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| 1 | Diclofop-methyl affects microbial rhizosphere community and induces systemic acquired resistance in rice显示文摘Diclofop-methyl(DM),a widely used herbicide in food crops,may partly contaminate the soil surface of natural ecosystems in agricultural area and exert toxic effects at low dose to nontarget plants.Even though rhizosphere microorganisms strongly interact with root cells,little is known regarding their potential modulating effect on herbicide toxicity in plants.Here we exposed rice seedlings(Xiushui 63) to 100 μg/L DM for 2 to 8 days and studied the effects of DM on rice rhizosphere microorganisms,rice systemic acquired resistance(SAR) and rice-microorganisms interactions.The results of metagenomic 16 S rDNA Illumina tags show that DM increases bacterial biomass and affects their community structure in the rice rhizosphere.After DM treatment,the relative abundance of the bacterium genera Massilia and Anderseniella increased the most relative to the control.In parallel,malate and oxalate exudation by rice roots increased,potentially acting as a carbon source for several rhizosphere bacteria.Transcriptomic analyses suggest that DM induced SAR in rice seedlings through the salicylic acid(but not the jasmonic acid) signal pathway.This response to DM stress conferred resistance to infection by a pathogenic bacterium,but was not influenced by the presence of bacteria in the rhizosphere since SAR transcripts did not change significantly in xenic and axenic plant roots exposed to DM.The present study provides new insights on the response of rice and its associated microorganisms to DM stress. | Si Chen Xingxing Li Michel Lavoie Yujian Jin Jiahui Xu Zhengwei Fu Haifeng Qian | 2017 | Journal of Environmental Sciences2017，29，1： | 8 |
| 2 | Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of MAPKKK18 in Arabidopsis显示文摘Hydrogen sulfide(H2S)is a signaling molecule that regulates plant hormone and stress responses.The phytohormone abscisic acid(ABA)plays an important role in plant adaptation to unfavorable environmental conditions and induces the persulfidation of L-CYSTEINE DESULFHYDRASE1(DES1)and the production of H2S in guard cells.However,it remains largely unclear how H2S and protein persulfidation participate in the relay of ABA signals.In this study,we discovered that ABSCISIC ACID INSENSITIVE 4(ABI4)acts downstream of DES1 in the control of ABA responses in Arabidopsis.ABI4 undergoes persulfidation at Cys250 that is triggered in a time-dependent manner by ABA,and loss of DES1 function impairs this process.Cys250 and its persulfidation are essential for ABI4 function in the regulation of plant responses to ABA and the H2S donor NaHS during germination,seedling establishment,and stomatal closure,which are abolished in the ABI4Cys250Ala mutated variant.Introduction of the ABI4Cys250Ala variant into the abi4 des1 mutant did not rescue its hyposensitivity to ABA.Cys250 is critical for the binding of ABI4 to its cognate motif in the promoter of Mitogen-Activated Protein Kinase Kinase Kinase 18(MAPKKK18),which propagates the MAPK signaling cascade induced by ABA.Furthermore,the DES1-mediated persulfidation of ABI4 enhances the transactivation activity of ABI4 toward MAPKKK18,and ABI4 can bind the DES1 promoter,forming a regulatory loop.Taken together,these findings advance our understanding of a post-translational regulatory mechanism and suggest that ABI4 functions as an integrator of ABA and MAPK signals through a process in which DES1-produced H2S persulfidates ABI4 at Cys250. | Mingjian Zhou Jing Zhang Jie Shen Heng Zhou Didi Zhao Cecilia Gotor Luis CRomero Ling Fu Zongmin Li Jing Yang Wenbiao Shen Xingxing Yuan Yanjie Xie | 2021 | Molecular Plant2021，14，6： | 5 |
