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| 1 | A gist of gastrointestinal stromal tumors: A review显示文摘Gastrointestinal stromal tumors (GISTs) have been recognized as a biologically distinctive tumor type, different from smooth muscle and neural tumors of the gastrointestinal tract (GIT). They constitute the majority of gastrointestinal mesenchymal tumors of the GIT and are known to be refractory to conventional chemotherapy or radiation. They are defined and diagnosed by the expression of a proto-oncogene protein detected by immunohistochemistry which serves as a crucial diagnostic and therapeutic target. The identification of these mutations has resulted in a better understanding of their oncogenic mechanisms. The remarkable antitumor effects of the molecular inhibitor imatinib have necessitated accurate diagnosis of GIST and their distinction from other gastrointestinal mes-enchymal tumors. Both traditional and minimally invasive surgery are used to remove these tumors with minimal morbidity and excellent perioperative outcomes. The revolutionary use of specific, molecularlytargeted therapies, such as imatinib mesylate, reduces the frequency of disease recurrence when used as an adjuvant following complete resection. Neoadjuvant treatment with these agents appears to stabilize disease in the majority of patients and may reduce the extent of surgical resection required for subsequent complete tumor removal. The important interplay between the molecular genetics of GIST and responses to targeted therapeutics serves as a model for the study of targeted therapies in other solid tumors. This review summarizes our current knowledge and recent advances regarding the histogenesis, pathology, molecular biology, the basis for the novel targeted cancer therapy and current evidence based management of these unique tumors. | Ashwin Rammohan Jeswanth Sathyanesan Kamalakannan Rajendran Anbalagan Pitchaimuthu Senthil-Kumar Perumal UP Srinivasan Ravi Ramasamy Ravichandran Palaniappan Manoharan Govindan | 2013 | World Journal of Gastrointestinal Oncology2013，5，6： | 27 |
| 2 | In vitro antioxidant activities of ethanol extract from Enhalus acoroides (L.F.) Royle显示文摘Objective:To search for new sources of safe and inexpensive antioxidants,the leaf,root and rhizome of Enhalus acoroides(E.acoroides) were screened for the first time for their antioxidant activities.Methods:Samples of leaf,root and rhizome from E.acoroides were tested for total phenolic content,proanthocyanidins and in vitro antioxidant activity in terms of total antioxidant assay,DPPH assay and FRAP assay.Results:The leaf sample was found to have high levels of phenolic(0.323±0.028 mg TAE/g) and proanthocyanidins(0.570 0±0.000 3 mg TAE/g) when compared to root and rhizome.The leaf samples exhibited higher total antioxidant activity (11.770±0.026 mg Ascorbic acid equivalent/g),higher percentage of DPPH radical scavenging activity(25.76±0.04) and higher reducing power(18.060±0.073) in terms of mg GAE/g.In addition, there was a significant correlation between total phenolic content and total antioxidant activity (R^2=0.923),DPPH assay(R^2=0.509).FRAP assay(R^2=0.994).Similarly,significant correlation was found between the proanthocyanidin and total antioxidant activity(R^2=0.977),DPPH assay (R^2=0.464) and the FRAP assay(R^2=0.998).Conclusions:These results suggested that E.acoroides have strong antioxidant potential.Further study is necessary for isolation and characterization of the active antioxidant agents,which can be used to treat various oxidative stress-related diseases. | Rengasamy Ragupathi Raja Kannan Rajasekaran Arumugam Perumal Anantharaman | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 15 |
