMATION:A REVIEW显示文摘In applications, the traditional estimation procedure generally begins with model selection.Once a specific model is selected, subsequent estimation is conducted under the selected model withoutconsideration of the uncertainty from the selection process. This often leads to the underreportingof variability and too optimistic confidence sets. Model averaging estimation is an alternative to thisprocedure, which incorporates model uncertainty into the estimation process. In recent years, therehas been a rising interest in model averaging from the frequentist perspective, and some importantprogresses have been made. In this paper, the theory and methods on frequentist model averagingestimation are surveyed. Some future research topics are also discussed. | Haiying WANG Xinyu ZHANG Guohua ZOU Academy of Mathematics and Systems Science,Chinese Academy of Sciences,Beijing 100190,China. | 2009 | Journal of Systems Science & Complexity2009，22，4： | 14 |
| 8 | Enhanced Invasive and Metastatic Potential Induced by Transforming Growth Factor-β1 Might be Correlated with Glutathione-S-transferase-π, Cofilin and Heat Shock Protein 27 in SGC-7901 Gastric Cancer Cells显示文摘在我们的以前的学习,我们发现转变生长因素(TGF )-beta1 提高了胃的癌症房间的变形、侵略的潜力。Proteomics 在这研究被采用进一步说明内在的分子的机制。Aftertwo 维的电气泳动,图象分析,点鉴定,蛋白质鉴定和数据库分析,三蛋白质也就是, glutathione-S-transferase-pi (GST-pi ) , cofilin 和热震惊蛋白质 27 (HSP27 ) ,被发现在 TGF-beta1 起来调整对待的 SGC-7901 房间。Thefindings 被蛋白质印迹分析进一步证实。这些结果建议 GST-pi, cofilin 和 HSP27 可能参予 TGF-beta1 导致的提高的侵略潜力。 | Kuansong WANG Jinghe LI Changli ZHEN Jianhua ZHOU Desheng XIAO Jie LIU Ying LIU Haiying JIANG Chen CHEN Jifang WEN | 2007 | Acta Biochimica et Biophysica Sinica2007，39，7： | 11 |
| 9 | Evaluation of Two Momentum Control Variable Schemes and Their Impact on the Variational Assimilation of Radar Wind Data:Case Study of a Squall Line显示文摘Different choices of control variables in variational assimilation can bring about different influences on the analyzed atmospheric state.Based on the WRF model's three-dimensional variational assimilation system,this study compares the behavior of two momentum control variable options—streamfunction velocity potential(ψ–χ) and horizontal wind components(U–V)—in radar wind data assimilation for a squall line case that occurred in Jiangsu Province on 24 August 2014.The wind increment from the single observation test shows that the ψ–χ control variable scheme produces negative increments in the neighborhood around the observation point because streamfunction and velocity potential preserve integrals of velocity.On the contrary,the U–V control variable scheme objectively reflects the information of the observation itself.Furthermore,radial velocity data from 17 Doppler radars in eastern China are assimilated.As compared to the impact of conventional observation,the assimilation of radar radial velocity based on the U–V control variable scheme significantly improves the mesoscale dynamic field in the initial condition.The enhanced low-level jet stream,water vapor convergence and low-level wind shear result in better squall line forecasting.However,the ψ–χ control variable scheme generates a discontinuous wind field and unrealistic convergence/divergence in the analyzed field,which lead to a degraded precipitation forecast. | Xin LI Mingjian ZENG Yuan WANG Wenlan WANG Haiying WU Haixia MEI | 2016 | Advances in Atmospheric Sciences2016，33，10： | 10 |
| 10 | PandaX: a liquid xenon dark matter experiment at CJPL显示文摘PandaX is a large liquid-xenon detector experiment usable for direct dark-matter detection and 136Xe double-beta decay search.The central vessel was designed to accommodate a staged target volume increase from initially 120 kg(stage I)to 0.5 t(stage II)and eventually to a multi-ton scale.The experiment is located in the Jinping Deep-Underground Laboratory in Sichuan,China.The detector operates in dual-phase mode,allowing detection of both prompt scintillation,and ionization charge through proportional scintillation.In this paper a detailed description of the stage I detector design and performance as well as results established during the commissioning phase are