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| 1 | Newer perspectives of coronary artery disease in young显示文摘Coronary artery disease(CAD) occurring in less than 45 years of age is termed as young CAD.Recent studies show a prevalence of 1.2% of CAD cases in this age group.Ethnic wise south Asians especially Indians are more vulnerable to have CAD in young age group with a prevalence of 5% to 10%.Conventional risk factors such as smoking,diabetes,hypertension,obesity and family history seems to be as important as in older CAD subjects.But the prevalence of these risk factors seems to vary in younger subjects.By far the most commonly associated risk factor is smoking in young CAD.Several genes associated with lipoprotein metabolism are now found to be associated with young CAD like cholesterol ester transfer protein(CETP) gene,hepatic lipase gene,lipoprotein lipase gene,apo A1 gene,apo E gene and apo B.Biomarkers such as lipoprotein(a),fibrinogen,D-dimer,serum Wnt,gamma glutamyl transferase,vitamin D2 and osteocalcin are seems to be associated with premature CAD in some newer studies.In general CAD in young has better prognosis than older subjects.In terms of prognosis two risk factors obesity and current smoking are associated with poorer outcomes.Angiographic studies shows predominance of single vessel disease in young CAD patients.Like CAD in older person primary and secondary prevention plays an important role in prevention of new and further coronary events. | Amitesh Aggarwal Saurabh Srivastava M Velmurugan | 2016 | World Journal of Cardiology2016，8，12： | 13 |
| 2 | Isolation, identification, Pb(Ⅱ) biosorption isotherms and kinetics of a lead adsorbing Penicillium sp. MRF-1 from South Korean mine soil显示文摘A heavy metal contaminated soil sample collected from a mine in Chonnam Province of South Korea was found to be a source of heavy metal adsorbing biosorbents.Chemical analyses showed high contents of lead(Pb) at 357 mg/kg and cyanide(CN) at 14.6 mg/kg in the soil.The experimental results showed that Penicillium sp.MRF-1 was the best lead resistant fungus among the four individual metal tolerant fungal species isolated from the soil.Molecular characterization of Penicillium sp.MRF-1 was determined using ITS regions sequences.Effects of pH,temperature and contact time on adsorption of Pb(II) by Penicillium sp.MRF-1 were studied.Favorable conditions for maximum biosportion were found at pH 4 with 3 hr contact time.Biosorption of Pb(II) gradually increased with increasing temperature.Efficient performance of the biosorbent was described using Langmuir and Freundlich isotherms.Adsorption kinetics was studied using pseudo first-order and pseudo second-order models.Biosorbent Penicillium sp.MRF-1 showed the maximum desorption in alkali conditions.Consistent adsorption/desorption potential of the biosorbent in repetitive cycles validated the efficacy of it in large scale.SEM studies given notes on surface modification of fungal biomass under metal stress and FT-IR results showed the presence of amino groups in the surface structure of the biosorbent.In conclusion,the new biosorbent Penicillium sp.MRF-1 may potentially be used as an inexpensive,easily cultivatable material for the removal of lead from aqueous solution. | Natarajan Velmurugan Grim Hwang Muthuswamy Sathishkumar Tae Kie Choi Kui-Jae Lee Byung-Taek Oh Yang-Soo Lee | 2010 | Journal of Environmental Sciences2010，22，7： | 7 |
