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| 1 | Development of SSR markers from ESTs of gramineous species and their chromosome location on wheat显示文摘407,663 的一个总数表示了小麦,大麦,玉米,米饭,和蜀黍的顺序标签(EST ) ,从 GenBank/dbEST 获得了,被用来寻找简单顺序重复(SSR ) 。10,253 EST-SSRs 的一个总数,说明了 2.52% 所有 EST,被识别。用教材首相 5.0, 1367 EST-SSR 教材对被设计,哪个 715 与高质量被综合。 715 教材对在五庄稼在一样的 PCR 条件,和有效教材对下面在小麦,米饭,玉米,棉花,和大豆上被测试是 500 (69.93%), 383 (53.57%), 452 (63.22%), 357 (49.93%),并且 388 (56.27%)分别地。这显示了在扩及远距离的种类之间的 EST-SSR 标记的高可转移性。另外,有 240 loci 的 139 EST-SSR 教材对在由使用小麦的中国春天 nulli-tetrasomic 线的所有 21 个小麦染色体上是局部性的。 | Linzhi Li Junjun Wang Ying Guo Fangshan Jiang Yunfeng Xu Yingying Wang Haitao Pan Guanzhu Han Ruijun Li Sishen Li | 2008 | Progress in Natural Science:Materials International2008，18，12： | 25 |
| 2 | The linkage maps of Dendrobium species based on RAPD and SRAP markers显示文摘Dendrobium plants are used commonly as tonic herbs and health food in many Asian countries,especially in China.Here we report the genetic map construction of two Dendrobium species with a double pseudo-testcross strategy using random amplified polymorphic DNA(RAPD) and sequence-related amplified polymorphism(SRAP) markers.A F1 mapping population of 90 individuals was developed from a cross between D.officinale and D.hercoglossum.A total of 307 markers,including 209 RAPD and 98 SRAP,were identified and used for genetic linkage group(LG) analysis.The D.officinale linkage map consisted of 11 major linkage groups and 3 doublets,which covered 629.4 cM by a total of 62 markers with an average locus distance of 11.2 cM between two adjacent markers.The D.hercoglossum linkage map contained 112 markers mapped on 15 major and 4 minor linkage groups,spanning a total length of 1,304.6 cM with an average distance of 11.6 cM between two adjacent markers.The maps constructed in this study covered 92.7% and 82.7% of the D.hercoglossum and D.officinale genomes respectively,providing an important basis for the mapping of horticultural and medicinal traits and for the application of marker-assisted selection in Dendrobium breeding program. | Dawei Xue Shangguo Feng Hongyan Zhao Hua Jiang Bo Shen Nongnong Shi Jiangjie Lu Junjun Liu Huizhong Wang | 2010 | Journal of Genetics and Genomics2010，37，3： | 26 |
| 3 | Exosomes:key players in cancer and potential therapeutic strategy显示文摘Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in intercellular communication.The components of exosomes,including proteins,DNA,mRNA,microRNA,long noncoding RNA,circular RNA,etc.,which play a crucial role in regulating tumor growth,metastasis,and angiogenesis in the process of cancer development,and can be used as a prognostic marker and/or grading basis for tumor patients.Hereby,we mainly summarized as followed:the role of exosome contents in cancer,focusing on proteins and noncoding RNA;the interaction between exosomes and tumor microenvironment;the mechanisms that epithelial-mesenchymal transition,invasion and migration of tumor affected by exosomes;and tumor suppression strategies based on exosomes.Finally,the application potential of exosomes in clinical tumor diagnosis and therapy is prospected,which providing theoretical supports for using exosomes to serve precise tumor treatment in the clinic. | Jie Dai Yangzhou Su Suye Zhong Li Cong Bang Liu Junjun Yang Yongguang Tao Zuping He Chao Chen Yiqun Jiang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 8 |
| 4 | Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic liver transplantation显示文摘Understanding the effect of immunosuppressive agents on intestinal microbiota is important to reduce the mortality and morbidity from orthotopic liver transplantation (OLT). We investigated the relationship between the commonly used immunosuppressive agent cyclosporine A (CSA) and the intestinal microbial variation in an OLT model. The rat samples were divided as follows:(1) N group (normal control);(2) I group (isograft LT, Brown Norway [BN] rat to BN);(3) R group (allograft LT, Lewis to BN rat);and (4) CSA group (R group treated with CSA). The intestinal microbiota was assayed by denaturing gradient gel electrophoresis profiles and by using real-time polymerase chain reaction. The liver histopathology and the alanine/aspartate aminotransferase ratio after LT were both ameliorated by CSA. In the CSA group, the numbers of rDNA gene copies of Clostridium cluster I, Clostridium cluster XIV, and Enterobacteriaceae decreased, whereas those of Faecalibacterium prausnitzii increased compared with the R group. Cluster analysis indicated that the samples from the N, I, and CSA groups were clustered, whereas the other clusters contained the samples from the R group. Hence, CSA ameliorates hepatic graft injury and partially restores gut microbiota following LT, and these may benefit hepatic graft rejection. | Junjun Jia Xinyao Tian Jianwen Jiang Zhigang Ren Haifeng Lu Ning He Haiyang Xie Lin Zhou Shusen Zheng | 2019 | Frontiers of Medicine2019，13，4： | 5 |