presented. | CAO XiGuang CHEN Xun CHEN YunHua CUI XiangYi FANG DeQing FU ChangBo GIBONI Karl L. GONG HaoWei GUO GuoDong HE Ming HU Jie HUANG XingTao JI XiangDong JU YongLin LI ShaoLi LIN Qing LIU HuaXuan LIU JiangLai LIU Xiang LORENZON Wolfgang MA YuGang MAO YaJun NI KaiXuan PUSHKIN Kirill REN XiangXiang SCHUBNELL Michael SHEN ManBing SHI YuJie STEPHENSON Scott TAN AnDi TARLé Greg WANG HongWei WANG JiMing WANG Meng WANG XuMing WANG Zhou WEI YueHuan WU ShiYong XIAO MengJiao XIAO Xiang XIE PengWei YE Tao YOU YingHui ZEN XiongHui ZHANG Hua ZHANG Tao ZHAO HaiYing ZHAO Li ZHOU XiaoPeng ZHU ZhongHua | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 9 |
| 11 | Integrated analysis of transcriptomic and proteomic data from tree peony(P.ostii)seeds reveals key developmental stages and candidate genes related to oil biosynthesis and fatty acid metabolism显示文摘Tree peony(Paeonia section Moutan DC.)seeds are an excellent source of beneficial natural compounds that promote health,and they contain high levels of alpha-linolenic acid(ALA).In recent years,tree peony has been emerging as an oil crop.Therefore,combined analysis of the transcriptome and proteome of tree peony(P.ostii)seeds at 25,32,39,53,67,81,88,95,and 109 days after pollination(DAP)was conducted to better understand the transcriptional and translational regulation of seed development and oil biosynthesis.A total of 38,482 unigenes and 2841 proteins were identified.A total of 26,912 differentially expressed genes(DEGs)and 592 differentially expressed proteins(DEPs)were clustered into three groups corresponding to the rapid growth,seed inclusion enrichment and conversion,and late dehydration and mature stages of seed development.Fifteen lipid metabolism pathways were identified at both the transcriptome and proteome levels.Pathway enrichment analysis revealed that a period of rapid fatty acid biosynthesis occurred at 53–88 DAP.Furthermore,211 genes and 35 proteins associated with the fatty acid metabolism pathway,63 genes and 11 proteins associated with the biosynthesis of unsaturated fatty acids(UFAs),and 115 genes and 24 proteins associated with ALA metabolism were identified.Phylogenetic analysis revealed that 16 putative fatty acid desaturase(FAD)-encoding genes clustered into four FAD groups,eight of which exhibited the highest expression at 53 DAP,suggesting that they play an important role in ALA accumulation.RT-qPCR analysis indicated that the temporal expression patterns of oil biosynthesis genes were largely similar to the RNA-seq results.The expression patterns of fatty acid metabolism-and seed development-related proteins determined by MRM were also highly consistent with the results obtained in the proteomic analysis.Correlation analysis indicated significant differences in the number and abundance of DEGs and DEPs but a high level of consistency in expression patterns and metabolic pathways.The results of the present study represent the first combined transcriptomic and proteomic analysis of tree peony seeds and provide insight into tree peony seed development and oil accumulation. | Xiaojing Wang Haiying Liang Dalong Guo Lili Guo Xiangguang Duan Qishi Jia Xiaogai Hou | 2019 | Horticulture Research2019，6，1： | 9 |
| 12 | Compound Formula Rehmannia alleviates levodopainduced dyskinesia in Parkinson's disease显示文摘Compound Formula Rehmannia has been shown to be clinically effective in treating Parkinson's disease and levodopa-induced dyskinesia; however,the mechanisms remain unclear.In this study,we established a model of Parkinson's disease dyskinesia in rats,and treated these animals with Compound Formula Rehmannia.Compound Formula Rehmannia inhibited the increase in mRNA expression of N-methyl-D-aspartate receptor subunits 1 and 2 and excitatory amino acid neurotransmitter genes,and it inhibited the reduction in expression of γ-aminobutyric acid receptor B1,an inhibitory amino acid neurotransmitter gene,in the corpus striatum.In addition,Compound Formula Rehmannia alleviated dyskinesia symptoms in the Parkinson's disease rats.These experimental findings indicate that Compound Formula Rehmannia alleviates levodopa-induced dyskinesia in Parkinson's disease by modulating neurotransmitter signaling in the corpus striatum. | Long Teng Fang Hong Chenguang Zhang Jiancheng He Haiying Wang | 2014 | Neural Regeneration Research2014，9，4： | 8 |