| 3 | Antioxidant activities of Indigofera cassioides Rottl.Ex.DC.using various in vitro assay models显示文摘Objective:To evaluate the antioxidant potential of methanolic leaf extract of Indigofera cassioides(MEIC) using various in vilro antioxidant assay systems.Methods:Antioxidant and free radical scavenging activity of MEIC was assayed by using different in vitro models like ABTS, DPPH,nitric oxide,superoxide,hydrogen peroxide and hydroxyl radical.Reductive ability of the extract was tested by the complex formation with potassium ferricyanide.Further total phenol and flavonoid contents of the crude extract were also determined.Rutin and ascorbic acid were used as standards.Results:MEIC exhibited potent and concentration dependent free radical scavenging activity in all the tested models.Reductive ability was also found to increase with increase in MEIC concentration.Total phenol and flavonoid content determination showed that the extract is rich in phenols and flavonoids.Conclusions:All the results of the in vitro antioxidant assays reveal potent antioxidant and free radical scavenging activity of the leaves of Indigofera cassioides,equivalent to that of standard ascorbic acid and rutin.This potent antioxidant activity may be attributed to its high phenolic and flavonoid contents. | R Senthil Kumar B Rajkapoor P Perumal | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 15 |
| 4 | Evaluation of pedestrian mid-block road crossing behaviour using artificial neural network显示文摘Pedestrians usually cross the road at mid-block locations in India because of the ease and convenience to reach their destination as compared to intersection locations.It is important to evaluate the pedestrian gap acceptance behavior at mid-block locations because of inadequate vehicular gaps under mixed traffic condition,which translates into the pedestrian road crossing behavior.The present study examines the pedestrian gap acceptance behaviour by employing an artificial neural network(ANN) model for understanding the decision making process of pedestrians,i.e.,acceptance or rejection of vehicular gaps at a mid-block location.From the results it has been found that the pedestrian rolling gap,frequency of attempt,vehicular gap size,pedestrian speed change condition and vehicle speed have major role in pedestrian gap acceptance.These results can lead to a better design of pedestrian crossing facilities where adequate gaps are not available in vehicular flow at mid-block crosswalk locations. | B Raghuram Kadali Nivedan Rathi Vedagiri Perumal | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014，1，2： | 13 |
| 5 | Embolization of liver tumors:Past,present and future显示文摘Curative therapies for hepatocellular carcinoma(HCC),such as resection and liver transplantation,can only be applied in selected patients with early tumors.More advanced stages require local or systemic therapies.Resection of HCC offers the only hope for cure.Even in patients undergoing resection,recurrences are common.Chemoembolization,a technique combining intraarterial chemotherapy with selective tumor ischemia,has been shown by randomized controlled trials to be efficacious in the palliative setting.There is now renewed interest in transarterial embolization/transarterial chemoembolization(TACE) with regards to its use as a palliative tool in a combined modality approach,as a neoadjuvant therapy,in bridging therapy before transplantation,for symptomatic indications,and even as an alternative to resection.There have also been rapid advances in the agents being embolized trans-arterially(genes,biological response modifiers,etc.).The current review provides an evidence-based overview of the past,present and future trends of TACE in patients with HCC. | Ashwin Rammohan Jeswanth Sathyanesan Sukumar Ramaswami Anand Lakshmanan Perumal Senthil-Kumar Ulagendra Perumal Srinivasan Ravi Ramasamy Palaniappan Ravichandran | 2012 | World Journal of Radiology2012，4，9： | 11 |
| 6 | In vitro antioxidant,anti-diabetic,cholinesterase and tyrosinase inhibitory potential of fresh juice from Citrus hystrix and C.maxima fruits显示文摘In the present study,antioxidant potential,α-amylase,α-glucosidase,cholinesterase and tyrosinase inhibitory activity of fresh juice from indigenous fruits of Citrus hystrix and C.maxima(Red&White var.)were investigated using an in vitro model.The contents of total phenolics,tannins,and total flavonoids ranged between 836.90 and 909.52 mg gallic acid equivalent(GAE)/L,333.33 and 523.21 mg gallic acid equivalent(GAE)/L and 224.88 and 262.22 mg rutin equivalent/L,respectively.The antioxidant activity of fresh juice was evaluated by employing different in vitro assays such as reducing power assay,DPPH•,ABTS•+and•OH radical scavenging capacities,peroxidation inhibition activity,antihemolytic assay.In addition,75.55%–79.75%ofα-amylase and 70.68%–72.83%ofα-glucosidase enzyme inhibition characteristics were found under in vitro starch digestion bioassay.Also,all the juice samples exhibited excellent tyrosinase(76.95%–80.79%),acetylcholinesterase(75.71%–79.74%)andβ-glucuronidase inhibitory activity(68.13%–69.38%).These results indicated that fresh juice of C.hystrix and C.maxima(Red&White var.)could be used as a source of antioxidant agents,functional food and nutraceuticals.©2014 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Arumugam Abirami Gunasekaran Nagarani Perumal Siddhuraju | 2014 | Food Science and Human Wellness2014，3，1： | 8 |
