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| 1 | Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases显示文摘AIM To investigate whether immune mediated diseases(IMD) are more frequent in patients with inflammatory bowel disease(IBD).METHODS In this population based registry study,a total of 47325 patients with IBD were alive and registered in the Danish National Patient Registry on December 16,2013. Controls were randomly selected from the Danish Civil Registration System(CRS) and matched for sex,age,and municipality. We used ICD 10 codes to identify the diagnoses of the included patients. The IBD population was divided into three subgroups: Ulcerative colitis(UC),Crohn's disease(CD) and Both the latter referring to those registered with both diagnoses. Subsequently,odds-ratios(OR) and 95%CI were obtained separately for each group and their respective controls. The use of Bonferoni post-test correction adjusted the significance level to P < 0.00125. P-values were estimated using Fisher's exact test.RESULTS There were significantly more women than men in the registry,and a greater percentage of comorbidity in the IBD groups(P < 0.05). Twenty different IMDs were all significantly more frequent in the IBD group. Sixteen were associated with UC versus twelve with CD. In both UC and CD ORs were significantly increased(P < 0.00125) for primary sclerosing cholangitis(PSC),celiac disease,type 1 diabetes(T1D),sarcoidosis,asthma,iridocyclitis,psoriasis,pyoderma gangrenosum,rheumatoid arthritis,and ankylosing spondylitis. Restricted to UC(P < 0.00125) were autoimmune hepatitis,primary biliary cholangitis,Grave's disease,polymyalgia rheumatica,temporal arteritis,and atrophic gastritis. Restricted to CD(P < 0.00125) were psoriatic arthritis and episcleritis. Restricted to women with UC(P < 0.00125) were atrophic gastritis,rheumatoid arthritis,temporal arteritis,and polymyalgia rheumatica. Restricted to women with CD were episcleritis,rheumatoid arthritis,and psoriatic arthritis. The only disease restricted to men(P < 0.00125) was sarcoidosis. CONCLUSION Immune mediated diseases were significantly more frequent in patients with IBD. Our results strengthen the hypothesis that some IMDs and IBD may have overlapping pathogenic pathways. | Morten L Halling Jens Kjeldsen Torben Knudsen Jan Nielsen Lars Koch Hansen | 2017 | World Journal of Gastroenterology2017，23，33： | 9 |
| 2 | High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer显示文摘 | Mads H. Rasmussen Niels F. Jensen Line S. Tarpgaard Camilla Qvortrup Maria U. R?mer Jan Stenvang Tine P. Hansen Lise L. Christensen Jan Lindebjerg Flemming Hansen Benny V. Jensen Torben F. Hansen Per Pfeiffer Nils Brünner Torben F. ?rntoft Claus L. Anders | 2013 | Molecular Oncology2013，，3： | 2 |
| 3 | Preop- erative physical optimization in fast-track hip and knee arthroplasty 显示文摘 | Torben Ba Hansen Helene Kae Bredtoft-Kristian Larsen | 2012 | Danish medical journal2012，59，2： | 1 |
| 4 | Recycled aggregates and recycled aggregate concrete second state-of-the-art report developments 1945–1985显示文摘 | Torben C. Hansen | 1986 | Materials and Structures1986，，3： | 1 |
| 5 | Preoperative lateral subluxation of the patella is a predictor of poor early outcome of Oxford phase-III medial unicompartmental knee arthroplasty显示文摘 | Stig Munk Anders Odgaard Frank Madsen Jesper Dalsgaard Lars Peter Jorn Otto Langhoff Claus Fink Jepsen Torben B?k Hansen | 2011 | Acta Orthopaedica2011，，5： | 1 |
| 6 | Recycled aggregates and recycled aggregate concrete second state-of-the-art report developments 1945–1985显示文摘 | Torben C. Hansen | 1986 | Materials and Structures1986，，3： | 1 |
| 7 | Recycled aggregates and recycled aggregate concrete second state-of-the-art report developments 1945–1985显示文摘 | Torben C. Hansen | 1986 | Materials and Structures1986，，3： | 1 |
| 8 | Recycled aggregates and recycled aggregate concrete second state-of-the-art report developments 1945–1985显示文摘 | Torben C. Hansen | 1986 | Materials and Structures1986，，3： | 1 |
| 9 | Strength of Recycled Concrete Made from Crushed Concrete Coarse Aggregate 显示文摘 | Torben C Hansen Henrik N | 1983 | Concrete International1983，，1： | 1 |
| 10 | Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: Studies in 6018 whites显示文摘 | Dorit P. Jensen S?ren A. Urhammer Hans Eiberg Knut Borch-Johnsen Torben J?rgensen Torben Hansen Oluf Pedersen | 2006 | Molecular Genetics and Metabolism2006，，4： | 1 |
| 11 | The HvNAC6 transcription factor: a positive regulator of penetration resistance in barley and Arabidopsis显示文摘 | Michael Krogh Jensen Jesper Henrik Rung Per Langkjaer Gregersen Torben Gjetting Anja Thoe Fuglsang Michael Hansen Nina Joehnk Michael Foged Lyngkjaer David B. Collinge | 2007 | Plant Molecular Biology (-)2007，，1： | 1 |
| 12 | Mutation analysis of the preproghrelin gene: No association with obesity and type 2 diabetes显示文摘 | Lesli H. Larsen Anette P. Gjesing Thorkild I.A. S?rensen Yasmin H. Hamid S?ren M. Echwald S?ren Toubro Eva Black Arne Astrup Torben Hansen Oluf Pedersen | 2005 | Clinical Biochemistry2005，，5： | 1 |
| 13 | Predicting online grocery buying intentions:a comparison of the theory of reasoned action and the theory of planned behavio r显示文摘 | Torben Hansen Jan Moiler Jensen etal | 2004 | International Journal of Information Management2004，24，： | 1 |
| 14 | Predicting Online Grocery Buying Intentions:A Comparison of the Theory of Reasoned Action and the Theory of Planned Behavior 显示文摘 | Torben Hansen Jan Moller Jensen Hans Stubbe Solgaard | 2004 | International Journal of Information M an agement2004，24，6： | 1 |
| 15 | Accelerated perioperative care and rehabilitation intervention ~br hip and knee replacement is effective-A randomized clinical trial involving 87 patients with 3 months of follow-up 显示文摘 | Kristian Larsen Ole Gade Sorensen Torben B Hansen et a/ | 2008 | Acta Orthopaedica2008，79，2： | 1 |
| 16 | Clinical measurements of the testes in boys and men显示文摘 | Hansen PF Torben KW | 1951 | Acta Ned Scand1951，142，2： | 1 |
| 17 | Physical structure of hardened cement paste. A classical approach显示文摘 | Torben C. Hansen | 1986 | Materials and Structures1986，，6： | 1 |
| 18 | Measurements of nitrogen dioxide on Funen using diffusion tubes 显示文摘 | Marianne Glasius Morten Funch Carlsen Torben Stroyer Hansen | 1999 | Atmospbedc Environment1999，33，： | 1 |
| 19 | Risk of recurrence in patients with colon cancer stage II and III: A systematic review and meta-analysis of recent literature显示文摘 | Camilla B? ckelman Bodil E. Engelmann Tuomas Kaprio Torben F. Hansen Bengt Glimelius | 2015 | Acta Oncologica2015，，1： | 1 |
| 20 | Recycled Concrete Aggregate and Fly Ash Produce Concrete Without Portland Cement显示文摘 | Torben C Hansen | 1990 | CCR1990，，20： | 1 |
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