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| 1 | FibroSURE^(TM) and FibroScan~ in relation to treatment response in chronic hepatitis C virus显示文摘AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interferon-based therapy for 24(genotypes 2/3)or 48(genotype 1)wk.FibroSURE~TM(FS)was assessed at baseline and at week-12 post-treatment follow-up.Baseline biopsy for METAVIR was assessed by a single pathologist.FibroScan~ transient elastogra-phy(TE)was performed during treatment in a patient subset.RESULTS:Two thousand and sixty patients(n = 253 in Asia)were classif ied as METAVIR F0-1(n = 1682)or F2-4(n = 378).For F2-4,FS(n = 2055)had sensitiv-ity and specif icity of 0.87 and 0.61,respectively,with area under the receiver-operating curve of 0.82;corre-sponding values for TE(n = 214)and combined FS/TE(n = 209)were 0.77,0.88 and 0.88,and 0.93,0.68 and 0.88.Overall FS/TE agreement for F2-4 was 71%(κ = 0.41)and higher in Asians vs non-Asians(κ = 0.86 vs 0.35;P < 0.001).Combined FS/TE had 97% accuracy in Asians(n = 33).Baseline FS(0.38 vs 0.51,P < 0.001)and TE(8.0 kPa vs 11.9 kPa,P = 0.006)scores were lower in patients with sustained virological response than in nonresponders,and were maintained through follow-up.CONCLUSION:FS and TE may reliably differentiate mild from moderate-advanced disease,with a potential for high diagnostic accuracy in Asians with chronic HCV. | Keyur Patel Mireen Friedrich-Rust Yoav Lurie Mircea Grigorescu Carol Stanciu Chuan-Mo Lee Eugene R Schiff Dieter Hussinger Michael P Manns Guido Gerken Isabelle Colle Michael Torbenson Erik Pulkstenis G Mani Subramanian John G McHutchison Stefan Zeuzem | 2011 | World Journal of Gastroenterology2011，17，41： | 4 |
| 2 | Dietary Composition and Nonalcoholic Fatty Liver Disease显示文摘 | Steven Solga Amir R. Alkhuraishe Jeanne M. Clark Mike Torbenson Ashli Greenwald Anna Mae Diehl Thomas Magnuson | 2004 | Digestive Diseases and Sciences2004，，10： | 2 |
| 3 | Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model显示文摘 | Janaiah Kota Raghu R. Chivukula Kathryn A. O’Donnell Erik A. Wentzel Chrystal L. Montgomery Hun-Way Hwang Tsung-Cheng Chang Perumal Vivekanandan Michael Torbenson K. Reed Clark Jerry R. Mendell Joshua T. Mendell | 2009 | Cell2009，，6： | 2 |
| 4 | Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases显示文摘 | Georgios Karagkounis Michael S. Torbenson Hubert D. Daniel Nilofer S. Azad Luis A. Diaz Ross C. Donehower Kenzo Hirose Nita Ahuja Timothy M. Pawlik Michael A. Choti | 2013 | Cancer2013，，23： | 2 |
| 5 | Occult hepatitis B显示文摘 | Michael Torbenson David L Thomas | 2002 | The Lancet Infectious Diseases2002，，8： | 2 |
| 6 | Occult hepatitis B显示文摘 | Michael Torbenson David L Thomas | 2002 | Lancet Infect Dis2002，2，： | 1 |
| 7 | Diffusion- weighted magnetic resonance imaging for the staging of liver fi- brosis显示文摘 | Bonekamp S Torbenson M S Kamel I R et ai | 2011 | J ClinGastroenterol2011，45，10： | 1 |
| 8 | Haemophagocytic syndromes in sdults current concepts and challenges ahead显示文摘 | BRASTIANOS PK SWANSON JW TORBENSON M | 2005 | Swiss Med Wkly2005，135，2122： | 1 |
| 9 | Novel therapy for liver cancer: dirct intraarterial injection of potent inhibitor of ATP production显示文摘 | GESCHWIND JF KO YH TORBENSON MS | 2002 | Cancer Res2002，62，14： | 1 |
| 10 | Bile ducts and ductules are positive for CD56 (N-CAM) in most cases of extrahepatic biliary atresia显示文摘 | Torbenson M Wang J Abraham S | 2003 | Am J Surg Pathol2003，27，11： | 1 |
| 11 | Occult hepatitis B显示文摘 | Torbenson M Thomas DL | 2002 | Lancet Infect Dis2002，2，8： | 1 |
| 12 | Glycogenic hepatopathy : an underrecognized hepatic complication of diabetes mellitus 显示文摘 | Torbenson M Chen YY Brunt E | 2006 | Am J Surg Pathol2006，30，4： | 1 |
| 13 | Tuberculosis associated haemophagocytic syndrome显示文摘 | Brastianos PK Swanson JW Torbenson M | 2006 | Lancet Infect Dis2006，6，7： | 1 |
| 14 | Rapid fibroSiS progreSSion amongHIV/hepatitiS C viruS-co-infected adultS 显示文摘 | SulkowSki MS Mehta S H TorbenSon MS | | AIDS0，21，16： | 1 |
| 15 | Limited effectiveness of antiviral treatment for hepatitis C in an urban HIV clinic显示文摘 | Shruti H Mehta Gregory M Lucas Lisa B Mirel Michael Torbenson Yvonne Higgins Richard D Moore David L Thomas Mark S Sulkowski | 2006 | AIDS2006，，18： | 1 |
| 16 | Inflammatory pseudotumor of the liver显示文摘 | Locke JE Choti MA Torbenson MS | 2005 | J Hepatobiliary Pancreat Surg2005，12，： | 1 |
| 17 | Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases显示文摘 | Georgios Karagkounis Michael S. Torbenson Hubert D. Daniel Nilofer S. Azad Luis A. Diaz Ross C. Donehower Kenzo Hirose Nita Ahuja Timothy M. Pawlik Michael A. Choti | 2013 | Cancer2013，，23： | 1 |
| 18 | Review of the clinicopathologic features of fibrolamellar carcinoma显示文摘 | Torbenson M | | 0，，03： | 1 |
| 19 | Rapid fibrosis progression among HIV/hepatitis C virus-co-infected adults显示文摘 | Sulkowski MS Mehta SH Torbenson MS | 2007 | AIDS2007，21，16： | 1 |
| 20 | Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production显示文摘 | Geschwind JF Ko YH Torbenson MS | 2002 | Cancer Res2002，62，14： | 1 |
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