| 5 | Modeling heterogeneous chemical processes on aerosol surface显示文摘To explore the possible impact of heterogeneous chemical processes on atmospheric trace components,a coupled box model including gas-phase chemical processes,aerosol thermodynamic equilibrium processes,and heterogeneous chemical processes on the surface of dust,black carbon(BC) and sea salt is set up to simulate the effects of heterogeneous chemistry on the aerosol surface,and analyze the primary factors affecting the heterogeneous processes.Results indicate that heterogeneous chemical processes on the aerosol surface in the atmosphere will affect the concentrations of trace gases such as H2O2,HO2,O3,NO2,NO3,HNO3 and SO2,and aerosols such as SO42-,NO3- and NH4+.Sensitivity tests suggest that the magnitude of the impact of heterogeneous processes strongly depends on aerosol concentration and the surface uptake coefficients used in the box model.However,the impact of temperature on heterogeneous chemical processes is considerably less.The 'renoxification' of HNO3 will affect the components of the troposphere such as nitrogen oxide and ozone. | Junjun Deng Tijian Wang Li Liu Fei Jiang | 2010 | Particuology2010，8，4： | 4 |
| 6 | Influence of the quickness and duration of De Qi on the analgesic effect of acupuncture in primary dysmenorrhea patients with a cold and dampness stagnation pattern显示文摘OBJECTIVE: To investigate the influence of the quickness and duration of De Qi(or Qi arrival) on the analgesic effect of acupuncture in primary dysmenorrhea patients with a cold and dampness stagnation pattern.METHODS: Sixty-eight patients were randomly assigned to the De Qi group(deep needling with thick needles and manipulation, n = 17) or the non-De Qi group(shallow needling with thin needles and no manipulation, n = 51). Both groups underwent needling at Sanyinjiao(SP 6) for 30 min.The visual analogue scale was used to measure the degree of menstrual pain, and the Acupuncture De Qi Clinical Assessment Scale was used to assess De Qi. Only data from patients who experienced actual De Qi were included in the analysis.RESULTS: Thirty-nine patients experienced actual De Qi. Patients who experienced actual De Qi in the De Qi group(n = 14) felt De Qi more rapidly(P =0.028) and for a longer duration(P = 0.04) than patients who experienced actual De Qi in the non-De Qi group(n = 25). Both groups showed a reduction in the visual analogue scale score for pain after treatment. The analgesic effect did not significantly differ between the two groups. The occurrence time of De Qi showed a significant negative correlation with pain reduction at 20 and 30 min after needle removal(P < 0.05). There was no correlation between the duration of De Qi and the therapeutic effect.CONCLUSION: In primary dysmenorrhea patients with a cold and dampness stagnation pattern,quicker onset of De Qi when needling Sanyinjiao(SP 6) achieves a better analgesic outcome. However, a longer duration of De Qi does not affect the degree of analgesia. Compared with minimal acupuncture, active acupuncture stimulation achieves a more rapid onset and longer duration of De Qi. | Hu Nijuan Ma Liangxiao Wang Pei Wu Guiwen Zhao Minyi Hu Shangqing Sun Junjun Wang Yafeng Zhang Zhuang Zhu Jiang | 2019 | Journal of Traditional Chinese Medicine2019，39，2： | 4 |