| 13 | Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells显示文摘有各种各样的长度的 telomeres 的返老还童在导致的 pluripotent 干细胞(iPSCs ) 被发现了。telomere 长度规定的机制在 iPSCs 的正式就职和增长期间留下逃犯。我们证明 telomere 动力学在 reprogramming 和经过期间在鼠标 iPSCs 是可变的,并且建议这些差别多半源于多重潜在的因素,包括包括外长的 reprogramming 因素的表示的 telomerase 机械, telomerase 独立的机制和同种细胞的影响。用一个基因模型 telomerase 缺乏(为 iPSCs 的推导和段落的 Terc −/− 和 Terc +/−) 房间,我们发现 telomerase 在 iPSCs 的 reprogramming 和自强起一个关键作用。进一步,当由再结合的延伸和维护的其他的小径也被要求时, telomeres 的 telomerase 维护为真 pluripotency 的正式就职是必要的,然而并非足够。一起, telomere 生物学的几个方面可以在 iPSCs 说明可变 telomere 动力学。尤其是,采用在 iPSC reprogramming 期间维持 telomeres 的机制很类似于胚胎的干细胞的那些。这些调查结果可以也联系到这些机制能为在由体的房间的原子 reprogramming 以后的 telomere 异质负责的克隆的地原子转移。 | Fang Wang Yu Yin Xiaoying Ye Kai Liu Haiying Zhu Lingling Wang Maria Chiourea Maja Okuka Guangzhen Ji Jiameng Dan Bingfeng Zuo Minshu Li Qian Zhang Na Liu Lingyi Chen Xinghua Pan Sarantis Gagos David L Keefe Lin Liu | 2012 | Cell Research2012，22，4： | 7 |
| 14 | Inhibition of miR-144-3p exacerbates non-small cell lung cancer progression by targeting CEP55显示文摘Increasing evidence has indicated that microRNA dysregulation is closely related to the occurrence and development of cancers.Herein,we investigated the relationship between miR-144-3p&CEP55 expression.We then evaluated the association between miR-144-3p&CEP55 expression,&proliferation,invasion&apoptosis of non-small cell lung cancer[NSCLC]cells.Real-time quantitative PCR results revealed that CEP55 was over-expressed whereas miR-144-3p was underexpressed in NSCLC tissues.CCK-8 assay,wound healing assay,&flow cytometry further revealed that overexpression of miR-144-3p significantly inhibited proliferation&migration,but promoted apoptosis of A549 cells.Conversely,inhibition of miR-144-3p promoted proliferation. | Ming Li Yannan Liu Xinglin Jiang Yuanxin Hang Haiying Wang Hang Liu Zhuo Chen Yubo Xiao | 2021 | Acta Biochimica et Biophysica Sinica2021，53，10： | 7 |
| 15 | Long baroclinic Rossby waves with periods of about 500 d near 20°N in the northwest Pacific Ocean显示文摘On the basis of maps of sea level anomalies data set from October 1992 to January 2004, pronounced low frequency variations with periods of about 500 d are detected in the area near 20°N from 160°W to 130°E. A linear two-layer model is employed to explain the mechanism. It is found that the first-mode long baroclinic Rossby waves at 20°N in the northwest Pacific propagate westward in the form of free waves at a speed of about 10.3 cm/s. This confirms that the observed low frequency variabilities appear as baroclinic Rossby waves. It further shows that these low frequency variabilities around 20°N in the northwest Pacific can potentially be predicted with a lead up to 900 d. | CHEN Haiying QIAO Fangli FANG Guohong WANG Yonggang WEI Zexun | 2006 | Acta Oceanologica Sinica2006，25，3： | 6 |
| 16 | Toxic effects of 1-methyl-3-octylimidazolium bromide on the wheat seedlings显示文摘The toxic effects of 1-methyl-3-octylimidazolium bromide ([C8 mim]Br) on wheat seedlings were evaluated.Wheat seedlings were cultivated in aqueous solution with [C8 mim]Br at different concentrations (0,1,2,4,6,8 mg/L).The contents of photosynthetic pigment and proline,peroxidation of membrane lipid,and activities of antioxidation enzymes (superoxide dismutase,catalase,peroxidase and ascorbate peroxidase) in leaves were measured on day 7 after treatment with [C8 mim]Br.The results showed that [C8 mim]Br significantly decreased the contents of photosynthetic pigments,activities of antioxidant enzymes in the wheat leaves and in dry weight of seedlings,while increased the proline content and membrane lipid peroxidation.The results suggested that [C8 mim]Br can inhibit photosynthesis and lead to oxidative stress to wheat seedlings. | Ping Liu Yifeng Ding Haiying Liu Liping Sun Xiaoyu Li Jianji Wang | 2010 | Journal of Environmental Sciences2010，22，12： | 6 |