| 3 | Isolation and characterization of halophilic Bacillus sp.BS3 able to produce pharmacologically important biosurfactants显示文摘Objective:To characterize the pharmacological importance of biosurfactants isolated from halophilic Bacillus sp BS3.Methods:Halophilic Bacillus sp.BS3 was isolated from solar salt works,identified by 16S rRNA sequencing and was used for screening their biosurfactant production.Characters of the biosurfactant and their anticancer activity were analyzed and performed in mammary epithelial carcinoma cell at different concentrations.Results:The biosurfactant were characterized by TLC,FTIR and GC-MS analysis and identified as lipopeptide type.GC-MS analysis revealed that,the biosurfactant had various compounds including 13Docosenamide.(Z);Mannosamine,9- and N,N,N',N'-tetramethyl.Surprisingly the antiviral activity was found against shrimp white spot syndrome virus(WSSV) by suppressing the viral replication and significantly raised shrimp survival(P<0.01).Anticancer activity performed in the mammary epithelial carcinoma cell at different concentrations of biosurfactants,among the various concentrations of biosurfactants such as 0.000 25,0.002 5,0.025,0.25 and 2.5 μ g,the 0.25 μ g concentration suppressed the cells significantly(P<0.05) to 24.8%.Conclusions:Based on the findings,the present study concluded that,there is a possibility to develop eco-friendly antimicrobial and anticancer drugs from the extremophilic origin. | MBS Donio SFA Ronica V Thanga Viji S Velmurugan J Adlin Jenifer M Michaelbabu T Citarasu | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，11： | 5 |
| 4 | Supramolecular Nanohelix Fabricated by Pillararene-Based Host–Guest System for Chirality Amplification, Transfer, and Circularly Polarized Luminescence in Water显示文摘Amplified chirality and Förster resonance energy transfer(FRET)-assisted chirality transfer frommolecular to nanoscale level have been shown to play a vital role in co-assembled nanohelix for potential energy transfer in biological systems.Herein,we have constructed a chiral host–guest complex donor system for chiral amplification via induced chirality of pillar[5]arene host and loaded it with an achiral dye acceptor to demonstrate how chirality-assisted excitation energy transfer occurred in the supramolecular nanohelix system in an aqueous medium. | Krishnasamy Velmurugan Adil Murtaza Azhar Saeed Jianing Li Kaiya Wang Minzan Zuo Qian Liu Xiao-Yu Hu | 2022 | CCS Chemistry2022，4，10： | 3 |
| 5 | Chemical composition and antioxidant capacity of the aqueous extract of Phellodendron amurense显示文摘The aqueous extract of Phellodendron amurense Rupr.(Amur Cork Tree) provides a rich source of antioxidants and chemical compounds, and can be used for food and wood preservative materials.In this study, we characterized the chemical composition of this extract by GC and GC/MS.The antioxidant capacity was evaluated using a variety of antioxidant assays(superoxide radical,hydroxyl radical, nitric oxide radical, and DPPH radical scavenging activity).Additionally, total polyphenolic content was determined.Phenolic acids and acetone derivatives were major compounds of the extract capable of scavenging the DPPH free radical and reducing ferric ions.DPPH and ferric ion reduction results were strongly correlated with total phenolic content of the extract which also exhibited strong nitric oxide, hydroxyl radical scavenging and superoxide anion radical scavenging activities. | Natarajan Velmurugan Duraisamy Kalpana Jae Young Cho Yang Soo Lee | 2018 | Journal of Forestry Research2018，29，4： | 3 |
| 6 | A fractlonal-order delay differential model for Ebola infection and CD8+ T-cells response: Stability analysis and Hopf bifurcation显示文摘 | V. Preethi Latha R. Rakkiyappan G. Velmurugan | 2017 | International Journal of Biomathematics2017，10，8： | 3 |
| 7 | Combustion analysis of a hydrogen-diesel fuel operated DI diesel engine with exhaust gas recirculation显示文摘石块燃料和成长需求的快速的弄空要求研究人员发现干净、持续的其他的燃料。对发现可更新的需要,低费用和环境地友好的燃料资源永远不能被没有充分表达实情地陈述。产生的一个有效方法和氢的存储将使汽车的制造商能介绍氢造成的引擎在市场上。在这份报纸,一台常规 DI 柴油机引擎被修改作为煤气的引擎操作。引擎歧管的吸入与 recirculated 一起与氢被供应用尽气体和空气。氢的注射率与 2 酒吧的一个注射压力与 2 L/min 和 10 L/min 在三个层次被维持。许多象热一样的燃烧参数释放率(HRR ) ,点火延期,燃烧持续时间,压力上升(ROPR ) 的率,累积的热版本率(CHR ) ,和周期的压力变化被测量。HRR 山峰压力随 EGR 率的增加减少了,当燃烧持续时间与 EGR 率增加了时。周期的压力变化也随 EGR 率的增加增加了。 | M. LOGANATHAN A. VELMURUGAN TOM PAGE E. JAMES GUNASEKARAN P. TAMILARASAN | 2017 | Frontiers in Energy2017，11，4： | 2 |