| 7 | Antibacterial potential of three seagrasses against human pathogens显示文摘Objective:To evaluate the antibacterial activity of Halophila stipulacea(H.stipulacea), Cymodocea serrulata(C.serrulata) and Halodule pinifolia(H.pinifolia) against seven human bacterial pathogens.Methods:The antibacterial activities of the extracts on the various test organisms using disc diffusion method and Minimum Inhibitory Concentraction(MIC).Results: Methanol and chloroform extracts of all the three seagrasses were active against all the tested pathogens,whereas the hexane extract of seagrasses was not active against Staphylococcus aureus (S.aureus).Antibacterial activity of three seagrass screened,was in the order of H.pinifolia > H.stipulacea.> C.serrulata.Conclusions:This antibacterial studies can further investigated on seagrasses for purification of bioactive substance and its possible utility in disease control. | Rengasamy Ragupathi Raja Kannan Rajasekaran Arumugam Perumal Anantharaman | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 7 |
| 8 | Genetically modified mouse models for the study of nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) is associated with obesity,insulin resistance,and type 2 diabetes.NAFLD represents a large spectrum of diseases ranging from(1) fatty liver(hepatic steatosis);(2) steatosis with inflammation and necrosis;to(3) cirrhosis.The animal models to study NAFLD/nonalcoholic steatohepatitis(NASH) are extremely useful,as there are still many events to be elucidated in the pathology of NASH.The study of the established animal models has provided many clues in the pathogenesis of steatosis and steatohepatitis,but these remain incompletely understood.The different mouse models can be classified in two large groups.The first one includes genetically modified(transgenic or knockout) mice that spontaneously develop liver disease,and the second one includes mice that acquire the disease after dietary or pharmacological manipulation.Although the molecular mechanism leading to the development of hepatic steatosis in the pathogenesis of NAFLD is complex,genetically modified animal models may be a key for the treatment of NAFLD.Ideal animal models for NASH should closely resemble the pathological characteristics observed in humans.To date,no single animal model has encompassed the full spectrum of human disease progression,but they can imitate particular characteristics of human disease.Therefore,it is important that the researchers choose the appropriate animal model.This review discusses various genetically modified animal models developed and used in research on NAFLD. | Perumal Nagarajan M Jerald Mahesh Kuma Ramasamy Venkatesan Subeer S Majundar Ramesh C Juyal M Jerald Mahesh Kuma | 2012 | World Journal of Gastroenterology2012，18，11： | 7 |
| 9 | In vitro antioxidant activities of selected seaweeds from Southeast coast of India显示文摘Objective:In vitro antioxidant activities of three selected Indian seaweeds viz.,Halimeda tuna(H.tuna),Turbinaria conoides(T.conoides) and Gracilaria foliifera(G.foliifera) were evaluated.Methods:Total antioxidant activity,total phenolic content,and reducing power of crude methanol and diethyl ether extracts were determined.Results:Total phenolic content and total antioxidant activity were higher(1.231±0.173 mg GAE/g,1.675±0.361 mg GAE/g) in T.conoides respectively.Reducing power of crude methanol extract increased with concentrations of the extract.The Fourier transform-infra red spectrum analysis revealed the presence of polyphenolic signals.The seaweed extracts displayed moderate antioxidant activity compared to gallic acid standard.Conclusions:The seaweeds could be considered for curing diseases from oxidative deteriorations. | Gopalraj Karthikai Devi Karunamoorthy Manivannan Ganapathy Thirumaran Fatimson Arockiya Aarthi Rajathi Perumal Anantharaman | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，3： | 6 |