| 17 | Functional regionalization with the restriction of ecological shelter zones: A case of Zhaotong in Yunnan显示文摘生态的躲蔽处地区重建是瞄准到国家,区域和盆的生态的安全的生态系统恢复和保存工程。长江的上面的活动范围的生态的躲蔽处地区的重建成为了西方的发展策略的最重要的任务之一。这篇文章,作为一个例子拿 Zhaotong,学习生态的躲蔽处地区的功能的区域化。学习为其主要任务是环境保留的小、中等的区域的功能的区域化供应一个盒子。与功能的区域化的理论的指导,并且基于 Zhaotong 鈥檚 天赋的分析,生态、社会经济的因素,纸为因素建议五个原则选择。这些原则包括:(1 ) 颠倒顺序评估;(2 ) 选择主要因素;(3 ) 保留镇的行政区域的完全;并且(4 ) 由本地管理使产品可接受。为了分析选择因素,在 2002 的 LUCC 数据, 1:50,000 消除地图和镇单位的空间地位,在 2004 的社会经济的统计数据被使用。RS 和 GIS 工具也被使用融化传统、现代的地理方法。这将对在多山的区域的功能的区域化研究有用。作为一个结论,生态的保存或经济开发的领先的功能的区域分别地被建议。Zhaotong 城市被划分成二水平的功能的区域。第一水平包括三条带功能的区域和他们将带分区的发展中的方向。秒级包括八个分区,它是实现的政策区域,和愿望供应指导到 Zhaotong 鈥檚 生态的躲蔽处地区重建。 | DU Yu WANG Chuansheng ZHAO Haiying YANG Xiaoguang | 2007 | Journal of Geographical Sciences2007，17，3： | 5 |
| 18 | Xeno-repopulation of Fah^(-/-)Nod/Scid mice livers by human hepatocytes显示文摘Functional human hepatocytes xenografted into the liver of mice can be used as a model system to study pharmacokinetics,infection of hepatitis viruses,and the efficacy of hepatitis vaccines.Significant levels of liver xeno-repopulation have been reported in Fah-/-Rag2-/-Il2rg-/-mice.However,the high mortality and low breeding rate of this model may hinder its application.A new model,termed Fah-/-Nod/Scid mice,which combines the advantages of liver repopulation in Fah-/-mice with the ease of xenotransplantation in Nod/Scid mice was obtained by gradual cross-breeding.Fah-/-Nod/Scid mice were easily maintained in breeding colonies and in adult animal care facilities.FK506 treatment combined with gradual withdrawal of NTBC before cell transplantation ensured that Fah-/-Nod/Scid mice were susceptible to liver xeno-repopulation by human hepatocytes;the proportion of engrafted human hepatocytes reached 33.6%.The function of the expanded human hepatocytes within the chimeric liver was confirmed by weight curve analysis,the expression of characteristic proteins,and the biochemical analysis of liver function.These results show that Fah-/-Nod/Scid mice are an ideal humanized liver mouse model with many useful applications. | SU BaoLiang LIU ChangCheng XIANG Dao ZHANG HaiBin YUAN SiMing WANG MinJun CHEN Fei ZHU HaiYing HE ZhiYing WANG Xin HU YiPing | 2011 | Science China(Life Sciences)2011，54，3： | 5 |
| 19 | Production of aryl oxygen-containing compounds by catalytic pyrolysis of bagasse lignin over LaTi0.2Fe0.8O3 prepared by different methods显示文摘To realize the resource and high-value utilization,a new approach,named bagasse lignin(BL) used to produce aryl oxygen-containing compounds by catalytic pyrolysis over perovskite,was proposed,LaTi0.2Fe0.8O3(LTF) samples prepared by the sol-gel method(SG) and the solid-state reaction method(SS)were characterized.The catalytic action on BL pyrolysis was performed by the test of TG-DTG and the evaluation of the fixed bed micro-reactor,the components and contents of the products were determined.The results show that LTF samples have cubic perovskite phase,LTF prepared by SG(LTF-SG) is porous with larger specific surface area than LTF prepared by SS(LTF-SS).During the pyrolysis of BL,the addition of LTF lowers the pyrolysis temperature and the activation energy,the contents of CO2 and CO in gaseous products reduce by 4.6%-8.0% and 30.7%-34.3%,respectively,the total content of aryl oxygencontaining compounds(including phenolics,guaiacols,syringols and phenylates) in liquid products increases from 62 wt% to more than 72 wt%,and LTF-SG shows better catalytic performance.LTF samples have nice phase and catalytic stabilities for BL pyrolysis after five successive redox cycles. | Haiying Wang Hongjing Han Enhao Sun Yanan Zhang Jinxin Li Yanguang Chen Hua Song Hongzhi Zhao Yue Kang | 2020 | Journal of Rare Earths2020，38，1： | 5 |
| 20 | Three-dimensional inversion of borehole-surface electrical data based on quasi-analytical approximation显示文摘地上凿穿表面的 3D 倒置为复杂 geo 电的模型的电的数据仍然是在地球物理的探索的一个挑战性的问题。我们为 3D 倒置开发了一个节目到地上凿穿表面电的数据基于伪分析的近似(质量保证) 并且 re 加权调整结合坡度方法(RRCG ) 用视觉 Fortran 6.5 的算法。到向前当模特儿和 Frechet 衍生物计算的 QA 近似的申请戏剧性地加快计算。为理论模型的合成数据的试用计算证明程序快、高度精确。 | Wang Zhigang He Zhanxiang Liu Haiying | 2006 | Applied Geophysics2006，3，3： | 5 |
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