| 8 | Influence of Geometric Design Variable and Bone Quality on Stress Distribution for Zirconia Dental Implants-A 3D Finite Element Analysis显示文摘This study aims to investigate the effects of variable thread pitch on stress distribution in bones of different bone qualities under two different loading conditions(Vertical,and Horizontal)for a Zirconia dental implant.For this purpose,a three dimensional finite element model of the mandibular premolar section and three single threaded implants of 0.8 mm,1.6 mm,2.4 mm pitch was designed.Finite element analysis software was used to develop the model and three different bone qualities(Type II,Type III,and Type IV)were prepared.A vertical load of 200 N,and a horizontal load of 100 N was applied at the abutment surface.The von-Mises stress criterion was used to analyze the results.The crestal bony-region of the mandibular section was subjected to maximum von-Mises stresses for all bone qualities.The outcome of this study indicates that,horizontal loading had more influence on stress distribution than vertical loading,regardless of the bone qualities and pitch values.Varying the dental implant pitch does not cause any decrease in stress distribution in bone,when the bone density decreased.The study concluded that implants with minimum pitch values induced lesser stress values at the implant-bone interface. | Duraisamy Velmurugan Masilamany Santha Alphin | 2018 | Computer Modeling in Engineering & Sciences2018，，11： | 2 |
| 9 | Relationship of tissue plasminogen activator plasminogen activator inhibitor 1 and fibrinogen with coronary artery disease in South Indian male subjects显示文摘 | Deepa R Velmurugan K Saravanan G | | 0，，： | 1 |
| 10 | Silibinin suppres- ses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of be- ta-catenin-dependent signaling 显示文摘 | Kaur M Velmurugan B Tyagi A | 2010 | Neoplasia2010，12，5： | 1 |
| 11 | Antimicrobial fabrication of cotton fabric and leather rising 显示文摘 | Velmurugan P Min Cho Sang - Myeong Lee | 2014 | Car- bohydrate Polymers2014，106，15： | 1 |
| 12 | An analysis of axial crushing of composite tubes显示文摘 | N K Gupta R Velmurugan S K Gupta | 1997 | Journal of Composite Material1997，31，13： | 1 |
| 13 | Integrate performance of stepped and single basin solar stills with mini solar pond显示文摘 | Velmurugan V Pandiarajan S Guruparan G | 2009 | Desalination2009，249，3： | 1 |
| 14 | Effect of light on growth,intracellular and extracellular pigment production by five pig-ment-producing filamentous fungi in synthetic medium显示文摘 | VELMURUGAN P LEE Y H VENIL C K | 2010 | Journal of Bioscience and Bioengineering2010，109，4： | 1 |
| 15 | Silibinin suppresses growth of human colorectal carcinoma SW480 cells in cuhure and xenograft through down-regulation of beta-catenin-depen- dent signaling显示文摘 | Kaur M Velmurugan B Tyagi A | 2010 | Neoplasia2010，12，5： | 1 |
| 16 | Productivity enhancement of stepped solar still performance analysis显示文摘 | Velmurugan V Senthil K S Niranjan P V | 2008 | Therm Sci2008，12，2： | 1 |
| 17 | Formation of zinc ferrite by solid-state reaction and its characterization by XRD and XPS显示文摘 | S. Bera A. A. M. Prince S. Velmurugan P. S. Raghavan R. Gopalan G. Panneerselvam S. V. Narasimhan | 2001 | Journal of Materials Science2001，，22： | 1 |
| 18 | Natural pigment extraction from five filamentous fungifor industrial applications and dyeing of leather显示文摘 | Velmurugan Kamala -Kannan Balachandar | 2010 | Carbohydrate Polymers2010，79，2： | 1 |
| 19 | Silibinin exerts sus- tained growth suppressive eftect against human colon careino- ma SW480 xenograft by targeting multiple signaling molecules 显示文摘 | Velmurugan B Gangar S C Kaur M | 2010 | Pharm Res2010，27，10： | 1 |
| 20 | Prevention of N - methyl N' - nitro - N - nitrosoguanidine and saturated sodium chloride - induced gastric carcinogenesis in Wistar rats by lycopene显示文摘 | Velmurugan B Bhuvaneswari V Burra UK | 2002 | Eur J Cancer Prey2002，11，1： | 1 |
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