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| 1 | Clostridium difficile causing acute renal failure: Case presentation and review显示文摘AIM: Clostridium difficile infection is primarily a nosocomial infection but asymptomatic carriers of Clostridium difficile can be found in up to 5% of the general population.Ampicillin, cephalosporins and clindamycin are the antibiotics that are most frequently associated with Clostridium difficile-associated diarrhea or colitis. Little is known about acute renal failure as a consequence of Clostridium difficile-associated diarrhea.METHODS: In this case report, we describe the course of Clostridium difficile-associated diarrhea in an 82-yearold patient developing acute renal failure. Stopping the offending agent and symptomatic therapy brought a rapid improvement of diarrhea and acute renal failure, full recovery was gained 18 d after admission. In a systematic review we looked for links between the two conditions.RESULTS: The link between Clostridium difficilr-associated diarrhea and acute renal failure in our patient was most likely volume depletion. However, in experimental studies a direct influence of Clostridium difficile toxins on renal duct cells could be shown.CONCLUSION: Rapid diagnosis, nonspecific supportive treatment and specific antibiotic treatment, especially in the elderly, may lower excess mortality Clostridium difficile-associated diarrhea and renal failure being possible complications. | Jasmin Arrich Gottfried H.Sodeck Gürkan Seng(o|¨)lge Christoforos Konnaris Marcus Müllner Anton N.Laggner Hans Domanovits | 2005 | World Journal of Gastroenterology2005，11，8： | 15 |
| 2 | 睾丸主要血管或睾丸网旁取精点与取精成功率不具显著相关性:以220例非梗阻性无精子症患者行传统或显微睾丸取精术为例显示文摘采用传统与显微睾丸取精术相结合方式对220例梗阻性无精症患者行精子提取术,如果传统手术方式未见精子即为阴性取精位点,然后选取2—3个阴性取精位点行显微睾丸取精术。术中通过手术显微镜评价睾丸血管系统,同时记录阳性取精位点与睾丸血供的关系。总的精子获取率为58-2%,早期应用传统手术方式精子获取率为46.8%,而后行显微睾丸取精术则精子获取率增加11.7%。故显微睾丸取精术的应用可显著增加精子获取率(P=0.017),且在睾丸网或睾丸主要血管处并不能显著增加阳性取精位点。 | J Ullrich Schwarzer Heiko Steinfatt Heiko Steinfatt Manfred Schleyer Frank M Kōhn Klaus Fiedler2, Irene von Hertwig Gottfried Krüsmann Wolfgang Würfel | 2013 | Asian Journal of Andrology2013，15，6： | 5 |
| 3 | 电离层残差对掩星反演温度精度的影响显示文摘本文以MSIS90大气模式和3D NeUoG电离层模式为大气背景,用三维射线追踪法模拟研究了太阳活动强度、地方时、掩星平面方位角对弯曲角电离层残差和温度电离层残差的影响,以及电离层残差对全球日平均温度的影响.结果表明:电离层残差是平流层顶部(35-50 km)和中间层底部(50-70 km)掩星大气温度反演的主要误差.在太阳活动活跃期,电离层残差对单一掩星事件的平流层顶部平均温度的影响可达1.8 K,中间层底部平均温度的影响可达7 K;对全球日平均温度的影响在平流层顶可达-0.6 K,在70 km高度处可达1.2 K.发展新的电离层改正方法或电离层残差修正算法对提高掩星大气反演精度和全球气候监测意义重大. | 柳聪亮 Gottfried Kirchengast Kefei Zhang 谭志祥 Johannes Fritzer 孙越强 | 2014 | 地球物理学报2014，57，8： | 5 |
| 4 | 植物在修复、固定和重建水生、陆生生态系统中的应用显示文摘植物能够吸收或降解污染物来修复受污染的土壤和水体[1-2],还能固定土壤、泥沙防止侵蚀和污染物从固体介质中释放[3]。众多无机和有机污染物都能被对其有耐性且生物量大的植物有效降解。例如,凤眼莲能吸收和净化来自金矿采掘废水的氰化物,这类废水含各种氰化物以及重金属元素的浓度达到导致生物体产生毒性效应的水平。检测表明氰化物对凤眼莲的半数致死剂量(LC50)为13 mg/L,将经过高浓度氰化物废水驯化后的凤眼莲放在野外小型湿地进行试验,结果显示这类植物对氰化物的降解效率更高。放射性同位素试验发现氰化物分子中的C和N原子经过植物代谢合成天冬酰胺,从而将有毒性的氰化物转化为无毒的产物[4]。尾矿场也可以用植物来修复,一方面植物可以过滤污染物浓度很高的渗滤液,另一方面栽种植物可以固定边坡减少侵蚀。将高覆盖度植被的概念应用在一个尾矿场上,通过种植北美黄杉使其全年都维持较高的蒸腾效率来减少渗滤液。而边坡的固定首先需要在坡面安置固定、菱形的新鲜柳条编织成的笼状网格,其后覆上土壤并喷播能在生长期对固定土壤发挥作用的草本、灌木以及树木种子。这项技术同样适用于河岸侵蚀防护。 | Andreas SCHAEFFER 陈忠礼 Mathias EBEL Michael EVANGELOU Henner HOLLERT Martina RO-NICKOLL Burkhard SCHMIDT 袁野 Gottfried LENNARTZ | 2012 | 重庆师范大学学报(自然科学版)2012，29，3： | 4 |
| 5 | Inflammatory Bowel Disease Is a Risk Factor for Recurrent Venous Thromboembolism显示文摘 | Gottfried Novacek Ansgar Weltermann Anna Sobala Herbert Tilg Wolfgang Petritsch Walter Reinisch Andreas Mayer Thomas Haas Arthur Kaser Thomas Feichtenschlager Harry Fuchssteiner Peter Knoflach Harald Vogelsang Wolfgang Miehsler Reingard Platzer Wolfgang T | 2010 | Gastroenterology2010，，3： | 4 |
