|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | H2S protects PC12 cells against toxicity of corticosterone by modulation of BDNF-TrkB pathway显示文摘 | Shenglan Gao Wenting Li Wei Zou Ping Zhang Ying Tian Fan Xiao Hongfeng Gu Xiaoqing Tang | 2015 | Acta Biochimica et Biophysica Sinica2015，47，11： | 6 |
| 3 | Anti-inflammatory effects of a synthetic peptide derived from pigment epithelium-derived factor on H2O2-induced corneal injury in vitro显示文摘 | Lu Yi Feng Jia Yang Lili Tang Hongfeng Jin Ji Xu Xun | 2014 | Chinese Medical Journal2014，，8： | 6 |
| 4 | The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells显示文摘 | Junbao Du Yan Hui Yiufai Cheung Geng Bin Hongfeng Jiang Xiaobo Chen Chaoshu Tang | 2004 | Heart and Vessels2004，，2： | 3 |
| 5 | Reaction experiments between tonalitic melt and mantle olivine and their implications for genesis of high-Mg andesites within cratons显示文摘High-Mg(Mg#>45)andesites(HMA)within cratons attract great attention from geologists.Their origin remains strongly debated.In order to examine and provide direct evidence for previous assumptions about HMA’s genesis inferred from petrological and geochemical investigations,we performed reaction experiments between tonalitic melt and mantle olivine on a six-anvil apparatus at high-temperature of 1250–1400°C and high-pressure of 2.0–5.0 GPa.Our experiments in this work simulated the interaction between the tonalitic melt derived from partial melting of eclogitized lower crust foundering into the Earth’s mantle and mantle peridotite.The experimental results show that the reacted melts have very similar variations in chemical compositions to the HMAs within the North China Craton.Therefore,this interaction is probably an important process to generate the HMAs within crations. | WANG MingLiang TANG HongFeng | 2013 | Science China Earth Sciences2013，56，11： | 3 |
| 6 | Petrogenesis of Karamaili alkaline A-type granites from East Junggar, Xinjiang ( NW China) and their relationship with fin mineralization显示文摘 | Su Yuping Tang Hongfeng Sylvester Paul J | 2007 | Geochem J2007，41，： | 1 |
| 7 | Redistribution of REEs during metamorphism and its indicative significance for fluid processes显示文摘 | Congqiang Liu Hongfeng Tang | 1999 | Science in China Series D: Earth Sciences1999，，6： | 1 |
| 8 | The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells显示文摘 | Junbao Du Yan Hui Yiufai Cheung Geng Bin Hongfeng Jiang Xiaobo Chen Chaoshu Tang | 2004 | Heart and Vessels2004，，2： | 1 |
| 9 | Associations of prediabetes with all-cause and cardiovascular mortality: A meta-analysis显示文摘 | Yi Huang Xiaoyan Cai Peisong Chen Weiyi Mai Hongfeng Tang Yuli Huang Yunzhao Hu | 2014 | Annals of Medicine2014，，8： | 1 |
| 10 | Effects of Chronic Mild Stress on the Development of Atherosclerosis and Expression of Toll-Like Receptor 4 Signaling Pathway in Adolescent Apolipoprotein E Knockout Mice显示文摘 | Hongfeng Gu Chaoke Tang Kuang Peng Hui Sun Yongzong Yang Terry Delovitch | 2009 | Journal of Biomedicine and Biotechnology2009，，： | 1 |
| 11 | Redistribution of REEs during metamorphism and its indicative significance for fluid processes显示文摘 | Congqiang Liu Hongfeng Tang | 1999 | Science in China Series D: Earth Sciences1999，，6： | 1 |
| 12 | Formaldehyde accelerates cellular senescence in HT22 cells: possible involvement of the leptin pathway显示文摘甲醛(FA ) ,一种著名环境污染物质,是在民族生活的广泛地使用的化学混合物。深刻研究证明了 FA 在中央神经系统上有有毒的效果[1 ] 。然而,位于导致 FA 的 neurotoxicity 下面的机制充分没被调查。发现一个方法阻止并且慢下来引起 FA 的 neurotoxicity 的前进也是必要的。细胞的老朽,导致永久房间周期拘捕的规划房间回答,能被象 oncogene 激活,照耀, DNA 损坏和氧化应力那样的各种各样的细胞的压力导致[2 ] 。最近的研究建议了在大脑的衰老的房间可以贡献 neurodegenerative 变化[3 ] 。有趣地,积累了 FA 在使个人变老的大脑被报导了并且贡献年龄相关的 neurodegenerative 症状[4 ] 。因此, FA 能加速细胞的老朽,这被假设并且它可以接着贡献得到 FA 的 neurotoxicity。 | Kebin Zhan Min Ning Chunyan Wang Yonghong Tang Hongfeng Gu Canqun Yan Xiaoqing Tang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，8： | 0 |
| 13 | Thermodynamic properties of San Carlos olivine at high temperature and high pressure显示文摘In this study, the thermal expansion and heat capacity of San Carlos olivine under high temperature and high pressure are reported. Combining accurate sound velocity data under different P–T conditions with density and heat capacity data at ambient pressure, the density,adiabatic bulk modulus, shear modulus, and most importantly, thermal expansion and heat capacity, of San Carlos are extracted to 14 GPa by a numerical procedure using classic thermodynamic relationships. These data are in agreement with published findings. To estimate the temperature gradient in the upper mantle, we also report the fitting equations of thermal expansion and heat capacity of San Carlos olivine as a function of both temperature and pressure to the P–T condition of the 410 km discontinuity,which provide the thermodynamic properties with increasing depth in the Earth's interior. | Chang Su Yonggang Liu Wei Song Dawei Fan Zhigang Wang Hongfeng Tang | 2018 | Acta Geochimica2018，37，2： | 0 |