| 10 | In vitro and in vivo anticancer activity of Indigofera cassioides Rottl.Ex. DC.显示文摘Objective:To evaluate the antitumor,cytotoxic and antioxidant activities of methanolic leaf extract of Indigofera cassioides(MEIC) against transplantable tumors and human cancer cell lines.Methods:MEIC was investigated for its short term cytotoxicity on EAC and DLA cells by trypan blue dye exclusion method and in vitro cytotoxicity on HeLa,HEp-2,HEpG-2,MCF-7, HT-29,Vero and NIH 3T3 cells by MTT assay.In vivo antitumor activity was studied on EAC and DLA tumor bearing mice.Activity was assessed by monitoring the mean survival time,effect on hematological parameters,antioxidant enzyme levels and solid tumor volume.Results:MEIC exhibit potent in vitro cytotoxicity against all the tested cancer cell lines,but it was found to be safe on normal cells.The extract significantly(P<0.001) increase the mean survival time and also have a protective effect on the hemopoietic system at the tested dose levels(200 and 400 mg/kg). The extract prevented lipid peroxidation and restored the antioxidant enzymes catalase, superoxide dismutase,glutathione peroxidase and glutathione-s-transferase in the liver of tumor control animals.It also significandy(P<0.01) reduce the solid tumor volume.Conclusions:The results strongly support that MEIC shows potent antitumor and cytotoxic effects against EAC,DLA and human cancer cell lines.The extract prevents lipid peroxidation and promotes the enzymatic antioxidant defense system in tumor bearing animals which might be due to activities like scavenging of free radicals by the phytochemicals in MEIC. | Raju Senthil Kumar Balasubramanian Rajkapoor Perumal Perumal | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，5： | 6 |
| 11 | Study on pedestrian crossing behavior at signalized intersections显示文摘A clear understanding of pedestrian crossing behavior under mixed traffic conditions is needed for providing necessary infrastructure and also for enhancing pedestrian safety at signalized intersections.This paper attempts to analyze the crossing behavior of pedestrians like crossing speed,compliance with signal,and pedestrian-vehicular interaction under mixed traffic conditions and to identify the influencing factors based on statistical tests.775 pedestrian samples were observed from three signalized intersections in Mumbai,India for analyzing crossing behaviors and the significant factors affecting traffic signal compliance by pedestrians were identified by conducting Pearson's correlation coefficient test,ANOVA test,and Student t test.Factors influencing pedestrian crossing speed had been studied and a design crossing speed had been determined for old and adult pedestrians at 0.95 m/s and1.12 m/s respectively.Logistic regression models had been developed in which the odds of pedestrian violation and interactions were modeled and verified.This study can help researchers and practitioners to understand pedestrian crossing behavior at signalized intersections and develop pedestrian delay models under mixed traffic conditions. | Marisamynathan Vedagiri Perumal | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014，1，2： | 6 |
| 12 | 宏基因组学分析揭示深古菌Bathyarchaeota B242的代谢特征显示文摘【背景】海洋沉积物中蕴含着丰富的微生物资源,估算约2.9×1029个细胞,与海水中的微生物总量相当。但是由于缺少可培养物,大部分的微生物缺乏生理特征、代谢方式以及生态功能的相关研究。深古菌(Bathyarchaeota)是一类典型的未培养微生物,在全球海洋沉积物中普遍存在,并且具有很高的丰度。【目的】对深古菌代谢潜能及其在海洋沉积物中发挥的生态功能进行更加深入的研究。【方法】应用宏基因组学的技术手段,对采集自瓜伊马斯盆地的深海热液沉积物样本进行了分析,获得了一个接近完整的深古菌基因组Bathyarchaeota B242。【结果】对Bathyarchaeota B242基因组的分析发现,其具有以降解蛋白质和多种碳水化合物为主的异养代谢途径,同时还具有通过还原型乙酰辅酶A途径实现的自养途径。【结论】同时具有自养和异养代谢途径对Bathyarchaeota B242适应低物质能量供给环境下的生存起到重要作用。 | 冯晓远 Venki Perumal 王风平 | 2018 | 微生物学通报2018，45，1： | 5 |