| 6 | Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management显示文摘 | Axel Dignass James O. Lindsay Andreas Sturm Alastair Windsor Jean-Frederic Colombel Mathieu Allez Gert D’Haens André D’Hoore Gerassimos Mantzaris Gottfried Novacek Tom ?resland Walter Reinisch Miquel Sans Eduard Stange Severine Vermeire Simon Travis Gert | 2012 | Journal of Crohn’s and Colitis2012，，10： | 4 |
| 7 | Metallic debris from metal-on-metal total hip arthroplasty regulates periprosthetic tissues显示文摘The era of metal-on-metal(MoM) total hip arthroplasty has left the orthopaedic community with valuable insights and lessons on periprosthetic tissue reactions to metallic debris. Various terms have been used to describe the tissue reactions. Sometimes the nomenclature can be confusing. We present a review of the concepts introduced by Willert and Semlitsch in 1977,along with further developments made in the understanding of periprosthetic tissue reactions to metallic debris. We propose that periprosthetic tissue reactions be thought of as(1) gross(metallosis, necrosis, cyst formation and pseudotumour);(2) histological(macrophage-dominated, lymphocyte-dominated or mixed);and(3) molecular(expression of inflammatory mediators and cytokines such as interleukin-6 and tumor necrosis factor-alpha). Taper corrosion and modularity are discussed, along with future research directions to elucidate the antigen-presenting pathways and materi-al-specific biomarkers which may allow early detection and intervention in a patient with adverse periprosthetic tissue reactions to metal wear debris. | Christoph H Lohmann Gurpal Singh Hans-Georg Willert Gottfried H Buchhorn | 2014 | World Journal of Orthopedics2014，5，5： | 3 |
| 8 | 圆锥角膜穿透性角膜移植术后缝线相关的角膜规则程度的动态变化显示文摘目的分析圆锥角膜(KC)手术前后角膜规则程度的变化,以及角膜缝线拆除对角膜规则程度的影响,对激光穿透性角膜移植手术(PK)在KC治疗中的作用进行评价。方法回顾分析了236例圆锥角膜使用激光环钻技术进行的穿透性角膜移植手术手术,使用角膜曲率计(Ophthalmometer,Type-H,190071Zeiss,Jena,Germany)对手术前后的角膜规则程度进行检测,并结合所测出的角膜曲率(K)值和角膜映光图像分成4组:(0)规则组,K〈50D;(1)轻度不规则组,K〈60;(2)中度不规则组,K≥60;(3)重度不规则组,K值不能读出,共4组。手术后第12、18个月依次拆除连续缝线,并同时随访记录各组别角膜规则程度,动态分析以上三个时间点角膜规则程度的变化特点。结果在三个时间点,规则组比例的递增趋势为4%-37%-61%轻度不规则组的变化趋势为12%-51%-33‰中度不规则组的递减趋势为38%-10%-4%;重度不规则组的变化趋势为46%-2%-2%。结论使用激光环钻和16针双线连续缝合的圆锥角膜手术病例中,穿透性角膜移植手术能有效改善病人的角膜表面规则程度,与缝线拆除相关的角膜规则程度呈动态变化,该变化主要发生在轻、中度组,缝线拆除本身并不会导致术后角膜规则程度下降。 | 刘毅 Berthold Seitz Achim Langenbucher Nhung X.Nguyen Gottfried O.H.Naumann | 2007 | 中国实用眼科杂志2007，25，4： | 3 |
| 9 | 状态监测——维修的最佳化显示文摘转向架状态监测为提高可靠性和安全性以及为实现低维修成本提供机会。在本文中,SKF公司的Fottfried Kure先生阐述如何使用状态监测工具和利用数据处理程序进行故障检测和避免机械故障的发生。 | Gottfried Kure 刘景宝 | 2010 | 国外内燃机车2010，，6： | 2 |
| 10 | Measurement of bound states in the continuum by a detector embedded in a photonic crystal显示文摘We directly measure optical bound states in the continuum(BICs)by embedding a photodetector into a photonic crystal slab.The BICs observed in our experiment are the result of accidental phase matching between incident,reflected and in-plane waves at seemingly random wave vectors in the photonic band structure.Our measurements were confirmed through a rigorously coupled-wave analysis simulation in conjunction with temporal coupled mode theory.Polarization mixing between photonic crystal slab modes was observed and described using a plane wave expansion simulation.The ability to probe the field intensity inside the photonic crystal and thereby to directly measure BICs represents a milestone in the development of integrated opto-electronic devices based on BICs. | Roman Gansch Stefan Kalchmair Patrice Genevet Tobias Zederbauer Hermann Detz Aaron M Andrews Werner Schrenk Federico Capasso Marko Lončar Gottfried Strasser | 2016 | Light(Science & Applications)2016，5，1： | 2 |