| 14 | Experimental study on reactions between alkaline basaltic melt and orthopyroxenes: constraints on the evolution of lithospheric mantle in the North China Craton显示文摘The experimental results of the reactions between an alkaline basaltic melt and mantle orthopyroxenes under high-temperature and high-pressure conditions of 1300–1400℃ and 2.0–3.0 GPa using a six-anvil apparatus are reported in this paper.The reactions are proposed to simulate the interactions between melts from the asthenospheric mantle and the lithospheric mantle.The starting melt in the experiments was made from the alkaline basalt occurring in Fuxin,Liaoning Province,and the orthopyroxenes were separated from the mantle xenoliths in Damaping,Hebei Province.The results show that clinopyroxenes were formed in all the reactions between the alkaline basaltic melt and orthopyroxenes under the studied P–T conditions.The formation of clinopyroxene in the reaction zone is mainly controlled by dissolution–crystallization,and the chemical compositions of the reacted melt are primarily infl uenced by the diff usion eff ect.Temperature is the most important parameter controlling the reactions between the melt and orthopyroxenes,which has a direct impact on the melting of orthopyroxenes and the diff usion of chemical components in the melt.Temperature also directly controls the chemical compositions of the newly formed clinopyroxenes in the reaction zone and the reacted melt.The formation of clinopyroxenes from the reactions between the alkaline basaltic melt and orthopyroxenes can result in an increase of CaO and Al_(2)O_(3) contents in the rocks containing this mineral.Therefore,the reactions between the alkaline basaltic melt from the asthenospheric mantle and orthopyroxenes from the lithospheric mantle can lead to the evolution of lithospheric mantle in the North China Craton from refractory to fertile with relatively high CaO and Al 2 O 3 contents.In addition,the reacted melts in some runs were transformed from the starting alkaline basaltic into tholeiitic after reactions,indicating that tholeiitic magma could be generated from alkaline basaltic one via reactions between the latter and orthopyroxene. | Hanqi He Mingliang Wang Hongfeng Tang | 2024 | Acta Geochimica2024，43，2： | 0 |
| 15 | A systematic assessment of hydroxyapatite nanoparticles used in the treatment of melanoma显示文摘Nano Research volume 13,pages2106–2117(2020)Cite this article 106 Accesses 1 Altmetric Metrics details Abstract Melanoma is a highly malignant skin tumor which is prone to recurrence and metastasis.Hydroxyapatite nanoparticles(nHAPs)were reported to possess a suppressive effect on proliferation of various tumor cells in vitro.This study aimed to assess in vitro and in vivo anti-tumor ability and biosafety of the nHAPs used in the treatment of melanoma.Three types of nHAPs with different morphology and crystallinity were synthesized.In vitro cell viability and proliferation studies demonstrated that all three types of nHAPs can inhibit viability and proliferation of A375 and SK-MEL-28 melanoma cells in a concentration-dependent manner.In addition,the rod-shape nHAPs with a crystallinity of 45.60%had the most prominent suppressive effect on the two melanoma cells tested.An important positive regulator of G1/S phase transition in cell cycle,Cyclin D1 protein,was reduced by nHAPs treatment in vivo.We further discovered that the migration ability of the nHAPs treated melanoma cells was greatly decreased.RNA sequencing result revealed that melanoma metastasis related genes were down-regulated by nHAPs,including MMP2,MMP14,ITGA9,ITGB3,ITGB4 and S100B.High concentration of nHAPs treatment in melanoma-bearing nude mice showed a strong inhibitory effect on tumor size and weight.Most importantly,hemolysis,electrolyte disturbance or inflammation response was not discovered in the experimental animals from nHAPs treated groups.We proved that the nHAPs synthesized in the current study has a selective effect to suppress melanoma tumor proliferation and was safe with regard to normal cells and tissue. | Zhongtao Li Jiaoqing Tang Hongfeng Wu Zhixin Ling Siyu Chen Yong Zhou Bo Guo Xiao Yang Xiangdong Zhu Lin Wang Chongqi Tu Xingdong Zhang | 2020 | Nano Research2020，13，8： | 0 |