| 13 | A comparative study on antioxidant potentials,inhibitory activities against key enzymes related to metabolic syndrome,and anti-inflammatory activity of leaf extract from different Momordica species显示文摘Momordica species are vegetable crops widely distributed in warmer regions of the world.In this work,we describe the antioxidant,enzyme inhibitory and anti-inflammatory effects of the leaves from three different species of Momordica.The present investigation was initially carried out to explore the possible link between antioxidant,enzyme inhibitory property of Momordica leaf extract and their total phenolic and flavonoid contents.The anti-inflammatory activity was tested by using carrageenan-induced paw edema.Our results illustrated an enhanced antioxidant power of wild species comparable with a commercial variety.In addition,the leaf extract of M.dioica(200 mg/kg)presented a significant anti-inflammatory activity toward carrageenan-induced paw edema in Wistar rats in comparison to indomethacin(10 mg/kg).The contents of flavonoids and total phenolic compounds could be correlated with the antioxidant and enzymes inhibition activities.The major bioactive compounds of phenolic acids and flavonoids such as gallic acid,chlorogenic acid,caffeic acid,ferulic acid,ellagic acid,catechin,rutin,and quercetin were identified.Our findings suggest that wild Momordica species contains higher potential antioxidant and anti-inflammatory activities than a commercial variety does,which could be tested as drug candidates against oxidative and inflammation-related pathological processes.©2014 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Gunasekaran Nagarani Arumugam Abirami Perumal Siddhuraju | 2014 | Food Science and Human Wellness2014，3，1： | 4 |
| 14 | Predictors of malignancy in chronic calcific pancreatitis with head mass显示文摘AIM: To prospectively analyse the clinical, biochemical and radiological characteristics of the mass lesions arising in a background of chronic calcific pancreatitis (CCP). METHODS: Eighty three patients, who presented with chronic pancreatitis (CP) and a mass lesion in the head of pancreas between February 2005 and December 2011, were included in the study. Patients who were identified to have malignancy underwent Whipple' s procedure and patients whose investigations were suggestive of a benign lesion underwent Frey's procedure. Student t-test was used to compare the mean values of imaging findings [common bile duct (CBD), main pancreatic duct (MPD) size] and laboratory data [Serum bilirubin, carbohydrate antigen 19-9 (CA 19-9)] between the groups. Receiver operating characteristic curve (ROC curve) analysis was done to calculate the cutoff valves of serum bilirubin, CA 19-9, MPD and CBD size. The sensitivity, specificity, positive predictive valve (PPV) and negative predictive value (NPV) were calculated using these cut off points. Multivariate analysis was performed using logistic regression model. RESULTS: The study included 56 men (67.5%) and 27 women (32.5%). Sixty (72.3%) patients had tropical calcific pancreatitis and 23 (27.7%) had alcohol related CCP. Histologically, it was confirmed that 55 (66.3%) of the 83 patients had an inflammatory head mass and 28 (33.7%) had a malignant head mass. The mean age of individuals with benign inflammatory mass and those with malignant mass was 38.4 years and 45 years respectively. Significant clinical features that predicted a malignant head mass in CP were presence of a head mass in CCP of tropics, old age, jaundice, sudden worsening abdominal pain, gastric outlet obstruction and significant weight loss (P ≤ 0.05). The ROC curve analysis showed a cut off value of 5.8 mg/dL for serum bilirubin, 127 U/mL for CA 19-9, 11.5 mm for MPD size and 14.5 mm for CBD size. CONCLUSION: Elevated Serum bilirubin and CA 19-9, and dilated MPD and CBD were useful in predicting malignancy in patients with CCP and head mass. | Senthilkumar Perumal Ravichandran Palaniappan Sastha Ahanatha Pillai Vimalraj Velayutham Jeswanth Sathyanesan | 2013 | World Journal of Gastrointestinal Surgery2013，5，4： | 4 |
| 15 | 结核病的性别差异:南印度某农村地区DOTS项目报告显示文摘背景:南印度 Tiruvallur 地区。目的:了解 14 岁以上成年人在结核感染和患病、就医途径、就医行为、诊断延误、接受 DOT的方便程度、疾病歧视以及治疗依从性等方面的性别差异。方法:相关数据主要来自:1)社区调查,2)在公立初级保健卫生机构(PHIS)主动就医的病人,3)转诊到 PHIS 进行痰涂片检查的可疑结核病人;4)DOTS 策略下的登记报告结核病人。并将社区调查结果与 PHIS 登记病人进行比较。结果:社区人群中 66%的男性和 57%的女性感染了结核菌;男性和女性的涂阳肺结核患病率分别为568/10 万和87/10 万。在 PHIS 就医的男性少于女性,男女之比为 68:100。女性占社区调查发现涂阳病人的 13%;占 PHIS 发现病人的 20%(P<0.05)。随着年龄的增长,男性和女性的登记率显著降低。女性感觉难于与家人讨论自己病情的比例要高于男性(21%∶14%),也更需要有人陪伴去接受 DOT(11%∶6%)。男性的治疗中断率比女性高 1 倍(19%∶8%;P<0.01)。结论:尽管女性发病后更容易遭受歧视和不便,但女性更易于利用医疗服务、接受 DOTS 策略登记以及依从治疗。而男性以及高龄病人在诊断和 DOT服务方面更需要帮助。 | R. Balasubramanian R. Garg T. Santha P. G. Gopi R. Subramani V. Chandrasekaran A. Thomas R. Rajeswari S. Anandakrishnan M. Perumal C. Niruparani G. Sudha K. Jaggarajamma T. R. Frieden P. R. Narayanan 刘小秋 | 2004 | 结核与肺部疾病杂志2004，7，4： | 4 |