| 11 | Tissue factor exposing microparticles in inflammatory bowel disease显示文摘 | Julia Palkovits Gottfried Novacek Marietta Kollars Gregor Hron Wolf Osterode Peter Quehenberger Paul Alexander Kyrle Harald Vogelsang Walter Reinisch Pavol Papay Ansgar Weltermann | 2012 | Journal of Crohn’s and Colitis2012，，： | 2 |
| 12 | On the relationship between plant species diversity and genetic diversity of Plantago lanceolata(Plantaginaceae)within and between grassland communities显示文摘Aims and Methods The relationship between genetic diversity and species diversity and the underlying mechanisms are of both fundamental and applied interest.We used amplified fragment length polymorphism(AFLP)and vegetation records to investigate the association between genetic diversity of Plantago lanceolata and plant species diversity using 15 grassland communities in central Germany.We used correlation and partial correlation analyses to examine whether relationships between genetic and species diversity were direct or mediated by environmental differences between habitats.Important Findings Both within-and between-population genetic diversity of P.lanceolata were significantly positively correlated with plant species diversity within and between sites.Simple and partial correlations revealed that the positive correlations indirectly resulted from the effects of abiotic habitat characteristics on plant species diversity and,via abundance,on genetic diversity of P.lanceolata.Thus,they did not reflect a direct causal relationship between plant species diversity and genetic diversity of P.lanceolata,as would have been expected based on the hypothesis of a positive relationship between plant species diversity and niche diversity. | Nidal Odat Frank H.Hellwig Gottfried Jetschke Markus Fischer | 2010 | Journal of Plant Ecology2010，3，1： | 2 |
| 13 | Diffusion-and Peffusion-Weighted MRI Patterns in Borderzone Infarcts显示文摘 | Brian S Gottfried S | 2000 | Stioke2000，31，： | 1 |
| 14 | The ileal neobladder: complications and functional results in 363 patients after 11 years of follow-up 显示文摘 | Hautmann R E de Petriconi R Gottfried H W | 1999 | J Urol1999，161，2： | 1 |
| 15 | Ventilation muscle support in respiratory failure with nasal positive pressure ventilation显示文摘 | Carrey Z Gottfried SB Levy RD | 1990 | Chest1990，97，： | 1 |
| 16 | Pretreatment neutrophil-to-lymphocyte ratio in metastatic castration resist- ant prostate cancer patients treated with ketoconazole: associ- ation with outcome and predictive nomogram显示文摘 | Keizman D Gottfried M Ish-Shalom M | 2012 | Oncologist2012，17，12： | 1 |
| 17 | The ileal neo- bladder:complications and functional results in 363 patients af- ter 11 years of followup显示文摘 | Hautmann RE de Petriconi R Gottfried HW | 1999 | J Urol1999，161，2： | 1 |
| 18 | Alzheimer's disease and senile dementia: biochemical characteristics and aspects of treatment显示文摘 | Gottfries CG | 1985 | Psychopharmacology1985，86，3： | 1 |
| 19 | A miniaturized magnetic -field sensor system consisting of planar fluxgate sensor and a CMOS readout 显示文摘 | Gottfried- Gottfried R | 1996 | Sensors and Actuators A1996，66，： | 1 |
| 20 | Central neuro- cytoma:a review显示文摘 | Schemidt MH Gottfried ON von Koch CS | 2004 | J Neurooncol2004，66，： | 1 |
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