| 3 | GaN-based substrates and optoelectronic materials and devices显示文摘In order to solve the problems of GaN heteroepitaxy on sapphire substrate,some techniques were explored.Freestanding GaN substrates have been made by hydride vapor phase epitaxy(HVPE),laser lift-off(LLO),and chemical mechanical polishing techniques.Wafer bending and cracking in the HVPE growth were partly settled by pulsed flow modulation method.High-crystal quality was established for 1.2 mm thick GaN substrate by X-ray diffraction measurement,in which the full width of half maximum values were 72,110 arcsec for(102),(002)peaks.A novel micro-size patterned sapphire substrate(PSS)and a nano PSS were also fabricated.High-power vertical structure light emitting diodes(VSLEDs)have been developed by Au–Sn eutectic wafer bonding,homemade micro-area LLO,and light extraction structure preparation.The high-injection-level active region with low temperature GaN sandwiched layers was used for lowefficiency droop.The light output power of VSLED was achieved as 400 mW driven at 350 mA,and the dominant wavelength is about 460 nm.The structures and properties of strain modulated superlattices(SLs)and quantum wells as well as advanced simulation of carriers transport across the electron blocking layer were investigated in laser diodes.The hole concentration was achieved as high as1.6 9 1018cm-3in AlGaN/GaN SLs:Mg by inserting an AlN layer.High-quality AlGaN epilayers and structures were grown by MOCVD.Some device structures of UV LEDs and detectors were demonstrated.The emission wavelength of 262 nm UV LED has been successfully fabricated.At last,high-quality InN and InGaN materials for solar cell were grown by boundary-temperature-controlled epitaxy and growth-temperature-controlled epitaxy.Hall-effect measurement showed a recorded electron mobility of 3,280 cm2/(V s)and a residual electron concentration of 1.47 9 1017cm-3at 300 K. | Guoyi Zhang Bo Shen Zhizhong Chen Xiaodong Hu Zhixin Qin Xinqiang Wang Jiejun Wu Tongjun Yu Xiangning Kang Xingxing Fu Wei Yang Zhijian Yang Zhizhao Gan | 2014 | Chinese Science Bulletin2014，59，12： | 4 |
| 4 | Highly Reversible Li–Se Batteries with Ultra-Lightweight N,S-Codoped Graphene Blocking Layer显示文摘The desire for practical utilization of rechargeable lithium batteries with high energy density has motivated attempts to develop new electrode materials and battery systems. Here, without additional binders we present a simple vacuum filtration method to synthesize nitrogen and sulfur codoped graphene(N,S-G) blocking layer, which is ultra-lightweight, conductive, and free standing. When the N,S-G membrane was inserted between the catholyte and separator, the lithium–selenium(Li–Se)batteries exhibited a high reversible discharge capacity of 330.7 mAh g^(-1) at 1 C(1 C = 675 mA g^(-1)) after 500 cycles and high rate performance(over 310 mAh g^(-1) at 4 C) even at an active material loading as high as ~5 mg cm^(-2). This excellent performance can be ascribed to homogenous dispersion of the liquid active material in the electrode, good Li^+-ion conductivity, fast electronic transport in the conductive graphene framework, andstrong chemical confinement of polyselenides by nitrogen and sulfur atoms. More importantly, it is a promising strategy for enhancing the energy density of Li–Se batteries by using the catholyte with a lightweight heteroatom doping carbon matrix. | Xingxing Gu Lingbao Xin Yang Li Fan Dong Min Fu Yanglong Hou | 2018 | Nano-Micro Letters2018，10，4： | 4 |
| 5 | Polymorphism of human cytomegalovirus(HCMV) UL144 gene in low passage clinical isolates显示文摘To explore the impact of gene polymorphism of human cytomegalovirus(HCMV)on virus virulence,the full-length UL144 gene and partial sequence of glycoprotein B(UL55)gene were sequenced and analyzed for 23clinical strains of HCMV isolated from urine samples of pediatric patients with congenital or postnatal HCMV infection.Among the 23 isolates,13(57%)were UL144genotype 1A,3(13%)were UL144 genotypes 2 and 7(30%)were UL144 genotype 3;geographic differences in genotype distribution were found for both UL144 and gB gene.No UL144 genotypes 1B and 1C were found in this study while these two genotypes were common in HCMV strains isolated in the US.Our results also demonstrated that for all clinical strains of gB genotypes I,III and UL144genotypes 1A,2,and 3 found in this study,mother-to-fetus vertical transmission was possible. | Xingxing Fu Liping Li Chaoyang Huang Xiaoman Li Huadong Wang Zhenyuan Xie Ze Chen | 2014 | Chinese Science Bulletin2014，59，25： | 3 |
