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| 1 | Newer perspectives of coronary artery disease in young显示文摘Coronary artery disease(CAD) occurring in less than 45 years of age is termed as young CAD.Recent studies show a prevalence of 1.2% of CAD cases in this age group.Ethnic wise south Asians especially Indians are more vulnerable to have CAD in young age group with a prevalence of 5% to 10%.Conventional risk factors such as smoking,diabetes,hypertension,obesity and family history seems to be as important as in older CAD subjects.But the prevalence of these risk factors seems to vary in younger subjects.By far the most commonly associated risk factor is smoking in young CAD.Several genes associated with lipoprotein metabolism are now found to be associated with young CAD like cholesterol ester transfer protein(CETP) gene,hepatic lipase gene,lipoprotein lipase gene,apo A1 gene,apo E gene and apo B.Biomarkers such as lipoprotein(a),fibrinogen,D-dimer,serum Wnt,gamma glutamyl transferase,vitamin D2 and osteocalcin are seems to be associated with premature CAD in some newer studies.In general CAD in young has better prognosis than older subjects.In terms of prognosis two risk factors obesity and current smoking are associated with poorer outcomes.Angiographic studies shows predominance of single vessel disease in young CAD patients.Like CAD in older person primary and secondary prevention plays an important role in prevention of new and further coronary events. | Amitesh Aggarwal Saurabh Srivastava M Velmurugan | 2016 | World Journal of Cardiology2016，8，12： | 13 |
| 2 | Isolation and characterization of halophilic Bacillus sp.BS3 able to produce pharmacologically important biosurfactants显示文摘Objective:To characterize the pharmacological importance of biosurfactants isolated from halophilic Bacillus sp BS3.Methods:Halophilic Bacillus sp.BS3 was isolated from solar salt works,identified by 16S rRNA sequencing and was used for screening their biosurfactant production.Characters of the biosurfactant and their anticancer activity were analyzed and performed in mammary epithelial carcinoma cell at different concentrations.Results:The biosurfactant were characterized by TLC,FTIR and GC-MS analysis and identified as lipopeptide type.GC-MS analysis revealed that,the biosurfactant had various compounds including 13Docosenamide.(Z);Mannosamine,9- and N,N,N',N'-tetramethyl.Surprisingly the antiviral activity was found against shrimp white spot syndrome virus(WSSV) by suppressing the viral replication and significantly raised shrimp survival(P<0.01).Anticancer activity performed in the mammary epithelial carcinoma cell at different concentrations of biosurfactants,among the various concentrations of biosurfactants such as 0.000 25,0.002 5,0.025,0.25 and 2.5 μ g,the 0.25 μ g concentration suppressed the cells significantly(P<0.05) to 24.8%.Conclusions:Based on the findings,the present study concluded that,there is a possibility to develop eco-friendly antimicrobial and anticancer drugs from the extremophilic origin. | MBS Donio SFA Ronica V Thanga Viji S Velmurugan J Adlin Jenifer M Michaelbabu T Citarasu | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，11： | 5 |
| 3 | Silibinin suppres- ses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of be- ta-catenin-dependent signaling 显示文摘 | Kaur M Velmurugan B Tyagi A | 2010 | Neoplasia2010，12，5： | 1 |
| 4 | Silibinin suppresses growth of human colorectal carcinoma SW480 cells in cuhure and xenograft through down-regulation of beta-catenin-depen- dent signaling显示文摘 | Kaur M Velmurugan B Tyagi A | 2010 | Neoplasia2010，12，5： | 1 |
| 5 | Silibinin exerts sus- tained growth suppressive eftect against human colon careino- ma SW480 xenograft by targeting multiple signaling molecules 显示文摘 | Velmurugan B Gangar S C Kaur M | 2010 | Pharm Res2010，27，10： | 1 |
| 6 | Gallic acid, an active constituent of grape seed extract, exhibits anti-proliferative, proapoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth in nude mice 显示文摘 | Kaur M Velmurugan B Rajamanickam S | 2009 | Pharm Res2009，26，9： | 1 |
| 7 | Formation of zinc ferrite by solid-state reaction and itscharacterization by XRD and XPS显示文摘 | Bera S Prince A A M Velmurugan S | 2001 | J Mater Sci2001，36，22： | 1 |
| 8 | Optimal design of filament wound grid-stiffened composite cylindrical structures显示文摘 | Buragohain M Velmurugan R | 2011 | Defence Science Journal2011，61，1： | 1 |
| 9 | Study of filament wound grid-stiffened composite cylindrical structures显示文摘 | Buragohain M Velmurugan R | 2011 | Composite Structures2011，93，2： | 1 |
| 10 | Solid state synthesis of Mg-Ni ferrite and characterization by XRD and XPS 显示文摘 | MITTAL V K SANTANU BERA NITHYA R SRINIVASAN M P VELMURUGAN S NARASIMHAN S V | 2004 | Journal of Nuclear Materials2004，335，3： | 1 |
| 11 | Histo- pathology of lambda-cyhalothrin on tissues (gill, kidney, liver and intestine) of Cirrhinus mrigala 显示文摘 | Velmurugan B Selvanayagama M Cengiz E | 2007 | Environmen- tal Toxicology and Pharmacology2007，24，： | 1 |
| 12 | Thermal,mechanical and vibration characteristics of epoxy-clay nanocomposites显示文摘 | Mohan T P Ramesh K M Velmurugan R | 2006 | Journal of Material Science2006，41，18： | 1 |
| 13 | Dissolution behavior of magnetite film formed over carbon steel in dilute organic acid media显示文摘 | PRINCE A A M VELMURUGAN S NARASIMHANS V | | 0，，： | 1 |
| 14 | Antimicrobial fabrication of cotton fabrie and leather using green- synthesized nanosilver 显示文摘 | Velmurugan P Cho M Lee SM | 2014 | Carbohydrate Polymers2014，106，15： | 1 |
| 15 | Effect of reducing agent on graphene synthesis and its influence on charge storage towards supercapacitor applications显示文摘 | Ramachandran R Saranya M Velmurugan V | 2015 | Applied Energy2015，153，： | 1 |
| 16 | std1, a Gene involved in glucose transport in Schizosac charomyces pombe 显示文摘 | Shwetal V M Vandana BP Velmurugan S | 1998 | J Bacteriol1998，180，： | 1 |
| 17 | Single basin solar still with fin for enhancing productivity显示文摘 | VELMURUGAN V GOPALAKRISHNAN M RAGHU R | 2008 | Energy Conversion and Management2008，49，10： | 1 |
| 18 | Antibacterial activity of silver nanopartiele-coated fabrie and leather against odor and skin infection causing bacteria 显示文摘 | Velmurugan P Lee SM~ Cho M | 2014 | Applied Microbiology and Bioteehnology2014，98，19： | 1 |
| 19 | Histopathological changes in the gill and liver tissues of freshwater fish, Cirrhinus mrigalaexposed to dichlorvos显示文摘 | Velmurugan B Selvanayagam M Cengiz E I | 2009 | Brazilian Archives of Biology and Technology2009，52，5： | 1 |
| 20 | The effects of fenvalerate on different tissues of freshwater fish Cirrhinus mrigala 显示文摘 | Velmurugan B Selvanayagam M Cengiz El | 2007 | Journal of Environment Science and Health B2007，42，2： | 1 |
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