| 7 | Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication显示文摘Bicyclol is a synthetic drug for hepatoprotection in clinic since 2004. Preliminary clinical observations suggest that bicyclol might be active against hepatitis C virus(HCV) with unknown mechanism. Here, we showed that bicyclol significantly inhibited HCV replication in vitro and in hepatitis C patients. Using bicyclol as a probe, we identified glycolipid transfer protein(GLTP) to be a novel restrictive factor for HCV replication. The GLTP preferentially bound host vesicle-associated membrane protein-associated protein-A(VAP-A) in competition with the HCV NS5 A, causing an interruption of the complex formation between VAP-A and HCV NS5 A. As the formation of VAP-A/NS5 A complex is essential for viral RNA replication, up-regulation of GLTP by bicyclol reduced the level of VAP-A/NS5 A complex and thus inhibited HCV replication. Bicyclol also exhibited an inhibition on HCV variants resistant to direct-acting antiviral agents(DAAs) with an efficacy identical to that on wild type HCV. In combination with bicyclol, DAAs inhibited HCV replication in a synergistic fashion. GLTP appears to be a newly discovered host restrictive factor for HCV replication, Up-regulation of GLTP causes spontaneous restriction of HCV replication. | Meng-Hao Huang Hu Li Rong Xue Jianrui Li Lihua Wang Junjun Cheng Zhouyi Wu Wenjing Li Jinhua Chen Xiaoqin Lv Qiang Li Pei Lan Limin Zhao Yongfeng Yang Zonggen Peng Jiandong Jiang | 2019 | Acta Pharmaceutica Sinica B2019，9，4： | 3 |
| 8 | Chemical Synthesis Residual Pyrolysis and Combustion: Kinetics and Evolved Gases Investigated by TG-FTIR显示文摘Chemical synthetic residual is one of the solid wastes generated from pharmaceutical industry.The pyrolysis and combustion characteristics of chemical synthesis residual were investigated using a thermogravimetric analyser coupled with Fourier transform infrared spectroscopy(TG-FTIR)in this study.The processes of pyrolysis and combustion can be divided into three stages.The average weight loss rate of pyrolysis process at low temperature was higher than that of combustion.The kinetic parameters of chemical synthesis residual during pyrolysis and combustion were calculated based on the TG results.Acetic acid and 4-aminophenol were the main evolved matter observed in the pyrolysis process.The emission characteristics of combustion at low temperature were similar to that of the pyrolysis,while CO2 was found as the major gaseous product at high temperature.A high temperature about 850°C is needed to make sure the complete combustion of chemical synthesis residual. | FANG Chunqi JIANG Xuguang LV Guojun YAN Jianhua LIN Xuliang SONG Huibo CAO Junjun | 2020 | Journal of Thermal Science2020，29，1： | 3 |
| 9 | Loop Closure Detection With Reweighting Net VLAD and Local Motion and Structure Consensus显示文摘Dear Editor,Loop closure detection(LCD)is an important module in simultaneous localization and mapping(SLAM).In this letter,we address the LCD task from the semantic aspect to the geometric one.To this end,a network termed as AttentionNetVLAD which can simultaneously extract global and local features is proposed.It leverages attentive selection for local features,coupling with reweighting the soft assignment in NetVLAD via the attention map for global features.Given a query image,candidate frames are first identified coarsely by retrieving similar global features in the database via hierarchical navigable small world(HNSW).As global features mainly summarize the semantic information of images and lead to compact representation,information about spatial arrangement of visual elements is lost. | Kaining Zhang Jiayi Ma Junjun Jiang | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，6： | 2 |
| 10 | ALYREF mediates RNA m^(5)C modification to promote hepatocellular carcinoma progression显示文摘Dear Editor,The incidence of hepatocellular carcinoma(HCC)is increasing in many countries due to hepatic virus infection and unhealthy diet habits,and the unsatisfactory overall survival rate calls for novel treatments with higher efficacy.1 Recent studies have shown that RNA modifications are likely to participate in the progression of HCC,2 suggesting new methods for tumor growth control.Specifically,5-methylcytosine(m5C)is one of the most interesting RNA modification types,as accumulating evidence suggests its role in the promotion of HCC tumorigenesis.3 The RNA methyltransferase Aly/REF export factor(ALYREF)is considered one type of“reader”protein located in the nucleus that recognizes and binds directly with m5C sites in RNA and facilitates the export of RNA from the nucleus to the cytoplasm.4 Notably,ALYREF is considered a promising target for diagnosis and prognosis prediction.5 However,until now,the low number of related studies has limited the understanding of the mechanism of the HCC-promoting effects of ALYREF. | Chen Xue Xinyu Gu Qiuxian Zheng Qingmiao Shi Xin Yuan Yuanshuai Su Junjun Jia Jianwen Jiang Juan Lu Lanjuan Li | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 2 |