| 6 | Rice GLUTATHIONE PEROXIDASE1-mediated oxidation of bZIP68 positively regulates ABA-independent osmotic stress signaling显示文摘Osmotic stress caused by drought and high salinity is a significant environmental threat that limits plant growth and agricultural yield. Redox regulation plays an important role in plant stress responses, but the mechanisms by which plants perceive and transduce redox signals are still underexplored. Here, we report a critical function for the thiol peroxidase GPX1 in osmotic stress response in rice, where it serves as a redox sensor and transducer. GPX1 is quickly oxidized upon exposure to osmotic stress and forms an intramolecular disulfide bond, which is required for the activation of bZIP68, a VRE-like basic leucine zipper (bZIP) transcription factor involved in the ABA-independent osmotic stress response pathway. The disulfide exchange between GPX1 and bZIP68 induces homo-tetramerization of bZIP68 and thus positively regulates osmotic stress response by regulating osmotic-responsive gene expression. Furthermore, we discovered that the nuclear translocation of GPX1 is regulated by its acetylation under osmotic stress. Taken together, our findings not only uncover the redox regulation of the GPX1-bZIP68 module during osmotic stress but also highlight the coordination of protein acetylation and redox signaling in plant osmotic stress responses. | Heng Zhou Feng Zhang Fengchao Zhai Ye Su Ying Zhou Zhenglin Ge Priyadarshini Tilak Jürgen Eirich Iris Finkemeier Ling Fu Zongmin Li Jing Yang Wenbiao Shen Xingxing Yuan Yanjie Xie | 2022 | Molecular Plant2022，15，4： | 2 |
| 7 | Lattice constant effects of photonic crystals on the extraction of guided mode of GaN based light emitting diodes显示文摘We have fabricated a series of square-lattice hole photonic crystal (2PhC) arrays simultaneously at the un-current injection region on a special sample of GaN based light emitting diode (LED) by using focus ion beam milling (FIBM). The lattice constants of the 2PhC arrays vary from 230 to 1500 nm,while the 2PhC arrays have a constant area of about 9 μm×18 μm and a fixed depth of 150±10 nm which approaches but does not penetrate the active layer. Microscopic electroluminescence images and spectral measurements consistently confirm that the top emitting intensities from different 2PhCs are all enhanced compared with the unpatterned region. It is demonstrated that the output coupling of propagating guided modes is realized by the diffracted transmission of the 2PhCs. The enhancement factors of the guided modes compared with the unpatterned region are plotted as function of the lattice constant. It is found that the highest enhancements for the extraction of guided modes were obtained for the lattice constant of 230 and 460 nm of 2PhCs. The results are discussed by the two-dimensional rigorous coupled wave analysis (RCWA). | FU XingXing ZHANG Bei KANG XiangNing XU Jun XIONG Chang ZHANG GuoYi | 2011 | Science China(Technological Sciences)2011，54，1： | 2 |
| 8 | A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1βand IL-6显示文摘Glycolytic metabolism enzymes have been implicated in the immunometabolism field through changes in metabolic status. PGK1 is a catalytic enzyme in the glycolytic pathway. Here, we set up a high-throughput screen platform to identify PGK1 inhibitors. DC-PGKI is an ATPcompetitive inhibitor of PGK1 with an affinity of Kd= 99.08 nmol/L. DC-PGKI stabilizes PGK1in vitro and in vivo, and suppresses both glycolytic activity and the kinase function of PGK1. In addition,DC-PGKI unveils that PGK1 regulates production of IL-1β and IL-6 in LPS-stimulated macrophages.Mechanistically, inhibition of PGK1 with DC-PGKI results in NRF2(nuclear factor-erythroid factor 2-related factor 2, NFE2L2) accumulation, then NRF2 translocates to the nucleus and binds to the proximity region of Il-1β and Il-6 genes, and inhibits LPS-induced expression of these genes. DC-PGKI ameliorates colitis in the dextran sulfate sodium(DSS)-induced colitis mouse model. These data support PGK1 as a regulator of macrophages and suggest potential utility of PGK1 inhibitors in the treatment of inflammatory bowel disease. | Liping Liao Wenzhen Dang Tingting Lin Jinghua Yu Tonghai Liu Wen Li Senhao Xiao Lei Feng Jing Huang Rong Fu Jiacheng Li Liping Liu Mingchen Wang Hongru Tao Hualiang Jiang Kaixian Chen Xingxing Diao Bing Zhou Xiaoyan Shen Cheng Luo | 2022 | Acta Pharmaceutica Sinica B2022，12，11： | 2 |