| 16 | REE geochemical constraints on the genesis of synmetamorphic veins in Xingzi Group of Lushan, SE China显示文摘METAMORPHIC fluids, an important type of the ore-forming fluids within the Earth’ s crust, are the necessary materials for metamorphic hydrothermal ore formation. Their direct products are varieties of synmetamorphic veins occurring in metamorphic rocks’. Studies on the genesis of these veins can be availablefor investigating the source material and formation processes of metamorphic hydrothermal deposit. Previous studies on metamorphic veins have focused mainly on their mineralogical, major elemental and oxygenisotopic compositions, and two different hypotheses have been advanced to account for metamorphicvein genesis. In this paper, we use rare-earth elemental method, together with field geological andpetrologic studies, to inquire into the origin of synmetamorphic veins occurring in Xingzi Group ofLushan, southeast China. | TANG Hongfeng and LIU Congqiang Open Laboratory of Ore Deposit Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China | 1999 | Chinese Science Bulletin1999，44，S2： | 0 |
| 17 | Reaction between basaltic melt and orthopyroxene at 3.0–4.5 GPa:Implications for the evolution of ocean island basalts in the mantle显示文摘Interactions between basaltic melt and orthopyroxenite(Opx)were investigated to gain a better understanding of the consequences of the residence and transport of ocean island basalts(OIBs)within the mantle.The experiments were conducted using a DS-3600 six-anvil apparatus at 3.0–4.5 GPa and 1300–1450℃.The basaltic melt and Opx coexisted at local equilibrium at these pressures and temperatures;the initial melts dissolved Opx,which modified their chemical composition,and clinopyroxene(Cpx)precipitated with or without garnet(Grt).The trace-element contents of Grt,Cpx,and melt were measured and the mineral–melt distribution coefficients(D)of Cpx–melt and Grt–melt were calculated,which can be used to assess the distribution of trace elements between basalt and minerals in the mantle.Two types of reaction rim were found in the experimental products,Cpx,and Cpx+Grt;this result indicates that residual rocks within the mantle should be pyroxenite or garnet pyroxenite.Both rock types are found in mantle xenoliths from Hawaii,and the rare-earth-element(REE)pattern of Cpx in these mantle pyroxenites matches those of Cpx in the experimental reaction rims.Furthermore,residual melts in the experimental products plot in similar positions to Hawaiian high-SiO_(2)OIBs on major-element Harker diagrams,and their trace-element patterns show the signature of residual Grt,particularly in runs at1350℃ and 4.0–4.5 GPa.Trace-element concentrations of the experimental residual melts plot in similar positions to the Hawaiian OIBs on commonly used discrimination diagrams(Ti vs.Zr,Cr vs.Y,Cr vs.V,Zr/Y vs.Zr,and Ti/Y vs.Nb/Y).These results indicate that reaction between basaltic melt and pyroxenite might contribute to the generation of Hawaiian high-SiO2 OIBs and account for their chemical variability. | Chunjuan Zang Mingliang Wang Hongfeng Tang Hanqi He | 2021 | Geoscience Frontiers2021，12，2： | 0 |
| 18 | Adsorption of trichlorphon on phyllosilicate minerals:Effect of low-molecular-weight organic acids显示文摘The use of trichlorphon in large quantities causes a large number of organic pollutants to enter water, sediments, and soils. Phyllosilicate minerals are considered effective adsorbents for organic pollutants. However, the adsorption behavior of organic pollutants on soil minerals affected by low-molecular-weight organic acids(LMWOAs) is not fully understood. In this study, the effect of LMWOAs on the adsorption behavior of trichlorphon on phyllosilicate minerals was investigated using a combination of adsorption measurements and molecular spectroscopic techniques(attenuated total reflection-Fourier transform infrared spectroscopy(ATR-FTIR) and X-ray photoelectron spectroscopy(XPS)). The adsorption of trichlorphon onto kaolinite(KAO) and montmorillonite(MON) was suppressed by increasing pH, indicating that electrostatic interaction played a key role in adsorption, especially at low pH. In the presence of citric acid(CA), there was an obvious promotion of trichlorphon adsorption on KAO and MON. In the presence of oxalic acid(OA), the adsorption of trichlorphon on KAO was promoted, whereas the adsorption on MON was inhibited, especially at pH 4.0. The presence of CA and OA increased the adsorption by increasing the exposure of hydrophobic sites of KAO and MON. The results from ATR-FTIR and XPS also indicated that the hydrophobic Si–O sites of phyllosilicate minerals were the preferred adsorption sites for trichlorphon in the presence of CA and OA, probably driven by the hydrophobic effect. However, the weak effect of OA on MON caused an increase in the electrostatic repulsion between MON and trichlorphon molecules, thus inhibiting adsorption. This study is significant for a deeper understanding of self-purification of soil and sediment systems in the presence of organic pollutants. | Hongfeng CHEN Zhouyang HE Mingxia HOU Cilai TANG Yonghong WU | 2024 | Pedosphere2024，34，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员