| 11 | Characterizing the human mobility pattern in a large street network显示文摘 | JIANG Bin YIN Junjun ZHAO Sijian | 2009 | Physical Review E2009，80，02： | 1 |
| 12 | Characterization of visibility and its affecting factors over Nanjing, China显示文摘 | Junjun Deng Tijian Wang Ziqiang Jiang Min Xie Renjian Zhang Xiaoxian Huang Jialei Zhu | 2011 | Atmospheric Research2011，，3： | 1 |
| 13 | Systematic analysis of clinical relevance and molecular characterization of m^(6)A in COVID-19 patients显示文摘N6-methyladenosine(m6A)is the most prevalent post-transcriptional RNA modification in mRNA and long non-coding RNAs of eukaryotes,and its biological functions are mediated by m6A writers,erasers and readers.1 A nuclear methyltransferase complex consisting of METTL3,METTL14,WTAP,VIRMA,ZC3H13,RBM15(or RBM15B),YWHAG,TRA2A and CAPRIN1 catalyzes the m6A modifications,acting as m6A writers.1 m6A demethylase ALKBH5 as well as m6A demethylase FTO mediate the demethylation of m6As,acting as the m6A erasers. | Sanqi An Zhouhua Xie Yanyan Liao Junjun Jiang Wenyi Dong Fuqiang Yin Wen-Xing Li Li Ye Jianyan Lin Hao Liang | 2022 | Genes & Diseases2022，9，5： | 1 |
| 14 | Urban air quality and regional haze weather forecast for Yangtze River Delta region 显示文摘 | WANG Tijian JIANG Fei DENG Junjun | 2012 | Atmospheric Environment2012，58，： | 1 |
| 15 | Photonic drop splitters based on self-collimation ring resonators in a silicon photonic crystal显示文摘 | Junjun Li Xiyao Chen Zexuan Qiang Junzhen Jiang Guimin Lin Xiaofu Xu Hui Li Yishen Qiu | 2011 | Optics Communications2011，，24： | 1 |
| 16 | Higher numbers of T-bet + intratumoral lymphoid cells correlate with better survival in gastric cancer显示文摘 | Lu-jun Chen Xiao Zheng Yue-ping Shen Yi-bei Zhu Qing Li Junjun Chen Rui Xia Shu-ming Zhou Chang-ping Wu Xue-guang Zhang Bin-feng Lu Jing-ting Jiang | 2013 | Cancer Immunology Immunotherapy2013，，3： | 1 |
| 17 | Self-organized natural roads for predicting traffic flow: a sensitivity study显示文摘 | Bin Jiang Sijian Zhao Junjun Yin | 2008 | Journal of Statistical Mechanics: Theory and Expe2008，，07： | 1 |
| 18 | Formation and stability of G-quadruplexes self-assembled from Guaninerich strands显示文摘 | Zhou Jiang Yuan Gu Liu Junjun | 2007 | Chem Eur J2007，13，： | 1 |
| 19 | Super-Resolution for Face Image with an Improved K-NN Search Strategy显示文摘Recently, neighbor embedding based face super-resolution(SR) methods have shown the ability for achieving high-quality face images, those methods are based on the assumption that the same neighborhoods are preserved in both low-resolution(LR) training set and high-resolution(HR) training set. However, due to the 'one-to-many' mapping between the LR image and HR ones in practice, the neighborhood relationship of the LR patch in LR space is quite different with that of the HR counterpart, that is to say the neighborhood relationship obtained is not true. In this paper, we explore a novel and effective re-identified K-nearest neighbor(RIKNN) method to search neighbors of LR patch. Compared with other methods, our method uses the geometrical information of LR manifold and HR manifold simultaneously. In particular, it searches K-NN of LR patch in the LR space and refines the searching results by re-identifying in the HR space, thus giving rise to accurate K-NN and improved performance. A statistical analysis of the influence of the training set size and nearest neighbor number is given, experimental results on some public face databases show the superiority of our proposed scheme over state-of-the-art face hallucination approaches in terms of subjective and objective results as well as computational complexity. | QU Shenming HU Ruimin CHEN Shihong JIANG Junjun WANG Zhongyuan ZHANG Maosheng | 2016 | China Communications2016，13，4： | 1 |
| 20 | Self-organized Natural Roads for Predicting Traffic Flow:A Sensitivity Study显示文摘 | Jiang Bin Zhao Sijian Yin Junjun | 2008 | Journal of Statistical Mechanics:Theory and Experiment2008，，7： | 1 |
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