| 9 | High-speed optical secure communication with an external noise source and an internal time-delayed feedback loop显示文摘We propose and experimentally demonstrate a novel physical layer encryption scheme for high-speed optical communication. A 10 Gb/s on-off keying signal is secretly transmitted over 100 km standard single-mode fiber.The intensity-modulated message is secured by the encryption mechanism, which is composed of an external noise source and an internal time-delayed feedback loop. The external noise serves as an entropy source with sufficient randomness. The feedback loop structure in the transmitter introduces a time-domain encryption key space, and a corresponding open-loop configuration at the receiver side is used for synchronization and decryption.Experiment results show the effectiveness of the proposed scheme. For a legitimate terminal, bit error rate below10-8 can be obtained. Decryption degradations with the mismatch of different hardware parameters are researched. The time delay in the feedback loop provides a sensitive encryption key. For other hardware parameters,the system is robust enough for synchronization. Meanwhile, the time-delay signature of the loop is able to be well concealed by the external noise. Moreover, the proposed scheme can support density wavelength division multiplexing transmission with a relatively simple structure. This work also provides a new concept to establish optical secure communication by combining a time-delayed feedback chaotic system and random noise. | YUDI FU MENGFAN CHENG XINGXING JIANG QUAN YU LINBOJIE HUANG LEI DENG DEMING LIU | 2019 | Photonics Research2019，7，11： | 2 |
| 10 | Melt grafting of maleic anhydride onto polypropylene with assistance of a- methylstyrene显示文摘 | Luo Weihua Liu Xingxing Fu Yujuan | 2012 | Polymer Engineering and Science2012，52，4： | 1 |
| 11 | Nitrogen‐Doped Carbon Encapsulated Mesoporous Vanadium Nitride Nanowires as Self‐Supported Electrodes for Flexible All‐Solid‐State Supercapacitors显示文摘 | Biao Gao Xingxing Li Xiaolin Guo Xuming Zhang Xiang Peng Lei Wang Jijiang Fu Paul K. Chu Kaifu Huo | 2015 | Adv. Mater. Interfaces2015，，13： | 1 |
| 12 | Halogen modified two-dimensional covalent triazine frameworks as visible-light driven photocatalysts for overall water splitting显示文摘The covalent triazine framework CTF-1 as a member of the two-dimensional covalent organic frameworks(COFs)is a category of novel metal-free photocatalysts for water splitting.The large band gap severely restricts its energy conversion efficiency.By means of the first-principles calculations,we proposed the decoration of CTF-1 by anchoring halogen atoms onto benzene moieties for improving the solar-to-hydrogen(STH)efficiency.The electronic structures reveal that the halogen substitution successfully decreases the band gap of CTF-1.Meanwhile,the calculated free energy changes along the reaction pathway indicate that all these COFs can spontaneously drive overall water splitting under light irradiation in a specific acid-base environment.The time-dependent ab initio non-adiabatic molecular dynamics simulations suggest that the electron-hole recombination periods of these COFs fall in a few to tens of nanoseconds.Excitingly,CTF-1 modified by linking six iodine atoms onto the benzene ring in the para-position(CTF-1-6I)shows a quite low band gap of 2.81 eV,indicating that it is a visible-light driven COF for overall photocatalytic water splitting.Correspondingly,CTF-1-6I also exhibits an extraordinarily promising STH efficiency of 3.70%,which is an order magnitude higher than that of the pristine CTF-1. | Cen-Feng Fu Chuanyu Zhao Qijing Zheng Xingxing Li Jin Zhao Jinlong Yang | 2020 | Science China Chemistry2020，63，8： | 1 |
