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4篇 您的检索式:作者名="Thomas FREUDE"
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1100 GHz silicon–organic hybrid modulator显示文摘Electro-optic modulation at frequencies of 100 GHz and beyond is important for photonic-electronic signal processing at the highest speeds.To date,however,only a small number of devices exist that can operate up to this frequency.In this study,we demonstrate that this frequency range can be addressed by nanophotonic,silicon-based modulators.We exploit the ultrafast Pockels effect by using the silicon–organic hybrid(SOH)platform,which combines highly nonlinear organic molecules with silicon waveguides.Until now,the bandwidth of these devices was limited by the losses of the radiofrequency(RF)signal and the RC(resistor-capacitor)time constant of the silicon structure.The RF losses are overcome by using a device as short as 500 μm,and the RC time constant is decreased by using a highly conductive electron accumulation layer and an improved gate insulator.Using this method,we demonstrate for the first time an integrated silicon modulator with a 3dB bandwidth at an operating frequency beyond 100 GHz.Our results clearly indicate that the RC time constant is not a fundamental speed limitation of SOH devices at these frequencies.Our device has a voltage–length product of only V_(π)L=11 V mm,which compares favorably with the best silicon-photonic modulators available today.Using cladding materials with stronger nonlinearities,the voltage–length product is expected to improve by more than an order of magnitude.Luca Alloatti Robert Palmer Sebastian Diebold Kai Philipp Pahl Baoquan Chen Raluca Dinu Maryse Fournier Jean-Marc Fedeli Thomas Zwick Wolfgang Freude Christian Koos Juerg Leuthold 2014Light(Science & Applications)2014,3,1:3
2Open wedge re-correction high tibial osteotomy in an elderly patient with a varus angulated non-united dome-shaped high tibial osteotomy显示文摘The high tibial osteotomy(HTO)is a wellestablished and commonly used treatment for younger and active patients with a medial unicompartmental osteoarthritis of the knee and varus malalignment.The aim of this technique is to shift the load to a functional lateral compartment in order to delay total knee arthroplasty.The dome-shaped HTO was introduced by Blaimont et al.(1975)and later popularized by Maquet(1980).Out of 118 cases,96 cases of overcorrection,13 cases of undercorrection,and 9 casesSteffen SCHROTER Lukas KONSTANTINIDIS Tobias M. KRAUS Fabian STUBY Ulrich STOCKLE Thomas FREUDE 2013Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2013,14,11:2
3Apoptosis is Initiated by Myocardial Ischemia and Executed During Reperfusion显示文摘Bernd Freude Thomas N. Masters Francis Robicsek Alexander Fokin Sava Kostin René Zimmermann Claudia Ullmann Silja Lorenz-Meyer Jutta Schaper 2000Journal of Molecular and Cellular Cardiology2000,,2:1
4Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer’s disease显示文摘Oliver St?hr Katharina Schilbach Lorna Moll Moritz M. Hettich Susanna Freude F. Thomas Wunderlich Marianne Ernst Johanna Zemva Jens C. Brüning Wilhelm Krone Michael Udelhoven Markus Schubert 2013AGE2013,,1:1
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