| 16 | Synthesis,characterization and sintering behavior influencing mechanical,thermal and physical properties of pure cordierite and cordierite-ceria显示文摘The study of cordierite ceramic is the need of the hour in present technological world for various advanced engineering applications.Cordierite,which has relatively poor mechanical properties,has induced the use of various dopants to study the improvement in mechanical properties.Thirst of seeking new materials with good mechanical properties has revived the research on ceria doped cordierite.Present research conducted on pure cordierite and ceria doped cordierite ceramics has investigated the results of characterization and studied their suitability.Pure cordierite and cordierite-ceria(CeO_(2))composite ceramics synthesized for various stoichiometric composition(5-20 wt%)were compacted at 240 MPa and sintered between 600℃and 1350℃for 3 h.The characterization techniques used in this study were X-ray diffraction(XRD),thermogravimetric(TG)analysis and Fourier transform infrared(FTIR).The density was calculated using the Archimedes principle.Influence of the ceria addition on cordierite’s mechanical properties such as hardness,flexural strength and fracture toughness and on thermal properties as thermal expansion was studied.XRD results confirmed the presence of cordierite and ceria in the samples heat treated at 1350℃.Results of FTIR and TG analyses revealed the formation of cordierite and the effect of ceria addition.The mechanical properties studied were found to be encouraging and confirmed the suitability of cordierite-ceria as an alternate material for cordierite. | Marikkannan SENTHIL KUMAR Ayyasamy ELAYA PERUMAL T.R.VIJAYARAM | 2015 | Journal of Advanced Ceramics2015，4，1： | 3 |
| 17 | Hepatoprotective effect of leaf extracts from Citrus hystrix and C.maxima against paracetamol induced liver injury in rats显示文摘The present investigation is aimed to evaluate the hepatoprotective effects of Citrus hystrix and Citrus maxima(Red and White variety)methanolic leaf extracts on paracetamol induced toxicity.Leaf extracts were given in the dose of 200 mg/kg body weight for 7 days and toxicity was induced by paracetamol(2 g/kg)on day 5.Silymarin(100 mg/kg body weight)was used as reference standard.On the 7th day animals were sacrificed and liver function markers(ALT,AST,ALP),total bilirubin and total protein in blood serums and hepatic antioxidants(SOD,CAT,GSH and GPx)in liver homogenate were estimated.The leaf extracts restored the liver function markers and hepatic antioxidants to the normal level than elevated levels noticed on paracetamol control at P<0.001.Reversal of hepatoarchitecture has also been registered.The present study shows that C.hystrix and C.maxima leaf extracts possess hepatoprotective action against paracetamol induced hepatotoxicity.©2015 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Arumugam Abirami Gunasekaran Nagarani Perumal Siddhuraju | 2015 | Food Science and Human Wellness2015，4，1： | 3 |
| 18 | Seasonal variations of phytoplankton diversity in the Coleroon coastal waters,southeast coast of India显示文摘The results of an investigation carried out during June 2005 to May 2007 on physico-chemical parameters,species composition and community structure of phytoplankton including Chlorophyll a(Chl-a) at the Coleroon coastal waters(Southeast coast of India) are reported.Air and surface water temperatures(°C) varied from 25.1 to 30.1 and from 24.5 to 28.5 respectively.Salinity values varied from 6 to 28.5 and the pH ranged between 7.0 and 8.3.Variation in dissolved oxygen content was from 3.1 to 7.5 mg/dm-3 while the light extinction coefficient values(LEC) ranged between 3.1 and 10.1 cm.The ranges of inorganic nutrients(μmol/dm-3) viz.,nitrate,nitrite,phosphate and silicate were 10.1-23.4,1.2-8.9,0.2-3.1 and 55-125,respectively.The ranges of Chlorophyll a(μg/dm-3) values was 2.0-7.5.Presently,124 phytoplankton species representing different classes viz:Bacillariophyceae(77),Dinophyceae(19),Cyanophyceae(15),Chlorophyceae(10) and Chrysophyceae(3) were