| 13 | Lattice-parameter effects on diffracted transmission of GaN two-dimensional square-lattice photonic crystals显示文摘The lattice-parameter effects on the diffracted transmission of GaN square-lattice photonic crystals (2PhC) at the wavelength of 460 nm were studied by using a rigorous coupled wave analysis (RCWA). The impacts of lattice parameters on the diffracted transmission are calculated in the ranges for lattice pitch from 100 nm to 2000 nm,fill factor from 0.1 to 0.9 and grating height from 100 nm to 1000 nm,respectively. Our simulation results confirm that the lattice pitch is the dominant factor of the diffraction. It determines how many orders of diffraction occur by the 2PhCs. The larger the lattice pitch,the higher the diffraction orders come into play. Moreover,besides the first-order Bragg diffraction,higher diffraction orders from large pitches of PhCs are also beneficial to the light extraction improvement. The higher enhancement factors of the integrated transmission were obtained from a wide range of pitches with micro-scale GaN 2PhCs. Three different diffraction mechanisms through wave vector analysis were used to discuss the simulation results. | XIONG Chang ZHANG Bei KANG XiangNing FU XingXing ZHANG GuoYi | 2011 | Science China(Technological Sciences)2011，54，1： | 1 |
| 14 | Mechanical properties of dredged soil reinforced by xanthan gum and fibers显示文摘Biopolymers have become popular in geotechnical engineering as they provide a carbon-neutral alternative for soil solidification.Xanthan gum(XG)and jute fiber(JF)were selected to solidify the Yellow River dredged soil.The mechanical behavior of solidified dredged soil(SDS)was investigated using a series of uniaxial compression and splitting tension tests at different XG and JF contents and fiber lengths.The results indicate that on the 28th day,the unconfined compressive strength(UCS)values of SDS samples reached 2.83 MPa and splitting tensile strength(STS)of 0.763 MPa at an XG content of 1.5%.When the JF content was greater than 0.9%,the STS of the SDS samples decreased.This is because that the large fiber content weakened the cementation ability of XG.The addition of JF can significantly increase the strain at peak strength of SDS samples.There is a linear relationship between the UCS and STS of the dredged soils solidified by XG and JF.Microanalysis shows that the strength of SDS samples was improved mainly via the cementation of XG itself and the network structure formed by JF with soil particles.The dredged soil reinforced by XG and JF shows better mechanical performance and has great potential for application. | Dianzhi Feng Bing Liang Xingxing He Fu Yi Jianfei Xue Yong Wan Qiang Xue | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，8： | 0 |
| 15 | Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp.c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1a/XBP-1s axis and JNK signaling显示文摘Lipotoxicity is a pivotal factor that initiates and exacerbates liver injury and is involved in the development of metabolic-associated fatty liver disease(MAFLD).However,there are few reported lipotoxicity inhibitors.Here,we identified a natural anti-lipotoxicity candidate,HN-001,from the marine fungus Aspergillus sp.C1.HN-001 dose-and time-dependently reversed palmitic acid(PA)-induced hepatocyte death.This protection was associated with IRE-1a-mediated XBP-1 splicing inhibition,which resulted in suppression of XBP-1s nuclear translocation and transcriptional regulation.Knockdown of XBP-1s attenuated lipotoxicity,but no additional ameliorative effect of HN-001 on lipotoxicity was observed in XBP-1s knockdown hepatocytes.Notably,the ER stress and lipotoxicity amelioration was associated with PLA2.Both HN-001 and the PLA2 inhibitor MAFP inhibited PLA2 activity,reduced lysophosphatidylcholine(LPC)level,subsequently ameliorated lipotoxicity.In contrast,overexpression of PLA2 caused exacerbation of lipotoxicity and weakened the anti-lipotoxic effects of HN-001.Additionally,HN-001 treatment suppressed the downstream pro-apoptotic JNK pathway.In vivo,chronic administration of HN-001(i.p.)in mice alleviated all manifestations of MAFLD,including hepatic steatosis,liver injury,inflammation,and fibrogenesis.These effects were correlated with PLA2/IRE-1a/XBP-1s axis and JNK signaling suppression.These data indicate that HN-001 has therapeutic potential for MAFLD because it suppresses lipotoxicity,and provide a natural structural basis for developing anti-MAFLD candidates. | Yong Rao Rui Su Chenyan Wu Xingxing Chai Jinjian Li Guanyu Yang Junjie Wu Tingting Fu Zhongping Jiang Zhikai Guo Congjun Xu Ling Huang | 2024 | Acta Pharmaceutica Sinica B2024，14，1： | 0 |
| 16 | S-triggered Schmidt-type rearrangement of vinyl azides to access N-aryl-(trifluoromethylsulfinyl) acetamides显示文摘A novel S-induced Schmidt-type rearrangement of vinyl azides with CF_(3)SO_(2) Na is reported,which is mediated by triphosgene(BTC)under mild reaction conditions.A wide range of N-arylated 2-(trifluoro-methylsulfinyl)acetamides,for the first time,were successfully obtained in good yields,through sequential trifluoromethylsulfinylation and aryl 1,2-migration. | Zhenhua Liu Tian Yu Longhua Li Wei Fu Xingxing Gan Huimin Chen Wen Gao Bo Tang | 2022 | Organic Chemistry Frontiers2022，9，5： | 0 |
| 17 | The Long-Term Impacts of COVID-19 on Physical and Psychological Health—Beijing Municipality,China,December 2022–April 2023显示文摘Summary What is already known about this topic?Reports detailing the clinical presentation of coronavirus disease 2019(COVID-19)are extensive in China.However,data remains limited regarding the long-term effects of the 2022 outbreak on the community and healthcare workers(HCWs).What is added by this report?In the follow-up study conducted with 1,069 community members and 3,309 HCWs infected with COVID-19,we observed that five months postoutbreak,39.2%of community members and 28.7%of HCWs reported experiencing at least one symptom.The symptoms most frequently reported included fatigue or muscle weakness,insomnia,cognitive dysfunction,hair loss,joint or muscle pain,and persistent cough.HCWs tended to experience fewer long-term physical consequences and their symptoms had an expedited recovery time compared to the community members.Nevertheless,HCWs displayed a higher prevalence of moderate to severe depression and anxiety. | Tian Tian Chuan Yang Xiaoyu Long Fei Kong Yu Fu Fang Liu Ling Tuo Xiujun Guo Lei Li Xingxing Zhao Qun Wang Guangti Yuan Huiqing Wang Yuanyuan Wang Jie Qiao | 2023 | China CDC weekly2023，5，40： | 0 |
| 18 | Exploring the psychological impact of the 2022 SARS-CoV-2 Omicron variant outbreak in China显示文摘To the editor:The impact of the coronavirus disease 2019(COVID-19)pandemic in 2020 on mental health was substantialin Chinai2and various other countries.34 Beyond the direct consequences of COVID-19,the pandemic created an environment in which many determinants of mental health were affected.Issues associated with the pandemic,such as loss of livelihood,limited access to medical services,reduced social interactions,and economic downturn,could potentially have adverse effects on the population's mental well-being.5 In November 2021,the World Health Organization(WHO)designated the new variant of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),variant B.1.1.529,as a variant of concern and named it Omicron;its rapid mutation and spread raised a new global health concern. | Gangbin Han Guirong Cheng Feifei Hu Chunli Li Dan Liu Juan Zhou Jing Liu Linya Huang Xiaochang Liu Qianqian Nie Dan Song Deyang Zeng Lang Xu Jinquan Li Yushan Chen Zhen Wei Qiong Wu Xiaoming He Qingming Wu Wei Tan Yufei Mei Xingxing Chen Yangming Ou Jingjing ZhangYafu Yu Mengliu Yang Pengfei Lian Fukai Zhou Renjia Fan Hong Wan Chenlu Hu Yidi Fu Shiyue Li Junyi Wang Cheng Cai Mengdie Pei Yuyang Cui Wanying Cai Yiqing Li Shiyao Pan Chang Chen Yan He Zhaoxia Wu Liu Hu Liang Tao Hongyan Xiao Xinyan Xie Yan Zeng | 2023 | General Psychiatry2023，36，6： | 0 |
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