recorded.The phytoplankton cell abundance varied from 0.290 to 111.662 cells/cm-3,with peak diversity(3.38 bits/ind.) during summer season.The maximum abundance was found during summer season coinciding with the stable hydrographical conditions.The seasonal distribution and abundance of phytoplankton are discussed in relation to hydrographical parameters.Canonical Correspondence Analysis(CCA) was applied in this paper for discriminating environmental factors having effect on phytoplankton community at species level.Coleroon coastal water is subjected to long term fluctuations in physico-chemical parameters depending upon the seasonal tidal amplitude and freshwater influx resulting in a continuous exchange of organic,inorganic,plant and animal matters. | Thillai Rajasekar K Rajkumar M SUN Jun Ashok Prabu V Perumal P | 2010 | Acta Oceanologica Sinica2010，29，5： | 3 |
| 19 | Implications of the presence of an aberrant right hepatic artery in patients undergoing pancreaticoduodenectomy显示文摘AIM:To analyze the differences in outcomes and the clinical impact following pancreatoduodenectomy(PD)in patients with and without aberrant right hepatic artery(aRHA).METHODS:All patients undergoing PD between January 2008 and December 2012 were divided into two groups,one with aRHA and the other without.These groups were compared to identify differences in the intraoperative variables,the oncological clearance and the postoperative morbidity,mortality and hospital stay.RESULTS:A total of 225 patients underwent PD,of which 43(19.1%)patients were found to have eitheraccessory or replaced right hepatic arteries(aRHA group).The aRHA was preserved in 79%of the patients.There was no significant difference in the intraoperative blood loss but operative time was prolonged,reflecting the complexity of the procedure[420±44(240-540)min vs 480±45(300-600)min,P<0.05)].There were no differences in the incidence of postoperative complications(pancreatic leak,pancreatic fistula,delayed gastric emptying and mortality)and hospital stay.Oncological clearance in the form of positive resection margins[13(7.1%)vs 3(6.9%)]and lymph node yield were also similar in the two groups.CONCLUSION:An aRHA is found in approximately one fifth of patients undergoing PD.Preservation is technically possible in most patients and can increase the operative complexity but does not negatively affect the safety or oncological outcomes of the procedure. | Ashwin Rammohan Ravichandran Palaniappan Anbalagan Pitchaimuthu Kamalakannan Rajendran Senthil Kumar Perumal Kesavan Balaraman Ravi Ramasamy Jeswanth Sathyanesan Manoharan Govindan | 2014 | World Journal of Gastrointestinal Surgery2014，6，1： | 3 |
| 20 | Mine tailings as a raw material in alkali activation: A review显示文摘The mining industry produces billions of tons of mine tailings annually.However,because of their lack of economic value,most of the tailings are discarded near the mining sites,typically under water.The primary environmental concerns of mine tailings are related to their heavy metal and sulfidic mineral content.Oxidation of sulfidic minerals can produce acid mine drainage that leaches heavy metals into the surrounding water.The management of tailing dams requires expensive construction and careful control,and there is the need for stable,sustainable,and economically viable management technologies.Alkali activation as a solidification/stabilization technology offers an attractive way to deal with mine tailings.Alkali activated materials are hardened,concrete-like structures that can be formed from raw materials that are rich in aluminum and silicon,which fortunately,are the main elements in mining residues.Furthermore,alkali activation can immobilize harmful heavy metals within the structure.This review describes the research on alkali activated mine tailings.The reactivity and chemistry of different minerals are discussed.Since many mine tailings are poorly reactive under alkaline conditions,different pretreatment methods and their effects on the mineralogy are reviewed.Possible applications for these materials are also discussed. | Jenni Kiventerä Priyadharshini Perumal Juho Yliniemi Mirja Illikainen | 2020 | International Journal of Minerals,Metallurgy and Materials2020，27，8： | 3 |
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